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13 pages, 5650 KB  
Article
Coaxial Wire Feeding-Friction Stir Additive Manufacturing
by Mengmeng Liu, Rui Wang, Xiaohu Zhu, Ximing Cheng and Songmo Li
Crystals 2025, 15(9), 784; https://doi.org/10.3390/cryst15090784 - 31 Aug 2025
Viewed by 355
Abstract
At present, most studies in the field of Wire-Friction Stir Additive Manufacturing (W-FSAM) adopt the side wire feeding method. However, the side wire feeding method has problems in that the wire feeding tube occupies working space and the tool is prone to clogging. [...] Read more.
At present, most studies in the field of Wire-Friction Stir Additive Manufacturing (W-FSAM) adopt the side wire feeding method. However, the side wire feeding method has problems in that the wire feeding tube occupies working space and the tool is prone to clogging. To address this, this study proposes a Coaxial Wire Feeding-Friction Stir Additive Manufacturing (CWF-FSAM) method. The CWF-FSAM device adopts a structure where a fixed shaft is coaxially nested inside the stirring shaft, and the fixed shaft is machined with through-channels along the circumferential direction for wire feeding, which eliminates the limitation of the wire feeding tube. This study elaborates on the structure of the CWF-FSAM device, then uses 6061 aluminum alloy as the deposition material for additive manufacturing, and conducts characterization and analysis on the microstructure and mechanical properties of the deposited components. The results show that the interlayer bonding of the deposited components is dense without defects. The components exhibit uniform and fine equiaxed grains, with the average grain sizes of the top, middle, and bottom parts being 3.52 µm, 3.35 µm, and 4.07 µm, respectively. In terms of mechanical properties, the tensile strengths of the components along the building direction (BD) and longitudinal direction (LD) both reach 70% of that of the base material (BM) wire. The hardness ranges from 36 HV to 42 HV. In addition, closed-loop components were prepared by continuous counterclockwise deposition using the CWF-FSAM device. The tensile strengths of the overlapping area, straight section, and corner were 124.45 MPa, 125.88 MPa, and 126.95 MPa, respectively. The overall performance of the closed-loop components is uniform and stable, which indicates that the CWF-FSAM-deposited components have good mechanical property isotropy. Full article
(This article belongs to the Special Issue Advanced Welding and Additive Manufacturing)
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18 pages, 7102 KB  
Article
Experimental Investigation on the Effects of POE Oil and Iron Powder on the Corrosion of TP2 Copper Tubes in Acetic Acid Vapors
by Jing Zhang, Changzheng Li, Yunlong Ou, Guofeng Su, Wenzhong Mi and Ming Fu
Appl. Sci. 2025, 15(16), 9224; https://doi.org/10.3390/app15169224 - 21 Aug 2025
Viewed by 382
Abstract
The incidence of fire accidents resulting from refrigerant leaking following the rupture of air conditioning condenser tubes has escalated in recent years. Corrosion from carboxylic acid is a primary cause in the rupture of copper tubes. The influence of lubricating oil and iron [...] Read more.
The incidence of fire accidents resulting from refrigerant leaking following the rupture of air conditioning condenser tubes has escalated in recent years. Corrosion from carboxylic acid is a primary cause in the rupture of copper tubes. The influence of lubricating oil and iron filings generated by the wear of air conditioning compressors on the corrosion of condenser copper tubes is rarely mentioned in the existing research. In order to simulate the environmental conditions inside the air conditioning unit, this study utilizes acetic acid vapor to corrode copper tubes and explores the effects of lubricating oil and iron powder on copper tube corrosion. The results demonstrate that copper corrosion follows a dendritic corrosion pattern, achieving a maximum depth of 51 μm after 28 days in 1% acetic acid vapor. A small amount of copper hydroxy acetate appears in the early stage. Copper hydroxy acetic and basic carbonate copper are converted into acetic acid copper hydrate as the acetic acid vapor increases over time. The ultimate products appear as turquoise-blue crystals. POE lubricant diminishes the corrosion rate by establishing an oil layer barrier that mitigates the volatilization of acetic acid. Iron powder preferentially reacts with acetic acid to initially protect the copper tube. The Fe3+ produced oxidizes the copper in acetic acid, hence the concentration of copper acetate rises, which facilitates the crystallization of copper acetate. Full article
(This article belongs to the Special Issue Advances in Fire Safety Engineering and Applications)
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17 pages, 3198 KB  
Article
Enhancing Pollinator Support: Plant–Pollinator Dynamics Between Salvia yangii and Anthidium Bees in Anthropogenic Landscapes
by Daniela Lupi, Claudia Giuliani, Gelsomina Fico, Serena Malabusini, Carla Sorvillo and Manuela Giovanetti
Biology 2025, 14(8), 1084; https://doi.org/10.3390/biology14081084 - 19 Aug 2025
Viewed by 596
Abstract
Anthropogenic environments are increasingly recognised for their potential to support pollinator diversity, especially through the strategic selection of ornamental plant species. This study investigated the ecological role of Salvia yangii (formerly Perovskia atriplicifolia) in supporting solitary bees, particularly species of the genus [...] Read more.
Anthropogenic environments are increasingly recognised for their potential to support pollinator diversity, especially through the strategic selection of ornamental plant species. This study investigated the ecological role of Salvia yangii (formerly Perovskia atriplicifolia) in supporting solitary bees, particularly species of the genus Anthidium, within urban green spaces in Milan (Italy). Field observations were conducted in both urban and rural sites to assess pollinator visitation rates, bee abundance, and plant traits relevant to nesting and foraging. S. yangii attracted a diverse assemblage of bee genera, with Anthidium spp. consistently recorded as dominant visitors. This preference is likely driven by the short corolla tube, which facilitates the access to nectar, and its dense coverage of trichomes, which may serve as essential nesting materials. The interaction was found to be stable across environments, suggesting that S. yangii provides reliable floral and structural resources. These findings highlight the potential of specific ornamental plants to contribute meaningfully to urban pollinator conservation. While the use of exotic species warrants caution, we propose that S. yangii may be suitable for inclusion in pollinator-friendly planting guidelines under controlled horticultural conditions, offering a promising model for enhancing urban biodiversity through informed plant selection. Full article
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16 pages, 773 KB  
Article
Barriers to Timely Referral of Children Born with Myelomeningocele in Zambia
by Rya Muller, Kabelele Sipalo, Caitlyn Beals, Angela Chazura, Stephanie Chola, Roxanna Garcia, Brooks Jackson, Joseph Feinglass, Kirill V. Nourski, Marie-Renee Mala Wa Mpoyi, Humphrey Kunda and Rebecca Reynolds
J. Clin. Med. 2025, 14(16), 5721; https://doi.org/10.3390/jcm14165721 - 13 Aug 2025
Viewed by 942
Abstract
Background: Congenital anomalies impact 52 million infants worldwide with an estimated 94% living in low- and middle-income countries (LMICs). Approximately 200,000 children are born with a neural tube defect (NTD) in LMICs annually. Zambia is an LMIC with a high burden of [...] Read more.
Background: Congenital anomalies impact 52 million infants worldwide with an estimated 94% living in low- and middle-income countries (LMICs). Approximately 200,000 children are born with a neural tube defect (NTD) in LMICs annually. Zambia is an LMIC with a high burden of myelomeningocele (MMC; a severe form of NTD). This study sought to characterize the barriers influencing access to healthcare for children born with MMC in Zambia. Methods: Two cross-sectional surveys were administered to healthcare providers at referring public health facilities and mothers of infants born with MMC undergoing surgical closure. The survey among mothers was nested in a longitudinal study evaluating surgical closure in Lusaka, Zambia from 28 May 2024 to 21 January 2025. Results: Sixty-nine mother–MMC baby dyads and 123 providers from 21 facilities were enrolled in the study. The median age at presentation for MMC was 7.5 (range 0–244) days old. Most patients were referred from rural district hospitals (51%; n = 35) and travelled greater than 250 km to access care (80%; n = 55). Seventy-seven percent (n = 53) of mothers reported receiving at least one antenatal ultrasound, with 62% (n = 43) undergoing an ultrasound after 20 weeks estimated gestational age. Of these, only 3% (n = 2) received an MMC diagnosis prior to delivery. Referring patients with MMC for further care greater than six hours after birth was reported by 59% providers (n = 73). Hospitals further away from the tertiary center were more likely to report late referrals (p < 0.001). Conclusions: There is a delay in the diagnosis and referral of infants with MMC to specialized care in Zambia, which may be attributed to inadequate in utero diagnosis capabilities and distance from the tertiary facility. Improving the accuracy of prenatal diagnosis and strengthening referral pathways to facilitate access to care among infants with MMC in Zambia are important for improving incidence and outcomes. Full article
(This article belongs to the Special Issue Neurosurgery: Current Challenges and New Perspectives)
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16 pages, 4006 KB  
Article
Nesting and Foraging Preferences of Four Sympatric Species of Cavity-Nesting Leafcutting Bees (Hymenoptera: Megachilidae)
by Qianlei Dai, Junjie Hu, Xuan Liu, Jia Wan, Jiabao Wei, Dongshuo Yang and Chunling He
Insects 2025, 16(8), 831; https://doi.org/10.3390/insects16080831 - 11 Aug 2025
Viewed by 775
Abstract
Megachilidae are crucial pollinators of cultivated and wild vegetation, playing a vital role in ecosystem pollination services, however, there is still a lack of information regarding the ecology and behavior of these species. This study aims to analyze the nesting ecology strategies of [...] Read more.
Megachilidae are crucial pollinators of cultivated and wild vegetation, playing a vital role in ecosystem pollination services, however, there is still a lack of information regarding the ecology and behavior of these species. This study aims to analyze the nesting ecology strategies of four sympatric species of leafcutting bees and their interactions with pollen source plants. Data were collected from April to October from 2019 to 2022 in the Jiyuan section of the Taihang Mountain National Nature Reserve (approximately 35°10′–35°25′ N, 111°55′–112°10′ E) using trap nest methods. Through the dissection of nesting tubes, their structural characteristics were revealed, and the pollen sources collected by the bees were identified. Our results showed that nesting activity of leafcutting bees lasted from May to October, with a preference for nesting tubes of 6 to 10 mm in diameter and 131 to 170 mm in length. We documented 48 plant species used as foraging sources, belonging to 17 orders, 24 families, and 33 genera, with the Fagaceae family (9 species) being predominant. The results indicate that the distinctive traits of these species—such as the asynchronous nesting periods, the types of nesting materials, the dimensions of cavities, and differential utilization of floral resources—likely play a critical role in niche differentiation among sympatric species, thereby ensuring the maintenance and persistence of Megachilidae populations in this region. Full article
(This article belongs to the Section Social Insects and Apiculture)
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16 pages, 7321 KB  
Article
Ultra-Low Loss Hybrid Anti-Resonant Hollow-Core Fiber with Double Semi-Circular Tubes Sandwiched Elliptic Tube
by Zhipei Li, Shuaihang Wang, Ran Gao, Li Li, Lei Zhu, Qi Zhang and Xiangjun Xin
Photonics 2025, 12(6), 540; https://doi.org/10.3390/photonics12060540 - 26 May 2025
Viewed by 1520
Abstract
We propose a new hollow-core fiber design based on a hybrid structure of nested elliptical and semicircular tubes. We numerically investigate the loss and single-mode performance of this design in the communication band and derive the values of each parameter of the fiber [...] Read more.
We propose a new hollow-core fiber design based on a hybrid structure of nested elliptical and semicircular tubes. We numerically investigate the loss and single-mode performance of this design in the communication band and derive the values of each parameter of the fiber cladding structure that theoretically lead to the best performance of the fiber. The resulting structure has a minimum confinement loss as low as 0.00033 dB/km at 1550 nm and an astonishing extinction ratio of 2,439,607 for the higher-order modes, showing excellent loss and single-mode performance. In addition, the design also exhibits excellent bending insensitivity, with the loss gradually dropping well below 0.01 dB/km when the bending radius exceeds 14 cm. The proposed fiber structure has a very promising application in optical communication systems. Full article
(This article belongs to the Special Issue Advanced Optical Transmission Techniques)
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11 pages, 5339 KB  
Article
Simultaneous Achievement of Low Loss, Large Effective Mode Area and Wide Transmission Band Hollow-Core Anti-Resonant Optical Fibers
by Min Liu, Yingqi Cui, Xiangyu Hua, Wenjun Ni, Perry Ping Shum and Lei Huang
Sensors 2025, 25(10), 3003; https://doi.org/10.3390/s25103003 - 9 May 2025
Viewed by 907
Abstract
A novel nested structure of hollow-core anti-resonant optical fiber is proposed to achieve low loss, large effective mode area, and wide transmission band simultaneously in the near-infrared range of 1200–2200 nm. It is composed of six elliptical cladding tubes nested with six large [...] Read more.
A novel nested structure of hollow-core anti-resonant optical fiber is proposed to achieve low loss, large effective mode area, and wide transmission band simultaneously in the near-infrared range of 1200–2200 nm. It is composed of six elliptical cladding tubes nested with six large circular cladding tubes, and six small circular cladding tubes are introduced in the gap of the elliptical tubes. The transmission characteristics of the hollow-core anti-resonant optical fiber are numerically investigated using the full-vector finite element method. The effects of structural parameters such as the cladding tube thickness and the tube diameters on the fiber transmission characteristics are analyzed in detail. The results indicate that within the wavelength range of 1200–2200 nm, the confinement loss remains below 0.017 dB/km, and the minimum confinement loss can be as low as 1.2 × 10−4 dB/km at 1500 nm. The effective mode area remains as large as ~1142.5 μm2. It should be noted that in the wide wavelength range of 1000 nm, the dispersion exhibits excellent characteristics ranging from 0.7 to 1.4 ps/(nm·km). Our fiber can find potential applications in ultra-long-distance and ultra-high-power transmission systems with a wide operating wavelength band. Full article
(This article belongs to the Special Issue Specialty Optical Fiber-Based Sensors)
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13 pages, 1336 KB  
Article
First Report on the Molecular Detection and Characterization of Rickettsia felis in Laelapidae (Acari: Mesostigmata) Mites in Malaysia
by Hiryahafira Mohamad Tahir, Faraliana Che Lah Ernieenor, Suhaili Zainal Abidin, Vishalani Vishnu Narainasamy and Mariana Ahamad
Vet. Sci. 2025, 12(5), 443; https://doi.org/10.3390/vetsci12050443 - 6 May 2025
Viewed by 995
Abstract
Rickettsiae are Gram-negative and obligate intracellular bacteria that cause rickettsioses. These pathogens are typically transmitted by arthropod vectors, such as ticks, mesostigmatid mites, and fleas. Rickettsiae are responsible for many emerging infectious diseases worldwide and are the second most frequently reported cause of [...] Read more.
Rickettsiae are Gram-negative and obligate intracellular bacteria that cause rickettsioses. These pathogens are typically transmitted by arthropod vectors, such as ticks, mesostigmatid mites, and fleas. Rickettsiae are responsible for many emerging infectious diseases worldwide and are the second most frequently reported cause of non-malarial febrile illnesses in Southeast Asia. However, in Malaysia, studies on the prevalence and distribution of rickettsiae have primarily focused on humans, with limited data on these bacteria in vectors and small mammal hosts. Thus, this study aims to investigate the presence of Rickettsia spp. in small mammals and their associated mesostigmatid mites collected from potential rickettsioses areas in Selangor. Animal trapping was conducted across three different ecological study sites comprising a recreational area, agricultural land, and coastal area. A total of 41 small mammals and 363 mesostigmatid mites were collected and identified. Ten percent of the total individual mites were processed for morphological examination, and the remaining mites were then pooled by hosts, with five individual mites per tube, for DNA extraction. The collected samples, comprising blood, animal tissue, and pooled mites, were subjected to DNA extraction and were screened for Rickettsia spp. via nested polymerase chain reaction (PCR), targeting the citrate synthase-encoding gene (gltA) and outer membrane protein B gene (ompB). Interestingly, two pools (3.33%) of Laelaps spp. recovered from Maxomys whiteheadi and Bandicota indica, collected from a recreational area, tested positive for Rickettsia spp. Sequence analysis and phylogenetic tree of the ompB gene revealed the presence of Rickettsia felis in both laelapid mite pools. To our knowledge, this study provides the first molecular detection of R. felis in Laelaps spp. in Malaysia. Full article
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14 pages, 7896 KB  
Article
Ultra-Low-Loss Hollow-Core Anti-Resonant Fiber Combining Double-Tube Nesting and a Single-Layer Anti-Resonant Wall
by Xingtao Zhao, Mu Wang, Wenke Zhang, Jinlong Luo, Chang Liu, Sai Liu and Juncheng Li
Photonics 2025, 12(5), 440; https://doi.org/10.3390/photonics12050440 - 2 May 2025
Viewed by 1218
Abstract
This study innovatively presents a hollow-core anti-resonant fiber integrating double-tube nesting and a single-layer anti-resonant wall. Featuring an exclusive two-layer cladding configuration along with an outer cladding circular ring, it differs significantly from traditional fibers. After careful parameter optimization, at 1.55 μm wavelength, [...] Read more.
This study innovatively presents a hollow-core anti-resonant fiber integrating double-tube nesting and a single-layer anti-resonant wall. Featuring an exclusive two-layer cladding configuration along with an outer cladding circular ring, it differs significantly from traditional fibers. After careful parameter optimization, at 1.55 μm wavelength, the fiber shows excellent performance. Its confinement loss drops to 0.00088 dB/km, 1–2 orders lower than traditional ones. The proportion between the loss of the lowest higher-order mode and that of the fundamental mode reaches 19,900, indicating excellent single-mode performance. In the case of a bending radius of 11–14.2 cm, the x-polarization loss is below 0.001 dB/km, showing good bending resistance. Through structural comparisons, this paper quantitatively reveals the effects of the anti-resonant wall, cladding tube, and outer cladding ring on fiber performance. From the practical fiber-drawing process, it thoroughly analyzes the impact of the outer connecting tube’s offset angle on fiber performance. This research provides crucial theoretical support for new hollow-core fiber design, manufacture, and application, and is expected to drive technological innovation in this field. Full article
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15 pages, 21805 KB  
Article
Case Study on the Rupture Morphology of a Copper Tube in an Air Conditioner Condenser After Fire
by Yunlong Ou, Ming Fu, Jing Zhang, Wenzhong Mi, Changzheng Li, Shouhai Chen and Shoulei Zheng
Fire 2025, 8(4), 145; https://doi.org/10.3390/fire8040145 - 4 Apr 2025
Cited by 1 | Viewed by 1021
Abstract
The new eco-friendly flammable refrigerant in air conditioners has resulted in an annual increase in fire incidents associated with these units. Fire investigators face significant challenges in identifying the causes of these fires. In this study, copper tube samples were extracted from various [...] Read more.
The new eco-friendly flammable refrigerant in air conditioners has resulted in an annual increase in fire incidents associated with these units. Fire investigators face significant challenges in identifying the causes of these fires. In this study, copper tube samples were extracted from various locations of air conditioner condenser debris post fire. The morphology characteristics of the ruptured copper tubes formed by a high-temperature flame in fire and that formed by corrosion were analyzed, respectively. The findings indicate that the ruptures in the copper tubes of air conditioners may be classified into two types based on their origins: ruptures resulting from fire and ruptures resulting from corrosion. The ruptures in the copper tubes resulting from fire are associated with the presence of aluminum alloy fins. At elevated temperatures, the copper and aluminum atoms persist in diffusing and fracturing. A significant quantity of silver-white aluminum is present surrounding the ruptures, and distinct elemental layers may be seen in the cross-section. The corrosion-induced ruptures in the copper tubes are associated with ant nest corrosion. Despite the influence of high-temperature flame melting on surface corrosion pits, they will not entirely obscure the pits and the cross-section continues to exhibit the bifurcated structure characteristic of ant nest corrosion. This investigation demonstrates that corrosion of ant nests is the root cause of copper tube breakage obscured by flames. An investigation method for the refrigerant leakage air conditioning fire is proposed. The above findings can provide proof and method for air conditioning fire investigation. Full article
(This article belongs to the Special Issue Fire Detection and Public Safety, 2nd Edition)
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16 pages, 1742 KB  
Article
Modeling and Analysis of the Transverse Surface Roughness in Hollow-Core Fibers
by Federico Melli, Kostiantyn Vasko, Lorenzo Rosa, Fetah Benabid and Luca Vincetti
Fibers 2025, 13(4), 36; https://doi.org/10.3390/fib13040036 - 27 Mar 2025
Viewed by 825
Abstract
The corrugation of the interfaces of the cross-section of hollow core fibers based on the inhibited coupling waveguiding mechanism is modeled and the impact on propagation loss analyzed. The proposed model is based on a combined use of coupled-mode theory and Azimuthal Fourier [...] Read more.
The corrugation of the interfaces of the cross-section of hollow core fibers based on the inhibited coupling waveguiding mechanism is modeled and the impact on propagation loss analyzed. The proposed model is based on a combined use of coupled-mode theory and Azimuthal Fourier Decomposition. It shows that such transverse roughness causes coupling between the core modes and the dielectric modes of the cladding and consequently an increase of the fiber loss. The model is validated by comparing theoretical and numerical results obtained by applying both deterministic and stochastic corrugations to tubular lattice and nested fibers. Scaling laws and impact of the fibers’ parameters are discussed. The model shows that the loss increase is not directly correlated to the root mean square of the stochastic roughness but only to the value of the power spectral density in specific spatial frequency ranges. In particular, the spectral components characterized by a periodicity lower than 101 of the tube circumference must have a power spectral density value lower than 0.2 nm2 to ensure a negligible effect of the transverse roughness on fibers with losses lower than 0.1 dB/Km. Full article
(This article belongs to the Special Issue Characterization and Applications of Specialty Optical Fibers)
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29 pages, 2721 KB  
Review
Coaxial Pipes Used as Ground Buried Heat Exchangers—A Review of Research in Recent Years
by Geng Wang, Nai Rong, Xuefei Li, Ning Hu, Zhi Zhang, Yuan Zhang and Yuhan Wang
Buildings 2025, 15(2), 243; https://doi.org/10.3390/buildings15020243 - 15 Jan 2025
Viewed by 2058
Abstract
The efficient utilization of geothermal energy depends heavily on high-performance ground heat exchangers. Coaxial pipe is a high-efficiency heat exchanger composed of two nested tubes of different diameters. In this paper, the structure and thermal exchange characteristics of coaxial pipe geothermal exchangers are [...] Read more.
The efficient utilization of geothermal energy depends heavily on high-performance ground heat exchangers. Coaxial pipe is a high-efficiency heat exchanger composed of two nested tubes of different diameters. In this paper, the structure and thermal exchange characteristics of coaxial pipe geothermal exchangers are introduced, which are superior to single-U and double-U geothermal exchangers in respect of installation, heat transporting, and deep geothermal application. Thermal test research of coaxial pipe geothermal exchangers is investigated. Relevant studies in recent years on the factors affecting the thermal performance of coaxial pipe ground heat exchangers, including exchanger configurations, circulating fluids, subsurface conditions, flow patterns, and operational modes, are reviewed. In addition, research on the impact of coaxial pipe ground heat exchangers on the ground, as well as applications for coaxial pipe ground heat exchangers, is summarized. Recommendations are made for potential future research on coaxial pipe ground heat exchangers. It is believed that the results of these studies will help to raise awareness of coaxial pipe ground heat exchangers and to continue to promote their application. Full article
(This article belongs to the Special Issue Research on Indoor Air Environment and Energy Conservation)
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13 pages, 4299 KB  
Article
Design of a Nested Hollow-Core Anti-Resonant Fiber Sensor for Simultaneous Measurement of Temperature and Strain
by Yueyu Xiao and Jiayao Cheng
Sensors 2024, 24(23), 7805; https://doi.org/10.3390/s24237805 - 6 Dec 2024
Cited by 4 | Viewed by 1116
Abstract
A highly sensitive sensor, which can detect the temperature and strain simultaneously, is proposed using a hollow-core anti-resonant fiber with composite nested tubes. The sensing fiber contains two kinds of nested tubes, and two different sensing mechanisms, the resonance coupling effect and the [...] Read more.
A highly sensitive sensor, which can detect the temperature and strain simultaneously, is proposed using a hollow-core anti-resonant fiber with composite nested tubes. The sensing fiber contains two kinds of nested tubes, and two different sensing mechanisms, the resonance coupling effect and the intermodal interference, are realized in the same section of a hollow-core anti-resonant fiber fully filled with ethanol. Five conjoined nested anti-resonant tubes are introduced to suppress the confinement loss of the higher-order mode LP02. One hybrid conjoined nested tube, which consists of a half-circular anti-resonant tube and a half-circular resonant tube, is introduced to induce a resonant coupling between the LP02 mode in the core and the dielectric mode in the nested resonant tubes. Numerical investigations demonstrate the shifts of the feature wavelengths of the resonance coupling effect, and the intermodal interference shows different velocities with temperature and strain, while a simultaneous measurement of temperature and strain can be realized with high sensitivities (3.36 nm/°C and −0.003 nm/με to temperature and strain, respectively). Since the sensor can be fabricated by full infiltration with liquid into the large-size core and cladding tubes of hollow-core anti-resonant fibers, and special post-processing, such as selective infiltration or coating, is notneeded. The proposed sensors based on hollow-core anti-resonant fibers with functional liquid infiltration provide a more efficient and versatile platform for the temperature and strain sensing. Full article
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16 pages, 1531 KB  
Article
Expanded HPV Genotyping by Single-Tube Nested-Multiplex PCR May Explain HPV-Related Disease Recurrence
by Luiz Ricardo Goulart, Bruna França Matias Colombo, Mayara Ingrid Sousa Lima, Maria Socorro A. de Andrade, Juliana São Julião, Adriana Freitas Neves and Silma Regina Pereira
Microorganisms 2024, 12(11), 2326; https://doi.org/10.3390/microorganisms12112326 - 15 Nov 2024
Cited by 3 | Viewed by 2315
Abstract
The role of the human papillomavirus (HPV) in the establishment of cervical cancer has driven studies to find more effective methods of viral detection so that early intervention strategies can be performed. However, the methods still have limitations, especially regarding detecting the different [...] Read more.
The role of the human papillomavirus (HPV) in the establishment of cervical cancer has driven studies to find more effective methods of viral detection so that early intervention strategies can be performed. However, the methods still have limitations, especially regarding detecting the different genotypes simultaneously. We have developed a high-throughput system using a single-tube nested-multiplex polymerase chain reaction (NMPCR) for the detection of 40 HPV genotypes using capillary electrophoresis. The NMPCR assay was compared to the Hybrid Capture 2 assay (HC2) with 40 women from the Northeast of Brazil (São Luis, MA), a high endemic region, where the HPV positivity was 75% and 37.5%, respectively. These results were validated by performing a molecular epidemiological study on 5223 Brazilian women undergoing gynecological examinations from 2009 to 2017, who presented with an HPV prevalence of 59%. Multiple infections were found in 62.5% and 58% of the patients from the endemic region and from the Brazilian women population, respectively, mostly presenting high-risk genotypes (90.5% and 60%, respectively). Considering cervical intraepithelial neoplasia and adenocarcinomas, the sensitivity and specificity were 97.5% and 100%, respectively. The NMPCR assay was also capable of identifying viral subtypes in cases of multiple infections, even with low viral loads (10−6 ng/µL of HPV DNA). The NMPCR test is a promising and robust tool for HPV diagnostics and a screening tool for prevention of cervical cancer. Full article
(This article belongs to the Special Issue Detection and Identification of Pathogenic Bacteria and Viruses)
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23 pages, 84462 KB  
Article
Enhanced Crashworthiness Parameters of Nested Thin-Walled Carbon Fiber-Reinforced Polymer and Al Structures: Effect of Using Expanded Polypropylene Foam
by Muhammet Muaz Yalçın and Mehmet İskender Özsoy
Appl. Sci. 2024, 14(21), 9635; https://doi.org/10.3390/app14219635 - 22 Oct 2024
Cited by 3 | Viewed by 1212
Abstract
The in-plane loading conditions of carbon fiber/epoxy composite (CFRP) and aluminum nested-tube-reinforced expanded polypropylene (EPP) blocks were empirically examined. This study used crashworthiness metrics to estimate the best design configuration under quasi-static loading rates. The experimental phase began with lateral loading testing of [...] Read more.
The in-plane loading conditions of carbon fiber/epoxy composite (CFRP) and aluminum nested-tube-reinforced expanded polypropylene (EPP) blocks were empirically examined. This study used crashworthiness metrics to estimate the best design configuration under quasi-static loading rates. The experimental phase began with lateral loading testing of single and nested aluminum and CFRP specimen. In-plane crushing experiments were performed on EPP foam blocks reinforced with nested tubes. Both single and nested aluminum tubes had comparable force–response curves and maintained their load-bearing capacity throughout testing. Despite a load-carrying capacity drop above a particular displacement threshold, the CFRP specimens had superior specific energy absorption (SEA) values due to their lightweight nature. The triple-tube nested specimens with two smaller tubes exhibited the best SEA results (1.72 and 1.88 J/g, respectively, for the aluminum and CFRP nested samples). During concurrent tube deformation, the nested samples showed a synergistic connection that increased energy absorption, especially in the EPP foam blocks with reinforced tubes. The study also examined the effects of building nested specimens with aluminum exterior tubes and CFRP inner tubes, and vice versa. This method showed that CFRP tubes within aluminum outer tubes lowered specimen weight (from 93.1 g to 67.7 g) and energy absorption (from 160.2 J to 153.3 J). However, the weight reduction outweighed the energy absorption, increasing SEA values for certain composite material configurations (from 1.72 J/g to 2.26 J/g). Full article
(This article belongs to the Section Mechanical Engineering)
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