Background: Breast mass is one of the main symptoms of breast cancer. Effective and accurate detection of breast masses at an early stage would be of great value for clinical breast cancer analysis. Methods: We developed a novel mass detection framew...
Co-infections pose significant challenges not only clinically, but also in terms of simultaneous diagnoses. The development of sensitive, multiplexed analytical platforms is critical for accurately detecting viral co-infections, particularly in compl...
In recent years, computer vision technology has been widely used in the field of medical image processing. However, there is still a big gap between the existing breast mass detection methods and the real-world application due to the limited detectio...
Application of computer vision and robotics in agriculture requires sufficient knowledge and understanding of the physical properties of the object of interest. Yield monitoring is an example where these properties affect the quantified estimation of...
One-dimensional nanobeam mass sensors offer an unprecedented ability to measure tiny masses or even the mass of individual molecules or atoms, enabling many interesting applications in the fields of mass spectrometry and atomic physics. However, curr...
Radar measurements of gravitational mass-movements like snow avalanches have become increasingly important for scientific flow observations, real-time detection and monitoring. Independence of visibility is a main advantage for rapid and reliable det...
Shotgun proteomics has proven to be an attractive alternative for identifying a pathogen and characterizing the antimicrobial resistance genes it produces. Because of its performance, proteotyping of microorganisms by tandem mass spectrometry is expe...
In respect of rock-mass engineering, the detection of planar structures from the rock-mass point clouds plays a crucial role in the construction of a lightweight numerical model, while the establishment of high-quality models relies on the accurate r...
In this paper, we release a new large-scale dataset containing multiple categories of ships and floating objects at sea, which we call MASS-LSVD. It is used to train and validate target detection algorithms and future large models for ship autopiloti...
In consideration of the presented optical-thermally excited resonant mass detection scheme, molecular dynamics calculations are performed to investigate the thermal actuation and resonant mass sensing mechanism. The simulation results indicate that a...
4 September 2012
Endocrine disrupting chemicals, among them many pesticides, alter the normal functioning of the endocrine system of both wildlife and humans at very low concentration levels. Therefore, the importance of method development for their analysis in food...
The deviation of the center of mass of a gravitational wave detection satellite from its calibrated position can severely impact the accuracy of gravitational wave detection. Therefore, there is an urgent need to develop effective identification meth...
The detection of exceedingly small masses still presents a large challenge, and even though very high sensitivities have been archived, the fabrication of those setups is still difficult. In this paper, a novel approach for a co-resonant mass detecto...
Computer-aided detection (CADe) of masses in digital breast tomosynthesis (DBT) is crucial for early breast cancer diagnosis. However, the variability in the size and morphology of breast masses and their resemblance to surrounding tissues present si...
Space-based gravitational wave detection imposes extremely high requirements on displacement measurement accuracy, with its core measurement components being laser interferometers and inertial sensors. The laser interferometers detect gravitational w...
Natural toxins include a wide range of toxic metabolites also occurring in food and products, thus representing a risk for consumer health. In the last few decades, several robust and sensitive analytical methods able to determine their occurrence in...
In this paper a new theoretical model is derived, the results of which permit a detailed examination of how the resonant characteristics of a cantilever are influenced by a particle (adsorbate) attached at an arbitrary position along the beam’s lengt...
The marketing of poultry livers is only authorized as fresh, frozen, or deep-frozen. The higher consumer demand for these products for a short period of time may lead to the marketing of frozen–thawed poultry livers: this constitutes fraud. The aim o...
A portable mass spectrometer (PMS) was combined with a mesoporous silica material (SBA-15) coated solid-phase microextraction (SPME) Arrow to develop a rapid, easy-to-operate and sensitive method for detecting five veterinary drugs—amantadine,...
11 August 2016
Exposure to malachite green (MG) may pose great health risks to humans; thus, it is of prime importance to develop fast and robust methods to quantitatively screen the presence of malachite green in water. Herein the application of extractive electro...
Food allergy is a growing global health concern, with seafood representing one of the most significant sources of allergic reactions. The primary allergens responsible for fish and shellfish allergies are β-parvalbumins and tropomyosin, respecti...
Food poisoning caused by Staphylococcal enterotoxins (SEs) is prevalent globally, making efficient detection of these toxins very important. Traditionally, liquid chromatography–mass spectrometry required immunosorbent enrichment by magnetic be...
Despite surpassing lung cancer as the most frequently diagnosed cancer, female breast cancer (BC) still lacks rapid detection methods for screening that can be implemented on a large scale in practical clinical settings. However, urine is a readily a...
Fast and reliable information is crucial for first responders to draw correct conclusions at crime scenes. An ambient pressure laser desorption (APLD) mass spectrometer is introduced for this scenario, which enables detecting substances on surfaces w...
Vibrating micro- and nanomechanical mass sensors are capable of quantitatively determining attached mass from only the first three (two) measured cantilever (suspended) resonant frequencies. However, in aqueous solutions that are relevant to most bio...
Structures vibrate with their natural frequencies when disturbed from their equilibrium position. These frequencies reduce when an additional mass accumulates on their structures, like ice accumulation on wind turbines installed in cold climate sites...
The chromatographic resolution of pregabalin enantiomers has been often achieved by derivatization of the molecule, in order to reach enough sensitivity at low concentrations of the minor enantiomer present in the active principle. In the present art...
The paper describes the original results of a comparative study of the standard seismic station vs. a novel interferometric sensor for civil engineering needs. The presented results showed that to implement seismic measurements using standard seismic...
Elastic wave tomography is a non-destructive technique used to obtain velocity images of internal structures. Wave velocity tomography has been used to quantitatively describe abnormal structures and identify boundaries in different media and shapes....
Ship emissions are a major cause of global air pollution, and in particular, emissions from the combustion of bunker fuels, such as heavy fuel oil (HFO), show strong impacts on the environment and human health. Therefore, sophisticated measurement te...
Phenolic compounds are abundant secondary metabolites in plums, with potential health benefits believed to be due to their antioxidant activity, amongst others. Phenolic characterisation of South African Prunus salicina Lindl. plums is necessary to f...
The development of healthier and more sustainable food products, such as plant-based meat substitutes (PBMSs), have received significant interest in recent years. A thorough understanding of the aroma composition can support efforts to improve the se...
We propose a method for effectively utilizing weakly annotated image data in an object detection tasks of breast ultrasound images. Given the problem setting where a small, strongly annotated dataset and a large, weakly annotated dataset with no boun...
Plastic particles smaller than 5 mm accumulate in aqueous, terrestrial, and atmospheric environments and their discovery has been a serious concern when it comes to eco-toxicology and human health risk assessment. In the following review, the potenti...
Core-collapse supernovae (SNe) are one of the most powerful cosmic sources of neutrinos, with energies of several MeV. The emission of neutrinos and antineutrinos of all flavors carries away the gravitational binding energy of the compact remnant and...
Purpose: The p53 protein and its post-translational modifications are distinctly expressed in various normal cell types and malignant cells and are usually detected by immunohistochemistry and flow cytometry in contemporary diagnostics. Here, we desc...
In this study, new approaches are proposed over a range of conditions with unknown loading time to determine the initial conditions and identify the explicit model parameters of successive weighing system in the early part of the transient response....
Detection of ultrasmall masses such as proteins and pathogens has been made possible as a result of advancements in nanotechnology. Development of label-free and highly sensitive biosensors has enabled the transduction of molecular recognition into d...
This work demonstrates the improvement of mass detection sensitivity and time response using a simple sensor structure. Indeed, complicated technological processes leading to very brittle sensing structures are often required to reach high sensitivit...
Mass spectrometry is a key analytical platform for metabolomics. The precise quantification and identification of small molecules is a prerequisite for elucidating the metabolism and the detection, validation, and evaluation of isotope clusters in LC...
This study aimed to optimize and validate a multi-residue method for identifying and quantifying pesticides in honey by using both gas and liquid chromatographic separation followed by mass spectrometric detection. The proposed method was validated t...
Mass spectrometry has recently become a powerful technique for bacterial identification. Mass spectrometry approaches generally rely upon introduction of the bacteria into a matrix-assisted laser-desorption time-of-flight (MALDI-TOF) mass spectromete...
Determining gas compositions from live well fluids on a drilling rig is critical for real time formation evaluation. Development and utilization of a reliable mass spectrometric method to accurately characterize these live well fluids are always chal...
30 September 2013
The identification of metabolites in drug discovery is important. At present, radioisotopes and mass spectrometry are both widely used. However, rapid and comprehensive identification is still laborious and difficult. In this study, we developed ne...
Characterizing the surface deformation during the inter-survey period could assist in understanding rock mass progressive failure processes. Moreover, 3D reconstruction of rock mass surface is a crucial step in surface deformation detection. This stu...
Advancements in microfabrication technologies and novel materials have led to new innovations in miniaturized gas sensors that can identify miniscule changes in a complex environment. Micromachined resonators with the capability to offer high sensiti...
Antimicrobial and immunomodulatory peptides (AMPs) are considered as the key players in the maintenance of skin barrier functions. Here, we developed a novel approach for the examination of AMPs in the outermost layer of the epidermis, namely stratum...
Liquid-borne particles sampling and cantilever-based mass detection are widely applied in many industrial and scientific fields e.g., in the detection of physical, chemical, and biological particles, and disease diagnostics, etc. Microscopic analysis...
A single-molecule detection method was developed for nucleic acids based on mass spectrometry counting single liposome particles. Before the appearance of symptoms, a negligible amount of nucleic acids and biomarkers for the clinical diagnosis of the...
T-2 toxin is a mycotoxin routinely found as a contaminant of cereal grains worldwide. A portable mass spectrometer was adapted to enable the detection of T-2 toxin in wheat and maize by APCI-MS. In order to facilitate rapid testing, a rapid cleanup w...
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