Emerging and Re-emerging Bacterial Infections

A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Emerging Pathogens".

Deadline for manuscript submissions: 30 November 2024 | Viewed by 803

Special Issue Editor


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Guest Editor
Department of Microbiology & Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA
Interests: Bacillus anthracis; bacterial pathogenesis; aerobiology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Bacterial infections account for millions of deaths per year worldwide, and they make up a considerable percentage of all infection-related deaths. Consequently, bacterial infections are a major public health concern. Many of the known bacterial pathogens have subsisted for ages, but over the past few years, advances in modern medicine have given rise to new treatments that have curtailed the frequency of occurrence and disease severity associated with many of these pathogens. However, due to various factors such as improved methods of bacterial identification, increased human exposure to bacteria, and the development of antibiotic resistance, new bacteria have emerged while some well-known bacteria have reemerged.

This Special Issue aims to explore emerging and reemerging bacterial pathogens with special emphasis on new findings on these bacteria and future management.

Dr. William S. Lawrence
Guest Editor

Manuscript Submission Information

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Keywords

  • bacteria
  • human infection
  • emerging infections
  • pathogenesis
  • mutation
  • virulence
  • animal model of infection
  • antibiotic-resistance
  • immunity
  • therapeutics

Published Papers (1 paper)

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Review

14 pages, 1907 KiB  
Review
Emerging and Re-Emerging Pathogens in Valvular Infective Endocarditis: A Review
by Maximilian Reisinger, Mateusz Kachel and Isaac George
Pathogens 2024, 13(7), 543; https://doi.org/10.3390/pathogens13070543 - 27 Jun 2024
Viewed by 486
Abstract
Infective endocarditis (IE) is a microbial infection of the endocardial surface, most commonly affecting native and prosthetic valves of the heart. The epidemiology and etiology of the disease have evolved significantly over the last decades. With a growing elderly population, the incidence of [...] Read more.
Infective endocarditis (IE) is a microbial infection of the endocardial surface, most commonly affecting native and prosthetic valves of the heart. The epidemiology and etiology of the disease have evolved significantly over the last decades. With a growing elderly population, the incidence of degenerative valvopathies and the use of prosthetic heart valves have increased, becoming the most important predisposing risk factors. This change in the epidemiology has caused a shift in the underlying microbiology of the disease, with Staphylococci overtaking Streptococci as the main causative pathogens. Other rarer microbes, including Streptococcus agalactiae, Pseudomonas aeruginosa, Coxiella burnetti and Brucella, have also emerged or re-emerged. Valvular IE caused by these pathogens, especially Staphylococcus aureus, is often associated with a severe clinical course, leading to high rates of morbidity and mortality. Therefore, prompt diagnosis and management are crucial. Due to the high virulence of these pathogens and an increased incidence of antimicrobial resistances, surgical valve repair or replacement is often necessary. As the epidemiology and etiology of valvular IE continue to evolve, the diagnostic methods and therapies need to be progressively advanced to ensure satisfactory clinical outcomes. Full article
(This article belongs to the Special Issue Emerging and Re-emerging Bacterial Infections)
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