Molecular and Cellular Research on Targets for Antimalarial Therapy Development
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Parasitic Pathogens".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 61
Special Issue Editor
Special Issue Information
Dear Colleagues,
Despite concerted efforts to develop chemotherapies and vaccines, nearly half of the world’s population remains at risk of malaria. In 2022, there were an estimated 249 million cases and 608,000 deaths, with Plasmodium falciparum and P. vivax being the primary causes of human disease. While the combined effects of indoor residual spraying, insecticide-treated bed nets, and artemisinin combination therapies reduced malaria incidence and mortality between 2000 and 2015, progress has subsequently stalled. Cases and deaths have both been increasing since 2019 due to insecticide and antimalarial drug resistance, disruptions due to the COVID-19 pandemic, and other factors. Due to acquired resistance mutations in the parasite, there is a desperate need to identify new targets for vaccine or antimalarial development. As unique mechanisms of action are especially desirable, molecular and cellular studies of the parasite and its interactions with the host and vector are needed.
In this Special Issue, we aim to provide a collection of timely research articles, comprehensive reviews, and short communications that relate to molecular and cellular malaria research with an emphasis on translation to much-needed therapies.
I look forward to your involvement in this important Special Issue.
Dr. Sanjay Arvind Desai
Guest Editor
Manuscript Submission Information
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Keywords
- malaria
- molecular biology
- cellular biology
- antimalarial drug discovery and development
- malaria vaccines
