Drug Candidates for the Treatment of Endocrinopathies
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmacology".
Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 220
Special Issue Editor
Interests: cell biochemistry; livestock production; genetic engineering techniques; hormones; egg and sperm maturation; recombinant hormones
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
These receptors belong to the subfamily of G protein-coupled receptors (GPCRs) that are phosphorylated in the intracellular and carboxyl‒terminal regions. These glycoprotein hormones display diversity functions in ovulation and the estrus cycle. These glycoproteins and GPCRs were one of the most important molecules during sex maturation in mammalian species. The agonist‒receptor complex is internalized by a dynamin-dependent pathway and moved to the endosome compartment without agonist dissociation. However, exploring the many functions of these hormones through receptors can help us understand the pivotal role in the activating and inactivating receptor and the under signal transduction pathway of PKA, pERK1/2, b-arrestin, and GRKs.
This Special Issue highlights the most recent research in the functions of the glycoprotein hormone and downregulation of these GPCRs. We sincerely invite authors to contribute original research articles focusing on but not limited to the following:
- glycoprotein hormones
- LHCGR
- FSHR
- TSHR
- signal transduction pathway
Prof. Dr. Kwan Sik Min
Guest Editor
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