Sign in to use this feature.

Years

Between: -

Subjects

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Journals

Article Types

Countries / Regions

Search Results (72)

Search Parameters:
Keywords = first record in Korea

Order results
Result details
Results per page
Select all
Export citation of selected articles as:
19 pages, 1563 KB  
Review
Autonomous Earthwork Machinery for Urban Construction: A Review of Integrated Control, Fleet Coordination, and Safety Assurance
by Zeru Liu and Jung In Kim
Buildings 2025, 15(14), 2570; https://doi.org/10.3390/buildings15142570 - 21 Jul 2025
Viewed by 672
Abstract
Autonomous earthwork machinery is gaining traction as a means to boost productivity and safety on space-constrained urban sites, yet the fast-growing literature has not been fully integrated. To clarify current knowledge, we systematically searched Scopus and screened 597 records, retaining 157 peer-reviewed papers [...] Read more.
Autonomous earthwork machinery is gaining traction as a means to boost productivity and safety on space-constrained urban sites, yet the fast-growing literature has not been fully integrated. To clarify current knowledge, we systematically searched Scopus and screened 597 records, retaining 157 peer-reviewed papers (2015–March 2025) that address autonomy, integrated control, or risk mitigation for excavators, bulldozers, and loaders. Descriptive statistics, VOSviewer mapping, and qualitative synthesis show the output rising rapidly and peaking at 30 papers in 2024, led by China, Korea, and the USA. Four tightly linked themes dominate: perception-driven machine autonomy, IoT-enabled integrated control systems, multi-sensor safety strategies, and the first demonstrations of fleet-level collaboration (e.g., coordinated excavator clusters and unmanned aerial vehicle and unmanned ground vehicle (UAV–UGV) site preparation). Advances include centimeter-scale path tracking, real-time vision-light detection and ranging (LiDAR) fusion and geofenced safety envelopes, but formal validation protocols and robust inter-machine communication remain open challenges. The review distils five research priorities, including adaptive perception and artificial intelligence (AI), digital-twin integration with building information modeling (BIM), cooperative multi-robot planning, rigorous safety assurance, and human–automation partnership that must be addressed to transform isolated prototypes into connected, self-optimizing fleets capable of delivering safer, faster, and more sustainable urban construction. Full article
(This article belongs to the Special Issue Automation and Robotics in Building Design and Construction)
Show Figures

Figure 1

16 pages, 1065 KB  
Article
First Serologic Analysis of Antibodies Against African Swine Fever Virus Detected in Domestic Pig Farms in South Korea from 2019 to 2024
by Seong-Keun Hong, Mugyeom Moon, Ki-Hyun Cho, Hae-Eun Kang, Jong-Soo Lee and Yeon-Hee Kim
Pathogens 2025, 14(6), 581; https://doi.org/10.3390/pathogens14060581 - 11 Jun 2025
Viewed by 1383
Abstract
Background: African swine fever (ASF) is a crucial socioeconomic setback to South Korea’s swine industry. This study aimed to determine seropositivity for ASF virus (ASFV) in pigs that appeared to be infected on farms with reported ASF outbreaks. Methods: A total of 2232 [...] Read more.
Background: African swine fever (ASF) is a crucial socioeconomic setback to South Korea’s swine industry. This study aimed to determine seropositivity for ASF virus (ASFV) in pigs that appeared to be infected on farms with reported ASF outbreaks. Methods: A total of 2232 sera from ASF outbreaks (2019–2024) in South Korea were collected. Two enzyme-linked immunosorbent assay (ELISA) kits were used to detect ASFV antibodies, and an immunoperoxidase test (IPT) was used as a confirmatory test following the method recommended by the World Organisation for Animal Health in the Manual of Diagnostic Tests and Vaccines for Terrestrial Animals. Also, spatial clustering was identified using the Density-Based Spatial Clustering of Applications with Noise (DBSCAN) model to understand ASF hotspots in the wild boar population and assess the spatial relationship between the hotspots and ASF antibody-positive domestic pig farms. Results: Antibodies were first detected in Hwacheon in 2020, but by 2024, only 1.43% of pigs had detectable antibodies against ASFV. Although this percentage is still low, the number of antibody-positive pigs is gradually increasing. Additionally, 32 positive samples were found from nine pig farms with outbreaks, and these samples were confirmed positive in both the two ELISA tests and the IPT. The highest seropositivity was recorded at the finishing stage of pig production. When compared to the confirmatory IPT, both blocking and competition ELISA demonstrated high diagnostic sensitivities. The statistical association between ASF antibody-positive farms and wild boars were analyzed using Fisher’s exact test, yielding a significant p-value of 0.007. This indicates a strong correlation, as eight out of nine ASF-seropositive farms were located within hotspots that were significantly associated. Conclusions: Our findings provide valuable insights into ASFV antibody detection in South Korea and demonstrate a statistical association between farms housing pigs with ASFV antibodies and hotspots of ASFV-infected wild boars. Confirmatory tests, such as the IPT, are needed. These insights will contribute to the improvement of surveillance and biosecurity measures for swine farms. Full article
(This article belongs to the Special Issue Diagnostics of Emerging and Re-Emerging Pathogens)
Show Figures

Figure 1

14 pages, 2782 KB  
Article
Yearly Spatiotemporal Patterns of COVID-19 During the Pandemic Period: An In-Depth Analysis of Regional Trends and Risk Factors in the Republic of Korea
by Chiara Achangwa, Jung-Hee Park and Moo-Sik Lee
COVID 2025, 5(3), 40; https://doi.org/10.3390/covid5030040 - 11 Mar 2025
Viewed by 1384
Abstract
Background: South Korea was one of the first countries to experience the Coronavirus disease (COVID-19) epidemic, and the regional-level trends and patterns in the incidence and case-fatality rates have been observed to evolve with time. This study established yearly spatiotemporal evolution patterns of [...] Read more.
Background: South Korea was one of the first countries to experience the Coronavirus disease (COVID-19) epidemic, and the regional-level trends and patterns in the incidence and case-fatality rates have been observed to evolve with time. This study established yearly spatiotemporal evolution patterns of COVID-19 by region and identified possible regional risk factors accounting for the observed spatial variations. Methods: COVID-19 data between 20 January 2020 and 31 August 2023 were collected from the Korean Centers for Disease Prevention and Control (KCDA). We generated epidemic curves and calculated the yearly incidence and case-fatality rates for each region. In addition, choropleth maps for the location quotient of cases and deaths to visualize yearly regional intensities were generated and the Moran’s I calculated. Associations between the incidence and case-fatality rates with regional risk factors were estimated using regression models. All analyses were performed in R version 4.4.2. Results: We noted a significant difference in the incidence rate by year, with 2022 recording the highest for all regions. A consistent and significant spatial autocorrelation for cases and deaths across all years was observed with Moran I values above 0.4 (p < 0.05). There was a positive association of COVID-19 incidence rates with the population density (RR = 0.02, CI: 0.01–0.04, p = 0.03), percentage aged 60 years and above (RR = 0.03, CI: 0.01–0.05, p = 0.01), smoking prevalence (women) (RR = 0.79, CI: 0.54–1.04, p = 0.01), and diabetes prevalence (women) (RR = 0.51, CI: 0.32–0.71, p = 0.04). Conclusions: The spatiotemporal evolution patterns of COVID-19 in Korea consisted of oscillating hot and cold spots across the pandemic period in each region. These findings provide a useful reference to the government as it continues with the routine surveillance of COVID-19 across the country. Full article
(This article belongs to the Section COVID Public Health and Epidemiology)
Show Figures

Figure 1

14 pages, 21258 KB  
Article
Evaluating the Sounds Produced by Pacific Cod (Gadus macrocephalus, Gadidae) During the Spawning Season
by Sungho Cho, Donhyug Kang, Hansoo Kim, Mira Kim and Sunhyo Kim
J. Mar. Sci. Eng. 2025, 13(2), 378; https://doi.org/10.3390/jmse13020378 - 18 Feb 2025
Viewed by 751
Abstract
Marine organisms produce sounds for various purposes, including spawning, avoidance, and migration, with each species exhibiting unique acoustic characteristics. This study observed the grunt sounds of Pacific cod (Gadus macrocephalus) during the spawning season for the first time using passive acoustic [...] Read more.
Marine organisms produce sounds for various purposes, including spawning, avoidance, and migration, with each species exhibiting unique acoustic characteristics. This study observed the grunt sounds of Pacific cod (Gadus macrocephalus) during the spawning season for the first time using passive acoustic monitoring (PAM) techniques. Acoustic signals were recorded continuously for about one month at an aquaculture fish farm in Korea. From these recordings, 1208 grunt sounds of Pacific cod were extracted using an automatic grunt detector, and statistical time–frequency parameters were estimated. On average, the grunt sounds consisted of 29 pulses at 6.5 ms intervals within a duration of 205 ms, with a pulse rate of 122.6 per second. The periodic pulse-type signal creates multiple harmonic frequencies on the spectrogram, characterized by time-harmonic modulation with a slope of −240 Hz/s. The mth harmonic frequency distribution ranged from 162 to 822 Hz, with a median source level of 122.6 dB re 1 μPa at 1 m. These findings provide essential scientific data for understanding Pacific cod communication during the spawning season and can aid in identifying spawning sites, conserving habitats, and managing biological resources, contributing to marine ecosystem protection and sustainable management. Full article
(This article belongs to the Special Issue Advanced Research in Marine Environmental and Fisheries Acoustics)
Show Figures

Figure 1

17 pages, 2080 KB  
Article
Assessment of Antimicrobial Use for Companion Animals in South Korea: Developing Defined Daily Doses and Investigating Veterinarians’ Perception of AMR
by Sun-Min Kim, Heyong-Seok Kim, Jong-Won Kim and Kyung-Duk Min
Animals 2025, 15(2), 260; https://doi.org/10.3390/ani15020260 - 17 Jan 2025
Viewed by 1898
Abstract
There are global concerns regarding the transmission of antimicrobial-resistant pathogens from animals to humans. Especially, companion animals are increasingly recognized as a potential source due to their close interactions with people, despite a limited number of reported cases. Although, social demands regarding comprehensive [...] Read more.
There are global concerns regarding the transmission of antimicrobial-resistant pathogens from animals to humans. Especially, companion animals are increasingly recognized as a potential source due to their close interactions with people, despite a limited number of reported cases. Although, social demands regarding comprehensive surveillance for antimicrobial resistance (AMR) among companion animals are highlighted, there is a lack of a relevant system in South Korea. In this regard, we conducted preliminary investigation on antimicrobial use (AMU) among small animal clinics, along with veterinary practitioner’s knowledge and attitude regarding this issue in South Korea. We collected data on 684,153 antimicrobial prescription visits for canine and feline patients from 2019 to 2022 at 100 veterinary facilities in South Korea, using electronic medical records. To evaluate antimicrobial use (AMU) and facilitate comparisons across institutions and time periods, we developed the Defined Daily Dose for Animals (DDDA) and the Defined Animal Daily Dosages per 1000 Animal-Days (DAPD). In addition, we conducted an online survey of 362 veterinary practitioners, which included questions on their perceptions, attitudes, and practices regarding antimicrobial prescriptions. Simple frequency analyses were performed to examine temporal trends, regional differences and variations by facility size in AMU, and to summarize survey responses. Descriptive analysis using data from 100 veterinary clinics revealed a rising trend in AMU between 2019 and 2022, with higher usage observed in larger clinics and non-capital regions. DDDA values for dogs were generally higher than for cats. Survey results highlighted that, while veterinarians exhibited high awareness of AMR, prescribing practices were significantly influenced by clinical judgments and owner demands, often deviating from established guidelines. The adoption of an electronic veterinary prescription management system (e-Vet) was proposed to enhance antimicrobial stewardship. However, concerns regarding the system’s efficiency and administrative burden were prominent. To our best knowledge, this study provided DDDA for companion animals for the first time in South Korea. Although the indicator should be improved with more comprehensive data and expert opinion, our study showed that it enables reasonable situation analysis regarding AMU in companion animals. The identified factors that affect veterinarians’ prescription practices can also be used to design an effective strategy for promoting appropriate antimicrobial usage. Full article
(This article belongs to the Section Companion Animals)
Show Figures

Figure 1

10 pages, 674 KB  
Article
Colonic Polyp Study: Differences in Adenoma Characteristics Based on Colonoscopy History over 5-Year Follow-Up Period
by Sang Hyun Park, Kwang Il Hong, Hyun Chul Park, Young Sun Kim, Gene Hyun Bok, Kyung Ho Kim, Dong Suk Shin, Jae Yong Han, Young Kwan Kim, Yeun Jong Choi, Soo Hoon Eun, Byung Hoon Lim, Kyeong Kun Kwack and The Korean Society of Digestive Endoscopy Polyp Study
J. Clin. Med. 2025, 14(1), 194; https://doi.org/10.3390/jcm14010194 - 31 Dec 2024
Cited by 1 | Viewed by 2042
Abstract
Background: Timely detection and removal of colonic adenomas are critical for preventing colorectal cancer. Methods: This study analyzed differences in colonic adenoma characteristics based on colonoscopy history by reviewing the medical records of 14,029 patients who underwent colonoscopy between January and [...] Read more.
Background: Timely detection and removal of colonic adenomas are critical for preventing colorectal cancer. Methods: This study analyzed differences in colonic adenoma characteristics based on colonoscopy history by reviewing the medical records of 14,029 patients who underwent colonoscopy between January and June 2020 across 40 primary medical institutions in Korea. Results: Adenoma and advanced neoplasia characteristics varied significantly with colonoscopy history (p < 0.05). In the first-time colonoscopy group, adenomas were more frequent in the sigmoid colon (S-colon) and rectum, with Is features and non-granular laterally spreading tumors. Advanced neoplasia was also more common in the S-colon and rectum, with Is and advanced-type features. In the <5-year group, adenomas were predominantly found in the transverse colon (T-colon) and descending colon (D-colon), with IIa and IIb features. Advanced neoplasia in this group was more frequent in the cecum and T-colon, with IIa and IIb features and laterally spreading tumors. In the ≥5-year group, adenomas were more commonly located in the ascending colon (A-colon) and cecum, with Ip features, while advanced neoplasia was more frequent in the A-colon and D-colon, also with Ip features. Conclusions: Although every segment of the colorectum should be carefully observed regardless of colonoscopy history, these findings suggest that prioritizing specific colonic segments for examination based on colonoscopy history may improve adenoma detection rates and reduce the incidence of colorectal cancer. However, further large-scale, prospective studies are needed to confirm these findings and support their application in clinical practice. Full article
(This article belongs to the Special Issue Updates in Digestive Diseases and Endoscopy)
Show Figures

Figure 1

16 pages, 5381 KB  
Article
First Record of a Rare New Species of Dracognomus (Nematoda: Draconematidae) from the Northwest Pacific Ocean
by Seungyeop Han and Hyun Soo Rho
Diversity 2024, 16(12), 776; https://doi.org/10.3390/d16120776 - 20 Dec 2024
Viewed by 917
Abstract
We report the discovery of a novel free-living marine nematode, Dracognomus elongatus sp. nov., from the genus Dracognomus Allen & Noffsinger, 1978 (Nematoda: Draconematidae), collected from geniculate coralline algal assemblages in the intertidal zone along the eastern coast of Korea in the Northwest [...] Read more.
We report the discovery of a novel free-living marine nematode, Dracognomus elongatus sp. nov., from the genus Dracognomus Allen & Noffsinger, 1978 (Nematoda: Draconematidae), collected from geniculate coralline algal assemblages in the intertidal zone along the eastern coast of Korea in the Northwest Pacific Ocean. Dracognomus elongatus sp. nov. is distinguished from its congeners by several key features: a relatively long body length (522 µm), densely developed minute spine-like ornamentation along the margins of body annules, small pore-shaped amphids (2 µm) with membranous tubes filled with corpus gelatum extending to the fifth body annule, twelve modified cephalic adhesion tubes located posterior to the rostrum, eight pairs of modified adhesion tubes in the mid-body region, an arrangement of both normal and modified subventral adhesion tubes (three pairs of each), disc-shaped tips on sublateral adhesion tubes, absence of copulatory thorns in males, and the presence of three pairs of short setae with no protuberances on the non-annulated tail end. Morphological details and illustrations were obtained using differential interference contrast microscopy. We also provide information on the geographic distribution and comparative characteristics of species within the genus Dracognomus, along with a schematic ventral view of a congener illustrating the arrangement of posterior adhesion tubes and copulatory thorns. Additionally, we present a species-level pictorial dichotomous key. Dracognomus elongatus sp. nov. is the eighth described species of this rare genus and marks the first record of Dracognomus in the Northwest Pacific Ocean. Full article
(This article belongs to the Special Issue Dynamics of Marine Communities)
Show Figures

Figure 1

16 pages, 1863 KB  
Article
Growth and Yield Response of Soybean (Glycine max L.) in Relation to Sowing Date in the Southern Region of South Korea
by Jinhee Seo, Jaesung Park, Mansoo Choi, Kiyeol Jung, Hyenchung Chun, Sanghun Lee, Donghyeok Gong, Se Eun Chae, Seung Ho Jeon and Dong-Kyung Yoon
Agronomy 2024, 14(11), 2624; https://doi.org/10.3390/agronomy14112624 - 7 Nov 2024
Cited by 1 | Viewed by 1746
Abstract
A double-cropping system is widely adopted in southern Korea, in which the sowing date of the second crop (soybean) can be delayed depending on the growth period of the first crop and weather conditions. Soybean yields may be reduced because of the shorter [...] Read more.
A double-cropping system is widely adopted in southern Korea, in which the sowing date of the second crop (soybean) can be delayed depending on the growth period of the first crop and weather conditions. Soybean yields may be reduced because of the shorter vegetative growth period and earlier flowering. This study examined soybean growth and yield responses as plant populations at a late planting date. A field experiment was conducted in the upland field at the Department of Southern Area Crop Science in Miryang, Gyeongsangnam-do, for two years (2022–2023) using four cultivars (Seonyu 2, Jungmo 3015, Seonpung, and Jangpung). A split-plot block design was used with three replications. The main plots had four sowing dates at 10-day intervals from 25 June to 25 July. The date of maturity was recorded, and the yield components and yield were examined after harvesting. The optimum planting population for maximizing the soybean yield with late planting was compared with the standard population result. To maintain pre- and post-crop yields and cultivate stable production, the sowing date limit for early maturing soybeans was July 15 and that for mid-maturing soybeans was July 5. The results highlight the potential to produce an economic soybean production level. Full article
(This article belongs to the Section Innovative Cropping Systems)
Show Figures

Figure 1

11 pages, 4540 KB  
Article
New Data on the Distribution and Systematic Position of Marsupella minutissima, a Poorly Known Species from Gymnomitriaceae (Marchantiophyta)
by Vadim A. Bakalin, Seung Se Choi, Vladimir E. Fedosov, Myung-Ok Moon and Alina V. Fedorova
Plants 2024, 13(21), 3037; https://doi.org/10.3390/plants13213037 - 30 Oct 2024
Viewed by 826
Abstract
Marsupella minutissima was recorded for the first time outside of Japan in Jeju-do in the Republic of Korea. The new data significantly improve the knowledge of the species distribution. An analysis of the phylogenetic affinities of the species based on nuclear ITS and [...] Read more.
Marsupella minutissima was recorded for the first time outside of Japan in Jeju-do in the Republic of Korea. The new data significantly improve the knowledge of the species distribution. An analysis of the phylogenetic affinities of the species based on nuclear ITS and plastid trnL-trnF regions showed that it is resolved within the clade corresponding to Marsupella sect. Ustulatae, which is where the most morphologically similar M. funckii and M. sprucei are placed. These tree taxa are well delimited geographically. When found within the same region, such as a mountain chain, they occupy different altitudinal belts. Our results showed clear molecular delimitation; however, we failed to estimate the affinities of M. minutissima within the section based on the available molecular data. A description, line-art illustrations and photographs of the collected materials are provided; data on the oil bodies of the species were obtained for the first time. Full article
(This article belongs to the Section Plant Systematics, Taxonomy, Nomenclature and Classification)
Show Figures

Figure 1

14 pages, 3657 KB  
Article
Determinants of Length of Stay for Medical Inpatients Using Survival Analysis
by Jaekyeong Kim, Haegak Chang, Seiyoung Ryu, Ilyoung Choi, Angela Eunyoung Kwon and Haeyong Ji
Int. J. Environ. Res. Public Health 2024, 21(11), 1424; https://doi.org/10.3390/ijerph21111424 - 26 Oct 2024
Cited by 1 | Viewed by 2385
Abstract
With the increase in insured patients and an aging population, managing the length of stay (LOS) for inpatients has become crucial for controlling medical costs. Analyzing the factors influencing LOS is necessary for effective management. Previous studies often used multiple or logistic regression [...] Read more.
With the increase in insured patients and an aging population, managing the length of stay (LOS) for inpatients has become crucial for controlling medical costs. Analyzing the factors influencing LOS is necessary for effective management. Previous studies often used multiple or logistic regression analyses, which have limitations such as unmet assumptions and the inability to handle time-dependent variables. To address these issues, this study applied survival analysis to examine the factors affecting LOS using the National Health Insurance Service (NHIS) sample cohort data from 2016 to 2019, covering over 4 million records. We used Kaplan–Meier survival estimation to assess LOS probabilities based on sociodemographic, patient, health checkup, and institutional characteristics. Additionally, the Cox proportional hazards model controlled for confounding factors, providing more robust validation. Key findings include the influence of age, gender, type of insurance, and hospital type on LOS. For instance, older patients and medical aid recipients had longer LOS, while general hospitals showed shorter stays. This study is the first in Korea to use survival analysis with a large cohort database to identify LOS determinants. The results provide valuable insights for shaping healthcare policies aimed at optimizing inpatient care and managing hospital resources more efficiently. Full article
Show Figures

Figure 1

10 pages, 293 KB  
Article
Analysis of Dental Prosthetic Treatment in Patients with Cancer Aged 65 Years and Older after Expanded Health Insurance Coverage: A Retrospective Clinical Study
by Hyo-Jung Kim and Iel-Yong Sung
Medicina 2024, 60(9), 1509; https://doi.org/10.3390/medicina60091509 - 16 Sep 2024
Cited by 1 | Viewed by 1598
Abstract
Background and Objectives: With increases in cancer incidence and the number of cancer survivors, the demand for cancer management is growing. However, studies on dental prosthetic treatment for patients with cancer are rare. We aim to investigate the dental prosthetic treatment in [...] Read more.
Background and Objectives: With increases in cancer incidence and the number of cancer survivors, the demand for cancer management is growing. However, studies on dental prosthetic treatment for patients with cancer are rare. We aim to investigate the dental prosthetic treatment in patients with cancer aged ≥65 years after expanded health insurance coverage. Materials and Methods: This retrospective study included patients who were treated with implants and removable dentures at Ulsan University Hospital in South Korea between June 2015 and June 2023. Data on age, sex, cancer location, comorbid systemic diseases, number of remaining teeth, dental prosthetic treatment history, type of dental prosthetic treatment, and insurance coverage status were extracted from patient medical records and panoramic radiographs. The influence of multiple variables on dental prosthetic treatment was analyzed using the Chi-square and Fisher’s exact tests. Results: The study included 61 patients with cancer (32 men, 29 women; average age: 70.9 years). Among them, 56 (91.8%) had insurance coverage benefits, and 34 (55.7%) received treatments such as implants, removable partial dentures, or complete dentures for the first time. Treatment types included 37 (60.7%) cases of implant prostheses and 24 (39.3%) conventional removable dentures. No statistical differences were observed in the type of dental prosthetic treatment according to sex, age, cancer location, number of systemic diseases, and dental prosthetic treatment history (p > 0.05). Patients with <10 remaining teeth received treatment with conventional removable dentures, which was statistically significant (p < 0.001). Conclusions: Of the 61 patients, 56 (91.8%) received insurance benefits, and 34 (55.7%) underwent dental prosthetic treatment for the first time. Within the limitations of this retrospective study, the expanded health insurance coverage alleviated the unmet demand for dental prosthetic treatment. As cancer prevalence continues to increase, expanding customized health insurance coverage is crucial to meet this demand. Full article
(This article belongs to the Special Issue Boundaries Between Oral and General Health)
17 pages, 2310 KB  
Article
A Multi-Center, Open-Label, Single-Arm Study to Investigate the Early Effectiveness of Esketamine Nasal Spray in Patients with Treatment-Resistant Depression Using a Mobile Self-Monitoring Application
by Junhyung Kim, Seung-Hoon Lee, Cheolmin Shin, Kyu-Man Han, Sung Joon Cho, Narei Hong and Changsu Han
Pharmaceuticals 2024, 17(9), 1143; https://doi.org/10.3390/ph17091143 - 30 Aug 2024
Cited by 2 | Viewed by 2347
Abstract
This study assesses the early effectiveness of esketamine nasal spray (ESK) in adults with treatment-resistant depression (TRD) 1 day after the first administration, as monitored through self-assessment via the mobile application, Esketamine Continuing Assessment for Relapse Prevention (EsCARe). In this multi-center, open-label, single-arm [...] Read more.
This study assesses the early effectiveness of esketamine nasal spray (ESK) in adults with treatment-resistant depression (TRD) 1 day after the first administration, as monitored through self-assessment via the mobile application, Esketamine Continuing Assessment for Relapse Prevention (EsCARe). In this multi-center, open-label, single-arm study, adults aged 18–65 years diagnosed with TRD after failing at least two antidepressant therapies were enrolled from five tertiary hospitals in South Korea. During the induction period, participants self-administered ESK twice weekly and used the EsCARe app daily to record mood, sleep, and somatic symptoms. Key clinical assessments, the Patient Health Questionnaire-9 (PHQ-9), the Hamilton Depression Rating Scale (HAMD), and the Generalized Anxiety Disorder Scale (GAD-7), were measured at baseline and at weeks 2 and 4. The reliability and validity of EsCARe was assessed. The treatment results indicated significant improvements in depressive and anxiety symptoms, with notable reductions in the PHQ-9 and the GAD-7 by week 2, and the HAMD by week 4. The EsCARe app reliably and validly monitored depressive symptoms and demonstrated a significant reduction in depressive symptoms 1 day after the first administration of ESK. Using ESK, complemented by mobile self-monitoring, effectively reduces the symptoms of TRD early in the treatment course. Integrating mobile health technology into the therapeutic regimen highlights a significant advancement in managing TRD, offering patients and clinicians immediate feedback on treatment efficacy. Full article
Show Figures

Figure 1

13 pages, 1079 KB  
Article
Evaluation of Pepper (Capsicum spp.) Germplasm Collection for Bacterial Wilt (Ralstonia solanacearum) Resistance
by Nayoung Ro, Mesfin Haile, Hyeonseok Oh, Ho-Cheol Ko, Jungyoon Yi, Young-Wang Na and Onsook Hur
Agronomy 2024, 14(8), 1753; https://doi.org/10.3390/agronomy14081753 - 10 Aug 2024
Cited by 1 | Viewed by 1456
Abstract
This study was conducted to identify resistant pepper accessions against the destructive disease bacterial wilt (BW) caused by Ralstonia solanacearum. A total of 338 pepper (Capsicum species) germplasms collected from different countries and deposited in the National Agrobiodiversity Genebank, Rural Development Administration (RDA), [...] Read more.
This study was conducted to identify resistant pepper accessions against the destructive disease bacterial wilt (BW) caused by Ralstonia solanacearum. A total of 338 pepper (Capsicum species) germplasms collected from different countries and deposited in the National Agrobiodiversity Genebank, Rural Development Administration (RDA), Republic of Korea, were evaluated. The evaluated accessions comprise samples from five distinct species: Capsicum annuum (213), Capsicum baccatum (47), Capsicum chinense (45), Capsicum frutescens (31), and Capsicum chacoense (2). Disease severity scores were recorded over four consecutive weeks and showed an increase in severity from initial inoculation to the end of the evaluation period. A strong correlation was observed between week 1 and 2, as well as between week 3 and 4. Ten resistant pepper accessions were identified. All selected accessions consistently exhibited low disease scores ranging from 0 to 1 throughout the observation period. These accessions belong to C. chinense (2), C. annuum (6), C. chacoense (1), and C. frutescens (1). Accessions such as IT236738 (C. chinense) and IT283498 (C. chinense) were demonstrated to have high resistance, showing no symptoms over all four weeks. Other accessions belonging to C. annuum (IT247232 and IT236340) and C. chacoense (IT158713) maintained a disease score of 0 (no symptoms) for the first three consecutive weeks; however, they developed symptoms with a score of 1 in the fourth week. Other important characteristics of the resistant materials were evaluated, including carotenoids and fruit characteristics. These accessions have important traits beyond resistance to the destructive pepper disease. They will serve as promising resources for breeding resistant pepper varieties against BW to enhance productivity. Full article
(This article belongs to the Section Pest and Disease Management)
Show Figures

Figure 1

10 pages, 2610 KB  
Article
Development of Field Tests for Cardiovascular Fitness Assessment in Wheelchair
by Eun Hyung Cho, Bong-Arm Choi and Yongsuk Seo
Healthcare 2024, 12(5), 580; https://doi.org/10.3390/healthcare12050580 - 2 Mar 2024
Cited by 2 | Viewed by 2520
Abstract
It is essential to consider both physique and physical fitness factors to minimize the risk of injuries and optimize athletic performance among elite athletes. Athletes with disabilities face limitations in fitness assessments compared to their healthy counterparts. The aim of this study was [...] Read more.
It is essential to consider both physique and physical fitness factors to minimize the risk of injuries and optimize athletic performance among elite athletes. Athletes with disabilities face limitations in fitness assessments compared to their healthy counterparts. The aim of this study was to revalidate established cardiovascular fitness assessment methods and develop field tests for wheelchair athletes. As representatives registered at the Korea Paralympic Committee’s Athletes Training Center in Icheon, athletes with physical disabilities participating in para ice hockey (n = 14), who were capable of wheelchair control, were volunteered. Prior to cardiovascular fitness assessments using an ergometer and a shuttle run, demographic characteristics were surveyed, and physical measurements and muscle strength (grip strength) were recorded. All the participants performed one ergometer test based on cardiovascular fitness criteria, and for shuttle run validation, two trials were conducted using existing audio cues (National Physical Fitness 100, 20 m shuttle run). For the development of the shuttle run, considering wheelchair turning, signal-to-sound intervals were increased by 1 s and 1.5 s, respectively, in two trials. An analysis of the correlation with the maximal oxygen consumption (VO2max) in comparison to the reference criterion, an ergometer, demonstrated high correlations in the first trial (r = 0.738) and the second trial (r = 0.780). Similarly, significant correlations were observed with the maximum heart rate (HRmax) in the first trial (r = 0.689) and the second trial (r = 0.896). Thus, the 15 m shuttle run is validated as a field test for assessing cardiovascular fitness in athletes with disabilities. Correlation analysis with maximal oxygen uptake (VO2max) compared to the reference criterion, an ergometer, revealed a correlation of 0.815 with a 1 s interval audio cue and 0.355 with a 1.5 s interval audio cue. A high correlation was observed with the 1 s interval audio cue. Regarding the maximum heart rate (HRmax), the correlations were 0.665 with a 1 s interval audio cue. Once again, a high correlation was noted with the 1 s interval audio cue. The field test selected for measuring cardiovascular fitness in wheelchair athletes involved performing a 15 m shuttle run while in the wheelchair. The test utilized an audio cue with a 1 s increased interval between the signal sounds. Full article
Show Figures

Figure 1

19 pages, 1408 KB  
Article
Airport Surface Arrival and Departure Scheduling Using Extended First-Come, First-Served Scheduler
by Bae-Seon Park and Hak-Tae Lee
Aerospace 2024, 11(1), 24; https://doi.org/10.3390/aerospace11010024 - 26 Dec 2023
Cited by 3 | Viewed by 2438
Abstract
This paper demonstrates the effectiveness of the Extended First-Come, First-Served (EFCFS) scheduler for integrated arrival and departure scheduling by comparing the scheduling results with the recorded operational data at Incheon International Airport (ICN), Republic of Korea. The EFCFS scheduler can handle multiple capacity- [...] Read more.
This paper demonstrates the effectiveness of the Extended First-Come, First-Served (EFCFS) scheduler for integrated arrival and departure scheduling by comparing the scheduling results with the recorded operational data at Incheon International Airport (ICN), Republic of Korea. The EFCFS scheduler can handle multiple capacity- or flow-rate-related constraints along the path of each flight, which is represented by a node–link graph structure, and can solve large-scale problems with low computational cost. However, few studies have attempted a systematic verification of the EFCFS scheduler by comparing the scheduling results with historical operational data. In this paper, flights are scheduled between gates and runways on the airport surface with detailed constraints such as runway wake turbulence separation minima and conflict-free taxiing. The scheduler is tested using historical flight data from 15 August 2022 at ICN. The input schedule is generated based on the flight plan data extracted from the Flight Operation Information System (FOIS) and airport surface detection equipment data, and the results are compared with the times extracted from the FOIS data. The scheduling results for 500 aircraft show that the average takeoff delay is reduced by about 19 min, while the average landing delay is increased by less than one minute when the gate occupancy constraint is not considered. The results also confirm that the EFCFS effectively utilizes the available time slots to reduce delays by switching the original departure or arrival orders for a small number of flights. Full article
(This article belongs to the Section Air Traffic and Transportation)
Show Figures

Figure 1

Back to TopTop