Emerging Trends in Liquid Chromatography and Mass Spectrometry-Based Analyses of Pharmaceuticals
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: 20 August 2024 | Viewed by 213
Special Issue Editors
Interests: Alzheimer disease; cholinesterase inhibitors; antifungal compounds; metal chelating compounds; anti-biofilm compounds; organic electrosynthesis; organic synthesis; cyclic voltammetry; antioxidant compounds; metabolic profiling of natural compounds
Special Issues, Collections and Topics in MDPI journals
Interests: food biotechnology; food and beverages processes; mass spectrometry
Interests: antioxidants; natural polyphenols; structure-antioxidant activity relationship; mass spectrometry; liquid chromatography; molecular electrochemistry; UV-vis spectroelectrochemistry
Special Issue Information
Dear Colleagues,
Liquid chromatography (LC) coupled with mass spectrometry (MS) can be considered a high-performing technique, widely applied for various purposes, particularly suitable to detect and quantify analytes even in complex matrices and/or in traces. LC-MS analytical methods generally offer improved selectivity, sensitivity and accuracy compared to other methods, especially when tandem mass (MS/MS) techniques or high-resolution mass spectrometry (HRMS) are employed. Among the others, LC-MS analytical methods found wide and successful applications in the pharmaceutical field. For example, LC-MS is useful in pharmacokinetic studies, directed at the detection and quantitation of drugs and their metabolites in a variety of biological matrices, such as blood, brain, plasma, or urine, being crucial throughout the development of new drugs or alternative drug delivery systems.At the same time, drugs and their metabolites are potential environmental contaminants, with possible relevant consequences for human health and ecosystems. LC-MS is a powerful tool for the analysis of drugs and their transformation products in wastewater and soil as well as in environmental monitoring. The aim of this Special Issue is to collect original and review articles related to the recent applications of LC-MS techniques for the identification and quantitation of pharmaceutical compounds, both well-known and potential new drugs, in biological and environmental matrices and in pharmaceutical formulations, to provide the current state of the art of LC-MS applications in the pharmaceutical field.
Dr. Martina Bortolami
Dr. Paola Di Matteo
Dr. Rita Petrucci
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- pharmacokinetic analyses
- drug metabolites
- drug delivery systems
- biological matrices
- environmental samples
- environmental monitoring
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