Micro/Nano-Swimmers, Robots, and Motors: Fabrication and Applications

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Nanoelectronics, Nanosensors and Devices".

Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 1171

Special Issue Editors


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Guest Editor
1. Faculty of Medicine and Health, Ministry of Education, Harbin Institute of Technology, Yikuang Street 2 2H, Harbin 150080, China
2. Tomsk Polytechnic University, 30 Lenin Avenue, Tomsk 634050, Russia
Interests: drug delivery; biological benign; thin films; remote guidance; surface functionalization; analytical techniques
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Guest Editor Assistant
Weinberg Research Center, School of Nuclear Science & Engineering, National Research Tomsk Polytechnic University, Tomsk 634050, Russia
Interests: biocompatible polymers; micro/mano-motors; additively manufactured implants; drug delivery; tissue engineering; surface modification; coatings
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Nanomaterials are, due to their size, able to alter conditions of the surrounding matrix significantly, like adding magnetic properties to polymeric composite thin films. Furthermore, even they are small in form of thin films, they are able to entrap cargo to form drug delivery systems. Recent developments of drug delivery system based micro- and nanomotors show the possibility to finally reach applications, enabling new possibilities to combat diseases like cancer, as well as improve environmental remediation. Some first insights into these applications are displayed by catalytic nano-swimmers utilizing toxic substances as fuel in natural environments, as well as living-nanomotor composite systems able to bypass the blood brain barrier with little or no side effects.

This Special Issue of Nanomaterials aims to present the current state-of-the-art in the fabrication and use of nanoparticles and nanofilms as well as other nanocomposite systems in the field of drug delivery and guidance of micro-/nano-swimmer, robots, and motors. The importance of nanoparticles is based on the fact that they bridge clusters of atoms over microparticles up to solid materials. The importance of nanoparticles and nanofilms is highlighted especially by their surface properties, determining the behavior and biocompatibility of the micro- and nanomotors. In this context, microparticles and films are in the mesoscale bridging the gap to the macroscopic scale. In the present Special Issue, we would like to invite everyone who can significantly contribute to this research field with the aim of giving a balanced view of the current state-of-the-art in this discipline.

Dr. Johannes Frueh
Guest Editor

Dr. Sven Rutkowski
Assistant Guest Editor

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Keywords

  • biomedical applications
  • biocompatibility
  • environmental remediation
  • biological benign fuel
  • biodegradation
  • drug delivery
  • RNA delivery
  • remote guidance

Published Papers (1 paper)

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Research

14 pages, 5696 KiB  
Article
Template-Free Manufacturing of Defined Structure and Size Polymeric Microparticles
by Arkady S. Abdurashitov, Pavel I. Proshin and Gleb B. Sukhorukov
Nanomaterials 2023, 13(22), 2976; https://doi.org/10.3390/nano13222976 - 20 Nov 2023
Cited by 1 | Viewed by 935
Abstract
Complex-structured polymeric microparticles hold significant promise as an advance in next-generation medicine mostly due to demand from developing targeted drug delivery. However, the conventional methods for producing these microparticles of defined size, shape, and sophisticated composition often face challenges in scalability, reliance on [...] Read more.
Complex-structured polymeric microparticles hold significant promise as an advance in next-generation medicine mostly due to demand from developing targeted drug delivery. However, the conventional methods for producing these microparticles of defined size, shape, and sophisticated composition often face challenges in scalability, reliance on specialized components such as micro-patterned templates, or limited control over particle size distribution and cargo (functional payload) release kinetics. In this study, we introduce a novel and reliably scalable approach for manufacturing microparticles of defined structures and sizes with variable parameters. The concept behind this method involves the deposition of a specific number of polymer layers on a substrate with low surface energy. Each layer can serve as either the carrier for cargo or a programmable shell-former with predefined permeability. Subsequently, this layered structure is precisely cut into desired-size blanks (particle precursors) using a laser. The manufacturing process is completed by applying heat to the substrate, which results in sealing the edges of the blanks. The combination of the high surface tension of the molten polymer and the low surface energy of the substrate enables the formation of discrete particles, each possessing semi-spherical or other designed geometries determined by their internal composition. Such anisotropic microparticles are envisaged to have versatile applications. Full article
(This article belongs to the Special Issue Micro/Nano-Swimmers, Robots, and Motors: Fabrication and Applications)
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