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Conservation and Diversification of tRNA t6A-Modifying Enzymes across the Three Domains of Life

  • Chenchen Su,
  • Mengqi Jin and
  • Wenhua Zhang
Int. J. Mol. Sci.2022, 23(21), 13600;https://doi.org/10.3390/ijms232113600

6 November 2022

The universal N6-threonylcarbamoyladenosine (t6A) modification occurs at position 37 of tRNAs that decipher codons starting with adenosine. Mechanistically, t6A stabilizes structural configurations of the anticodon stem loop, promotes anticodon&ndash...

(This article belongs to the Special Issue RNA-Binding Proteins — Structure, Function, Networks and Diseases)
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