Polymers for Tissue Engineering and Regenerative Medicine

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Polymer Applications".

Deadline for manuscript submissions: closed (31 October 2021) | Viewed by 3129

Special Issue Editor


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Guest Editor
Division of Cardiovascular Surgery, Department of Thoracic and Cardiovascular Surgery, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul 03722, Korea
Interests: drug delivery; polymeric scaffolds; cell engineering; regenerative medicine; tissue engineering and regeneration

Special Issue Information

Dear Colleagues,

Polymeric materials have played a significant role in the field of tissue engineering and regenerative medicine in recent decades because of their good performance in biodegradability and biocompatibility. This Special Issue aims to provide new visions for further studies in the field of tissue engineering and regeneration.

This Special Issue covers all the fields related to applications of polymers in cell engineering and regenerative medicine, but special attention will be given to the following aspects:

  • Polymeric scaffolds with a 3D structure;
  • Structure–property relationships of polymeric materials;
  • Biodegradability, biocompatibility, and antibacterial properties of polymeric materials;
  • Biodegradable polymer biomaterials;
  • Polymers for tissue engineering and regeneration;
  • Stem cell engineering; 
  • Drug delivery;
  • Polymers in medicine;

The goal of this Special Issue is to bring together researchers, share ideas, and provide a platform to showcase recent research advances.

Dr. Young-Nam Youn
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (1 paper)

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Research

26 pages, 8722 KiB  
Article
Three-Dimensional Porous Scaffolds Derived from Bovine Cancellous Bone Matrix Promote Osteoinduction, Osteoconduction, and Osteogenesis
by Alda Malagón-Escandón, Mathieu Hautefeuille, Edgar Jimenez-Díaz, Jesus Arenas-Alatorre, José Manuel Saniger, Isidro Badillo-Ramírez, Nadia Vazquez, Gabriela Piñón-Zarate and Andrés Castell-Rodríguez
Polymers 2021, 13(24), 4390; https://doi.org/10.3390/polym13244390 - 15 Dec 2021
Cited by 8 | Viewed by 2659
Abstract
The use of three-dimensional porous scaffolds derived from decellularized extracellular matrix (ECM) is increasing for functional repair and regeneration of injured bone tissue. Because these scaffolds retain their native structures and bioactive molecules, in addition to showing low immunogenicity and good biodegradability, they [...] Read more.
The use of three-dimensional porous scaffolds derived from decellularized extracellular matrix (ECM) is increasing for functional repair and regeneration of injured bone tissue. Because these scaffolds retain their native structures and bioactive molecules, in addition to showing low immunogenicity and good biodegradability, they can promote tissue repair and regeneration. Nonetheless, imitating these features in synthetic materials represents a challenging task. Furthermore, due to the complexity of bone tissue, different processes are necessary to maintain these characteristics. We present a novel approach using decellularized ECM material derived from bovine cancellous bone by demineralization, decellularization, and hydrolysis of collagen to obtain a three-dimensional porous scaffold. This study demonstrates that the three-dimensional porous scaffold obtained from bovine bone retained its osteoconductive and osteoinductive properties and presented osteogenic potential when seeded with human Wharton’s jelly mesenchymal stromal cells (hWJ-MSCs). Based on its characteristics, the scaffold described in this work potentially represents a therapeutic strategy for bone repair. Full article
(This article belongs to the Special Issue Polymers for Tissue Engineering and Regenerative Medicine)
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