Advances in Alzheimer’s Disease and Related Dementias
A special issue of NeuroSci (ISSN 2673-4087).
Deadline for manuscript submissions: closed (31 August 2022) | Viewed by 9399
Special Issue Editor
Interests: surgery
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Alzheimer’s disease and related dementias remain the leading cause of death and disability worldwide. However, the current beta-amyloid (Aβ) and tau-targeting therapies for Alzheimer’s disease failed in the clinical trials, and whether Aβ accumulation is the cause or consequence of Alzheimer’s disease is unclear. Major advances have been made by investigating novel mechanisms underlying neuroinflammation, neuronal death, synaptic dysfunction, cerebrovascular dysfunction etc., which contribute to the development of Alzheimer’s disease and related dementias. The role of risk factors including aging, cardiovascular diseases, and metabolic disorders are also attracting attention by researchers to investigate the novel mechanisms underlying the pathogenesis of Alzheimer’s disease and related dementias. The present Special Issue aims to include research in all the areas related to studies in Alzheimer’s disease and related dementias. We invite manuscripts in the form of original research, reviews, mini-reviews, and short communications investigating/commenting on the novel mechanisms of pathogenesis of Alzheimer’s disease and related dementias.
Potential topics include, but are not limited to:
- Beta-amyloid (Aβ) and tau pathology
- Neuronal death and synaptic dysfunction
- Neuroinflammation
- Risk factors: Lifestyle, cardiovascular diseases, and metabolic disorders et al. in the contribution to Alzheimer's dementia and related dementias
- Cerebrovascular dysfunction, blood–brain barrier leakage, cerebral blood flow dysregulation, neurovascular coupling, cerebrovascular remodeling et al. in Alzheimer's and related dementias
- Immune system in the pathogenesis of Alzheimer's disease and related dementias
- Novel therapies for the treatment of Alzheimer's disease and related dementias.
Dr. Shaoxun Wang
Guest Editor
Manuscript Submission Information
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