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Vaccines
Special Issues
Children Diseases and Immunizations
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Children Diseases and Immunizations

A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Human Vaccines and Public Health".

Deadline for manuscript submissions: closed (30 November 2021) | Viewed by 14140

Special Issue Editors

Prof. Dr. Gian Luigi Marseglia

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Guest Editor
Pediatric Clinic, Pediatrics Department, Policlinico San Matteo, University of Pavia, Pavia, Italy
Interests: pediatrics; allergology; immunology; pulmonology
Special Issues, Collections and Topics in MDPI journals
Dr. Silvia Salvatore

E-Mail Website
Guest Editor
Pediatric Unit, Hospital “F. Del Ponte”, Department of Medicine and Surgery, University of Insubria, I-21100 Varese, Italy
Interests: pediatrics; gastroenterology; immunology; food allergy; probiotics
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Massimo Agosti

E-Mail Website
Guest Editor
Neonatal and Pediatric Unit, Hospital “F. Del Ponte”, Department of Medicine and Surgery, University of Insubria, 21100 Varese, Italy
Interests: neonates; neonatal care; preterm infants; nutrition; food allergy; microbiota; human milk
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In the last few years, the key role of vaccinations has reemerged as one of the most important determinants of neonatal, infant and child health and, as a consequence, that of other age groups. The prevention of old and new infections still needs to be continuously empowered with appropriate campaigns to properly inform caregivers and health professionals.

A number of vaccines have been recently proposed, and new vaccines are a current matter of research. New data on fragile populations, preterm newborns, and children with chronic diseases, with immune deficiencies, with allergies and on immunosuppressive treatment demonstrate the need for a global and personalized approach. The relevance of starting immunization in pregnant women has also been shown, and new approaches have been proposed. The aim of this issue is to critically update the knowledge on vaccination programs in all pediatric ages and to help clinicians to improve the care of all pediatric populations.

Prof. Dr. Gian Luigi Marseglia
Dr. Silvia Salvatore
Prof. Dr. Massimo Agosti
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • children health
  • pediatrics
  • allergology
  • immunology
  • pulmonology

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Published Papers (3 papers)

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Research

11 pages, 737 KiB  
Article
Comparison of SARS-CoV-2-Specific Antibodies in Human Milk after mRNA-Based COVID-19 Vaccination and Infection
by Hannah G. Juncker, Sien J. Mulleners, Marit J. van Gils, Tom P. L. Bijl, Christianne J. M. de Groot, Dasja Pajkrt, Aniko Korosi, Johannes B. van Goudoever and Britt J. van Keulen
Vaccines 2021, 9(12), 1475; https://doi.org/10.3390/vaccines9121475 - 14 Dec 2021
Cited by 14 | Viewed by 3115
Abstract
SARS-CoV-2-specific antibodies are secreted into human milk of infected or vaccinated lactating women and might provide protection to the breastfed infant against COVID-19. Differences in antibody response after these types of exposure are unknown. In this longitudinal cohort study, we compared the antibody [...] Read more.
SARS-CoV-2-specific antibodies are secreted into human milk of infected or vaccinated lactating women and might provide protection to the breastfed infant against COVID-19. Differences in antibody response after these types of exposure are unknown. In this longitudinal cohort study, we compared the antibody response in human milk following SARS-CoV-2 vaccination or infection. We analyzed 448 human milk samples of 28 lactating women vaccinated with the SARS-CoV-2 vaccine BNT162b2 as well as 82 human milk samples of 18 lactating women with a prior SARS-CoV-2 infection. The levels of SARS-CoV-2-specific IgA in human milk were determined over a period of 70 days both after vaccination and infection. The amount of SARS-CoV-2-specific IgA in human milk was similar after SARS-CoV-2 vaccination and infection. After infection, the variability in IgA levels was higher than after vaccination. Two participants with detectable IgA prior to vaccination were analyzed separately and showed higher IgA levels following vaccination compared to both groups. In conclusion, breastfed infants of mothers who have been vaccinated with the BNT162b2 vaccine receive human milk with similar amounts of SARS-CoV-2-specific antibodies compared to infants of previously infected mothers. Full article
(This article belongs to the Special Issue Children Diseases and Immunizations)
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16 pages, 5279 KiB  
Article
Prevalence and Factors Associated with Parents’ Non-Intention to Vaccinate Their Children and Adolescents against COVID-19 in Latin America and the Caribbean
by Diego Urrunaga-Pastor, Percy Herrera-Añazco, Angela Uyen-Cateriano, Carlos J. Toro-Huamanchumo, Alfonso J. Rodriguez-Morales, Adrian V. Hernandez, Vicente A. Benites-Zapata and Guido Bendezu-Quispe
Vaccines 2021, 9(11), 1303; https://doi.org/10.3390/vaccines9111303 - 9 Nov 2021
Cited by 34 | Viewed by 6715
Abstract
We aimed to estimate the prevalence and factors associated with parents’ non-intention to vaccinate their children and adolescents against COVID-19 in Latin America and the Caribbean (LAC). We performed a secondary analysis using a database generated by the University of Maryland and Facebook [...] Read more.
We aimed to estimate the prevalence and factors associated with parents’ non-intention to vaccinate their children and adolescents against COVID-19 in Latin America and the Caribbean (LAC). We performed a secondary analysis using a database generated by the University of Maryland and Facebook (Facebook, Inc., Menlo Park, CA, USA). We included adult (18 and over) Facebook users residing in LAC who responded to the survey between 20 May 2021 and 14 July 2021. We included sociodemographic characteristics, comorbidities, mental health, economic and food insecurity, compliance with mitigation strategies against COVID-19, and practices related to vaccination against this disease. We estimated the crude (cPR) and adjusted (aPR) prevalence ratios with their respective 95%CI. We analyzed a sample of 227,740 adults from 20 LAC countries. The prevalence of parents’ non-intention to vaccinate their children and adolescents against COVID-19 was 7.8% (n = 15,196). An age above 35 years old, educational level above college, compliance with physical distancing, use of masks, having economic insecurity, having had COVID-19, anxiety symptoms, depressive symptoms, having a chronic condition or two or more comorbidities, and being vaccinated were associated with a lower prevalence of non-intention to vaccinate children and adolescents against COVID-19. Living in a town, a village, or a rural area was associated with a higher prevalence of non-intention to vaccinate children and adolescents against COVID-19. Approximately nine out of ten parents in LAC intended to vaccinate their children and adolescents against COVID-19. Our results allow for understanding parents’ intentions to vaccinate children and adolescents and help promote and develop education strategies for national vaccination plans against COVID-19. Full article
(This article belongs to the Special Issue Children Diseases and Immunizations)
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15 pages, 575 KiB  
Article
Women’s Empowerment and Children’s Complete Vaccination in the Democratic Republic of the Congo: A Cross-Sectional Analysis
by Xinran Lu, Chuchu Fu, Qianyun Wang, Qiwei He, Jiayi Hee, Rie Takesue and Kun Tang
Vaccines 2021, 9(10), 1117; https://doi.org/10.3390/vaccines9101117 - 1 Oct 2021
Cited by 5 | Viewed by 3403
Abstract
(1) Background: The empowerment of women contributes to better child health and wellness. This study aimed to examine the association between women’s empowerment and complete vaccination of children, as recommended in the National Expanded Program on Immunization (EPI) in the Democratic Republic of [...] Read more.
(1) Background: The empowerment of women contributes to better child health and wellness. This study aimed to examine the association between women’s empowerment and complete vaccination of children, as recommended in the National Expanded Program on Immunization (EPI) in the Democratic Republic of the Congo (DRC). (2) Methods: In this cross-sectional study, a principal component analysis (PCA) was conducted on data from the Multiple-Indicator Cluster Survey 6 (MICS-6) to determine the dimensions of women’s empowerment. Logistic regression analysis was used to assess the association between women’s empowerment and complete vaccination of children stratified by household wealth. In total, 3524 women with children aged 12–23 months were included in the study. (3) Results: Women’s empowerment was defined by three dimensions, namely intrinsic agency, enabling resources, and social independence. Children of women with high levels of empowerment had higher odds of complete vaccination, with values of 1.63 (p = 0.002) and 1.59 (p = 0.012) for intrinsic agency and enabling resources of the empowerment, respectively, compared to the children of women with low levels of empowerment; however, social independence failed to be associated with the vaccination status of children. After stratification by household wealth, the OR of complete vaccination was higher in women from middle-income households with high levels of intrinsic agency (OR: 2.35, p = 0.021) compared to women from poor households with high levels of intrinsic agency (OR: 1.92, p = 0.004). (4) Conclusions: Higher levels of women’s empowerment, especially intrinsic agency and enabling resources, were associated with complete vaccination in children in the DRC. Household wealth status influenced the associations. The empowerment of women is crucial in promoting the complete vaccination of children and providing equal access to vaccines. Full article
(This article belongs to the Special Issue Children Diseases and Immunizations)
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