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Polymers
Special Issues
Functional Gel and Their Multipurpose Applications
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Functional Gel and Their Multipurpose Applications

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Smart and Functional Polymers".

Deadline for manuscript submissions: 30 March 2025 | Viewed by 1101

Special Issue Editors

Dr. Wanyu Chen

E-Mail Website
Guest Editor
School of Materials Science and Engineering, Wuhan University of Technology, Wuhan 430070, China
Interests: gel electrolytes; biomedical/pharmaceutical gels; self-healing gels
Prof. Dr. Chaocan Zhang

E-Mail Website
Guest Editor
School of Materials Science and Engineering, Wuhan University of Technology, Wuhan 430070, China
Interests: nanomaterials and nanocomposites; functional and fine polymer materials; gradient functional polymer materials; adsorption and separation functional materials; liquid crystal polymer materials; photonic crystal materials
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Gel is a kind of solid-like material between a liquid and a solid. It is also a very important soft material. In the recent few decades, gel has developed rapidly in various fields and has become a research hotspot with broad applications in drug delivery systems, wound dressing, gel electrolytes, sensors, chromatographic analysis, adhesives, and so on.

Recognizing the importance of gel materials, this Special Issue of Polymers invites contributions addressing several aspects of these fascinating substances, such as biomedical/pharmaceutical gels, gel electrolytes, food industry gels, simulation studies about gel, self-healing gels, gel-based coatings and adhesives, adsorption and separation gels, and gel-based sensors. This list is by no means exhaustive; any original theoretical, experimental, application works or review articles on functional gels that shed new light on their properties, behaviors, or potential uses are welcome as well. This Special Issue aims to provide a comprehensive platform for researchers from diverse backgrounds to share their latest findings and insights, fostering interdisciplinary collaboration and advancing the field of gel science and technology.

Dr. Wanyu Chen
Prof. Dr. Chaocan Zhang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomedical/pharmaceutical gels
  • gel electrolytes
  • food industry gels
  • simulation studies
  • self-healing gels
  • coatings and adhesives
  • adsorption and separation gels
  • sensors

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Published Papers (2 papers)

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13 pages, 3937 KiB  
Article
Sustained Release of Curcumin from Cur-LPs Loaded Adaptive Injectable Self-Healing Hydrogels
by Caixia Wu, Xiaoqun Ning, Qunfeng Liu, Xiaoyan Zhou and Huilong Guo
Polymers 2024, 16(24), 3451; https://doi.org/10.3390/polym16243451 - 10 Dec 2024
Viewed by 398
Abstract
Biological tissue defects are typically characterized by various shaped defects, and they are prone to inflammation and the excessive accumulation of reactive oxygen species. Therefore, it is still urgent to develop functional materials which can fully occupy and adhere to irregularly shaped defects [...] Read more.
Biological tissue defects are typically characterized by various shaped defects, and they are prone to inflammation and the excessive accumulation of reactive oxygen species. Therefore, it is still urgent to develop functional materials which can fully occupy and adhere to irregularly shaped defects by injection and promote the tissue repair process using antioxidant and anti-inflammatory mechanisms. Herein, in this work, phenylboronic acid modified oxidized hyaluronic acid (OHAPBA) was synthesized and dynamically crosslinked with catechol group modified glycol chitosan (GCHCA) and guar gum (GG) into a hydrogel loaded with curcumin liposomes (Cur-LPs) which were relatively uniformly distributed around 180 nm. The hydrogel possessed rapid gelation within 30 s, outstanding injectability and tissue-adaptive properties with self-healing properties, and the ability to adhere to biological tissues and adapt to tissue movement. Moreover, good biocompatibility and higher DPPH scavenging efficiency were illustrated in the hydrogel. And a more sustainable release of curcumin from Cur-LPs-loaded hydrogels, which could last for 10 days, was achieved to improve the bioavailability of curcumin. Finally, they might be injected to fully occupy and adhere to irregularly shaped defects and promote the tissue repair process by antioxidant mechanisms and the sustained release of curcumin for anti-inflammation. And the hydrogel would have potential application as candidates in tissue defect repair. Full article
(This article belongs to the Special Issue Functional Gel and Their Multipurpose Applications)
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14 pages, 4034 KiB  
Article
In Situ Thermosensitive Mucoadhesive Nasal Gel Containing Sumatriptan: In Vitro and Ex Vivo Evaluations
by Aseel Alshraim, Doaa Alshora, Lubna Ashri, Ahlam Alhusaini, Nawal Alanazi and Nisreen M. Safwan
Polymers 2024, 16(23), 3422; https://doi.org/10.3390/polym16233422 - 5 Dec 2024
Viewed by 485
Abstract
The aim of this study was to develop a thermosensitive mucoadhesive (MA) in situ nasal gel for sumatriptan. A 3D response surface methodology (Design of Expert version 11) was employed to formulate nine different formulations. The Pluronic F-127 concentration (X1) and chitosan concentration [...] Read more.
The aim of this study was to develop a thermosensitive mucoadhesive (MA) in situ nasal gel for sumatriptan. A 3D response surface methodology (Design of Expert version 11) was employed to formulate nine different formulations. The Pluronic F-127 concentration (X1) and chitosan concentration (X2) were selected as independent factors. The formulas were studied in terms of pH, clarity, drug content, gelation temperature, gelation time, gel strength, MA strength, viscosity, % release after 5 h, and release kinetics. The optimized formulas were studied for % permeated after 5 h and stability in addition to previous tests. The study of the stability of the optimized formula was performed under accelerated conditions (40 ± 2 °C, 75 ± 5% RH) for 3 months. The outcomes of the optimized formula were a clear gel with a gelation temperature of 33 °C and a reasonable gelation time of less than one minute, and the release and permeation during 5 h were 40% and 50%, respectively. The formulated gel decreased the mucociliary clearance (MCC) and thus increased the retention time in the nasal cavity, resulting in enhancing SMT absorption, which could improve the drug efficacy. Full article
(This article belongs to the Special Issue Functional Gel and Their Multipurpose Applications)
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