Recent Advances and Emerging Applications of Aptamers
A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".
Deadline for manuscript submissions: closed (20 April 2022) | Viewed by 3700
Special Issue Editors
Interests: aptamer selection and characterization; SELEX; aptamer applications; aptamer-based assays; aptasensors; ELONA; SPR; G-quadruplexes; microbiology; NGS; microbial communities; microbial ecology; yeasts
Special Issues, Collections and Topics in MDPI journals
Interests: aptamer selection and characterization; SELEX; aptamer based sensors and assays; biosensor development and application; bioelectrotechnology; bioelectrochemistry
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Aptamers have become a highly promising class of targeting molecules, and have attracted the attention of many scientists in various research areas. Aptamers are known as a special kind of functional nucleic acids, that are able to recognize and bind their target molecules with high affinity and specificity. They are usually selected using an evolutionary method called SELEX. This technology has been extensively modified and optimized over the years and significantly expanded by computational approaches and new sequencing technologies.
The portfolio of aptamers for specific targets (from small molecules over proteins to complex target structures) is increasingly growing. The varied application possibilities of aptamers include areas such as basic research, health (medicine/pharmacy), environmental monitoring or food industry. Aptamers have a very promising potential as theragnostic agents, delivery agents, molecular imaging tools, and as capture or reporter molecules. They have been successfully verified as molecular recognition elements in a wide range of analytical systems, using different detection principles (e.g., electrochemical, optical, acoustic or mass-sensitive methods, colorimetric approaches, fluorescence-based or SPR-based methods). New technologies like nanotechnologies and recent advances in materials sciences and sensor designs support the development of new aptasensors and aptamer-based detection assays.
This Special Issue of Sensors will cover recent advances and emerging applications of aptamers. We welcome submissions that expand the exciting world of aptamers by the presentation of new aptamers and new methods for their selection, by opening up new fields of application, describing new aptasensor designs, or by developing powerful aptamer-based assays.
Research papers and review articles will be considered. We look forward to and welcome your participation in this Special Issue.
Dr. Regina Stoltenburg
Dr. Beate Strehlitz
Guest Editors
Manuscript Submission Information
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Keywords
- aptamers
- affinity molecules
- biomolecular interactions
- aptasensors
- aptamer-based assays
- clinical diagnostics
- environmental analysis
- food analysis
- water analytics
- SELEX
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