Non-coding RNAs in Stem Cell Differentiation and Disease

A special issue of Non-Coding RNA (ISSN 2311-553X).

Deadline for manuscript submissions: 28 February 2025 | Viewed by 150

Special Issue Editor


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Guest Editor
Department of Biochemistry and Molecular Biology, University of Bucharest, Bucharest, Romania
Interests: non-coding RNAs; transcriptomics; chromatin conformation; extracellular vesicles; exosomes; human adipose-derived stem cells; stem cell differentiation; neurogenesis; adipogenesis; osteogenesis; tissue engineering; biocompatibility; biomaterials; magnetic nanoparticles
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Special Issue Information

Dear Colleagues,

Non-coding RNAs are molecules that can regulate cell fate both during development and in disease by controlling transcriptional or post-transcriptional mechanisms. Recently, ncRNAs have increasingly been discovered to be crucial multipurpose regulators of all biological processes; therefore, they have gained potential functions as biomarkers or as therapeutic targets. Importantly, the alteration in ncRNA expression has been correlated with different diseases, such as Alzheimer’s, metabolic syndrome/diabetes, or cancer. In stem cell differentiation, these molecules can control cell fate, regulating the commitment of stem cells to a certain lineage. Originating from “the dark matter” of the genome, ncRNAs have been identified in all cell types and in intercellular communication mediated by extracellular vesicles, making them viable candidates for diagnostic, prognostic, and therapeutic targets.

This Special Issue aims to establish the emerging role of ncRNAs both in stem cell differentiation and pathological conditions and to identify the regulatory functions of these molecules. This Special Issue welcomes submissions in the form of original articles, reviews, and short communications. This Special Issue will give readers insights into the latest discoveries and advances regarding ncRNA function in stem cell differentiation, as well as in disease progression and/or prevention.

We look forward to receiving your contributions.

Dr. Sorina Dinescu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Non-Coding RNA is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • ncRNAs
  • miRNAs
  • lncRNAs
  • exosomes
  • intercellular communication
  • tumour microenvironment
  • stem cell differentiation
  • biomarker

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Published Papers

This special issue is now open for submission.
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