Search Results (2,724)

Pregnant and postpartum people (PPPs) face heightened risk for HIV acquisition, yet depression and trauma-related symptoms can undermine adherence to pre-exposure prophylaxis (PrEP). To inform the development of a brief mental health-focused adherence intervention, we explored the impacts of depression and posttraumatic stress disorder (PTSD) symptoms on PrEP use among PPPs in Cape Town, South Africa. Twenty-eight PPPs with elevated symptoms of depression and/or PTSD and recent PrEP adherence challenges completed qualitative interviews. Six antenatal providers were also interviewed. Thematic analysis revealed three key findings with subthemes that deepen exploration of each theme: (1) depression and PTSD symptoms contributed to missed PrEP doses or late pickups by increasing doubt about PrEP efficacy, amplifying pill burden, intensifying avoidance and withdrawal (e.g., hypersomnia and disengagement from providers), and disrupting memory through rumination and emotional overload; (2) most PPPs preferred support from professional counselors, while a minority preferred informal support; and (3) intervention design considerations included aligning patient and provider goals, selecting between individual or group formats, and addressing integration barriers such as staffing and space constraints. Providers affirmed the need for embedded mental health support. Intervention strategies that increase PrEP knowledge and motivation while targeting emotional withdrawal, fatigue, and cognitive overload may improve adherence and reduce HIV risk in this population. Full article

Through three-wave longitudinal research, a survey was conducted with 3200 college students from a university in China, Hebei Province, with an interval of approximately one year between each survey. In the third wave of surveys, 1495 valid samples were obtained. The questionnaires included the Resilience Scale (RS-11), the Social Support Questionnaire (F-SozU K-14), and the Depression Anxiety Stress Scale (DASS-21). There are significant differences in social support and negative emotions across gender variables. There are significant differences in resilience, social support, and negative emotions across travel frequency in the past year. There are significant differences in negative emotions across vegetarianism. Resilience and social support measured in three waves were significantly negatively correlated with negative emotions, while resilience and social support were significantly positively correlated. The results of the random intercept cross-lagged panel model analysis indicate that W1 social support can significantly negatively predict W2 negative emotions, and W2 negative emotions can significantly negatively predict W3 resilience and social support. Ineffective or insufficient social support can cause negative emotions to negatively impact the resilience process while further reducing the individual’s perception of social support. Full article

Background/Objectives: Chronic stress contributes to obesity through maladaptive eating behaviors, including emotional eating (eating due to negative emotions) and binge eating (consuming large amounts of food with a loss of control). A theoretical model suggests that emotional eating can escalate to binge eating along a severity continuum, but this sequential pathway from stress to higher body mass index (BMI) has remained empirically untested. Therefore, this study examined a serial mediation model in which perceived stress predicts BMI sequentially through emotional eating and then binge eating. Methods: In this cross-sectional study, 272 Korean adults completed the Perceived Stress Scale, the Dutch Eating Behavior Questionnaire (emotional eating subscale), and the Binge Eating Scale. The serial mediation model was tested using PROCESS macro model 6, with age, gender, and education as covariates. Results: The serial mediation pathway (stress → emotional eating → binge eating → BMI) was statistically significant (indirect effect B = 0.071, 95% CI [0.041, 0.112]). A separate simple mediation path through binge eating alone was also significant (B = 0.056, 95% CI [0.018, 0.102]), whereas the path through emotional eating alone was not significant. The total indirect effect (B = 0.108, 95% CI [0.052, 0.172]) was significant, indicating that the influence of stress on BMI was fully mediated by the eating behaviors modeled. Conclusions: This study provides the first empirical evidence supporting a sequential pathway from stress to elevated BMI via the progression from emotional to binge eating. The findings support the overeating continuum model and highlight binge eating as a pivotal mediator. This behavioral progression suggests that emotional and binge eating are distinct stages, offering crucial opportunities for tailored prevention and intervention. Full article

Alcohol consumption during pregnancy and lactation remains a significant global issue. Preventive policies have proven insufficient, and consumption rates remain high, mainly due to a lack of awareness, the misconception that only high alcohol intake harms the fetus, inconsistent medical advice, and pre-existing alcohol use disorders. Alcohol consumption is linked to child harm during critical stages of development. Using a recently published model of fetal alcohol spectrum disorder (FASD) developed by our group, we analyzed brain changes in mothers who consumed alcohol during pregnancy and lactation and the behavioral consequences at the emotional-cognitive level and in caring for their offspring. We also considered the previous drinking history, using the paradigm of voluntary pre-gestational alcohol consumption. In addition, from gestational day 7 (GD7) until the day of sacrifice, mothers received a 3 g/kg dose of alcohol every 12 h via gavage. Our findings revealed deficiencies in maternal care, anxiety and depressive-like behavior, and aversive stimulus learning disturbances. These were associated with changes in gene targets linked to stress-axis regulation, reward circuits, and neuroplasticity. Additionally, we observed increased microgliosis and astrogliosis, indicating neuroinflammation in brain regions involved in cognition and emotional states’ regulation. Full article

The COVID-19 pandemic unprecedentedly challenged families worldwide, yet little is known about how parents from diverse cultural contexts retrospectively interpret their parenting roles and coping strategies. This study explores parenting adjustments two years after the pandemic’s onset among five cultural groups: Bulgarian and Spanish (Eastern and Western Europe), Israeli Arabs and Jews (Middle East), and U.S. families. Fifty parents, primarily mothers of children aged 2–8, were recruited through snowball sampling. Semi-structured interviews were conducted using the Parenting Pentagon Model (PPM), which includes five constructs: Partnership, Parental Leadership, Love, Encouraging Independence, and Adherence to Rules. Data were analyzed using grounded theory and directed content analysis. Across cultures, Love and Parental Leadership were central to maintaining emotional stability and family cohesion. Partnership showed cultural variation: Bulgarian and Spanish parents often shared responsibilities, while U.S. mothers reported handling childcare alone, heightening work–life tension. Israeli-Arab fathers became more involved in caregiving, while Israeli-Jewish mothers described both strengthened and strained partnerships. Coping strategies were shaped by cultural values and family demographics (e.g., family size). The findings emphasize parents’ vital role in fostering family resilience during crises and stress the importance of culturally sensitive support to enhance families’ adaptive capacity for future challenges. Full article

Background. Living with a stoma entails profound changes in a person’s life, affecting physical, psychological, and social well-being. Patients often face challenges related to body image, interpersonal relationships, and self-esteem. A stoma can impair quality of life, trigger feelings of shame and limit freedom of movement. Objectives. To assess the subjective perception of quality of life and related psychophysical consequences in individuals with an intestinal stoma. To evaluate the level of perceived support from healthcare professionals involved in the care pathway. Methods. This is a descriptive observational study conducted through the administration of an online questionnaire. The sample includes 189 adult patients with an intestinal stoma. Results. Data analysis revealed that participants aged ≥65 years and those with a permanent stoma reported higher quality of life scores compared to younger individuals or those with a temporary stoma. An inverse correlation emerged between quality of life and perceived stress (p < 0.001); in particular, pain and social embarrassment were strongly associated with higher levels of stress. The enterostomal therapy nurse was identified as a key figure in the care pathway (70.4%). Conclusions. The findings highlight the need for person-centered care that addresses not only clinical aspects but also emotional and relational dimensions. Enhancing the role of trained professionals, such as enterostomal therapy nurses, and promoting targeted educational interventions may contribute to improving the quality of life in patients living with a stoma. Full article

Recent years have witnessed a concerning rise in early-onset eating disorders (EDs), prompting a re-evaluation of their etiology, diagnosis, and treatment within pediatric populations. This perspective article synthesizes emerging evidence on the multifactorial origins of EDs in children, emphasizing a biopsychosocial framework that integrates genetic, epigenetic, psychological, and environmental factors. While early manifestations often diverge from adolescent or adult profiles—marked by somatic complaints, selective eating, and ritualistic behaviors—the disorders significantly interfere with developmental milestones. The COVID-19 pandemic has further exacerbated vulnerabilities, acting as a catalyst for disordered eating behaviors through increased familial stress, isolation, and disrupted routines. Central to this framework is the role of parental psychopathology and parent–child feeding interactions, which profoundly shape children’s emotional regulation and attachment patterns. Recent studies also underscore genetic susceptibilities—especially variants in the DRD4 and DAT1 genes—and epigenetic modifications that may mediate the transmission of risk across generations. The article reviews evidence from observational and genomic studies, highlighting how altered gene expression linked to early environmental stress contributes to the heterogeneity of EDs. Finally, it evaluates prevention and intervention strategies, including family-based treatments, digital health tools, and school-based programs. These strategies are essential for timely detection, individualized care, and reducing long-term impairment. Overall, the paper advocates for a nuanced understanding of EDs in children—recognizing their complex origins and developmental implications—to inform clinical practice, public health policy, and future research in pediatric mental health. Full article

Background: Excessive parental control has been found to be associated with an increasing risk of emotional eating in children, yet the potential moderating role of emotion regulation abilities remains unclear. This study investigated the relationships between different types of parental control and emotional eating, as well as the mediating effects of specific emotion regulation strategies and negative emotions. Methods: A cross-sectional online survey was conducted with 1167 Chinese college students (62.5% females, age: 20.23 ± 1.50 years) recruited via social media. Participants completed the Parental Control Scale, Emotion Regulation Questionnaire, Depression Anxiety Stress Scales, and Dutch Eating Behavior Questionnaire. Data were analyzed using SPSS and PROCESS (Model 81), with BMI, age, and gender controlled as a covariate. Mediation effects were tested using the 95% bias-corrected bootstrap confidence intervals (based on 5000 samples). Results: The results indicate that (1) both parental behavioral control and psychological control were significantly positively correlated with emotional eating, with effect sizes ranging from small to moderate; (2) anxiety and stress in negative emotions partially mediate the relationship between the two dimensions of parental control and emotional eating, while depression did not serve as a mediator in this relationship; (3) expression suppression and stress chain-mediated between the two dimensions of parental control and emotional eating; expression suppression and anxiety chain-mediated between parental psychological control and emotional eating. Conclusions: Higher parental control is associated with increased emotional eating behaviors in children. Anxiety, stressful emotions, and expressive suppression play significant roles. These findings suggest new interventions to reduce emotional eating and associated overweight risks in college students. Full article

Biometric authentication using human physiological and behavioral characteristics has been widely adopted, with speaker verification attracting attention due to its convenience and noncontact nature. Conventional speaker verification systems remain vulnerable to spoofing attacks, however, often requiring integration with separate spoofed speech detection models. In this work, the authors propose an emotion-dependent speaker verification system that integrates speaker characteristics with emotional speech characteristics, enhancing robustness against spoofed speech without relying on additional classification models. By comparing acoustic characteristics of emotions between registered and verification speech using pretrained models, the proposed method reduces the equal error rate compared to conventional speaker verification systems, achieving an average equal error rate of 1.13% for speaker verification and 17.7% for the anti-spoofing task. Researchers additionally conducted a user evaluation experiment to assess the usability of emotion-dependent speaker verification. The results indicate that although emotion-dependent authentication was initially cognitively stressful, participants adapted over time, and the burden was significantly reduced after three sessions. Among the tested emotions (anger, joy, sadness, and neutral), sadness proved most effective, with stable scores, a low error rate, and minimal user strain. These findings suggest that neutral speech is not always the optimal choice for speaker verification and that well-designed emotion-dependent authentication can offer a practical and robust security solution. Full article

Background/Objectives: Although COVID-19 may cause cognitive impairments for up to six months, the long-term effects of mild cases remain unclear. Given their high exposure and critical role in public health, assessing this impact on healthcare workers is essential. Aim: The present study aimed to examine the cognitive and emotional effects of mild COVID-19 in 92 healthcare workers one year after infection. Methods: In total, 50 had experienced mild COVID-19, while 42 had not been infected. Participants completed a neuropsychological assessment evaluating attention, memory, and executive functions, along with self-reported measures of anxiety, depression, post-traumatic stress, occupational stress, and burnout. Results: No significant cognitive differences were observed between the groups. However, both exhibited moderate-to-severe psychological distress, with the COVID-19 group showing higher trait anxiety (p = 0.032). Emotional symptoms were significantly associated with neuropsychological performance—higher burnout (ρ from −0.20 to −0.28, p < 0.05) and stress (ρ from −0.25 to −0.33, p < 0.01) correlated with slower responses and more errors in tasks such as the D2 variation index, TESEN execution speed, Rey–Osterrieth Figure recall, and Digit Span forward span. Conclusions: These findings suggest no long-term cognitive impairment after mild COVID-19 but highlight the substantial emotional toll of the pandemic on healthcare workers. Future research should explore cognitive reserve as a protective factor. Full article

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder primarily characterized by memory loss and cognitive decline, which significantly impacts patients’ quality of life and imposes substantial emotional, practical, and economic burdens on their families. As the most common cause of senile dementia, AD currently affects approximately 50 million people worldwide, with projections indicating a threefold increase by 2050 due to rising life expectancy and an aging global population. Diagnosis of AD remains challenging. Neuroimaging techniques reveal atrophy in critical brain regions, particularly in the cortex, hippocampus, and limbic system, which are essential substrates for memory, personality changes, and other cognitive functions. The hallmark molecular changes associated with AD include the accumulation of β-amyloid plaques and the formation of tau protein tangles. Several underlying mechanisms contribute to neuron loss, such as oxidative stress, neuroinflammation, microbial dysbiosis, and insulin resistance. In this context, exosomes—small extracellular vesicles that facilitate cell communication—transport proteins, DNA, mRNA, and non-coding RNA (ncRNA), all of which play a significant role in the neurobiology of AD. Furthermore, emerging research indicates that exosomal ncRNAs may serve as promising biomarkers for AD, offering the possibility of improved diagnostic precision. This review explores the potential of exosomal ncRNAs—specifically circular RNAs and microRNAS—as non-invasive biomarkers for AD, highlighting recent advances and future directions in translational studies. Full article

Background: Threatened preterm labor is associated with heightened emotional distress in pregnant women, including anxiety, guilt, and depressive symptoms. Effective coping relies on psychosocial resilience, particularly emotional suppression and perceived social support. This study examined the mediating role of social support in the relationship between anxiety and emotional suppression. Methods: The study was conducted in Poland between December 2024 and June 2025 among 213 women hospitalized due to threatened preterm labor. Participants completed the Berlin Social Support Scales, the State–Trait Anxiety Inventory, the Courtauld Emotional Control Scale, and a structured interview. Results: Women hospitalized for threatened preterm labor have moderate levels of anxiety as a state (M = 44.08 ± 10.59) and trait (M = 39.75 ± 9.99). Mediation analyses revealed that two dimensions of social support—perceived available support and Buffering–Protective support—significantly influenced the relationship between anxiety and emotional suppression (anger, depression and anxiety). In contrast, need for support, support seeking, and Currently Received Support were not significant mediators. Conclusions: The results indicate a complex interplay between anxiety, perceived support, and emotional suppression. The hypothesized simple buffering model was not confirmed. However, perceived available support was associated with reduced emotional suppression, suggesting a protective role. Buffering–Protective Support showed an activating effect, possibly encouraging emotional inhibition in stressful situations. These results underscore the importance of assessing perceived social support in clinical settings and tailoring psychological interventions for pregnant women at risk of preterm labor. Full article

Background: Undergraduate nursing students (UNSs) often enter clinical training just as they are still mastering the emotional labor of the profession. In Nepal, where teaching hierarchies discourage upward dialogue and hospitals routinely struggle with overcrowding, supply shortages, and outward nurse migration, these learners confront a distinct, under-documented burden of psychological distress. Objective: This study examines how UNSs interpret, negotiate, and cope with the mental health challenges that arise at the intersection of cultural deference, resource scarcity, and migration-fueled uncertainty. Methods: A qualitative design employing reflexive thematic analysis (RTA), guided by the Reflexive Thematic Analysis Reporting Guidelines (RTARG), was used. Fifteen second-, third-, and fourth-year Bachelor of Science in Nursing students at a major urban tertiary institution in Nepal were purposively recruited via on-campus digital flyers and brief in-class announcements that directed students (by QR code) to a secure sign-up form. Participants then completed semi-structured interviews; audio files were transcribed verbatim and iteratively analyzed through an inductive, reflexive coding process to ensure methodological rigor. Results: Four themes portray a continuum from silenced struggle to systemic constraint. First, Shrouded Voices, Quiet Connections captures how students confide only in trusted peers, fearing that formal disclosure could be perceived as weakness or incompetence. Second, Performing Resilience: Masking Authentic Struggles describes the institutional narratives of “strong nurses” that drive students to suppress anxiety, adopting scripted positivity to satisfy assessment expectations. Third, Power, Hierarchy, and the Weight of Tradition reveals that strict authority gradients inhibit questions in classrooms and clinical placements, leaving stress unvoiced and unaddressed. Finally, Overshadowed by Systemic Realities shows how chronic understaffing, equipment shortages, and patient poverty compel students to prioritize patients’ hardships, normalizing self-neglect. Conclusions: Psychological distress among Nepalese UNSs is not an individual failing but a product of structural silence and resource poverty. Educators and policymakers must move beyond resilience-only rhetoric toward concrete reforms that dismantle punitive hierarchies, create confidential support avenues, and embed collaborative pedagogy. Institutional accountability—through regulated workloads, faculty-endorsed wellbeing forums, and systematic mentoring—can shift mental health care from a private struggle to a shared professional responsibility. Multi-site studies across low- and middle-income countries are now essential for testing such system-level interventions and building a globally resilient, compassionate nursing workforce. Full article

This study investigated consumer perception of food insecurity by refining data collected from social media platforms. Text mining and TF-IDF were used to extract core keywords closely related to food insecurity and analyze their meanings. In addition, time series analysis and sentiment analysis were used to examine temporal and emotional changes. The analysis results showed that keywords, such as health, stress, mental, and depression, appeared frequently, indicating that food insecurity is closely related to psychological and mental problems. In addition, consumers showed high emotional sensitivity to essential nutrients, such as vitamin D, magnesium, calcium, and omega. Furthermore, stress indices and mental and physical response indices increased simultaneously during this period, indicating that food insecurity is a factor that causes emotional and physical responses. The results of the sentiment analysis showed that negative emotions (anxiety, fear, and sadness) were higher than positive emotions, suggesting that discussions related to food insecurity have a negative emotional impact. Full article

Background: Assistance dogs can support children with autism by improving emotional regulation and social functioning, but access is limited. The Family Dog Service was developed to help families of autistic children gain similar benefits through companion dogs. It offers tailored support for selecting, training, and integrating a dog into the home. This study explored parent perspectives on the service and perceived impacts of companion dogs. Methods: A cross-sectional online survey was conducted among UK residents who attended Family Dog Service workshops. The survey included demographic data, mental health and wellbeing measures, and questions about human–animal interactions. Quantitative data were analysed descriptively; qualitative responses underwent thematic analysis. Results: Of 118 participants, 101 (85.6%) owned a dog, while 17 (14.4%) were considering acquisition. Most owners reported improvements in their child’s mood (75.2%; n = 76) and reduced anxiety-related behaviours (70.3%, n = 71) following dog acquisition. Nearly half (49.5%, n = 50) rated the child–dog relationship as ‘very’ or ‘extremely’ positive within the first month, increasing to 86.1% (n = 87) by the time of data collection. Families also reported enhanced dynamics and reduced caregiver stress. Despite some challenges, the service was valued for its autism-specific guidance and ongoing support. Conclusions: The Family Dog Service may offer a practical, accessible alternative to assistance dogs, supporting autistic children’s wellbeing and strengthening family relationships through positive interactions between children and their dogs. Full article