Polymer Dietary Fibers and Gut Microbiota

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Polymer Fibers".

Deadline for manuscript submissions: closed (30 June 2022) | Viewed by 2971

Special Issue Editor


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Guest Editor
School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China
Interests: gut microbiota; marine polysaccharides; colitis; inflammatory bowel disease; fermentation; prebiotics; probiotics; obesity; diabetes; carbohydrate-based drugs
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Special Issue Information

Dear Colleagues,

Dietary fibers are a class of functional carbohydrate polymers that we consume every day. Dietary fibers are not absorbed after oral intake. Therefore, when reaching the distal colon, they could be fermented and metabolized by the gut microbiota. During this process, specific microbes from the gut will degrade the fibers and produce short-chain fatty acids. Additionally, certain fibers can promote the growth of specific bacteria in the gut and change the structure of the microbiota. Gut microbiota is a fast-moving field of biomedical research, and dissecting the interactions between gut microbiota and dietary fibers can help us to understand the function and metabolism of these polymers. It is against this backdrop that this Special Issue is being launched, which will focus on studies that explore the interactions between dietary fibers and gut microbiota.

In this Special Issue of Polymers, we sincerely invite you to submit research articles or informative reviews aiming to elucidate the interactions between gut microbiota and dietary fibers. Specifically, we would like to understand how dietary fibers are metabolized by human gut microbiota and what effects dietary fibers have on the composition of the gut microbiota in health and disease. Research articles and reviews to be considered for publication in this issue should focus on the following topics:

  1. Degradation behaviors of dietary fibers (for example, inulin, resistant starch, xylan, pectin) and functional natural polysaccharides by human gut microbiota;
  2. Modulatory effects of dietary fibers and functional natural polysaccharides on the gut microbiota in health and disease;
  3. Isolation of fiber-degrading bacteria from the human gut microbiota;
  4. Multi-omics studies aiming to dissect the interactions between gut microbiota and dietary fibers;
  5. Fermentation products analysis of dietary fibers and functional natural polysaccharides.

Dr. Qingsen Shang
Guest Editor

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Keywords

  • dietary fiber
  • gut microbiota
  • fermentation
  • prebiotics
  • probiotics
  • polysaccharides
  • short-chain fatty acids
  • degradation
  • high-throughput sequencing
  • carbohydrate polymers

Published Papers (1 paper)

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Research

13 pages, 5967 KiB  
Article
Enterotype-Specific Effect of Human Gut Microbiota on the Fermentation of Marine Algae Oligosaccharides: A Preliminary Proof-of-Concept In Vitro Study
by Tianyu Fu, Luning Zhou, Zhiliang Fu, Bin Zhang, Quancai Li, Lin Pan, Chen Zhou, Qing Zhao, Qingsen Shang and Guangli Yu
Polymers 2022, 14(4), 770; https://doi.org/10.3390/polym14040770 - 16 Feb 2022
Cited by 9 | Viewed by 2674
Abstract
The human gut microbiota plays a critical role in the metabolism of dietary carbohydrates. Previous studies have illustrated that marine algae oligosaccharides could be utilized and readily fermented by human gut microbiota. However, the human gut microbiota is classified into three different enterotypes, [...] Read more.
The human gut microbiota plays a critical role in the metabolism of dietary carbohydrates. Previous studies have illustrated that marine algae oligosaccharides could be utilized and readily fermented by human gut microbiota. However, the human gut microbiota is classified into three different enterotypes, and how this may affect the fermentation processes of marine algae oligosaccharides has not been studied. Here, using in vitro fermentation and 16 S high-throughput sequencing techniques, we demonstrate that the human gut microbiota has an enterotype-specific effect on the fermentation outcomes of marine algae oligosaccharides. Notably, microbiota with a Bacteroides enterotype was more proficient at fermenting carrageenan oligosaccharides (KOS) as compared to that with a Prevotella enterotype and that with an Escherichia enterotype. Interestingly, the prebiotic effects of marine algae oligosaccharides were also found to be enterotype dependent. Altogether, our study demonstrates an enterotype-specific effect of human gut microbiota on the fermentation of marine algae oligosaccharides. However, due to the availability of the fecal samples, only one sample was used to represent each enterotype. Therefore, our research is a proof-of-concept study, and we anticipate that more detailed studies with larger sample sizes could be conducted to further explore the enterotype-specific prebiotic effects of marine oligosaccharides. Full article
(This article belongs to the Special Issue Polymer Dietary Fibers and Gut Microbiota)
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