Role of Vaccination on Epidemic Control of the Infectious Diseases and Impact on Public Health

A special issue of Vaccines (ISSN 2076-393X).

Deadline for manuscript submissions: closed (31 December 2024) | Viewed by 2254

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Guest Editor
CNR-IFC Italian National Research Council, Institute of Clinical Physiology, 73100 Lecce, Italy
Interests: epidemiology; public health; vaccination; health promotion
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Guest Editor
Department of Biological and Environmental Sciences and Technologies, University of Salento, 73100 Lecce, Italy
Interests: epidemiology; public health; vaccine-preventable diseases; surveillance

Special Issue Information

Dear Colleagues,

Disease prevention and control are the foundations of public health. In this regard, vaccination serves as a proven, economic, and safe tool to fight against the spread of infectious diseases. 

Vaccine epidemiology makes it possible to determine the strength of infections, efficacy and effectiveness of vaccines, induced immunity, and epidemiological changes. Better knowledge and understanding of the epidemiology of vaccine-preventable diseases, the effects of vaccines, as well as the factors influencing their diffusion and acceptance may help in maintaining public health with important implications for addressing vaccination programs, and designing disease-specific control, elimination and eradication strategies.

In this context, this Special Issue of the journal Vaccines, ‘Role of Vaccination in Controlling Epidemics Caused by Infectious Diseases and its Impact on Public Health’ aims to collate research on the following areas:

  • The spread of vaccine-preventable infectious diseases and the impact of vaccination in reducing infections and disease severity;
  • The effectiveness of prevention programs;
  • The issues of vaccine acceptability and hesitancy, and strategies to increase vaccination coverage rates.

We welcome submissions of original research articles as well as narrative and systematic reviews.

Dr. Antonella Zizza
Prof. Dr. Marcello Guido
Guest Editors

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Keywords

  • vaccine epidemiology
  • efficacy
  • effectiveness
  • acceptability
  • hesitancy
  • epidemic control
  • vaccination strategies

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Published Papers (1 paper)

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Review

20 pages, 1061 KiB  
Review
Foodborne Infections and Salmonella: Current Primary Prevention Tools and Future Perspectives
by Antonella Zizza, Alessandra Fallucca, Marcello Guido, Vincenzo Restivo, Marco Roveta and Cecilia Trucchi
Vaccines 2025, 13(1), 29; https://doi.org/10.3390/vaccines13010029 - 31 Dec 2024
Viewed by 1567
Abstract
Salmonella is considered the major zoonotic and foodborne pathogen responsible for human infections. It includes the serovars causing typhoid fever (S. typhi and S. paratyphi) and the non-typhoidal salmonella (NTS) serovars (S. enteritidis and S. typhimurium), causing enteric infections [...] Read more.
Salmonella is considered the major zoonotic and foodborne pathogen responsible for human infections. It includes the serovars causing typhoid fever (S. typhi and S. paratyphi) and the non-typhoidal salmonella (NTS) serovars (S. enteritidis and S. typhimurium), causing enteric infections known as “Salmonellosis”. NTS represents a major public health burden worldwide. The consumption of S. enteritidis-contaminated animal foods is the main source of this disease in humans, and eradicating bacteria from animals remains a challenge. NTS causes various clinical manifestations, depending on the quantity of bacteria present in the food and the immune status of the infected individual, ranging from localized, self-limiting gastroenteritis to more serious systemic infections. Salmonellosis prevention is based on hygienic and behavioral rules related to food handling that aim to reduce the risk of infection. However, no vaccine against NTS is available for human use. This aspect, in addition to the increase in multidrug-resistant strains and the high morbidity, mortality, and socioeconomic costs of NTS-related diseases, makes the development of new prevention and control strategies urgently needed. The success of the vaccines used to protect against S. typhi encouraged the development of NTS vaccine candidates, including live attenuated, subunit-based, and recombinant-protein-based vaccines. In this review, we discuss the epidemiological burden of Salmonellosis and its primary prevention, focusing on the current status and future perspectives of the vaccines against NTS. Full article
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