Leptospirosis and One Health Approach: Current Status and Future Prospects, 2nd Edition

Dear Colleagues,

Leptospirosis is an emerging zoonotic disease of broad impact on animal production and public health that affects more than 1 million people, with 60,000 deaths per year. The infection has a strong environmental component, and exposure to soil or water contaminated with the urine of reservoir animals (mostly rodents) infected with pathogenic Leptospira is the most common way for humans or animals to contract leptospirosis. The ability of Leptospira to occupy various ecological niches suggests that the pathogen might have evolved from an environmental ancestor through the acquisition of new functions via lateral gene transfers associated with adaptation to new hosts.

In this context, studies focusing on the animal–human–environment interface are important to better understand the ecology of Leptospira in the natural environment and its interactions with animal and human populations, which will help the implementation of prevention and control efforts aimed at reducing the risk of infection.

The 2nd Edition of this Special Issue aims to address the current status and future prospects on leptospirosis in the context of a One Health approach, with a broad emphasis on the animal, human, and environment interface, and papers focusing on relevant aspects such as deeper understanding of the biodiversity of strains that can lead to infections in both humans and animals, Leptospira isolating from environmental samples, molecular epidemiology, improvement of diagnostic methods, and new epidemiological insights are particularly welcome. We invite the submission of reviews, reports, and original research articles.

Dr. Sérgio Santos de Azevedo
Dr. Clebert José Alves
Guest Editors

Manuscript Submission Information

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• leptospirosis
• one health
• animal leptospirosis
• environment
• epidemiology
• control
• diagnosis

• Leptospirosis and One Health Approach: Current Status and Future Prospects in Tropical Medicine and Infectious Disease (16 articles)