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Updates in Digestive Diseases and Endoscopy
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Updates in Digestive Diseases and Endoscopy

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Gastroenterology & Hepatopancreatobiliary Medicine".

Deadline for manuscript submissions: 30 November 2024 | Viewed by 1124

Special Issue Editors

Dr. Hossein Haghbin

E-Mail Website
Guest Editor
Department of Gastroenterology, Ascension Providence Southfield, Southfield, MI, USA
Interests: colonoscopy; gastroenterology; endoscopy; endoscopic retrograde cholangiopancreatography
Dr. Muhammad Aziz

E-Mail Website
Guest Editor
Division of Gastroenterology, Bon Secours Mercy Health, Toledo, OH 43608, USA
Interests: colon cancer screening; colonoscopy; esophagogastroduodenoscopy; gastrointestinal hemorrhage; inflammatory bowel disease
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The advancements in endoscopy during the current era are remarkable. Various diseases that have previously been difficult to diagnose or treat have become subjects of EGD, colonoscopy, ERCP, or EUS. Surgery is being replaced by auxiliary endoscopic methods like EMR and ESD in the resection of lesions with submucosal invasion. With the ever-increasing rates of obesity across the globe, endobariatric procedures are gaining popularity due to the data exhibiting excellent efficacy and safety. Artificial intelligence and many auxiliary techniques and devices used for the increasing of adenoma detection rates and the improving of the quality of colonoscopies have been major topics of discussion in recent years. Moreover, the novel developments in cholangioscopy and pancreatoscopy have opened doors to great diagnostic and therapeutic areas. Third space endoscopic techniques like POEM have replaced surgery in the treatment of achalasia, gastroparesis, and many other diseases. These topics, in addition to any topics pertaining to endoscopy in terms of efficacy, safety, cost effectiveness, innovations, reviews, etc, are highly welcome for consideration to be published in this Special Issue.

Dr. Hossein Haghbin
Dr. Muhammad Aziz
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • colonoscopy
  • EGD
  • ERCP
  • EUS
  • endoscopic submucosal dissection (ESD)
  • endoscopic mucosal resection (EMR)
  • artificial intelligence
  • screening colonoscopy
  • pancreatoscopy
  • cholangioscopy

Published Papers (2 papers)

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14 pages, 3824 KiB  
Article
Clinical Utility of Disease Activity Indices in Predicting Short-Term Response to Biologics in Patients with Ulcerative Colitis
by Filip Romaniuk, Anna Franus, Aleksandra Sobolewska-Włodarczyk and Anita Gąsiorowska
J. Clin. Med. 2024, 13(12), 3455; https://doi.org/10.3390/jcm13123455 - 13 Jun 2024
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Abstract
Background: The Mayo Score [MS], endoscopic Mayo Score [eMS] and the Ulcerative Colitis Index of Severity [UCEIS] are employed in the assessment of ulcerative colitis [UC] severity. This study compared the aforementioned indices in terms of predictory value for response to remission [...] Read more.
Background: The Mayo Score [MS], endoscopic Mayo Score [eMS] and the Ulcerative Colitis Index of Severity [UCEIS] are employed in the assessment of ulcerative colitis [UC] severity. This study compared the aforementioned indices in terms of predictory value for response to remission induction treatment with anti-TNF and anti-integrin biologics. Methods: A total of 38 patients were retrospectively evaluated in the study, 23 male and 15 female, aged 18–74 years old who had undergone a total of 53 biological therapy courses with either infliximab [IFX] or vedolizumab [VDZ] at the Department of Gastroenterology of the Medical University of Łódź. The clinical and endoscopic activity of UC was assessed at the outset of biological therapy and the 14th week remission induction assessment juncture. Results: The study analyzed 19 IFX and 34 VDZ treatment courses. The response rate of patients receiving IFX reached 73.67% and the response rate was 58.82% for VDZ. The mean MS, eMS and UCEIS improved among all patient groups: 8.316 ± 1.974 to 4.158 ± 2.218 (p < 0.05), 2.632 ± 0.597 to 1.790 ± 0.713 (p < 0.05) and 4.790 ± 1.745 to 3.000 ± 1.453 (p < 0.05) for IFX, 7.088 ± 2.234 to 3.618 ± 2.412 (p < 0.05), 2.706 ± 0.524 to 1.677 ± 1.065 (p < 0.05) and 4.235 ± 1.350 to 2.735 ± 1.880 (p < 0.05) for VDZ. Conclusions: The outcome assessment in induction treatment of UC includes clinical data and endoscopic evaluation. Severity of inflammatory lesion activity according to the eMS and UCEIS indices correlates with the overall disease presentation as evaluated with MS. The UCEIS provides an overall better predictor for biological induction treatment when compared with the eMS in both patient groups, particularly in those receiving VDZ. It provides a promising alternative to the eMS and can be employed for both initial disease severity assessment as well as for treatment response monitoring. Full article
(This article belongs to the Special Issue Updates in Digestive Diseases and Endoscopy)
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8 pages, 5721 KiB  
Case Report
Residual Recurrence of a Small Intestinal Capillary Hemangioma with Obscure Gastrointestinal Bleeding Treated by Double-Balloon Endoscopy: A Case Report and Literature Review
by Kei Nomura, Tomoyoshi Shibuya, Arisa Yuzawa, Masashi Omori, Rina Odakura, Masao Koma, Kentaro Ito, Eiji Kamba, Takafumi Maruyama, Osamu Nomura, Hirofumi Fukushima, Takashi Murakami, Kumiko Ueda, Dai Ishikawa, Mariko Hojo and Akihito Nagahara
J. Clin. Med. 2024, 13(12), 3415; https://doi.org/10.3390/jcm13123415 - 11 Jun 2024
Viewed by 439
Abstract
An 86-year-old man presented with anemia. He underwent abdominal contrast-enhanced computed tomography, gastroscopy, and colonoscopy without any bleeding detected. Small bowel capsule endoscopy (SBCE) revealed a reddish polypoid lesion with blood oozing into the jejunum. Antegrade double-balloon endoscopy (DBE) revealed a 5 mm [...] Read more.
An 86-year-old man presented with anemia. He underwent abdominal contrast-enhanced computed tomography, gastroscopy, and colonoscopy without any bleeding detected. Small bowel capsule endoscopy (SBCE) revealed a reddish polypoid lesion with blood oozing into the jejunum. Antegrade double-balloon endoscopy (DBE) revealed a 5 mm sized protrusion into the jejunum. Endoscopic mucosal resection (EMR) was difficult; the lesion was snared and resected before energization. Clips prevented further bleeding and the lesion’s position was marked with a tattoo. Histopathological examination of the lesion led to a diagnosis of capillary hemangioma. After 11 months, the patient was again anemic. A reddish polypoid lesion oozing blood near the tattoo was found by SBCE. Another antegrade DBE showed a 7 mm sized protrusion near the tattoo. The lesion was successfully treated by EMR. Histopathological examination revealed the residual recurrence of a small intestinal capillary hemangioma. The patient recovered from anemia after the EMR. Two months later, SBCE showed no findings around the tattoo. Hemangiomas account for 7–10% of benign small intestinal tumors; most are cavernous hemangiomas, and capillary hemangiomas are rare. We report a rare case of a recurring small intestinal capillary hemangioma detected by SBCE and treated using DBE. We also review the literature. Full article
(This article belongs to the Special Issue Updates in Digestive Diseases and Endoscopy)
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