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5,521 Results Found

  • Feature Paper
  • Review
  • Open Access
84 Citations
19,317 Views
35 Pages

An Overview of the Molecular Mechanisms Associated with Myocardial Ischemic Injury: State of the Art and Translational Perspectives

  • Leonardo Schirone,
  • Maurizio Forte,
  • Luca D’Ambrosio,
  • Valentina Valenti,
  • Daniele Vecchio,
  • Sonia Schiavon,
  • Giulia Spinosa,
  • Gianmarco Sarto,
  • Vincenzo Petrozza and
  • Sebastiano Sciarretta
  • + 1 author

30 March 2022

Cardiovascular disease is the leading cause of death in western countries. Among cardiovascular diseases, myocardial infarction represents a life-threatening condition predisposing to the development of heart failure. In recent decades, much effort h...

  • Article
  • Open Access
11 Citations
4,549 Views
31 Pages

10 March 2023

Fine art coating is usually created by the combination of metal filler and water-based coatings, decorated to the surface of wood structures, furniture, and crafts. However, the durability of the fine art coating is limited by its weak mechanical qua...

  • Article
  • Open Access
10 Citations
3,567 Views
33 Pages

An Artwork Rental System Based on Blockchain Technology

  • Der-Chen Huang,
  • Ling-Chun Liu,
  • Yong-Yuan Deng and
  • Chin-Ling Chen

26 January 2023

In recent years, due to the slowdown of the global economy and the instability of the stock market and real estate market, the art market has gradually become the third-largest investment market after the former two. As more and more funds flow into...

  • Article
  • Open Access
2 Citations
5,077 Views
15 Pages

It is often assumed that in the collapse of the Aristotelian distinction between art and nature that results from the rise of mechanical philosophies in the early modern period, the collapse falls on the side of art. That is, all of the diversity amo...

  • Article
  • Open Access
1 Citations
2,723 Views
20 Pages

Art Nouveau Buildings, Examples of Innovative and Sustainable Approach—Case Study: Oradea, Romania

  • Mariana Ratiu,
  • Emil Traian Gligor,
  • George Florentin Tamas,
  • Ana Cornelia Peres and
  • Mircea Bogdan Tataru

28 June 2025

In the current context, where sustainability, energy efficiency, and reduction of environmental impact are omnipresent themes, the need and interest for conservation, restoration, and reuse of heritage buildings is a topic of real interest. The city...

  • Review
  • Open Access
124 Citations
8,720 Views
29 Pages

20 August 2021

Mechanical properties and data analysis for the prediction of different mechanical properties of geopolymer concrete (GPC) were investigated. A relatively large amount of test data from 126 past works was collected, analyzed, and correlation between...

  • Review
  • Open Access
225 Views
22 Pages

Endometriosis at the Single-Cell Level: Molecular Insights and Implications for Assisted Reproduction Success

  • Angeliki Gerede,
  • Efthymios Oikonomou,
  • Foteini Gkaitatzi,
  • Maria Danavasi,
  • Panayiota Papasozomenou,
  • Anastasios Potiris,
  • Sofoklis Stavros,
  • Vasiliki Kourti,
  • Aikaterini Domali and
  • Menelaos Zafrakas
  • + 1 author

9 March 2026

Endometriosis is a chronic hormone-responsive disorder linked to infertility, usually characterized by the presence of ectopic endometrium in the pelvis that disrupts local homeostasis. Advances in single-cell “omic” methods have revealed...

  • Proceeding Paper
  • Open Access
405 Views
9 Pages

26 December 2025

In agricultural workplaces, upper-body strain arises not only from lifting and carrying harvest crates but also from pushing, pulling, twisting, and squatting motions. Drawing inspiration from the momentary shoulder contraction and whole-body coordin...

  • Article
  • Open Access
1 Citations
2,042 Views
38 Pages

25 February 2025

This study introduces and examines the principle of accentuation as a novel mechanism in perceptual organization, analyzing its effects through the framework of Grossberg’s Adaptive Resonance Theory (ART). We demonstrate that localized accentua...

  • Feature Paper
  • Article
  • Open Access
8 Citations
3,433 Views
16 Pages

Talking about dying, death, and loss may be difficult. Arts offer alternative ways of engaging with end-of-life (EoL) issues, but little is known about the means through which this occurs. In this article, we aim to explore mechanisms in arts activit...

  • Review
  • Open Access
17 Citations
6,745 Views
17 Pages

Epigenetic Mechanisms of ART-Related Imprinting Disorders: Lessons From iPSC and Mouse Models

  • Alex Horánszky,
  • Jessica L. Becker,
  • Melinda Zana,
  • Anne C. Ferguson-Smith and
  • András Dinnyés

26 October 2021

The rising frequency of ART-conceived births is accompanied by the need for an improved understanding of the implications of ART on gametes and embryos. Increasing evidence from mouse models and human epidemiological data suggests that ART procedures...

  • Article
  • Open Access
4,571 Views
22 Pages

14 August 2025

This research presents a generative AI mechanism designed to assist artists in finding inspiration and developing ideas during their creative process by leveraging their emotions as a driving force. The proposed iterative inspiration cycle, complete...

  • Article
  • Open Access
23 Citations
3,418 Views
13 Pages

Thymic Exhaustion and Increased Immune Activation Are the Main Mechanisms Involved in Impaired Immunological Recovery of HIV-Positive Patients under ART

  • Maria Carolina Dos Santos Guedes,
  • Wlisses Henrique Veloso Carvalho-Silva,
  • José Leandro Andrade-Santos,
  • Maria Carolina Accioly Brelaz-de-Castro,
  • Fabrício Oliveira Souto and
  • Rafael Lima Guimarães

5 February 2023

Decades of studies in antiretroviral therapy (ART) have passed, and the mechanisms that determine impaired immunological recovery in HIV-positive patients receiving ART have not been completely elucidated yet. Thus, T-lymphocytes immunophenotyping an...

  • Feature Paper
  • Review
  • Open Access
2 Citations
6,678 Views
12 Pages

Durable Continuous-Flow Mechanical Circulatory Support: State of the Art

  • Antonio Loforte,
  • Luca Botta,
  • Silvia Boschi,
  • Gregorio Gliozzi,
  • Giulio Giovanni Cavalli,
  • Carlo Mariani,
  • Sofia Martin Suarez and
  • Davide Pacini

12 February 2021

Implantable mechanical circulatory support (MCS) systems for ventricular assist device (VAD) therapy have emerged as an important strategy due to a shortage of donor organs for heart transplantation. A growing number of patients are receiving permane...

  • Review
  • Open Access
8 Citations
4,442 Views
48 Pages

Somatostatin, a somatotropin release inhibiting factor (SST, SRIF), is a widely distributed multifunctional cyclic peptide and acts through a transmembrane G protein-coupled receptor (SST1-SST5). Over the past decades, research has begun to reveal th...

  • Review
  • Open Access
398 Views
19 Pages

4 February 2026

This paper provides a systematic review of urushiol-based antibacterial coatings for lacquer art applications, focusing on three key dimensions: molecular mechanisms, durability, and safety. Natural lacquer films form a dense three-dimensional networ...

  • Review
  • Open Access
48 Citations
7,692 Views
25 Pages

Herbaceous Oil Crops, a Review on Mechanical Harvesting State of the Art

  • Luigi Pari,
  • Francesco Latterini and
  • Walter Stefanoni

The sustainable production of renewable energy is a key topic on the European community’s agenda in the next decades. The use of residuals from agriculture could not be enough to meet the growing demand for energy, and the contribution of veget...

  • Review
  • Open Access
76 Citations
16,103 Views
30 Pages

FRP-Reinforced/Strengthened Concrete: State-of-the-Art Review on Durability and Mechanical Effects

  • Jesús D. Ortiz,
  • Seyed Saman Khedmatgozar Dolati,
  • Pranit Malla,
  • Antonio Nanni and
  • Armin Mehrabi

28 February 2023

Fiber-reinforced polymer (FRP) composites have gained increasing recognition and application in the field of civil engineering in recent decades due to their notable mechanical properties and chemical resistance. However, FRP composites may also be a...

  • Article
  • Open Access
6 Citations
4,108 Views
9 Pages

An Investigation of Knee Injury Profiles among Iranian Elite Karatekas: Observations from a Cross-Sectional Study

  • Hamidreza Naserpour,
  • Julien S. Baker,
  • Amir Letafatkar,
  • Giacomo Rossettini and
  • Frédéric Dutheil

Karate training, despite the many positive health benefits, carries a risk of injury for participants. The current cross-sectional study aimed to investigate knee injury profiles among Iranian elite karatekas. Participants who attended the national t...

  • Review
  • Open Access
24 Citations
5,978 Views
23 Pages

19 August 2021

Earthen architecture has a significant share in the world’s fund of both residential architecture and cultural heritage. It provides a home to more than half of the world’s population and can be found in seismically active areas. Empirically acquired...

  • Article
  • Open Access
1 Citations
2,117 Views
20 Pages

14 March 2025

For some time now, regardless of the still-common paradigm of Barbour’s practice of science–religion relations, proposals have been emerging to develop a theology of science from a Christian perspective. This article begins by discussing...

  • Article
  • Open Access
1,140 Views
14 Pages

6 November 2025

This article—addressed to students, parents, teachers, and administrators alike—argues that the close study of creation is not optional to any authentic form of education, most especially the Catholic Liberal Arts tradition. Such a study,...

  • Article
  • Open Access
363 Views
17 Pages

Research Trends in Thermal Surveys and Thermomechanical Modeling of Landslides

  • Jawad Niaz,
  • Gianvito Scaringi,
  • Cosimo Cagnazzo,
  • Mario Parise and
  • Piernicola Lollino

28 January 2026

Landslides are complex geological phenomena that pose significant hazards to human life, infrastructure, and the environment. Understanding their mechanisms requires reliable data and advanced analytical methods. Thermal surveys offer valuable insigh...

  • Review
  • Open Access
1 Citations
2,478 Views
39 Pages

Parkinson’s Spectrum Mechanisms in Pregnancy: Exploring Hypothetical Scenarios for MSA in the Era of ART

  • Dalibor Kovacevic,
  • Gordana Velikic,
  • Dusan M. Maric,
  • Dusica L. Maric,
  • Miljan Puletic,
  • Ljiljana Gvozdenovic,
  • Danilo Vojvodic and
  • Gordana Supic

Multiple System Atrophy (MSA) is a rare, rapidly progressive neurodegenerative disorder marked by autonomic dysfunction, parkinsonism, and cerebellar ataxia. While predominantly affecting individuals in their fifth or sixth decade, advancements in as...

  • Article
  • Open Access
60 Citations
9,893 Views
28 Pages

Incentive Mechanisms for Smart Grid: State of the Art, Challenges, Open Issues, Future Directions

  • Sweta Bhattacharya,
  • Rajeswari Chengoden,
  • Gautam Srivastava,
  • Mamoun Alazab,
  • Abdul Rehman Javed,
  • Nancy Victor,
  • Praveen Kumar Reddy Maddikunta and
  • Thippa Reddy Gadekallu

Smart grids (SG) are electricity grids that communicate with each other, provide reliable information, and enable administrators to operate energy supplies across the country, ensuring optimized reliability and efficiency. The smart grid contains sen...

  • Review
  • Open Access
100 Citations
16,423 Views
17 Pages

Oxygen–Ozone Therapy in the Rehabilitation Field:State of the Art on Mechanisms of Action, Safety andEffectiveness in Patients with Musculoskeletal Disorders

  • Alessandro de Sire,
  • Francesco Agostini,
  • Lorenzo Lippi,
  • Massimiliano Mangone,
  • Simone Marchese,
  • Carlo Cisari,
  • Andrea Bernetti and
  • Marco Invernizzi

26 February 2021

In recent years, the interest in oxygen–ozone (O2O3) therapy application has considerably increased in the field of rehabilitation. Despite its widespread use in common clinical practice, the biochemical effects of O2O3 are still far from being under...

  • Article
  • Open Access
9 Citations
6,226 Views
20 Pages

24 January 2019

With the arrival of the era of the creative economy, the “creative community”, a joint product of the regional/community revival movement and the localization of cultural and creative industries, has become a new goal of sustainable urban...

  • Review
  • Open Access
1 Citations
2,406 Views
73 Pages

30 October 2025

Blast damage to structural members poses serious risks to both buildings and people, making it important to understand how these elements behave under extreme loads. Columns in reinforced concrete (RC) structures are especially critical, as their sud...

  • Review
  • Open Access
23 Citations
13,547 Views
37 Pages

Buckling Mechanism of Offshore Pipelines: A State of the Art

  • Debtanu Seth,
  • Bappaditya Manna,
  • Jagdish Telangrao Shahu,
  • Tiago Fazeres-Ferradosa,
  • Francisco Taveira Pinto and
  • Paulo Jorge Rosa-Santos

1 October 2021

The buckling analysis of an offshore pipeline refers to the analysis of temperature-induced uplift and lateral buckling of pipelines by analytical, numerical, and experimental means. Thus, the current study discusses different research performed on t...

  • Review
  • Open Access
29 Citations
17,259 Views
27 Pages

2 February 2024

The global surge in environmental pollution, largely attributed to industrialization, has fueled a pressing need for sustainable solutions. In response, the construction sector is increasingly focusing on bio-based materials such as hemp, recognized...

  • Review
  • Open Access
53 Citations
31,201 Views
43 Pages

Lithium Battery Degradation and Failure Mechanisms: A State-of-the-Art Review

  • Joselyn Stephane Menye,
  • Mamadou-Baïlo Camara and
  • Brayima Dakyo

14 January 2025

This paper provides a comprehensive analysis of the lithium battery degradation mechanisms and failure modes. It discusses these issues in a general context and then focuses on various families or material types used in the batteries, particularly in...

  • Review
  • Open Access
16 Citations
9,670 Views
15 Pages

25 November 2022

Metal allergy is mainly an environmental disorder which can cause allergic contact dermatitis. Environmental metal exposures include jewelry, everyday metal items, mobile phones, leather, metal-rich food and implants, including stents or anchors. Whi...

  • Review
  • Open Access
11 Citations
3,194 Views
19 Pages

A State-of-the-Art Review on the Study of the Diffusion Mechanism of Fissure Grouting

  • Xueming Du,
  • Zhihui Li,
  • Hongyuan Fang,
  • Bin Li,
  • Xiaohua Zhao,
  • Kejie Zhai,
  • Binghan Xue and
  • Shanyong Wang

18 March 2024

China is renowned for its extensive underground engineering projects and the complex geological and hydrological conditions it faces. Grouting treatment technology is widely employed in deep-buried mines and tunnels, where grouting parameters such as...

  • Review
  • Open Access
11 Citations
3,942 Views
12 Pages

7 January 2021

Many bacterial pathogens utilize ADP-ribosyltransferases (ARTs) as virulence factors. The critical aspect of ARTs is their target specificity. Each individual ART modifies a specific residue of its substrates, which could be proteins, DNA, or antibio...

  • Review
  • Open Access
3,601 Views
14 Pages

11 July 2024

ADP-ribosylation is a ubiquitous modification of proteins and other targets, such as nucleic acids, that regulates various cellular functions in all kingdoms of life. Furthermore, these ADP-ribosyltransferases (ARTs) modify a variety of substrates an...

  • Review
  • Open Access
104 Citations
17,789 Views
17 Pages

State-of-the-Art Dermatophyte Infections: Epidemiology Aspects, Pathophysiology, and Resistance Mechanisms

  • Nilce M. Martinez-Rossi,
  • Nalu T. A. Peres,
  • Tamires A. Bitencourt,
  • Maíra P. Martins and
  • Antonio Rossi

3 August 2021

The burden of fungal infections is not widely appreciated. Although these infections are responsible for over one million deaths annually, it is estimated that one billion people are affected by severe fungal diseases. Mycoses of nails and skin, prim...

  • Article
  • Open Access
15 Citations
15,686 Views
23 Pages

17 November 2009

Continuous fibre reinforced composites are now firmly established engineering materials for the manufacture of components in the automotive and aerospace industries. In this respect, composite fabrics provide flexibility in the design manufacture. Th...

  • Review
  • Open Access
51 Citations
9,993 Views
23 Pages

6 September 2022

Cancer treatment with ionizing radiation (IR) is a well-established and effective clinical method to fight different types of tumors and is a palliative treatment to cure metastatic stages. Approximately half of all cancer patients undergo radiothera...

  • Perspective
  • Open Access
6 Citations
2,367 Views
12 Pages

27 February 2023

Future European strategies to reduce dependence on foreign markets for energy supply and energy production will rely on the further exploitation of the primary sector. Lignocellulosic feedstock for bioenergy production is a valuable candidate, and de...

  • Abstract
  • Open Access
848 Views
2 Pages

Bridges are important structures, often playing a vital role in society, connecting communities, enabling easy access over complex terrains and providing aesthetic purpose. Bridges are therefore infrastructurally, socially and psychologically benefic...

  • Article
  • Open Access
1 Citations
2,407 Views
11 Pages

18 September 2021

Artemisinin (ART) is a sesquiterpene lactone and a popular malaria drug with potential anticancer properties. In this work, LC/TOF/MS, was used to investigate the reaction of ART with DNA bases. ART-deoxyadenosine and ART-deoxycytidine interactions,...

  • Review
  • Open Access
129 Views
5 Pages

Assisted Reproduction: A Novel Cardiovascular Risk Factor

  • Emrush Rexhaj,
  • Stefano F. Rimoldi,
  • Elisa Bouillet,
  • David Cerny,
  • Rodrigo Soria,
  • Robert Von Arx,
  • Yves Allemann,
  • Claudio Sartori and
  • Urs Scherrer

There is abundant evidence indicating that pathological events during early life predispose to cardiovascular and metabolic diseases later in life. Recent evidence suggests that assisted reproductive technologies (ART) represent a novel important exa...

  • Article
  • Open Access
10 Citations
2,824 Views
16 Pages

21 November 2023

Intestinal inflammation is a key determinant of intestinal and systemic health, and when our intestines are damaged, there is disruption of the intestinal barrier, which in turn induces a systemic inflammatory response. However, the etiology and path...

  • Article
  • Open Access
2 Citations
6,123 Views
14 Pages

18 October 2020

For the last two decades, the international auction houses Sotheby’s and Christie’s have been at the forefront of global art market expansion. Their world-wide footprints have enabled auction house specialists to engage with emerging arti...

  • Feature Paper
  • Review
  • Open Access
19 Citations
10,733 Views
9 Pages

Universal Connection through Art: Role of Mirror Neurons in Art Production and Reception

  • Bartlomiej Piechowski-Jozwiak,
  • François Boller and
  • Julien Bogousslavsky

Art is defined as expression or application of human creative skill and imagination producing works to be appreciated primarily for their aesthetic value or emotional power. This definition encompasses two very important elements—the creation and rec...

  • Review
  • Open Access
32 Citations
5,982 Views
27 Pages

Mechanical Properties, Durability, and Structural Applications of Rubber Concrete: A State-of-the-Art-Review

  • Shaohua He,
  • Zheng Jiang,
  • Huanwei Chen,
  • Zhiliang Chen,
  • Jianming Ding,
  • Haidong Deng and
  • Ayman S. Mosallam

24 May 2023

Substituting rubber particles for a portion of the standard coarse aggregates in concrete is regarded as a sustainable solution for tackling the issue of waste-tires disposal. In order to assess the structural performance of rubber concrete (RC), man...

  • Feature Paper
  • Review
  • Open Access
13 Citations
5,904 Views
31 Pages

As a result of the exponential growth in the production of plastics and their extended degradation period, strong environmental concerns in association with the disposal of plastic waste have emerged. Pursuing sustainable solutions for managing plast...

  • Review
  • Open Access
102 Citations
23,348 Views
24 Pages

Mechanical and Durability Performance of Coconut Fiber Reinforced Concrete: A State-of-the-Art Review

  • Jawad Ahmad,
  • Ali Majdi,
  • Amin Al-Fakih,
  • Ahmed Farouk Deifalla,
  • Fadi Althoey,
  • Mohamed Hechmi El Ouni and
  • Mohammed A. El-Shorbagy

18 May 2022

The push for sustainability in the construction sector has demanded the use of increasingly renewable resources. These natural fibers are biodegradable and non-toxic, and their mechanical capabilities are superior to those of synthetic fibers in term...

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