Polymer-Based Nanomedicine for Targeted Drug Delivery
A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Polymer Applications".
Deadline for manuscript submissions: closed (20 August 2022) | Viewed by 3040
Special Issue Editors
Interests: drug delivery of traditional Chinese medicine (TCM); biomaterials; nanomedicine; biomimetic membranes; nanoparticles
Interests: biomimetic nanomedicine; polymeric nanoparticle; drug delivery; cancer; tumor microenvironment; biomaterials; cancer nanomedicine
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Nanomedicine is an emerging field that fosters the development of novel concepts in targeted drug delivery and the exploration of innovative treatment strategies to combat major diseases. Targeted drug delivery is used for delivering therapeutics to a patient in a manner that accumulates drugs selectively at the site of action relative to others in the body. These advances are due, in part, to tunable morphological and physicochemical attributes, and help to address poor bioavailability and the targeted delivery of drugs. The selective delivery of various drugs to cells allows high local drug concentrations in the target cells while minimizing toxicity to normal cells. The encapsulation of active pharmaceutical ingredients within nano-size carriers offers several benefits, namely, protection of the therapeutic agents from degradation, their increased solubility and bioavailability, improved pharmacokinetics, reduced toxicity, enhanced therapeutic efficacy, decreased drug immunogenicity, targeted delivery, and simultaneous imaging and treatment options with a single system. Polymer-based nanomedicines with optimized properties are being considered as a new paradigm in the therapy of diseases. Recently “smart” nanomedicines have been developed with high payload capacity to deliver new drugs, target specific cell types or tissues, cross physiological barriers to reach their target, improve the therapeutic window of drugs, and to reduce unwanted side effects.
This Special Issue aims to present novel polymeric nanomedicine-inspired targeted delivery systems, including ligand-targeted polymeric nanoparticles, dendrimers, nanocomposites, and polymer–drug conjugates for the site-specific transport of pharmaceuticals, improved production and characterization techniques for pharmaceutical nanoparticles, and the exploration of alternative routes of administration and delivery strategies. We welcome articles dealing with all aspects of targeted drug-delivery systems based on polymeric nanomedicine and invite researchers and drug developers to publish their original research or review articles with expert opinions and perspectives in the area of therapeutics.
Dr. Mingfeng Qiu
Dr. Faisal Raza
Guest Editors
Manuscript Submission Information
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Keywords
- targeted drug delivery
- controlled release
- polymeric nanomedicine
- nanoparticles
- dendrimers
- micelles
- polymer synthesis
- ligand-targeted nanomedicine
- nanocomposites
- polymer–drug conjugates
- stimuli-responsive nanoparticles
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