Molecular Biology of Papillomaviruses
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Viral Pathogens".
Deadline for manuscript submissions: 30 November 2024 | Viewed by 1189
Special Issue Editors
Interests: mechanisms and DDR regulation of DNA tumor virus genome replication; novel antiviral and anticancer therapeutic approaches; transformation and evolution of cancer
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue of the Pathogens journal will focus on the “Molecular Biology of Papillomaviruses”.
Human papillomaviruses (HPVs) infect epidermal tissues, often via nearly undetectable lesions, and cause a wide variety of pathologies, including over 1 in 20 human cancers (cervical, anogenital, and oropharyngeal, as well as others), and a variety of infections that can range from inconvenient to very serious, particularly for immunocompromised individuals or children with recurrent respiratory papillomatosis. While there are currently vaccines against a handful of the HPV types that most frequently progress to cancer, there are hundreds of HPV types for which there is no vaccine and no effective treatments.
The continuous advancement of molecular biology techniques and approaches has provided a deeper understanding of the molecular biology of HPV infection, life cycle, and the molecular basis of HPV–host interactions. This Special Issue of the Pathogens journal is intended to cover all aspects of papillomavirus molecular biology, which occurs intracellularly during all stages of the infection/viral life cycle, as well as intracellular effects caused by papillomavirus proteins during transformation and extracellular events (such as how viral proteins or nucleic acids interact with host factors). This Special Issue seeks to provide novel information into HPV molecular biology that may provide insights into HPV biology and potential treatment avenues.
In addition to primary research articles, reviews will also be considered for inclusion; if you are considering submitting a review, please contact the Guest Editors prior to initiating such efforts so they can ensure there is not extensive overlap between other submissions.
We look forward to receiving your contributions.
Dr. Thomas Melendy
Dr. Kavi Mehta
Guest Editors
Manuscript Submission Information
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Keywords
- HPV
- papillomavirus
- viral replication
- viral transcription
- episomal maintenance
- DNA damage response
- viral amplification
- differentiation-dependent amplification
- viral life cycle
- HPV host–pathogen interactions
- genetic instability
- genome maintenance
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