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Viruses publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Genetic and Epigenetic Regulation of Virus–Host Interaction

edited by

Litao Sun

submission deadline 1 Oct 2026 | Viewed by 216 | Submission Open

Keywords: virus– host interaction; epigenetic regulation; genetic variation; antiviral immunity; post-translational modification; RNA virus; viral infection; host defense response

(This special issue belongs to the Section General Virology)

Epigenetic Modifications in Viral Infections 2026

edited by

Matloob Husain

and

Farjana Ahmed

submission deadline 15 Oct 2026 | Viewed by 136 | Submission Open

Keywords: viral pathogenesis; virus–host interaction; epigenetic modifications; acetylation; methylation; proteomics; genomics

(This special issue belongs to the Section General Virology)

Enteric Viruses in Environment and Humans: Identification, Surveillance and Control

edited by

Rita De Cássia Compagnoli Carmona

and Maria Inês Zanoli Sato

submission deadline 30 Oct 2026 | 6 articles | Viewed by 6205 | Submission Open

Keywords: enteric viruses; wastewater-based epidemiology; human-based epidemiology; One Health

(This special issue belongs to the Section Human Virology and Viral Diseases)

Advances in Animal Influenza Virus Research 2026

edited by

Jansen Araujo

submission deadline 30 Oct 2026 | 2 articles | Viewed by 4083 | Submission Open

Keywords: animal influenza viruses; avian influenza virus; H5N1; viral evolution; viral reassortment; zoonotic potential transmission; diagnostics advances; molecular epidemiology and vaccine development

(This special issue belongs to the Section Animal Viruses)

Advances in Endemic and Emerging Viral Diseases in Livestock: 2nd Edition

edited by

Fernando Vicosa Bauermann

and

Mayara Maggioli

submission deadline 30 Oct 2026 | 1 articles | Viewed by 2122 | Submission Open

Keywords: veterinary virology; livestock; ruminants; swine; vaccines

(This special issue belongs to the Section Animal Viruses)

Tick-Borne Viruses 2026

edited by

Pat Nuttall

submission deadline 31 Oct 2026 | 6 articles | Viewed by 6079 | Submission Open

Keywords: tick-borne viruses; vector-borne pathogens; virus– tick– host interactions; saliva-assisted transmission; tick exosomes; tick antiviral mechanisms; virus evolution; surveillance

(This special issue belongs to the Section General Virology)

Influenza and Other Respiratory Viruses: Prevention, Diagnosis, Treatment: 3rd Edition

edited by

Eric Yager

submission deadline 31 Oct 2026 | 4 articles | Viewed by 3465 | Submission Open

Keywords: influenza; adenovirus; coronoavirus; respiratory syncytial virus; rhinovirus; respiratory virus; antiviral strategies; epidemiology; diagnosis; treatment; vaccination; surveillance; vaccine development

(This special issue belongs to the Section Animal Viruses)

New Findings in Animal Biosecurity Related to Viral Diseases

edited by

Claude Saegerman

and Jean-Pierre Vaillancourt

submission deadline 31 Oct 2026 | 2 articles | Viewed by 2026 | Submission Open

Keywords: viruses; animal; biosecurity; evaluation; communication; needs; cost– benefit analysis; behaviour change

(This special issue belongs to the Section Animal Viruses)

Recent Advances in Anti-HCV, Anti-HBV and Anti-Flavivirus Agents, 2nd Edition

edited by

Grigoris Zoidis

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1746 | Submission Open

Keywords: medicinal chemistry of anti-HCV; anti-HBV and anti-flavivirus agents; synthesis; structure activity relationships (SAR); antiviral drug discovery; HBV; HCV; Dengue (DENV); Yellow Fever (YFV); West Nile (WNV); Zika (ZIKV); mechanism of action; drug targets; in silico studies

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Bacteriophages and Biofilms 2026

edited by

Bartłomiej Grygorcewicz

submission deadline 31 Oct 2026 | 2 articles | Viewed by 1704 | Submission Open

Keywords: bacteriophages; phage therapy; biofilms; phage– biofilm interaction; depolymerases; antibiofilm agents; phage engineering; phage resistance; combination therapy; microbial ecology

(This special issue belongs to the Section Bacterial Viruses)

Early ART Initiation: Impacts on Viral Dynamics and Clinical Outcomes

edited by

Alessandra Vergori

Andrea De Vito

and

Vincenzo Malagnino

submission deadline 31 Oct 2026 | 2 articles | Viewed by 1522 | Submission Open

Keywords: early antiretroviral therapy; HIV viral dynamics; immune recovery; viral reservoir; clinical outcomes; HIV transmission

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Molecular Biomarkers for Viral Infection, 2nd Edition

edited by

Paulina Niedźwiedzka-Rystwej

submission deadline 31 Oct 2026 | 1 articles | Viewed by 793 | Submission Open

Keywords: molecular biomarkers; viral infections; metabolism

(This special issue belongs to the Section General Virology)

Interplay Between Influenza Virus and Host Factors, 2nd Edition

edited by

Matloob Husain

submission deadline 31 Oct 2026 | 1 articles | Viewed by 610 | Submission Open

Keywords: influenza virus; host factors; proviral host factors; antiviral host factors; host adaptation; virus entry; virus assembly; virus release; innate antiviral response; interferon-stimulated genes; post-translational protein modifications

(This special issue belongs to the Section Animal Viruses)

Signaling Pathways in Viral Infection and Antiviral Immunity 2026

edited by

Malathi Krishnamurthy

Praveen Manivannan

, Shelby Clark and Barkha Ramnani

submission deadline 31 Oct 2026 | Viewed by 395 | Submission Open

Keywords: innate immune signaling pathways; antiviral signaling; interferon signaling; cytokine induction and inflammation; host– virus interactions; cell death pathways; autophagy; stress response pathways

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

The Development of Universal Influenza Vaccines

edited by

Yao-Qing Chen

and

Lei Deng

submission deadline 31 Oct 2026 | Viewed by 393 | Submission Open

Keywords: universal influenza vaccine; influenza virus; broadly protective immunity; vaccine development; cross-reactive antibodies

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Arbovirus Diagnosis

edited by Lakshmanane Premkumar and Jesse Waggoner

submission deadline 31 Oct 2026 | Viewed by 338 | Submission Open

Keywords: arboviruses; molecular tests; serology; multiplex assays; diagnostic methods; surveillance; high-throughput assays; point-of-care tests

(This special issue belongs to the Section Human Virology and Viral Diseases)

Diagnostics, Antiviral Therapy and Vaccination Against Orthopoxvirus Infections (2nd Edition)

edited by

Sergei N. Shchelkunov

submission deadline 31 Oct 2026 | Viewed by 237 | Submission Open

Keywords: orthopoxvirus; monkeypox; smallpox; vaccinia; antiviral drugs; next-generation vaccines; molecular diagnostics; viral evolution; outbreak

(This special issue belongs to the Section Animal Viruses)

Plant Protection and Resistance to Viruses

edited by

Patrick Materatski

and

Carla Varanda

submission deadline 31 Oct 2026 | Viewed by 233 | Submission Open

Keywords: plant viruses; plant viral diseases; plant protection; plant– virus interactions; host defense mechanisms; RNA interference; virus-induced gene silencing; plant virus detection and epidemiology; host resistance; sustainable disease management; plant– virus– environment interactions

(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)

Whiteflies and Whitefly-Transmitted Viruses

edited by Eui-Joon Kil

submission deadline 31 Oct 2026 | Viewed by 211 | Submission Open

Keywords: whitefly; Bemisia tabaci; whitefly-transmitted viruses; begomovirus; crinivirus; torradovirus; virus– vector interaction; virus transmission; molecular diagnosis; high-throughput sequencing

(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)

2A and 2A-Like Sequences in Viruses: Function, Mechanism and Biotechnological/Biomedical Applications

edited by Martin Ryan and Garry Luke

submission deadline 31 Oct 2026 | Viewed by 196 | Submission Open

Keywords: virus protein biogenesis; ribosome ‘ skipping’ ; protein co-expression; biotechnology; biomedicine

(This special issue belongs to the Section General Virology)

Viruses and Eye Diseases, 2nd Edition

edited by Homayon Ghiasi and

Deepak Shukla

submission deadline 31 Oct 2026 | Viewed by 151 | Submission Open

Keywords: ocular health; herpesviruses; herpes simplex virus (HSV); varicella zoster virus (VZV); adenovirus; respiratory viruses; Zika virus; cytomegalovirus (CMV); virus– ocular tissue interactions

(This special issue belongs to the Section Human Virology and Viral Diseases)

Preparation for the Next Potential Pandemic—Chikungunya, Dengue, Zika and Other Viruses 2026

edited by

Zoltan Vajo

submission deadline 31 Oct 2026 | Viewed by 147 | Submission Open

Keywords: chikungunya; dengue; zika; next pandemic; epidemiology; pharmaceutics; immunology

(This special issue belongs to the Section Human Virology and Viral Diseases)

Molecular Epidemiology, Evolution, and Transmission of Avian Influenza Viruses: 2nd Edition

edited by

Sasan Fereidouni

submission deadline 31 Oct 2026 | Viewed by 129 | Submission Open

Keywords: avian influenza viruses; highly pathogenic avian influenza viruses (HPAIs); molecular epidemiology; phylogeny; evolution; intra- and cross-species transmission

(This special issue belongs to the Section Animal Viruses)

Plant Virome

edited by

Humberto Debat

submission deadline 31 Oct 2026 | Viewed by 129 | Submission Open

Keywords: plant virology; host– virus interactions; viral ecology; virome evolution; molecular plant pathology

(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)

70 Years of Rhinoviruses: From the Common Cold to Complex Pathogens

edited by

Katarzyna Niespodziana

submission deadline 31 Oct 2026 | Viewed by 124 | Submission Open

Keywords: rhinovirus (RV); asthma; COPD; airway; infection; immunity; diversity; therapy; vaccine; history

(This special issue belongs to the Section Human Virology and Viral Diseases)

Hantaviruses and Their Hosts

edited by Hiroaki Kariwa and

Kumiko Yoshimatsu

submission deadline 31 Oct 2026 | Viewed by 21 | Submission Open

Keywords: hantavirus; hosts; rodents; shrews; bats; moles; virus– host interaction

(This special issue belongs to the Section Animal Viruses)

Neurocognitive Dynamics and Biomarkers in HIV

edited by Mattia Trunfio and Carmela Pinnetti

submission deadline 1 Nov 2026 | 2 articles | Viewed by 3618 | Submission Open

Keywords: HIV infection; neurodegeneration; biomarkers; neuroinflammation; cognitive performance; mood; central nervous system

(This special issue belongs to the Section Human Virology and Viral Diseases)

Bovine Viral Diarrhea Viruses and Other Pestiviruses

edited by

Enrica Sozzi

submission deadline 30 Nov 2026 | 12 articles | Viewed by 15612 | Submission Open

Keywords: epidemiological survey; prevalence; seroprevalence; bovine viral diarrhoea; mucosal disease; neutralizing antibodies; taxonomy; antiviral drugs; vaccines; species and subgenotypes; wild animal

(This special issue belongs to the Section Animal Viruses)

HPV-Associated Cancers 2026

edited by Diane M. Harper

submission deadline 30 Nov 2026 | 2 articles | Viewed by 5040 | Submission Open

Keywords: HPV; cervical cancer; head and neck cancer; penile cancer; cancer prevention; targeted therapy; cancer stem cells; molecular study; carcinogenesis; immunotherapy

(This special issue belongs to the Section Human Virology and Viral Diseases)

Cellular Immune Response to Hepatitis Viruses

edited by

Armando Andres Roca Suarez

submission deadline 30 Nov 2026 | 2 articles | Viewed by 4978 | Submission Open

Keywords: viral hepatitis; viral/host interactions; immune response; immune evasion; immunopathogenesis; immunomodulatory therapy; pre-clinical models

(This special issue belongs to the Section Human Virology and Viral Diseases)

Virus Biosensing

edited by Guobin Mao

submission deadline 30 Nov 2026 | 2 articles | Viewed by 3054 | Submission Open

Keywords: virus detection; molecular diagnosis; immunoassay; nucleic acid amplification; CRISPR-based detection; nucleic acid assembly; biosensor; point-of-care testing

(This special issue belongs to the Section General Virology)

Advances in Rabies Research 2025–2026

edited by Juan A. Montaño-Hirose and

Charles E. Rupprecht

submission deadline 30 Nov 2026 | Viewed by 1592 | Submission Open

Keywords: rabies; zoonosis; vaccine; evolution; structural biology; viral replication; virus– host interaction; pathogenesis and immunity; clinical virology

(This special issue belongs to the Section General Virology)

Epidemiology, Risk Analysis, Detection and Management of Lumpy Skin Disease in Europe

edited by

Claude Saegerman

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1475 | Submission Open

Keywords: lumpy skin disease (LSD); lumpy skin disease virus (LSDV); vectors; pathogenesis; epidemiology; modelling; risk analysis; detection; management; cost– benefit analysis; Europe

(This special issue belongs to the Section Animal Viruses)

Natural, Semisynthetic, and Synthetic Antiviral Drugs: Combating Emerging and Re-Emerging Viral Threats

edited by

Otávio Augusto Chaves

and

Carlos Serpa

submission deadline 30 Nov 2026 | Viewed by 132 | Submission Open

Keywords: novel antiviral agents and therapeutic strategies; antivirals design and discovery; natural products screening; natural products as a scaffold for semisynthetic antivirals; repurposing drugs; high-throughput screening; antiviral resistance; biophysical characterization of antiviral– target interactions; combination of light and photosensitizers in antiviral discovery; cell-based and in vivo assays; mechanisms of antiviral action; In silico antiviral predictions; molecular docking and dynamics simulations

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Human Metapneumovirus (HMPV)

edited by Julia Dubois and Guy Boivin

submission deadline 30 Nov 2026 | Viewed by 107 | Submission Open

Keywords: human metapneumovirus (HMPV); respiratory syncytial virus (RSV); Pneumoviridae; viral pathogenesis; epidemiology and clinical burden; host immune response; antiviral therapy; vaccine development

(This special issue belongs to the Section Human Virology and Viral Diseases)

Phage Assembly

edited by

Andreas Kuhn

and

Julie Thomas

submission deadline 30 Nov 2026 | Viewed by 95 | Submission Open

Keywords: capsid assembly; DNA packaging; portal assembly; host receptor; tail contraction; ejectosome assembly; DNA translocation; lysis control

(This special issue belongs to the Section Bacterial Viruses)

Research on the Zoonotic Pathogen: Lassa Virus and Lassa Fever

edited by

Umaru Bangura

submission deadline 30 Nov 2026 | Viewed by 2 | Submission Open

Keywords: Lassa-virus; zoonotic; Mastomys natalensis; West-Africa; epidemiology; genomes; ecology; surveillance; emerging-infection; transmission

(This special issue belongs to the Section Human Virology and Viral Diseases)

Respiratory Viral Pathogenesis and Host-Microbe Crosstalk: From Bench to Bedside

edited by Shenghai Huang and

Theo J. Moraes

submission deadline 1 Dec 2026 | 4 articles | Viewed by 3802 | Submission Open

Keywords: respiratory viruses; pathogenesis; host– microbe crosstalk; etiological diagnosis; prevention and treatment; RSV; influenza; coronavirus

(This special issue belongs to the Section Human Virology and Viral Diseases)

Viral Surveillance, Transmission, Pathogenesis, and Vaccine Development in Domestic Animals and Wildlife

edited by

Jieshi Yu

Feng Li

and Wen-Kang Wei

submission deadline 1 Dec 2026 | 2 articles | Viewed by 2098 | Submission Open

Keywords: animal viruses; influenza viruses; coronaviruses; rotaviruses; transmission; epidemiology; surveillance; pathogenesis; one health; vaccine; domestic animals; wildlife; emerging viruses; re-emerging viruses

(This special issue belongs to the Section Animal Viruses)

Molecular and Cellular Biology of Human Oncogenic Viruses: 2nd Edition

edited by

Roberta Gonnella

submission deadline 1 Dec 2026 | 1 articles | Viewed by 1310 | Submission Open

Keywords: oncoviruses; antiviral drugs; viral oncogenesis; viral infection; oncogenic pathways; epigenetics

(This special issue belongs to the Section Human Virology and Viral Diseases)

Human and Animal Papillomavirus: Infections, Genetics, and Vaccines (2nd Edition)

edited by

Antonio Carlos de Freitas

and

Anna Silva

submission deadline 10 Dec 2026 | 1 articles | Viewed by 1332 | Submission Open

Keywords: papillomavirus (PV); vaccines; infection biology; genetics; HPV and nongenital cancer; molecular epidemiology; bioinformatics; oncogenesis; HPV and cancer; animal papillomavirus and associated diseases

(This special issue belongs to the Section Human Virology and Viral Diseases)

Functional RNAs in Virology

edited by

Michael T. Wolfinger

submission deadline 15 Dec 2026 | 1 articles | Viewed by 887 | Submission Open

Keywords: functional RNA elements; viral RNA structure; cis-acting RNA motifs; non-coding RNAs; RNA– protein interactions; RNA-based regulation; RNA virus biology; structured RNA; computational RNA analysis; virus bioinformatics

(This special issue belongs to the Section General Virology)

The Ebola Legacy: Five Decades of Virological Breakthroughs

edited by

Gaya K. Amarasinghe

, Daisy W. Leung and

Christopher F. Basler

submission deadline 15 Dec 2026 | Viewed by 148 | Submission Open

Keywords: Ebola virus; viral pathogenesis; molecular virology; antivirals; therapeutics; diagnostics

(This special issue belongs to the Section Human Virology and Viral Diseases)

Bioinformatics and Computational Approaches in Viral Genomics and Evolution 2025–2026

edited by Camila Malta Romano, Mariana Severo Ramundo and Nilson Coimbra

submission deadline 16 Dec 2026 | 7 articles | Viewed by 9661 | Submission Open

Keywords: bioinformatics tools; genomic surveillance; viral evolution; computational genomics; host-pathogen interactions

(This special issue belongs to the Section General Virology)

Mechanisms of Ribozyviria Transmission in Animal and Vegetal Holobionts

edited by

Maurizia Rossana Brunetto

and Ferruccio Bonino

submission deadline 18 Dec 2026 | Viewed by 496 | Submission Open

Keywords: viroid-like RNAs; holobionts; RNA viruses; circular RNA genomes; satellite viruses; HBsAg (hepatitis b surface antigen)

(This special issue belongs to the Section General Virology)

Virology in Italy 2026—10th National Congress of the Italian Society for Virology

edited by

Enzo Tramontano

Guido Antonelli

Francesca Caccuri

, Massimo Turina and

Gabriele Vaccari

submission deadline 20 Dec 2026 | Viewed by 19 | Submission Open

Keywords: Italy; emerging viruses; viral subversion of host cell processes; viruses of microbes; antivirals; vaccines; emerging methods in virology; RNA in virus infection; plant viruses; antiviral innate immunity; animal viruses; mycoviruses

(This special issue belongs to the Section General Virology)

Advances in Respiratory Viruses Research: From Basic Studies to Public Health

edited by Anna Puigdellívol-Sánchez

submission deadline 30 Dec 2026 | 1 articles | Viewed by 881 | Submission Open

Keywords: respiratory viruses; SARS-CoV-2 co-variants; virus-host interaction; genetic susceptibility; host genetic factors; immune response; wastewater surveillance; seasonal vaccines; differential diagnosis; long COVID; COVID-19 sequelae

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Tiny Giants, Hidden Genes: Genomic Innovation in Nucleocytoviricota

edited by Paulo Victor de Miranda Boratto and Talita Melo Hanchuk

submission deadline 30 Dec 2026 | Viewed by 197 | Submission Open

Keywords: nucleocytoviricota; giant DNA viruses; genetic dark matter; viral genomics; viral evolution; virus– host interactions; viral metabolism

(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)

Advances in Research on Emerging and Zoonotic Diseases

edited by Vladimir Stevanović and

Tatjana Vilibic-Cavlek

submission deadline 30 Dec 2026 | Viewed by 196 | Submission Open

Keywords: emerging infectious diseases; zoonoses; epidemiology; pathogenesis; diagnostics

(This special issue belongs to the Section Animal Viruses)

BSL4 Viruses: Understanding and Controlling Highly Infectious Pathogens, 2nd Edition

edited by Courtney B. Woolsey

submission deadline 30 Dec 2026 | Viewed by 184 | Submission Open

Keywords: virus– host; viral life cycle; viral replication; pathogenesis; epidemiology; medical countermeasures; antivirals; Ebola virus; Marburg virus; Lassa virus; Nipah virus; Hendra virus; Crimean– Congo hemorrhagic fever virus; arenaviruses; paramyxoviruses; Nairo viruses; filoviruses; hemorrhagic fever virus

(This special issue belongs to the Section Animal Viruses)

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