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Pharmaceuticals publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Nitrogen Containing Scaffolds in Medicinal Chemistry 2023

edited by

Valentina Noemi Madia

and Valeria Tudino

submission deadline 30 Nov 2024 | 5 articles | Viewed by 7496 | Submission Open

Keywords: nitrogen-based heterocycles; bioactive compounds; structure-based drug design; structure-activity relationship; in silico studies; ADMET properties; microwave-assisted synthesis; green chemistry; multicomponent reactions; phytochemicals

(This special issue belongs to the Section Medicinal Chemistry)

Magnetic Nanoparticles (MNPs) in Biomedical Applications

edited by

Sandile Phinda Songca

submission deadline 30 Nov 2024 | 3 articles | Viewed by 7419 | Submission Open

Keywords: magnetic nanoparticles; magnetic resonance imaging; magnetic hyperthermia; cancer therapy; bone therapy; magnetically targeted drug delivery; magnetic hyperthermia drug release; antimicrobial; tissue engineering; biosensors

(This special issue belongs to the Section Pharmaceutical Technology)

Antiradical, Chemopreventive and Antimicrobial Effects of Bioactive Natural Substances

edited by

Grażyna Zgórka

submission deadline 30 Nov 2024 | 4 articles | Viewed by 6466 | Submission Open

Keywords: natural radical scavengers; chemopreventive agents; antimicrobials; chemical and biomedical analysis; biological studies in vitro/in vivo

(This special issue belongs to the Section Natural Products)

HIV and Viral Hepatitis: Prevention, Treatment and Coinfection

edited by

Daniel Sepúlveda-Crespo

and

Salvador Resino

submission deadline 30 Nov 2024 | 4 articles | Viewed by 5942 | Submission Open

Keywords: coinfection; drug discovery; HBV; HCV; HDV; HIV; neutralizing antibodies; prevention; treatment; vaccine

(This special issue belongs to the Section Biopharmaceuticals)

Innovative Tools for Drug Analysis and Therapeutic Drug Monitoring (TDM)

edited by

Juraj Piestansky

and

Andrej Kovac

submission deadline 30 Nov 2024 | 4 articles | Viewed by 4880 | Submission Open

Keywords: therapeutic drug monitoring; analysis of drugs; separation analytical methods; mass spectrometry; bioanalysis; quality control; dosage forms; green analytical chemistry

(This special issue belongs to the Section Pharmacology)

HTLV-1: Molecular Insights to Targeted Elimination Strategies

edited by

Juliana Echevarria Neves de Lima

and

Goedele N. Maertens

submission deadline 30 Nov 2024 | 2 articles | Viewed by 4479 | Submission Open

Keywords: HTLV-1; adult T-cell leukemia/Lymphoma (ATLL); HTLV-1-associated myelopathic/tropical spastic paraparesis (HAM/TSP); treatment; new compounds; drug repositing and immunotherapy

(This special issue belongs to the Section Pharmacology)

Antiviral Agents, 2024

edited by

Luis Octavio Regasini

submission deadline 30 Nov 2024 | 2 articles | Viewed by 2402 | Submission Open

Keywords: antiviral; virus; arbovirus; drugs; protease; helicase; polymerase; reverse transcriptase

(This special issue belongs to the Section Medicinal Chemistry)

Lipid-Nanoparticle-Mediated Delivery of Small-Molecule and Nucleic Acid-Based Therapeutics

edited by

Okhil Kumar Nag

submission deadline 30 Nov 2024 | 1 articles | Viewed by 2251 | Submission Open

(This special issue belongs to the Section Pharmaceutical Technology)

Potential Therapeutic Methods in Reproductive Aging

edited by

Bosun Joo

submission deadline 30 Nov 2024 | 1 articles | Viewed by 1734 | Submission Open

Keywords: ovarian aging; menopause; infertility; ovarian longevity/rejuvernation; angiogenesis; antioxidant; stem cells; platelet-rich plasma

Medicinal Metal Ions and Metal-Based Complex

edited by Rosita Cappai and

Valeria M. Nurchi

submission deadline 30 Nov 2024 | 1 articles | Viewed by 1714 | Submission Open

Keywords: metal complexes; metal-based drugs; medicinal chemistry; chelating agents; solution equilibria

(This special issue belongs to the Section Medicinal Chemistry)

Natural Products Derived from Fungi and Their Biological Activities

edited by

Katarzyna J. Kała

submission deadline 30 Nov 2024 | 1 articles | Viewed by 1677 | Submission Open

Keywords: fungi; medicinal fungi; fruiting bodies; mycelial cultures; bioactive compounds; pro-health activity; mushroom products; natural therapy; natural medicines

(This special issue belongs to the Section Natural Products)

Bioactive Compounds From Plants and Their Therapeutic Applications in Lifestyle-Related Diseases

edited by

Syota Kagawa

and

Agnieszka Ludwiczuk

submission deadline 30 Nov 2024 | 1 articles | Viewed by 1628 | Submission Open

Keywords: natural compounds; lifestyle-related diseases; pharmacology; molecular mechanisms; clinical applications

(This special issue belongs to the Section Natural Products)

Discovery of Novel Antidepressants and Anxiolytics

edited by James Oluwagbamigbe Fajemiroye and Gunnar P. H. Dietz

submission deadline 30 Nov 2024 | 1 articles | Viewed by 1384 | Submission Open

Keywords: biomarkers; depression; anxiety; anxiolytics; antidepressants; preclinical or clinical overview; experimental data; adverse effects; pharmacotherapy options; novel drugs

(This special issue belongs to the Section Pharmacology)

Molecular Imaging of the Tumor Microenvironment

edited by

Hui-Yen Chuang

submission deadline 30 Nov 2024 | 1 articles | Viewed by 1047 | Submission Open

Keywords: molecular imaging; radiopharmaceuticals; tumor microenvironment; immune microenvironment; angiogenesis; pH sensors; theranostics; nanoparticles; drug delivery

(This special issue belongs to the Section Radiopharmaceutical Sciences)

Plant-Based Therapies for Circulatory Disorders

edited by

Priscila De Souza

submission deadline 30 Nov 2024 | 1 articles | Viewed by 779 | Submission Open

Keywords: plant extracts; isolated compounds from medicinal plants; hypertension; dyslipidemia; atherosclerosis; myocardial infarction; cardiac ischemia; heart failure; stroke; kidney disease

Barrier Dynamics and Immune Interplay in Brain Aging and Injury

edited by

Hansen Chen

, Congcong Wang, Xin Wang and Zongshi Qin

submission deadline 30 Nov 2024 | Viewed by 708 | Submission Open

Keywords: aging; neurodegenerative and neurovascular disorders; blood– brain barrier; immune response; adjunct therapy

(This special issue belongs to the Section Pharmacology)

Metal Chelating Agents in Medicinal Chemistry

edited by

Grigoris Zoidis

submission deadline 30 Nov 2024 | Viewed by 250 | Submission Open

Keywords: metal chelating agents; metalloenzymes; metalloenzyme inhibitors

(This special issue belongs to the Section Medicinal Chemistry)

Targeting Opioid Receptors for Innovative Therapies: Present and Emerging Concepts in Opioid Cure

edited by

Piotr Poznanski

Marzena Łazarczyk

and

Dominik Skiba

submission deadline 30 Nov 2024 | Viewed by 245 | Submission Open

Keywords: opioid system; brain injury; pain; neurodegenerative diseases; addiction; cardiovascular diseases; cancer

(This special issue belongs to the Section Medicinal Chemistry)

Advances in Peptide Chemistry and Medicinal Application

edited by

Santo Previti

submission deadline 30 Nov 2024 | Viewed by 236 | Submission Open

Keywords: peptide-based compounds; peptidomimetics; drug discovery; drug-like properties; target modulation; structure– activity relationship studies; unnatural amino acids; backbone modifications; antibodies; hydrogels

(This special issue belongs to the Section Medicinal Chemistry)

Drug Candidates for the Treatment of Pain (2024/2025)

edited by

Marco Fiore

submission deadline 30 Nov 2024 | Viewed by 228 | Submission Open

Keywords: pain; analgesia; drug discovery; drug candidates; new drugs

Innovative Applications and Therapeutic Potential of Cannabinoids

edited by

Anna Stasiłowicz-Krzemień

and

Judyta Cielecka-Piontek

submission deadline 30 Nov 2024 | Viewed by 162 | Submission Open

Keywords: cannabis; cannabinoids; cannabidiol; tetrahydrocannabinol; endocannabinoid system; biopharmaceuticals; pharmacology; drug delivery

(This special issue belongs to the Section Medicinal Chemistry)

Theragnostic Agents Utilized in Magnetic Resonance Imaging (MRI) Advances as Novel Contrast Agents

edited by

Irena Pashkunova-Martic

and Cécile Philippe

submission deadline 30 Nov 2024 | Viewed by 144 | Submission Open

Keywords: cancer theranostics; MRI; high-relaxivity agents; gadolinium-free contrast agents; cancer-targeting ligands; specific MRI agents; drug-loading MRI agents; hyperthermal MRI agents; multifunctional MRI contrast agents

(This special issue belongs to the Section Pharmaceutical Technology)

The 20th Anniversary of Pharmaceuticals—How Artificial Intelligence Is Reshaping Pharmaceuticals Technology

edited by

Serge Mordon

submission deadline 1 Dec 2024 | 8 articles | Viewed by 12328 | Submission Open

Keywords: drug delivery; drug analysis; pharmaceutical technology; controlled release and sustained release; formula design; artificial intelligence

(This special issue belongs to the Section Pharmaceutical Technology)

Inhibition and Treatment in Adhesion, Migration, Invasion, and Metastasis of Cancer Cells

edited by

Magdalena Izdebska

Marta Hałas-Wiśniewska

and Wioletta Zielińska

submission deadline 13 Dec 2024 | 1 articles | Viewed by 616 | Submission Open

Keywords: migration; metastasis; invasion; tumor progression; cell adhesion; cancer; epithelial– mesenchymal transition; cancer therapy

(This special issue belongs to the Section Medicinal Chemistry)

Last Trends of Antileishmanial Drug Discovery and Development

edited by

Annamaria Passantino

and

Michela Pugliese

submission deadline 14 Dec 2024 | Viewed by 128 | Submission Open

Keywords: leishmania; drugs; parasitic treatment; visceral leishmaniasis; canine leishmaniasis; drug resistance; drug targets

(This special issue belongs to the Section Medicinal Chemistry)

Anticancer Compounds in Medicinal Plants — In Honour of the 20th Anniversary of Pharmaceuticals

edited by

Paulo Santos

and

Lillian Barros

submission deadline 15 Dec 2024 | 13 articles | Viewed by 17365 | Submission Open

Keywords: natural products; phytochemicals; cancer; secondary metabolites; medicinal plants

(This special issue belongs to the Section Natural Products)

Natural Pharmacons: Biologically Active Plant-Based Pharmaceuticals 2024

edited by

Dejan Stojković

and

Marina Soković

submission deadline 15 Dec 2024 | 7 articles | Viewed by 7374 | Submission Open

(This special issue belongs to the Section Natural Products)

The 20th Anniversary of Pharmaceuticals: Advances in Peptide Drug Design and Development: From Sequences to Drug Candidates

edited by Juliana C. C. Dallagnol and David Chatenet

submission deadline 15 Dec 2024 | 1 articles | Viewed by 1885 | Submission Open

Keywords: peptide-based drugs; drug design; therapeutic peptides; peptide synthesis; structure– activity relationship; peptide drug delivery; bioavailability; formulation strategies; peptide therapeutics

(This special issue belongs to the Section Biopharmaceuticals)

Medicinal Plants: A Natural Approach to Inflammatory Diseases and Conditions Related to Oxidative Stress

edited by

Sandra Barbalho

and

Adriano Araujo

submission deadline 15 Dec 2024 | 1 articles | Viewed by 822 | Submission Open

Keywords: medicinal plants; phytocompounds; natural products; inflammatory diseases; oxidative stress

(This special issue belongs to the Section Natural Products)

Recent Advances in Behavioral Psychopharmacology

edited by

Agnieszka Pałucha-Poniewiera

submission deadline 15 Dec 2024 | Viewed by 138 | Submission Open

Keywords: addiction; behavioral models; behavioral pharmacology; cognition; depression; drug abuse; memory; psychoactive drugs

(This special issue belongs to the Section Pharmacology)

Small Molecules as Antimicrobials 2024

edited by

Poce Giovanna

submission deadline 15 Dec 2024 | Viewed by 82 | Submission Open

Keywords: small molecules; antimicrobials; antivirals; antibacterials; antimycobacterials

(This special issue belongs to the Section Medicinal Chemistry)

Next-Generation Contrast Agents for Medical Imaging

edited by

Sara Pinto

and

Rafael Aroso

submission deadline 20 Dec 2024 | 9 articles | Viewed by 19185 | Submission Open

Keywords: targeting; contrast agent; medical imaging; radiolabeling; paramagnetic; magnetic resonance imaging; positron emission tomography; optical imaging; SPECT; X-ray

Infectious Disease Epidemiology and Pharmaceutical Development

edited by Victoria Birlutiu,

Simin Aysel Florescu

and Oana Săndulescu

submission deadline 20 Dec 2024 | 8 articles | Viewed by 10312 | Submission Open

Keywords: viral infections; bacterial infections; healthcare-associated infections; tropical diseases; epidemiology of infectious diseases; antibiotic resistance; vaccination; epidemiology of bone and joint infections

(This special issue belongs to the Section Pharmacology)

Rheumatic Diseases: Pathophysiology, Targeted Therapy, Focus on Vascular and Pulmonary Manifestations 2023

edited by

Barbara Ruaro

submission deadline 20 Dec 2024 | 3 articles | Viewed by 5697 | Submission Open

Keywords: rheumatic diseases; pathophysiology; therapy; pulmonary fibrosis; pulmonary arterial hypertension (PAH); imaging techniques

(This special issue belongs to the Section Pharmacology)

Wnt Signaling in Cancer: New Advances

edited by

Danilo Predes

submission deadline 20 Dec 2024 | 1 articles | Viewed by 1731 | Submission Open

Keywords: Wnt signaling; cancer; colorectal cancer; cancer stem cells; stem cells; small molecules; oncogenesis

(This special issue belongs to the Section Pharmacology)

Peptide Drug Conjugates and Their Applications

edited by

Stela Georgieva

and

Petar Todorov

submission deadline 20 Dec 2024 | Viewed by 115 | Submission Open

Keywords: peptides; endogenous opioid peptides; peptidomimetics; neuropeptides; peptide– metal complexes; opioid receptors; chemical biology of peptides

(This special issue belongs to the Section Biopharmaceuticals)

The 20th Anniversary of Pharmaceuticals—Emerging Trends in Biopharmaceuticals

edited by

Alfredo Berzal-Herranz

Gill Diamond

Yan-Ru Lou

and

Nuno Xavier

submission deadline 22 Dec 2024 | 16 articles | Viewed by 35982 | Submission Open

Keywords: proteins; nucleic acids; aptamers; Glycans; macromolecules; antibodies; phages; viruses; therapeutic tools; peptidomimetics

(This special issue belongs to the Section Biopharmaceuticals)

Design, Synthesis and Biological Evaluation with Potential Anti-inflammatory Activity

edited by

Berenika M. Szczȩśniak-Siȩga

Żaneta Czyżnikowska

and

Aleksandra Redzicka

submission deadline 22 Dec 2024 | 2 articles | Viewed by 4052 | Submission Open

Keywords: anti-inflammatory; COX/LOX; IL-6; JAK; STAT3; p38MAPK; TNF-α ; asthma; Alzheimer's disease; cancer

(This special issue belongs to the Section Medicinal Chemistry)

Past, Present and Future Radiotracer Techniques: Radiopharmaceuticals in Cancer Theranostics

edited by

Ute Hennrich

and

Martina Benešová-Schäfer

submission deadline 22 Dec 2024 | 2 articles | Viewed by 2546 | Submission Open

Keywords: diagnostic radiotracers; therapeutic radiopharmaceuticals; theranostics; radiolabeling techniques; GMP compliance; automated synthesis and quality control; pre-clinical studies; translation into clinics and first-in-human studies; clinical trials; regulatory approval

(This special issue belongs to the Section Radiopharmaceutical Sciences)

Medicinal Plants: Current Insights into Their Biological Activities and Integration with Micro- or Nanotechnologies

edited by

Jorge L. Mejía Méndez

Gildardo Sanchez-Ante

and

Edgar R. López-Mena

submission deadline 22 Dec 2024 | 1 articles | Viewed by 1341 | Submission Open

Keywords: medicinal plants; plant extracts; bioactive nanomaterials; inorganic materials; organic materials; drug delivery systems

Therapeutic Potential of Bee Products

edited by Călin Vasile Andriţoiu,

Marcel Popa

and

Lacramioara Ochiuz

submission deadline 22 Dec 2024 | Viewed by 828 | Submission Open

Keywords: Apitherapy; bee products; honey; polen; apilarnil; Royal Jelly; polymer delivery system of apitherapy products

(This special issue belongs to the Section Natural Products)

Pharmacotherapy for Schizophrenia: New Advances

edited by Dennis Kätzel and Holger Rosenbrock

submission deadline 22 Dec 2024 | Viewed by 248 | Submission Open

Keywords: schizophrenia; psychosis; pharmaco-resistance; refractory symptoms; cognitive symptoms; negative symptoms; aberrant salience; drug repurposing; target discovery; drug development; translatable biomarkers; endophenotypes; precision medicine; patient stratification; circuit neuroscience; glutamate hypothesis; dopamine hypothesis; oxidative stress

(This special issue belongs to the Section Pharmacology)

New Platforms for Cancer Treatment—Emerging Advances

edited by Fernanda Karoline Vieira da Silva Torchelsen, Maria Alice de Oliveira, Renata Tupinambá Branquinho and

Vanessa Carla Furtado Mosqueira

submission deadline 22 Dec 2024 | Viewed by 148 | Submission Open

Keywords: cancer treatment; emerging advances; nanotechnology; nanotheranostics; novel drugs; nanostructures; pre-clinical studies

(This special issue belongs to the Section Pharmaceutical Technology)

Antiviral Compounds in Medicinal Plants 2023

edited by

Daniela De Vita

submission deadline 23 Dec 2024 | 6 articles | Viewed by 15103 | Submission Open

Keywords: antiviral agents; viruses; medicinal plants; phytochemicals; natural compounds

(This special issue belongs to the Section Natural Products)

Targeting Apoptosis as a Strategy for Developing New Drugs

edited by

Magdalena Skonieczna

and

Anna Kasprzycka

submission deadline 24 Dec 2024 | 3 articles | Viewed by 4568 | Submission Open

Keywords: proapoptotic drugs; cellular death; death pathways; cell signaling; apoptosis inductors; intracellular death executors; crosstalk of signaling pathways; regulatory cell death (RCD); regulation of cell death

(This special issue belongs to the Section Pharmacology)

Application of 2D and 3D-QSAR Models in Drug Design

edited by

Jaime Mella Raipan

submission deadline 24 Dec 2024 | 3 articles | Viewed by 3837 | Submission Open

Keywords: 2D-QSAR; 3D-QSAR; Hansch analysis; Free– Wilson; structure-activity relationships; CoMFA; CoMSIA; drug design; molecular docking; molecular dynamics.

(This special issue belongs to the Section Medicinal Chemistry)

Topoisomerases as Targets for Novel Drug Discovery

edited by

Andrej Perdih

submission deadline 25 Dec 2024 | 7 articles | Viewed by 20763 | Submission Open

Keywords: topoisomerase; type I topoisomerase; type II topoisomerase; DNA Gyrase; DNA topology; catalytic inhibitors; topo II poisons; DNA gyrase inhibitors; Novel bacterial topoisomerase inhibitors (NBTI); anticancer agents; antibacterial agents

(This special issue belongs to the Section Medicinal Chemistry)

Histamine Receptor Ligands in Medicinal Chemistry

edited by

Krzysztof Walczyński

and

Marek Staszewski

submission deadline 25 Dec 2024 | 6 articles | Viewed by 13430 | Submission Open

Keywords: drug discovery; histamine; receptors; biogenic amines; ligands; antagonist/inverse agonist; affinity/potency; intrinsic activity; pharmacological evaluation; pharmacokinetic evaluation; SAR; CNS diseases; anticancer ligands; allergy; neurodegeneration; cognitive functions; multitarget ligands; molecular modeling; in vitro studies; in silico studies; in vivo studies

(This special issue belongs to the Section Medicinal Chemistry)

Development of Specific Dosage Form: Wound Dressing

edited by

Mihaela Ghica

Madalina Georgiana Albu Kaya

Lacramioara Popa

and Cristina Elena Dinu-Pirvu

submission deadline 25 Dec 2024 | 6 articles | Viewed by 12935 | Submission Open

Keywords: skin lesion; wound healing; wound dressing; regenerative medicine; biomaterials; smart biopolymers; therapeutic system; controlled delivery system; scaffolds; biocompatibility

(This special issue belongs to the Section Pharmaceutical Technology)

Botanicals: Bioactive Molecules and Therapeutic Properties for Human Health 2023

edited by

Sabesan Yoganathan

and

Leonard Barasa

submission deadline 25 Dec 2024 | 5 articles | Viewed by 12285 | Submission Open

Keywords: isolation/characterization of plant metabolites; biosynthesis of medicinal botanicals; chemical synthesis of botanicals; biological activity screening of botanicals; medicinal chemistry evaluation of botanicals; application of computational methods to study bioactive botanicals; phytochemical-derived drug leads

(This special issue belongs to the Section Natural Products)

Displaying special issue 151-200 on page 4 of 7.

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