Search Results (29)

Traditional sleep staging studies typically rely on signals collected using contact-based sensors, which may interfere with the natural sleep state of subjects and thus affect the authenticity and reliability of the recorded data. To address this limitation, this study proposes an automatic sleep staging method based on non-contact single-channel ballistocardiogram (BCG) signals. First, band-pass filtering is applied to the raw BCG signals to separate the heart rate and respiratory components. Heart rate variability (HRV) and respiratory rate variability (RRV) features are then extracted, and mutual information is used to select key feature subsets that exhibit strong correlations with different sleep stages. Considering the complexity and prominent temporal characteristics of real-world sleep data, a temporal modeling network named TLA-SleepNet is constructed to enhance the model’s capability in capturing complex sequential features and improving robustness. Experiments conducted on 10 independent sleep recordings containing a total of 10,614 sleep epochs demonstrate that, under subject non-independent testing conditions with five-fold cross-validation, the proposed method achieves an accuracy of 87.1% in the sleep staging task, with precision, kappa coefficient, and F1-score reaching 92.4%, 81.9%, and 88.7%, respectively. The results indicate that the proposed method can achieve a reliable sleep staging performance without direct contact between sensors and the human body, providing a feasible solution for non-contact sleep monitoring in home-based and mobile healthcare applications. Full article

Simultaneous Electroencephalography (EEG) and functional Magnetic Resonance Imaging (fMRI) provide a powerful framework for investigating brain dynamics; however, ballistocardiogram (BCG) artifacts in EEG compromise signal quality and limit the assessment of brain connectivity. This study evaluated three widely used artifact removal methods—Average Artifact Subtraction (AAS), Optimal Basis Set (OBS), and Independent Component Analysis (ICA)—together with two hybrid approaches (AAS + ICA and OBS + ICA). Unlike previous studies that focused solely on signal-level metrics, we adopted a holistic framework that combined signal quality indicators with graph-theoretical analysis of EEG-fMRI connectivity in static and dynamic contexts. The results show that AAS provides the best signal quality, whereas OBS better preserves structural similarity. ICA, although weaker in terms of signal metrics, demonstrates sensitivity to frequency-specific patterns in dynamic graphs. Hybrid methods yield benefits, with OBS + ICA producing the lowest p-values across frequency band pairs (e.g., theta–beta and delta–gamma), particularly in dynamic graphs. Topological analyses revealed that artifact removal significantly affected network structure, with dynamic analyses showing more pronounced frequency-specific effects than static analyses. High-frequency bands, such as beta and gamma, exhibit stronger differentiation under dynamic conditions. Overall, this study offers new insights into the relationship between artifact removal and brain network integrity, emphasizing the need for multimodal and frequency-sensitive evaluation strategies. The findings guide preprocessing decisions in EEG-fMRI studies and clarify how methodological choices shape the interpretation of brain connectivity. Full article

This study proposes a novel heart rate estimation method that detects subtle cardiac-induced vibrations propagated through the cardiovascular system based on the ballistocardiography (BCG) principle, using a six-axis heart rate sensing device that integrates a three-axis accelerometer and a three-axis gyroscope. To validate the effectiveness of the proposed method, a comparative analysis was conducted against heart rate measurements obtained from photoplethysmography (PPG) sensors, which are widely used in conventional heart rate monitoring. Experiments were conducted on 20 adult participants, and frequency domain analysis was performed using different time windows of 30 s, 20 s, 8 s, and 4 s. The results showed that the 4 s window provided the highest accuracy in heart rate estimation, demonstrating that the proposed method can effectively capture fine cardiac-induced vibrations. This approach offers a significant advantage by utilizing inertial sensors commonly embedded in wearable devices for heart rate monitoring without the need for additional optical sensors. Compared to optical-based systems, the proposed method is more power-efficient and less affected by environmental factors such as ambient lighting conditions. The findings suggest that heart rate estimation using the six-axis heart rate sensing device presents a reliable, continuous, and non-invasive alternative for cardiovascular monitoring. Full article

Blood pressure (BP) measurement is a major physiological information for people with cardiovascular diseases, such as hypertension, heart failure, and atherosclerosis. Moreover, elders and patients with kidney disease and diabetes mellitus also are suggested to measure their BP every day. The cuffless BP measurement has been developed in the past 10 years, which is comfortable to users. Now, ballistocardiogram (BCG) and impedance plethysmogram (IPG) could be used to perform the cuffless BP measurement. Thus, the aim of this study is to realize edge computing for the BP measurement in real time, which includes measurements of BCG and IPG signals, digital signal process, feature extraction, and BP estimation by machine learning algorithm. This system measured BCG and IPG signals from a bodily weight-fat scale with the self-made circuits. The signals were filtered to reduce the noise and segmented by 2 s. Then, we proposed a flowchart to extract the parameter, pulse transit time (PTT), within each segment. The feature included two calibration-based parameters and one calibration-free parameter was used to estimate BP with XGBoost. In order to realize the system in STM32F756ZG NUCLEO development board, we limited the hyperparameters of XGBoost model, including maximum depth (max_depth) and tree number (n_estimators). Results show that the error of systolic blood pressure (SBP) and diastolic blood pressure (DBP) in server-based computing are 2.64 ± 9.71 mmHg and 1.52 ± 6.32 mmHg, and in edge computing are 2.2 ± 10.9 mmHg and 1.87 ± 6.79 mmHg. This proposed method significantly enhances the feasibility of bodily weight-fat scale in the BP measurement for effective utilization in mobile health applications. Full article

This paper describes a signal quality classification method for arm ballistocardiogram (BCG), which has the potential for non-invasive and continuous blood pressure measurement. An advantage of the BCG signal for wearable devices is that it can easily be measured using accelerometers. However, the BCG signal is also susceptible to noise caused by motion artifacts. This distortion leads to errors in blood pressure estimation, thereby lowering the performance of blood pressure measurement based on BCG. In this study, to prevent such performance degradation, a binary classification model was created to distinguish between high-quality versus low-quality BCG signals. To estimate the most accurate model, four time-series imaging methods (recurrence plot, the Gramain angular summation field, the Gramain angular difference field, and the Markov transition field) were studied to convert the temporal BCG signal associated with each heartbeat into a 448 × 448 pixel image, and the image was classified using CNN models such as ResNet, SqueezeNet, DenseNet, and LeNet. A total of 9626 BCG beats were used for training, validation, and testing. The experimental results showed that the ResNet and SqueezeNet models with the Gramain angular difference field method achieved a binary classification accuracy of up to 87.5%. Full article

Techniques for noninvasively acquiring the vital information of infants and young children are considered very useful in the fields of healthcare and medical care. An unobstructive measurement method for sleeping infants and young children under the age of 6 years using a sheet-type vital sensor with a polyvinylidene fluoride (PVDF) pressure-sensitive layer is demonstrated. The signal filter conditions to obtain the ballistocardiogram (BCG) and phonocardiogram (PCG) are discussed from the waveform data of infants and young children. The difference in signal processing conditions was caused by the physique of the infants and young children. The peak-to-peak interval (PPI) extracted from the BCG or PCG during sleep showed an extremely high correlation with the R-to-R interval (RRI) extracted from the electrocardiogram (ECG). The vital changes until awakening in infants monitored using a sheet sensor were also investigated. In infants under one year of age that awakened spontaneously, the distinctive vital changes during awakening were observed. Understanding the changes in the heartbeat and respiration signs of infants and young children during sleep is essential for improving the accuracy of abnormality detection by unobstructive sensors. Full article

A mattress-type non-influencing sleep apnea monitoring system was designed to detect sleep apnea-hypopnea syndrome (SAHS). The pressure signals generated during sleep on the mattress were collected, and ballistocardiogram (BCG) and respiratory signals were extracted from the original signals. In the experiment, wavelet transform (WT) was used to reduce noise and decompose and reconstruct the signal to eliminate the influence of interference noise, which can directly and accurately separate the BCG signal and respiratory signal. In feature extraction, based on the five features commonly used in SAHS, an innovative respiratory waveform similarity feature was proposed in this work for the first time. In the SAHS detection, the binomial logistic regression was used to determine the sleep apnea symptoms in the signal segment. Simulation and experimental results showed that the device, algorithm, and system designed in this work were effective methods to detect, diagnose, and assist the diagnosis of SAHS. Full article

We introduce a new electroencephalogram (EEG) net, which will allow clinicians to monitor EEG while tracking head motion. Motion during MRI limits patient scans, especially of children with epilepsy. EEG is also severely affected by motion-induced noise, predominantly ballistocardiogram (BCG) noise due to the heartbeat. Methods: The MotoNet was built using polymer thick film (PTF) EEG leads and motion sensors on opposite sides in the same flex circuit. EEG/motion measurements were made with a standard commercial EEG acquisition system in a 3 Tesla (T) MRI. A Kalman filtering-based BCG correction tool was used to clean the EEG in healthy volunteers. Results: MRI safety studies in 3 T confirmed the maximum heating below 1 °C. Using an MRI sequence with spatial localization gradients only, the position of the head was linearly correlated with the average motion sensor output. Kalman filtering was shown to reduce the BCG noise and recover artifact-clean EEG. Conclusions: The MotoNet is an innovative EEG net design that co-locates 32 EEG electrodes with 32 motion sensors to improve both EEG and MRI signal quality. In combination with custom gradients, the position of the net can, in principle, be determined. In addition, the motion sensors can help reduce BCG noise. Full article

Heart rate variability (HRV) features support several clinical applications, including sleep staging, and ballistocardiograms (BCGs) can be used to unobtrusively estimate these features. Electrocardiography is the traditional clinical standard for HRV estimation, but BCGs and electrocardiograms (ECGs) yield different estimates for heartbeat intervals (HBIs), leading to differences in calculated HRV parameters. This study examines the viability of using BCG-based HRV features for sleep staging by quantifying the impact of these timing differences on the resulting parameters of interest. We introduced a range of synthetic time offsets to simulate the differences between BCG- and ECG-based heartbeat intervals, and the resulting HRV features are used to perform sleep staging. Subsequently, we draw a relationship between the mean absolute error in HBIs and the resulting sleep-staging performances. We also extend our previous work in heartbeat interval identification algorithms to demonstrate that our simulated timing jitters are close representatives of errors between heartbeat interval measurements. This work indicates that BCG-based sleep staging can produce accuracies comparable to ECG-based techniques such that at an HBI error range of up to 60 ms, the sleep-scoring error could increase from 17% to 25% based on one of the scenarios we examined. Full article

Electronic health (eHealth) is a strategy to improve the physical and mental condition of a human, collecting daily physiological data and information from digital apparatuses. Body weight and blood pressure (BP) are the most popular and important physiological data. The goal of this study is to develop a minimal contact BP measurement method based on a commercial body weight-fat scale, capturing biometrics when users stand on it. The pulse transit time (PTT) is extracted from the ballistocardiogram (BCG) and impedance plethysmogram (IPG), measured by four strain gauges and four footpads of a commercial body weight-fat scale. Cuffless BP measurement using the electrocardiogram (ECG) and photoplethysmogram (PPG) serves as the reference method. The BP measured by a commercial BP monitor is considered the ground truth. Twenty subjects participated in this study. By the proposed model, the root-mean-square errors and correlation coefficients (r²s) of estimated systolic blood pressure and diastolic blood pressure are 7.3 ± 2.1 mmHg and 4.5 ± 1.8 mmHg, and 0.570 ± 0.205 and 0.284 ± 0.166, respectively. This accuracy level achieves the C grade of the corresponding IEEE standard. Thus, the proposed method has the potential benefit for eHealth monitoring in daily application. Full article

Atrial fibrillation (AF) is the most common arrhythmia and can seriously threaten patient health. Research on AF detection carries important clinical significance. This manuscript proposes an AF detection method based on ballistocardiogram (BCG) signals collected by a noncontact sensor. We first constructed a BCG signal dataset consisting of 28,214 ten-second nonoverlapping segments collected from 45 inpatients during overnight sleep, including 9438 for AF, 9570 for sinus rhythm (SR), and 9206 for motion artifacts (MA). Then, we designed a residual convolutional neural network (CNN) for AF detection. The network has four modules, namely a downsampling convolutional module, a local feature learning module, a global feature learning module, and a classification module, and it extracts local and global features from BCG signals for AF detection. The model achieved precision, sensitivity, specificity, F1 score, and accuracy of 96.8%, 93.7%, 98.4%, 95.2%, and 96.8%, respectively. The results indicate that the AF detection method proposed in this manuscript could serve as a basis for long-term screening of AF at home based on BCG signal acquisition. Full article

Atrial fibrillation (AF) is the most common clinically significant arrhythmia; therefore, AF detection is crucial. Here, we propose a novel feature extraction method to improve AF detection performance using a ballistocardiogram (BCG), which is a weak vibration signal on the body surface transmitted by the cardiogenic force. In this paper, continuous time windows (CTWs) are added to each BCG segment and recurrence quantification analysis (RQA) features are extracted from each time window. Then, the number of CTWs is discussed and the combined features from multiple time windows are ranked, which finally constitute the CTW–RQA features. As validation, the CTW–RQA features are extracted from 4000 BCG segments of 59 subjects, which are compared with classical time and time-frequency features and up-to-date energy features. The accuracy of the proposed feature is superior, and three types of features are fused to obtain the highest accuracy of 95.63%. To evaluate the importance of the proposed feature, the fusion features are ranked using a chi-square test. CTW–RQA features account for 60% of the first 10 fusion features and 65% of the first 17 fusion features. It follows that the proposed CTW–RQA features effectively supplement the existing BCG features for AF detection. Full article

Currently, in terms of reducing the infection risk of the COVID-19 virus spreading all over the world, the development of touchless blood pressure (BP) measurement has potential benefits. The pulse transit time (PTT) has a high relation with BP, which can be measured by electrocardiogram (ECG) and photoplethysmogram (PPG). The ballistocardiogram (BCG) reflects the mechanical vibration (or displacement) caused by the heart contraction/relaxation (or heart beating), which can be measured from multiple degrees of the body. The goal of this study is to develop a cuffless and touchless BP-measurement method based on a commercial weight scale combined with a PPG sensor when measuring body weight. The proposed method was that the PTT_BCG-PPGT was extracted from the BCG signal measured by a weight scale, and the PPG signal was measured from the PPG probe placed at the toe. Four PTT models were used to estimate BP. The reference method was the PTT_ECG-PPGF extracted from the ECG signal and PPG signal measured from the PPG probe placed at the finger. The standard BP was measured by an electronic blood pressure monitor. Twenty subjects were recruited in this study. By the proposed method, the root-mean-square error (E_RMS) of estimated systolic blood pressure (SBP) and diastolic blood pressure (DBP) are 6.7 ± 1.60 mmHg and 4.8 ± 1.47 mmHg, respectively. The correlation coefficients, r², of the proposed model for the SBP and DBP are 0.606 ± 0.142 and 0.284 ± 0.166, respectively. The results show that the proposed method can serve for cuffless and touchless BP measurement. Full article

Flexible sensor arrays are widely used for wearable physiological signal recording applications. A high density sensor array requires the signal readout to be compatible with multiple channels. This paper presents a highly-integrated remote health monitoring system integrating a flexible pressure sensor array with a multi-channel wireless readout chip. The custom-designed chip features 64 voltage readout channels, a power management unit, and a wireless transceiver. The whole chip fabricated in a 65 nm complementary metal-oxide-semiconductor (CMOS) process occupies 3.7 × 3.7 mm², and the core blocks consume 2.3 mW from a 1 V supply in the wireless recording mode. The proposed multi-channel system is validated by measuring the ballistocardiogram (BCG) and pulse wave, which paves the way for future portable remote human physiological signals monitoring devices. Full article

This paper presents a novel computational algorithm to estimate blood volume decompensation state based on machine learning (ML) analysis of multi-modal wearable-compatible physiological signals. To the best of our knowledge, our algorithm may be the first of its kind which can not only discriminate normovolemia from hypovolemia but also classify hypovolemia into absolute hypovolemia and relative hypovolemia. We realized our blood volume classification algorithm by (i) extracting a multitude of features from multi-modal physiological signals including the electrocardiogram (ECG), the seismocardiogram (SCG), the ballistocardiogram (BCG), and the photoplethysmogram (PPG), (ii) constructing two ML classifiers using the features, one to classify normovolemia vs. hypovolemia and the other to classify hypovolemia into absolute hypovolemia and relative hypovolemia, and (iii) sequentially integrating the two to enable multi-class classification (normovolemia, absolute hypovolemia, and relative hypovolemia). We developed the blood volume decompensation state classification algorithm using the experimental data collected from six animals undergoing normovolemia, relative hypovolemia, and absolute hypovolemia challenges. Leave-one-subject-out analysis showed that our classification algorithm achieved an F1 score and accuracy of (i) 0.93 and 0.89 in classifying normovolemia vs. hypovolemia, (ii) 0.88 and 0.89 in classifying hypovolemia into absolute hypovolemia and relative hypovolemia, and (iii) 0.77 and 0.81 in classifying the overall blood volume decompensation state. The analysis of the features embedded in the ML classifiers indicated that many features are physiologically plausible, and that multi-modal SCG-BCG fusion may play an important role in achieving good blood volume classification efficacy. Our work may complement existing computational algorithms to estimate blood volume compensatory reserve as a potential decision-support tool to provide guidance on context-sensitive hypovolemia therapeutic strategy. Full article