Search Results (5)

This paper designs and implements an energy management system based on the Spring Boot framework. The system mainly includes three layers, which are the data collection layer, the business logic layer, and the display interface layer from bottom to top. The data collection layer is based on the RS-485 electrical standard and the MODBUS communication protocol. The two protocols connect all energy consumption monitoring points into a mixed topology communication network in the enterprise. The programs in the data collection layer poll each energy consumption monitoring point in the network to collect the data and transmit to the business logic layer. The business logic layer is developed on the basis of the Spring Boot framework and mainly includes two parts: the MySQL database and Tomcat server. In the MySQL database, the stored data are horizontally split according to the time column and stored in different data tables. The split of data reduces the load of a single data table and improves the query performance of the database. The Tomcat server is built into the Spring Boot framework to provide a basic environment for system operation. The Spring Boot framework is the core component of the system. It is responsible for collecting, storing, and analyzing data from energy consumption monitoring points, receiving and processing data requests from the display interface layer. It also provides standard data interfaces to the external programs. The display interface layer is developed on the basis of the Vue framework and integrated into the Spring Boot framework. The display layer combines an open-source visualization chart library called ECharts to provide users with a fully functional and friendly human–computer interaction interface. Through the calculation of hardware and software costs, considering the personnel cost in different regions, the total cost of the energy management system can be estimated. The cost of construction was approximately 210,000 USD in this paper. Since the system was actually deployed in a manufacturing company in December 2019, it has been operating stably for more than 600 days. Full article

In systems biology, biological phenomena are often modeled by Ordinary Differential Equations (ODEs) and distributed in the de facto standard file format SBML. The primary analyses performed with such models are dynamic simulation, steady-state analysis, and parameter estimation. These methodologies are mathematically formalized, and libraries for such analyses have been published. Several tools exist to create, simulate, or visualize models encoded in SBML. However, setting up and establishing analysis environments is a crucial hurdle for non-modelers. Therefore, easy access to perform fundamental analyses of ODE models is a significant challenge. We developed SBMLWebApp, a web-based service to execute SBML-based simulation, steady-state analysis, and parameter estimation directly in the browser without the need for any setup or prior knowledge to address this issue. SBMLWebApp visualizes the result and numerical table of each analysis and provides a download of the results. SBMLWebApp allows users to select and analyze SBML models directly from the BioModels Database. Taken together, SBMLWebApp provides barrier-free access to an SBML analysis environment for simulation, steady-state analysis, and parameter estimation for SBML models. SBMLWebApp is implemented in Java™ based on an Apache Tomcat^® web server using COPASI, the Systems Biology Simulation Core Library (SBSCL), and LibSBMLSim as simulation engines. SBMLWebApp is licensed under MIT with source code freely available. At the end of this article, the Data Availability Statement gives the internet links to the two websites to find the source code and run the program online. Full article

(1) Motivation: The exponential increase in multilayered data, including omics, pathways, chemicals, and experimental models, requires innovative strategies to identify new linkages between drug response information and omics features. Despite the availability of databases such as the Cancer Cell Line Encyclopedia (CCLE), the Cancer Therapeutics Response Portal (CTRP), and The Cancer Genome Atlas (TCGA), it is still challenging for biologists to explore the relationship between drug response and underlying genomic features due to the heterogeneity of the data. In light of this, the Integrated Pharmacogenomic Database of Cancer Cell Lines and Tissues (IPCT) has been developed as a user-friendly way to identify new linkages between drug responses and genomic features, as these findings can lead not only to new biological discoveries but also to new clinical trials. (2) Results: The IPCT allows biologists to compare the genomic features of sensitive cell lines or small molecules with the genomic features of tumor tissues by integrating the CTRP and CCLE databases with the REACTOME, cBioPortal, and Expression Atlas databases. The input consists of a list of small molecules, cell lines, or genes, and the output is a graph containing data entities connected with the queried input. Users can apply filters to the databases, pathways, and genes as well as select computed sensitivity values and mutation frequency scores to generate a relevant graph. Different objects are differentiated based on the background color of the nodes. Moreover, when multiple small molecules, cell lines, or genes are input, users can see their shared connections to explore the data entities common between them. Finally, users can view the resulting graphs in the online interface or download them in multiple image or graph formats. (3) Availability and Implementation: The IPCT is available as a web application with an integrated MySQL database. The web application was developed using Java and deployed on the Tomcat server. The user interface was developed using HTML5, JQuery v.3.1.0, and the Cytoscape Graph API v.1.0.4. The IPCT web and the source code are available in Sample Availability section. Full article

In view of rock burst accidents frequently occurring, a basic framework for an intelligent early warning system for rock bursts (IEWSRB) is constructed based on several big data technologies in the computer industry, including data mining, databases and data warehouses. Then, a data warehouse is modeled with regard to monitoring the data of rock bursts, and the effective application of data mining technology in this system is discussed in detail. Furthermore, we focus on the K-means clustering algorithm, and a data visualization interface based on the Browser/Server (B/S) mode is developed, which is mainly based on the Java language, supplemented by Cascading Style Sheets (CSS), JavaScript and HyperText Markup Language (HTML), with Tomcat, as the server and Mysql as the JavaWeb project of the rock burst monitoring data warehouse. The application of data mining technology in IEWSRB can improve the existing rock burst monitoring system and enhance the prediction. It can also realize real-time queries and the analysis of monitoring data through browsers, which is very convenient. Hence, it can make important contributions to the safe and efficient production of coal mines and the sustainable development of the coal economy. Full article

Increasing costs of diagnostic healthcare have necessitated the development of hardware independent non-invasive Point of Care (POC) systems. Although anemia prevalence rates in global populations vary between 10% and 60% in various demographic groups, smart monitoring systems have not yet been developed for screening and tracking anemia-like pallor. In this work, we present two cloud platform-hosted POC applications that are directed towards smart monitoring of anemia-like pallor through eye and tongue pallor site images. The applications consist of a front-end graphical user interface (GUI) module and two different back-end image processing and machine learning modules. Both applications are hosted on a browser accessible tomcat server ported to an Azure Virtual Machine (VM). We observe that the first application spatially segments regions of interest from pallor site images with higher pallor classification accuracy and relatively longer processing times when compared to the lesser accurate yet faster second application. Also, both applications achieve 65%–98% accuracy in separating normal images from images with pallor or abnormalities. The optimized front-end module is significantly light-weight with a run-through time ratio of 10−5 with respect to the back-end modules. Thus, the proposed applications are portable and hardware independent, allowing for their use in pallor monitoring and screening tasks. Full article