Vaccination Analysis in China

A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Vaccines against Infectious Diseases".

Deadline for manuscript submissions: closed (31 October 2023) | Viewed by 1764

Special Issue Editors


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Guest Editor
Disease Control and Prevention Institute/Jinan University-BioKangtai Vaccine Institute, Jinan University, Guangzhou, China
Interests: infectious and chronic disease prevention and control

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Guest Editor
Department of Nutrition, School of Medicine, Jinan University, Guangzhou 510632, China
Interests: nutrition epidemiology; maternal and child health; nutrition and chronic disease; public health; big data for health care

Special Issue Information

Dear Colleagues,

As you are already aware, infectious diseases have been an important factor in population health. In the field of infectious disease prevention and control, no medical strategy has surpassed vaccination in reducing morbidity and mortality. Vaccination is one of the most cost-effective health investments, and is a proven means to control and eliminate infectious diseases, and is estimated to avoid 2 million to 3 million deaths per year. In many developed countries, infectious disease deaths account for only 4% to 8% of the total deaths, mainly due to the widespread use of vaccines. In some developing countries, 30 or even 50 percent of the total deaths still die from infectious diseases. 

At present, COVID-19, hepatitis B, influenza, pneumonia and HPV are the infectious diseases of great concern in China. The COVID-19 pandemic has caused immeasurable losses across the country and around the world, however, the latest Lancet data in 2019, including China (India, Nigeria, Indonesia, Pakistan, China) accounted for 54% of the total global cases, and the burden of Spn pneumonia for children under 5 in China. As we all know, China has the highest burden of HBV infection in the world. Meanwhile, cervical cancer is the second largest female malignancy after ovarian cancer. In order to control these most important infectious diseases, the only way to prevent infection is to develop effective vaccines, and vaccination is also the most economical and efficient method. 

However, right now, only nine vaccines in China have passed the WHO vaccine pre-certification, which is not commensurate with China's national strength and the actual regulatory level. Moreover, in the actual HPV vaccination, the vaccination rate of HPV vaccine among Chinese adolescent women is still relatively low. Influenza vaccines are not included in China's national immunization program, which have gradually increased over the past 15 years, but have only covered about 2 percent of the population. What are the causes of these phenomena, how to deal with these situations, how to refine the evaluation criteria of vaccine efficacy, still need to be further explored. 

To achieve a broader understanding of the current trends in vaccination and the latest scientific research, this journal is published. Based on your extensive knowledge and experience, we invite you to write original reports, original observations, or reviews to highlight (i) the latest research progress in vaccination, (ii) the status and challenges of vaccines in China, and (iii) the future and development of vaccines in China.

Dr. Xiaofeng Liang
Dr. Dan Liu
Guest Editors

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Keywords

  • vaccinations
  • vaccines
  • COVID-19
  • Hepatitis B
  • influenza
  • Pneumonia
  • Human Papillomavirus (HPV)

Published Papers (1 paper)

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20 pages, 6695 KiB  
Systematic Review
HPV Infection Profiles among People Living with HIV and HPV Vaccine Acceptance among Individuals with Different HIV Infection Statuses in China: A Systematic Meta-Analysis
by Defu Yuan, Shanshan Liu, Yangyang Liu, Fei Ouyang, Wei Ai, Lingen Shi, Xiaoyan Liu, Tao Qiu, Bei Wang and Ying Zhou
Vaccines 2023, 11(10), 1614; https://doi.org/10.3390/vaccines11101614 - 19 Oct 2023
Viewed by 1507
Abstract
To understand the HPV infection profiles among Chinese HIV/AIDS patients and the HPV vaccine acceptance among unvaccinated Chinese people with different HIV infection statuses after the HPV vaccine launch in China, this study searched Web of Science, PubMed, Cochrane Library, Embase, Scopus, CNKI, [...] Read more.
To understand the HPV infection profiles among Chinese HIV/AIDS patients and the HPV vaccine acceptance among unvaccinated Chinese people with different HIV infection statuses after the HPV vaccine launch in China, this study searched Web of Science, PubMed, Cochrane Library, Embase, Scopus, CNKI, WANFANG, SinoMed, and VIP databases up to 23 June 2023, according to the registered protocol (CRD42023449913). A total of 58 studies were included. The results showed that the HPV infection rate among Chinese HIV/AIDS patients was 52.54% (95% CI: 42.11–62.86%) and higher in males than in females (74.55% vs. 41.04%); meanwhile, the rate was higher in the anus than in the cervix (69.22% vs. 41.71%). Although there was no statistical difference, the high-risk HPV infection rate (38.98%) was higher than low-risk HPV (23.86%), and single infections were more common (28.84%) than multiple infections (19.23%). HPV vaccine acceptance among the unvaccinated Chinese population was 59.19% (95% CI: 52.50–65.89%), and was slightly higher among HIV-infected rather than non-HIV-infected individuals (67.72% vs. 59.58%). There was a difference in acceptance among respondents from different regions. Although the difference in acceptance rate between males and females was not statistically significant (61.10% vs. 61.18%), MSM had a higher acceptance rate than non-MSM (84.28% vs. 59.05%). HPV infection is prevalent among HIV patients, demonstrating the need to increase the frequency of HPV screening for PLWH. The HPV vaccine acceptance rate is higher than that of non-HIV-infected individuals. Male acceptance is almost the same as female’s, with MSM acceptance higher than non-MSM, suggesting that using MSM, especially MSM in PLWH, as an entry point may be a practical avenue to explore to further expand the scope of HPV vaccination. Full article
(This article belongs to the Special Issue Vaccination Analysis in China)
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