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Tropical Medicine and Infectious Disease, Volume 10, Issue 4

April 2025 - 33 articles

Cover Story: Leprosy is a chronic, debilitating and stigmatising mycobacterial disease with a long incubation period. In 2008, the landmark COLEP study showed that single-dose rifampicin post-exposure prophylaxis (PEP) given to close contacts of leprosy cases led to a 57% overall reduction in subsequent leprosy incidence. Since then, further studies on leprosy PEP have been conducted. This review presents evidence for the efficacy, safety and feasibility of various rifamycin-based chemoprophylaxis strategies. Current evidence suggests that rifamycin-based leprosy PEP is feasible, safe, cost-effective and acceptable to both patients with leprosy and their contacts. Additional research is needed to optimise PEP regimens while ensuring adequate monitoring for potential intervention-related harm. View this paper
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Articles (33)

  • Article
  • Open Access
2 Citations
2,100 Views
14 Pages

Desiccation Tolerance of Aedes aegypti and Aedes albopictus Eggs of Northeastern Argentina Origin

  • Mía E. Martín,
  • Elizabet L. Estallo,
  • Luis G. Estrada,
  • Carolina Matiz Enriquez and
  • Marina Stein

This study examines the desiccation tolerance of Aedes aegypti and Aedes albopictus eggs, two major arbovirus vectors, in a subtropical region of Argentina to understand their survival under varying relative humidity (RH) conditions (35%, 68%, and 82...

  • Review
  • Open Access
1,018 Views
11 Pages

The State of Antimicrobial Resistance of Gram-Negative Bacilli in Canada

  • Jeremy Li,
  • Andrew Walkty,
  • Philippe Lagacé-Wiens,
  • James Karlowsky and
  • George Zhanel

In the last two decades, there has been an increase in resistance among Gram-negative bacteria in Canada. From 2007 to 2016, the proportion of ESBL-producing isolates among Escherichia coli and Klebsiella pneumoniae isolates increased from 3.5% to 11...

  • Article
  • Open Access
1 Citations
1,528 Views
15 Pages

Qualitative Study of Nutritional Support-Related Perceptions and Preferences Among Persons Affected by TB, Family Caregivers, and Healthcare Providers in India

  • Balaji Ramraj,
  • Karikalan Nagarajan,
  • Debjani Ram Purakayastha,
  • Major Madhukar,
  • Makesh Kumar,
  • Neha Raj,
  • Sarath Kumar,
  • Banappa S. Unger,
  • Nithin Rajamani and
  • Sampada Dipak Bangar
  • + 7 authors

Evidence on the implementation aspects of nutritional support interventions for persons with TB in India is limited. This qualitative study employed focus group discussions with persons with TB (n = 71), their family caregivers (n = 17), and healthca...

  • Systematic Review
  • Open Access
2 Citations
2,079 Views
19 Pages

Prevalence of Trichomonas vaginalis Among Women in the Chinese Population: A Systematic Review and Meta-Analysis

  • Shuang Li,
  • Jiahui Xu,
  • Sisi Ru,
  • Changjun Hu,
  • Chongyang Liu,
  • Xingquan Sun,
  • Heteng Guo and
  • Xi Zhang

Trichomonas vaginalis (TV) is the most common non-viral sexually transmitted infection (STI) among women worldwide. However, there is little information available regarding the burden of trichomoniasis infection among Chinese women. The aim of the pr...

  • Article
  • Open Access
2,055 Views
14 Pages

Infectivity and Dissemination of Dengue Virus-1 in Different Aedes aegypti Populations Throughout Brazil

  • Amanda Cupertino de Freitas,
  • Ellen Santos,
  • Lívia Baldon,
  • Silvana de Mendonça,
  • Fernanda Oliveira Rezende,
  • Rafaela Moreira,
  • Viviane Sousa,
  • Mariana Lima,
  • Emanuele Silva and
  • Flávia Ferreira
  • + 13 authors

Dengue virus, one of the most prevalent mosquito-borne flaviviruses affecting humans globally, is primarily transmitted by the Aedes aegypti mosquito, which thrives in densely populated urban environments. Dengue incidence has surged in recent decade...

  • Article
  • Open Access
1,100 Views
16 Pages

The Incidence of Scabies in Far North Queensland, Tropical Australia: Implications for Local Clinical Practice and Public Health Strategies

  • Mert Hamdi Korkusuz,
  • Maria Eugenia Castellanos,
  • Linton R. Harriss,
  • Allison Hempenstall,
  • Simon Smith and
  • Josh Hanson

The recognition and treatment of scabies has been incorporated into Australian guidelines for the prevention of acute rheumatic fever (ARF) and rheumatic heart disease (RHD). The incidence of both diagnosed ARF and RHD is increasing in Far North Quee...

  • Case Report
  • Open Access
2,174 Views
10 Pages

Non-O1, Non-O139 Vibrio cholerae Bacteremic Skin Infection with Multiple Skin Necrosis: Case Report

  • Amer Ibrahim Alomar,
  • Nasreldin Elhadi,
  • Lamya Zohair Yamani,
  • Reema Allahham,
  • Rana Alghamdi,
  • Ibrahim Alhabib,
  • Asim Diab,
  • Nehal Mahmoud,
  • Bashayer AlDossary and
  • Mariam Almejhim
  • + 3 authors

Non-O1, non-O139 Vibrio cholerae (NOVC) extraintestinal infections are rare, but recently, several clinical incidents have been reported worldwide. Toxigenic V. cholerae is a well-known etiological agent of cholera, responsible for acute dehydrating...

  • Article
  • Open Access
1,174 Views
18 Pages

Phylogeographic Patterns and Genetic Diversity of Anopheles stephensi: Implications for Global Malaria Transmission

  • Jehangir Khan,
  • Dongjing Zhang,
  • Saber Gholizadeh,
  • Yidong Deng,
  • Abdul Aziz,
  • Jianhuang Chen,
  • Pir Tariq Shah,
  • Zhiyue Lv and
  • Tao Chen

Background: Anopheles stephensi, a primary malaria vector in South Asia, is expanding its geographic range, raising concerns about increased malaria transmission. However, critical aspects of its genetic diversity, population structure, and evolution...

  • Article
  • Open Access
1,995 Views
11 Pages

Background: From 2018 to 2021, travel-related extensively drug-resistant (XDR) Salmonella Typhi was identified in Ontario, Canada. Opportunities remain to characterize typhoidal Salmonella antimicrobial susceptibility trends (including multi-drug res...

  • Case Report
  • Open Access
832 Views
7 Pages

Osteomyelitis caused by Moesziomyces aphidis is exceedingly rare and, to our knowledge, has not been previously reported in immunocompetent individuals. This case represents the first documented instance. A 19-year-old woman developed osteomyelitis f...

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Trop. Med. Infect. Dis. - ISSN 2414-6366Creative Common CC BY license