Radiation Technology in Nanomaterials

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Biology and Medicines".

Deadline for manuscript submissions: 25 February 2025 | Viewed by 1310

Special Issue Editors


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Guest Editor
Department of Electrical and Computer Engineering, University of Texas at San Antonio (UTSA), One UTSA Circle, San Antonio, TX 78249, USA
Interests: nanomaterials; nanoparticles; synthesis of nanoparticles by gamma radiation; modeling and simulation; optical properties; characterization of nanoparticles
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Electrical and Computer Engineering, University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249-0670, USA
Interests: applied artificial intelligence; smart electric power systems and smart grids; machine learning in national security applications; artificial intelligence in smart cities; intelligent control methods in power systems; intelligent systems for signal processing and detection algorithms; machine learning and pattern recognition; nuclear security and nonproliferation; AI in radiation detection; AI in nuclear power applications
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue focuses on 'Radiation Technology in Nanomaterials', delving into the multifaceted realm of radiation sciences, which intersects with nanotechnology. This publication showcases the extensive applications and innovations in manipulating nanomaterials through radiation exposure. This fusion of disciplines merges the intricate principles of radiation physics and chemistry with the intricate domain of nanoscience. By harnessing various forms of radiation, including gamma rays, X-rays, and electron beams, scientists may wield precise control over nanomaterial properties such as size, structure, and composition. Among these methods, gamma radiation stands out as a powerful tool, facilitating the synthesis of nanomaterials, particularly metal nanoparticles. Gamma radiation initiates radiation-induced processes such as radiolysis and nucleation, enabling the controlled creation of nanoparticles with distinct characteristics. This tailored manipulation empowers the development of nanomaterials that are tailored for a wide spectrum of applications, spanning industries, medicine, and beyond. In industrial sectors, this technology underpins the creation of high-performance materials pivotal for advancements in electronics, energy storage, and environmental remediation. In healthcare, the strategic use of radiation technology crafts nanomaterials and nanoparticles precisely, catering to targeted drug delivery systems, diagnostic imaging agents, and innovative therapeutic treatments. This interdisciplinary landscape is perpetually evolving, exploring novel radiation-based techniques to engineer nanomaterials, diversifying their properties, functionalities, and applications. The synthesis of nanomaterials using radiation-based methods contributes to an expanding array of applications. 

Dr. Elham Gharibshahi
Dr. Miltiadis (Miltos) Alamaniotis
Guest Editors

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Keywords

  • nanomaterials
  • nanocomposites
  • nanoparticles
  • nanofabrication
  • ionizing radiation
  • gamma radiation
  • radiation-induced synthesis
  • radiolytic method
  • radiation detection and radiation effects
  • application of nanomaterials

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Published Papers (1 paper)

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Research

22 pages, 6851 KiB  
Article
Size-Sorted Superheated Nanodroplets for Dosimetry and Range Verification of Carbon-Ion Radiotherapy
by Yosra Toumia, Marco Pullia, Fabio Domenici, Alessio Mereghetti, Simone Savazzi, Michele Ferrarini, Angelica Facoetti and Gaio Paradossi
Nanomaterials 2024, 14(20), 1643; https://doi.org/10.3390/nano14201643 - 13 Oct 2024
Viewed by 915
Abstract
Nanodroplets have demonstrated potential for the range detection of hadron radiotherapies. Our formulation uses superheated perfluorobutane (C4F10) stabilized by a poly(vinyl-alcohol) shell. High-LET (linear energy transfer) particles vaporize the nanodroplets into echogenic microbubbles. Tailored ultrasound imaging translates the generated echo-contrast into a dose [...] Read more.
Nanodroplets have demonstrated potential for the range detection of hadron radiotherapies. Our formulation uses superheated perfluorobutane (C4F10) stabilized by a poly(vinyl-alcohol) shell. High-LET (linear energy transfer) particles vaporize the nanodroplets into echogenic microbubbles. Tailored ultrasound imaging translates the generated echo-contrast into a dose distribution map, enabling beam range retrieval. This work evaluates the response of size-sorted nanodroplets to carbon-ion radiation. We studied how thesize of nanodroplets affects their sensitivity at various beam-doses and energies, as a function of concentration and shell cross-linking. First, we show the physicochemical characterization of size-isolated nanodroplets by differential centrifugation. Then, we report on the irradiations of the nanodroplet samples in tissue-mimicking phantoms. We compared the response of large (≈900 nm) and small (≈400 nm) nanodroplets to different carbon-ions energies and evaluated their dose linearity and concentration detection thresholds by ultrasound imaging. Additionally, we verified the beam range detection accuracy for the nanodroplets samples. All nanodroplets exhibited sensitivity to carbon-ions with high range verification precision. However, smaller nanodroplets required a higher concentration sensitivity threshold. The vaporization yield depends on the carbon-ions energy and dose, which are both related to particle count/spot. These findings confirm the potential of nanodroplets for range detection, with performance depending on nanodroplets’ properties and beam parameters. Full article
(This article belongs to the Special Issue Radiation Technology in Nanomaterials)
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