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Pharmaceuticals publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Recent Advances in Ocular Pharmacology

edited by

Lampros Lamprogiannis

and

Ioannis Tsinopoulos

submission deadline 20 Feb 2026 | 3 articles | Viewed by 7898 | Submission Open

Keywords: ophthalmology; ocular diseases; drug delivery; drug targeting; controlled drug release; eye drops; biopolymers; nanomedicine; clinical applications; clinical trials

(This special issue belongs to the Section Pharmacology)

Heterocyclic Compounds in Medicinal Chemistry, 2nd Edition

edited by

Valentina Noemi Madia

and

Davide Ialongo

submission deadline 20 Feb 2026 | 4 articles | Viewed by 7727 | Submission Open

Keywords: heterocycles; drug design; drug discovery; bioactive compounds; structure-based drug design; structure– activity relationship; in silico studies; ADMET properties; multicomponent reactions; phytochemicals

(This special issue belongs to the Section Medicinal Chemistry)

Discovering Novel Drugs from Plants

edited by

Yung-Chia Chen

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1885 | Submission Open

Keywords: natural products; drug discovery; bioactive compound; extraction; ethnopharmacology; preclinical test

(This special issue belongs to the Section Natural Products)

Pharmacotherapy of Macular Diseases

edited by

Yoichi Sakurada

submission deadline 20 Feb 2026 | 1 articles | Viewed by 486 | Submission Open

Keywords: VEGF inhibitors; macular disorders; neovascular age-related macular degeneration; diabetic macular edema; macular edema associated with retinal vein occlusion

(This special issue belongs to the Section Pharmacology)

Medicinal Chemistry of Thiazine and Oxazine Derivatives: Trends and Future Directions as Therapeutic Drugs

edited by

Berenika M. Szczȩśniak-Siȩga

and

Żaneta Czyżnikowska

submission deadline 22 Feb 2026 | 1 articles | Viewed by 1310 | Submission Open

Keywords: thiazine; oxazine; morpholine; thiomorpholine; benzothiazine; phenothiazine; synthesis; drug; anti-inflammatory; anticancer

(This special issue belongs to the Section Medicinal Chemistry)

Biological Properties of Nanostructures Incorporated in Polymeric Matrices

edited by

Isabella Macário Ferro Cavalcanti

submission deadline 22 Feb 2026 | Viewed by 228 | Submission Open

Keywords: antimicrobial resistance; cancer; diseases; nanotechnology; polimer

(This special issue belongs to the Section Pharmaceutical Technology)

Exploring Biomarkers and Pharmacotherapies for Substance Use Disorders

edited by

Ani Gasparyan

Daniela Navarro

and

Jorge Manzanares

submission deadline 25 Feb 2026 | 4 articles | Viewed by 20670 | Submission Open

(This special issue belongs to the Section Pharmacology)

Medicinal Plants: A Natural Approach to Inflammatory Diseases and Conditions Related to Oxidative Stress

edited by

Sandra Barbalho

and

Adriano Araujo

submission deadline 25 Feb 2026 | 6 articles | Viewed by 20112 | Submission Open

Keywords: medicinal plants; phytocompounds; natural products; inflammatory diseases; oxidative stress

(This special issue belongs to the Section Natural Products)

Development of Novel Radiopharmaceuticals for SPECT and PET Imaging

edited by

Bianca Gutfilen

submission deadline 25 Feb 2026 | 8 articles | Viewed by 12920 | Submission Open

Keywords: oncology; theranostics; inflammation/infection diagnosis; autoimmune diseases; neurodegenerative diseases; cardiovascular diseases

(This special issue belongs to the Section Radiopharmaceutical Sciences)

Therapeutic Potential of Silver Nanoparticles (AgNPs), 2nd Edition

edited by

Goreti Pereira

submission deadline 25 Feb 2026 | 7 articles | Viewed by 10676 | Submission Open

Keywords: metallic nanostructures; plasmonic nanomaterials; photothermal therapy; photodynamic therapy; antimicrobial; antioxidant; anticancer

(This special issue belongs to the Section Medicinal Chemistry)

Advances in Biotechnological Formulations for Skin Disorders: Delivery Strategies and Biocompatibility

edited by Marcel Henrique Marcondes Sari,

Raul Edison Luna Lazo

and

Luana Mota Ferreira

submission deadline 25 Feb 2026 | 1 articles | Viewed by 7001 | Submission Open

Keywords: skin disorders; biotechnological formulations; nanocarriers; probiotic-based formulations; natural products; polysaccharides; skin delivery systems; bioactive compounds; antioxidant and anti-inflammatory effects; wound healing; safety and efficacy in skin therapies

(This special issue belongs to the Section Pharmaceutical Technology)

Self-Assembling Nanostructures for Cancer Therapy

edited by

André Moreni Lopes

submission deadline 25 Feb 2026 | 4 articles | Viewed by 6023 | Submission Open

Keywords: drug delivery systems; polymeric micelles; polymeric vesicles (polymersomes); surfactants; amphiphilic copolymers; stimuli-responsive polymers; cancer therapy; drugs; biopharmaceuticals; dual delivery

(This special issue belongs to the Section Pharmaceutical Technology)

Neuropsychiatric Disorders: Pharmacological Aspects

edited by

Ioana-Miruna Balmus

submission deadline 25 Feb 2026 | 2 articles | Viewed by 4854 | Submission Open

Keywords: neuropsychiatric disorders; DSM-V; pharmacodynamics; innovative therapies; animal models; neuropsychiatric patients; trauma and stress; neurodegeneration; affective disorders; neurodevelopmental disorders; schizophrenia; sleep disorders; comorbidities; cardiovascular; coagulopathies; gastrointestinal; microbiome– gut– brain axis

(This special issue belongs to the Section Pharmacology)

Treatment and Molecular Mechanisms of Depression

edited by Zuleide Maria Ignácio and Ricieri Mocelin

submission deadline 25 Feb 2026 | 1 articles | Viewed by 3492 | Submission Open

Keywords: major depressive disorder; molecular mechanisms; neurotransmitters; epigenetic; genetic polymorphisms; inflammation; neuroinflammation; pharmacological strategies; drugs; intracellular signaling

(This special issue belongs to the Section Medicinal Chemistry)

Drug Treatment for Epilepsy

edited by Clarissa Fantin Cavarsan

submission deadline 25 Feb 2026 | 1 articles | Viewed by 1345 | Submission Open

Keywords: epilepsy; anticonvulsant; epileptic syndrome; seizure; epileptogenic; small molecule drugs

(This special issue belongs to the Section Pharmacology)

Innovative Approaches to GABAergic Drug Discovery: From Molecular Mechanisms to Advanced Therapeutics

edited by

Wojciech Kołodziejczyk

and

Donato Colangelo

submission deadline 25 Feb 2026 | 2 articles | Viewed by 1249 | Submission Open

Keywords: GABAergic signaling; GABA receptors; drug discovery; neurological and psychiatric disorders; ligand design; computational drug development; artificial intelligence in pharmacology; high-throughput screening; targeted drug delivery; controlled release systems

(This special issue belongs to the Section Pharmacology)

Innovations in Solid Dispersions for Drug Delivery

edited by Qun Zhou

submission deadline 25 Feb 2026 | Viewed by 527 | Submission Open

Keywords: solid dispersions; chemistry; properties; crystal; delivery systems

(This special issue belongs to the Section Pharmaceutical Technology)

Pharmacological Approaches of Chronic Obstructive Pulmonary Disease (COPD) and Lung Cancer

edited by

Karolina H. Czarnecka-Chrebelska

and

Jinxiang Xi

submission deadline 25 Feb 2026 | Viewed by 454 | Submission Open

Keywords: chronic obstructive pulmonary disease (COPD); inflammasomes; lung cancer (LC); chronic bronchitis; cancer prevention and treatment; therapeutic approaches

(This special issue belongs to the Section Pharmacology)

Advances in Perinatal Pharmacology

edited by

Khaled Abduljalil

and

Raj Badhan

submission deadline 25 Feb 2026 | 1 articles | Viewed by 452 | Submission Open

Keywords: maternal; perinatal; neonatal; pharmacology; placenta; pregnancy

(This special issue belongs to the Section Pharmacology)

Challenges and Emerging Trends in Photopharmacology

edited by Oleksandra Tiapko and Bernadett Bacsa

submission deadline 25 Feb 2026 | Viewed by 421 | Submission Open

Keywords: photopharmacology; ion channels; receptors; protein– ligand interactions; precision medicine; optogenetics

(This special issue belongs to the Section Pharmacology)

Scientific Evidence-Based Applications of Polyamines in Pharmaceuticals Science

edited by Kuniyasu Soda

submission deadline 25 Feb 2026 | Viewed by 326 | Submission Open

Keywords: polyamine; spermine; spermidine; health; senescence; age-related; disease

(This special issue belongs to the Section Pharmacology)

Targeting Epigenetic Regulation for Cancer Therapy

edited by

Bence Raposa

and

John M. Macharia

submission deadline 25 Feb 2026 | Viewed by 203 | Submission Open

Keywords: epigenetics; chromatin remodeling; histone modifications; non-coding RNAs; gene regulation; cancer therapy; epigenetic biomarkers; therapeutic targets

(This special issue belongs to the Section Pharmacology)

Innovative Applications and Performance Optimization of Biodegradable Polymers in Drug Delivery

edited by

Nikolaos D. Bikiaris

submission deadline 25 Feb 2026 | Viewed by 179 | Submission Open

Keywords: biodegradable polymers; drug delivery systems; controlled release; polymeric nanoparticles; targeted drug delivery; in vivo drug delivery; sustained release formulations

(This special issue belongs to the Section Pharmaceutical Technology)

Antiparasitic Essential Oils: Mechanisms of Action, Technological Approaches, and Metabolism

edited by

Damião Pergentino de Sousa

submission deadline 25 Feb 2026 | Viewed by 138 | Submission Open

Keywords: volatile; essential oils; aromatic plants; aromas; protozoa; helminths; Trypanosoma; Leishmania

(This special issue belongs to the Section Natural Products)

Protein Silencing in Pharmaceutical Applications

edited by

Hamidreza Montazeri Aliabadi

submission deadline 25 Feb 2026 | Viewed by 72 | Submission Open

Keywords: siRNA; CRISPR/Cas9; protein silencing; cancer; in vivo; clinical applications

(This special issue belongs to the Section Biopharmaceuticals)

Pharmaceutical Application of Essential Oils and Their Compounds

edited by

Paweł Kwiatkowski

submission deadline 26 Feb 2026 | 1 articles | Viewed by 7170 | Submission Open

Keywords: essential oils; bacteria; fungi; alternative therapy; antimicrobial resistance; mechanism of action

(This special issue belongs to the Section Natural Products)

Adjuvant Therapies for Cancer Treatment: 2nd Edition

edited by

Fuyi Wang

submission deadline 27 Feb 2026 | 7 articles | Viewed by 28284 | Submission Open

Keywords: drug repurposing; combined therapies; new compounds; drug resistance; chemosensitization; antitumoral strategies

(This special issue belongs to the Section Pharmacology)

Challenges in the Development of PET and SPECT Radiotracers: Innovative Ideas with Negative Outcomes

edited by Magali Toussaint and Barbara Wenzel

submission deadline 27 Feb 2026 | 6 articles | Viewed by 6014 | Submission Open

Keywords: radiotracer development; positron emission tomography (PET); single-photon emission computed tomography (SPECT); negative results; diagnostic radiotracers; therapeutic radiopharmaceuticals; radiolabeling; automated synthesis and GMP; pre-clinical studies; medicinal chemistry

(This special issue belongs to the Section Radiopharmaceutical Sciences)

Advances in the Mechanism of Action and the Therapeutic Role of Phytopharmaceuticals

edited by Maria-Eleni Grafakou and

Jörg Heilmann

submission deadline 28 Feb 2026 | 1 articles | Viewed by 10435 | Submission Open

Keywords: medicinal plants; natural products; phytochemistry; biological activities; mechanism of action; biotransformation; microbiome

(This special issue belongs to the Section Natural Products)

Advances in Natural Products: Basic, Therapeutic, and Computational Approaches in Chronic and Infectious Diseases

edited by

Maira Huerta-Reyes

Gil Alfonso Magos-Guerrero

Oscar Barrera-Vázquez

and

Michael Danilenko

submission deadline 28 Feb 2026 | 5 articles | Viewed by 3613 | Submission Open

Keywords: natural products; chronic diseases; infectious diseases; computational; in silico

(This special issue belongs to the Section Natural Products)

Vitamin D and Its Derivatives in Pharmacology: Mechanisms and Therapeutic Applications

edited by

Agnieszka Sliwinska

submission deadline 28 Feb 2026 | 3 articles | Viewed by 2203 | Submission Open

Keywords: vitamin D; synthesis and metabolism; vitamin D derivatives; vitamin D deficiency related diseases; clinical trials on vitamin D and/or its derivatives

(This special issue belongs to the Section Pharmacology)

New Horizons in Drug Development Targeting Depression

edited by

Michał Górski

, Joanna Fojcik, Agnieszka Koźmin-Burzyńska and Marek Krzystanek

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1973 | Submission Open

Keywords: treatment-resistant depression; novel antidepressants; glutamatergic system; personalized medicine; psychoactive therapies

(This special issue belongs to the Section Pharmacology)

Integrating Machine Learning (ML) into Medicinal Chemistry and Cheminformatics, 2nd Edition

edited by

Vartika Tomar

submission deadline 28 Feb 2026 | 1 articles | Viewed by 825 | Submission Open

Keywords: small molecules; molecular descriptors; molecular similarity; structure-based and ligand-based screening; homology modeling; molecular docking; drug– receptor docking; biological activity

(This special issue belongs to the Section Medicinal Chemistry)

Advances in Radionuclide Production and Their Applications in Therapeutic Radiopharmaceuticals

edited by Svetlana Selivanova

submission deadline 28 Feb 2026 | Viewed by 321 | Submission Open

Keywords: radiopharmaceutical sciences; radiochemistry; radiopharmacology; radionuclide production; molecular imaging

(This special issue belongs to the Section Radiopharmaceutical Sciences)

Applications of Pharmacogenomics in Precision Medicine

edited by

Kariofyllis Karamperis

, Branka Zukic and

Fernanda Rodrigues-Soares

submission deadline 28 Feb 2026 | Viewed by 295 | Submission Open

Keywords: personalized medicine; pharmacogenomics; drug– gene interactions; adverse drug reactions; pharmacogenomic biomarkers; multi-omics; population pharmacogenomics; precision therapeutics

(This special issue belongs to the Section Pharmacology)

Pyrazole and Its Derivatives: Drug Design, Synthesis, and Biological Evaluation

edited by

Matteo Lusardi

and

Marco Ponassi

submission deadline 28 Feb 2026 | Viewed by 287 | Submission Open

Keywords: medicinal chemistry; drug design; drug discovery; pyrazole-based compounds; innovative synthesis; structure– activity relationships; biological activities; drug-like properties

(This special issue belongs to the Section Medicinal Chemistry)

Green Synthesis and Biological Applications of Metal Nanoparticles Influenced by Different Seasonal Periods

edited by

Alan Kelbis Oliveira Lima

, Paulo Sérgio Taube and

Gerson Nakazato

submission deadline 28 Feb 2026 | Viewed by 286 | Submission Open

Keywords: nanobiotechnology; metal nanoparticles; green chemistry; biodiversity; seasonality

(This special issue belongs to the Section Pharmacology)

Discovery of Natural Products to Promote the Wound Healing

edited by

Ying Li

submission deadline 28 Feb 2026 | Viewed by 272 | Submission Open

Keywords: natural ingredients; natural biomedical polymers; drug delivery; nanomedicine; hydrogels; wound healing

Therapeutic Applications of Histone Deacetylase (HDAC) Inhibitors

edited by Chao-Wu Yu and Liqiang Chen

submission deadline 28 Feb 2026 | Viewed by 171 | Submission Open

Keywords: HDAC inhibitors; organ fibrosis; rare disease; neurodegenerative disease; antibiotics; anti-cancer

(This special issue belongs to the Section Medicinal Chemistry)

Molecular Insights and Clinical Implications in Geriatric Medicine and Drug Development

edited by

Katarzyna Mądra-Gackowska

Marcin Gackowski

, Kornelia Kędziora-Kornatowska and

Iga Hołyńska-Iwan

submission deadline 28 Feb 2026 | Viewed by 162 | Submission Open

Keywords: older adults; age-related diseases; biomarkers; drug development; molecular modeling; computer-aided drug design; geriatrics in laboratory medicine; laboratory tests in older patients; malnutrition diagnostics; test results versus a clinical image of an older patient

(This special issue belongs to the Section Pharmacology)

New Perspective of Antiviral Drugs

edited by

Grigoris Zoidis

submission deadline 28 Feb 2026 | Viewed by 162 | Submission Open

Keywords: antiviral drugs; antiviral agents; small organic molecules; metal complexes; natural products

(This special issue belongs to the Section Medicinal Chemistry)

Innovations in Integrin-Targeted Drug Delivery: From Peptide Conjugates to Dual-Action Therapeutics

edited by

Kelly Bugatti

Lucia Battistini

and

Andrea Sartori

submission deadline 28 Feb 2026 | Viewed by 131 | Submission Open

Keywords: integrins; peptide-drug conjugates (PDCs); drug delivery; peptide synthesis; dual conjugates

(This special issue belongs to the Section Biopharmaceuticals)

The Emerging Field of Critical Care Psychiatry: Pharmacologic Treatment from ICU to Post-ICU Recovery

edited by Shixie Jiang,

Matthew Gunther

and Jose R. Maldonado

submission deadline 28 Feb 2026 | Viewed by 86 | Submission Open

Keywords: critical care psychiatry; ICU psychiatry; delirium; encephalopathy; cognitive impairment; neurocognitive disorders; dementia; post-intensive care syndrome; depression; anxiety; trauma; insomnia; sleep disturbances; mental health; behavioral health

(This special issue belongs to the Section Pharmacology)

Bioactive Substances and Skin Health: The Role of Pharmacy and Nutrition—Properties and Technology

edited by

Francisco Rivas

, Margarita López-Viota and Rafael Jesús Giménez Martínez

submission deadline 1 Mar 2026 | 5 articles | Viewed by 30436 | Submission Open

Keywords: supplements; bioactive substances; skin health

(This special issue belongs to the Section Pharmaceutical Technology)

Medications: Interactions with Diet, Herbs, Dietary Supplements and Probiotics

edited by

Francisco Rivas

, María Isabel Valverde Merino and Maria José Zarzuelo Romero

submission deadline 1 Mar 2026 | 3 articles | Viewed by 19600 | Submission Open

Keywords: food– drug interactions; dietary supplements; probiotics; herb– drug interaction

(This special issue belongs to the Section Pharmacology)

Innovations in Chemotherapy: From Synthetic to Natural Agents and Combined Therapies

edited by

Stefano Ruga

submission deadline 1 Mar 2026 | 1 articles | Viewed by 334 | Submission Open

Keywords: chemotherapy; immunotherapy; innovative drugs; natural compounds; combination therapy; targeted therapy; customized administration; drug stability; drug storage

(This special issue belongs to the Section Pharmacology)

Advances in Cancer Treatment and Toxicity

edited by

Dinender K. Singla

submission deadline 10 Mar 2026 | 2 articles | Viewed by 2239 | Submission Open

Keywords: oxidative stress; cell signaling; cell death; tissue remodeling; inflammation; molecular mechanisms; heart; muscle; antioxidants; cell therapy; exosomes

(This special issue belongs to the Section Pharmacology)

Pharmacogenomics and Pediatric Pharmacotherapy

edited by

Chakradhara Rao Satyanarayana Uppugunduri

submission deadline 10 Mar 2026 | Viewed by 121 | Submission Open

Keywords: pharmacokinetics; pediatric formulations; pharmacodynamics; drug metabolism; pharmacogenetics; drug transport; ontogeny developmental pattern; modeling; drug safety; simulation; off-label drug use

(This special issue belongs to the Section Pharmacology)

Pharmacokinetics and Pharmacometrics Driving Innovation

edited by

Michel L Campos

Marcelo Gomes Davanço

and

Mariana Millan Fachi

submission deadline 12 Mar 2026 | Viewed by 136 | Submission Open

Keywords: pharmacokinetics; drug development; ADME; bioanalytical methods; bioequivalence; bioavailability; IVIVC; PBBM; PBBK; biopharmacy

(This special issue belongs to the Section Pharmacology)

Innovative Analytical Techniques and Nanotechnology in Natural Products Analysis and Drug Development

edited by Jinchao Wei and

Di Chen

submission deadline 15 Mar 2026 | 1 articles | Viewed by 3306 | Submission Open

Keywords: natural product; Chinese medicine; drug development; analytical technique; nanotechnology; spectrometry; chromatography; sensors; formulation

(This special issue belongs to the Section Natural Products)

Displaying special issue 101-150 on page 3 of 8.

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