Search Results (25)

Photothermal therapy is a highly promising non-invasive treatment strategy, but its clinical application is still limited by issues such as insufficient light-to-heat conversion efficiency and potential biological toxicity. To address these challenges, this study employed a biomineralization strategy to synthesize gold nanoflowers (Van@Au₄ NFs) using vancomycin as a template. The synthesized Van@Au₄ NFs exhibited a uniform flower-like morphology with a hydrodynamic diameter of approximately 122 nm. Under 808 nm laser irradiation, this material demonstrated excellent photothermal properties, with a photothermal conversion efficiency of 34.94%, and remained stable after four cold-hot cycles. The introduction of vancomycin effectively enhanced the colloidal stability and photothermal conversion ability of the nanoflowers. In vitro experiments showed that Van@Au₄ NFs had an inhibition rate of 90.8% against Staphylococcus aureus and 95.18% against A549 tumor cells under near-infrared light irradiation. This study constructed an efficient photothermal agent, providing important experimental evidence for in vitro synergistic photothermal treatment of bacterial infections and tumors. Full article

Laser local forming is an effective method for reshaping optical glass, yet the deformation of the material during the cooling phase remains poorly understood. This study investigates the dynamic evolution of the molten pool, specifically focusing on the transition from an initial convex shape to a final “M-shaped” profile. A combined approach using thermal-fluid simulation and high-speed imaging experiments was employed to track the surface changes throughout the heating and cooling cycles. The results show that while the surface bulges outward during laser irradiation, the material redistributes after the laser is switched off due to non-uniform cooling and volumetric shrinkage. The specific roles of viscosity and surface tension in driving this reverse flow were identified. Furthermore, the study established a quantitative model linking laser parameters to the final surface dimensions, providing a reliable tool for predicting and controlling the precision of glass forming. Full article

The Pennes bioheat equation is the most widely used model for describing heat transfer in living tissue during thermal exposure. It is derived from the classical Fourier law of heat conduction and assumes energy exchange between blood vessels and surrounding tissues. The literature presents various numerical methods for solving the bioheat equation, with exact solutions developed for different boundary conditions and geometries. However, analytical models based on this framework are rarely reported. This study aims to develop an analytical three-dimensional model using MATHEMATICA software, with subsequent mathematical validation performed through COMSOL simulations, to characterize heat transfer in biological tissues induced by laser irradiation under various therapeutic conditions. The objective is to refine the conventional bioheat equation by introducing three key improvements: (a) incorporating a non-Fourier framework for the Pennes equation, thereby accounting for the relaxation time in thermal response; (b) integrating Dirac functions and the telegraph equation into the bioheat model to simulate localized point heating of diseased tissue; and (c) deriving a closed-form analytical solution for the Pennes equation in both its classical (Fourier-based) and improved (non-Fourier-based) formulations. This paper investigates the nuanced relationship between the relaxation time parameter in the telegraph equation and the thermal relaxation time employed in the bioheat transfer equation. Considering all these aspects, the optimal thermal relaxation time determined for these simulations was 1.16 s, while the investigated thermal exposure time ranged from 0.01 s to 120 s. This study introduces a generalized version of the model, providing a more realistic representation of heat exchange between biological tissue and blood flow by accounting for non-uniform temperature distribution. It is important to note that a reasonable agreement was observed between the two modeling approaches: analytical (MATHEMATICA) and numerical (COMSOL) simulations. As a result, this research paves the way for advancements in laser-based medical treatments and thermal therapies, ultimately contributing to more optimized therapeutic outcomes. Full article

This study introduces an innovative analytical solution to the time-fractional Cattaneo heat conduction equation, which models photothermal transport in metallic thin films subjected to short laser pulse irradiation. The model integrates the Caputo fractional derivative of order 0 < p ≤ 1, addressing non-Fourier heat conduction characterized by finite wave speed and memory effects. The equation is nondimensionalized through suitable scaling, incorporating essential elements such as a newly specified laser absorption coefficient and uniform initial and boundary conditions. A hybrid approach utilizing the finite Fourier cosine transform (FFCT) in spatial dimensions and the Laplace transform in temporal dimensions produces a closed-form solution, which is analytically inverted using the two-parameter Mittag–Leffler function. This function inherently emerges from fractional-order systems and generalizes traditional exponential relaxation, providing enhanced understanding of anomalous thermal dynamics. The resultant temperature distribution reflects the spatiotemporal progression of heat from a spatially Gaussian and temporally pulsed laser source. Parametric research indicates that elevating the fractional order and relaxation time amplifies temporal damping and diminishes thermal wave velocity. Dynamic profiles demonstrate the responsiveness of heat transfer to thermal and optical variables. The innovation resides in the meticulous analytical formulation utilizing a realistic laser source, the clear significance of the absorption parameter that enhances the temperature amplitude, the incorporation of the Mittag–Leffler function, and a comprehensive investigation of fractional photothermal effects in metallic nano-systems. This method offers a comprehensive framework for examining intricate thermal dynamics that exceed experimental capabilities, pertinent to ultrafast laser processing and nanoscale heat transfer. Full article

Laser wireless power transfer (LWPT) offers a transformative approach to wireless energy transmission, addressing critical limitations in unmanned aerial vehicles (UAVs) such as battery energy limitation. However, challenges like beam divergence, non-uniform irradiation, and alignment instability limit its practical application. Here, we present a lightweight air-floating metalens platform to overcome these barriers. This innovative lens focuses laser beams near the photovoltaic receiver with an energy distribution uniformity across a single spot at the focal plane that is 50 times greater than that of a conventional Gaussian beam spot, achieving a multi-spot energy distribution uniformity of up to 99% theoretically. Experimentally, we achieved 75% uniformity using a metalens sample. Simultaneously, our system maintains superior beam quality within a dynamic range of 4 m and enhances charging efficiency by 1.5 times. Our research provides a robust technical solution to improve UAV endurance, enabling efficient, long-range wireless power transfer and opening broader technological implications. Full article

The fabrication of stable, tailored domain patterns in ferroelectric crystals has wide applications in optical and electronic industries. All-optical ferroelectric poling by pulse laser irradiation has been developed recently. In this work, we studied the creation of the domain structures in MgO-doped lithium tantalate by focused irradiation with a femtosecond near-infrared laser. Cherenkov-type second harmonic generation microscopy was used for domain imaging of the bulk. We have revealed the creation of enveloped domains around the induced microtracks under the action of the depolarization field. The domain growth is due to a pyroelectric field caused by a nonuniform temperature change. The domains in the bulk were revealed to have a three-ray star-shaped cross-section. It was shown that an increase in the field excess above the threshold leads to consequential changes in domain shape from a three-ray star to a triangular and a circular shape. The appearance of comb-like domains as a result of linear scanning was demonstrated. All effects were considered in terms of a kinetic approach, taking into account the domain wall motion by step generation and kink motion driven by excess of the local field over the threshold. The obtained knowledge is useful for the all-optical methods of domain engineering in ferroelectrics. Full article

The ancient building complex in Wudang Mountain, China, is known as the “Museum of Ancient Chinese Architectural Accomplishments”. However, the valuable stone components are preserved in open or semi-open environments and environmental factors such as rain seriously threaten its sustainable conservation. In this context, a femtosecond laser processing method has been demonstrated to be able to prepare hierarchical micro-nano structures on the stone surface to regulate its wettability, achieving the purpose of sustainable conservation. In this paper, the processing mechanism and performance of the femtosecond laser on green schist, a local stone material in the Wudang Mountain, are systematically investigated. It is found that green schist, as a typical non-homogeneous material, exhibits significant differences in its absorption of femtosecond laser with different compositions. Among them, quartz, chlorite, and muscovite are the three main compositions, and they are mainly characterized by cold ablation, thermal melting, and expansion under the irradiation of the femtosecond laser (238 fs, 100 kHz, 40 μJ, 33 μm, 500–40,000 pulses), respectively, and it is difficult to achieve a uniform and stable surface structure. Based on this, we prepared grooves with a spacing of 100–400 μm by scanning the femtosecond laser. Through the characterization of surface morphology, elemental composition, and three-dimensional structure, the processing mechanism of the hierarchical micro-nano structures of green schist under the irradiation of the femtosecond laser is comprehensively revealed. Finally, the wettability modulation result of water contact angle up to 147° is achieved by processing the grooves with an optimal spacing of 400 μm. The results of this research are of guiding significance for the sustainable conservation of ancient buildings and cultural relics. Full article

In a long-distance wireless power transmission system with a non-uniform distribution of laser irradiation, it will significantly reduce the output power of the photovoltaic array, resulting in a large amount of power loss in the system and a decrease in conversion efficiency. This paper proposes an efficient and reliable optimal circuit connection algorithm for the 5 × 5 scale photovoltaic array. Under the laser illumination of 300 W, a 20 m wireless power transmission experiment was performed on four 5 × 5 scale photovoltaic arrays. The results show a 56.49% increase in the maximum output power of the 5 × 5 scale photovoltaic array. Full article

The systematic imaging of the damaged tracks and domain patterns created in the MgOLN plates by one-step fs-laser irradiation at different depths was carried out. It is shown that the domains in the bulk have a spindle-like shape and start to grow in the Z− direction from the track ends. The domain shape changes from a spindle-like one with charged walls to a hexagonal prism with neutral walls after the domain reaches the polar surface. The length of the domains located in the bulk increases linearly with the pulse energy. The hexagonal domain shape at the surface is typical for the crystals of the lithium niobate family. The obtained effects have been considered in terms of the kinetic approach. After irradiation, the domains appear in the vicinity of the track ends with maximum electric field strength and grow under the action of a spatially nonuniform pyroelectric field. The key role of the pyroelectric field is confirmed by the creation of new domains at the surface without correlation with the position of the focusing point located at the vicinity of the surface. The 3D domain pattern was produced, which represented four layers of the regular matrices consisting of elongated domains about 100 μm in length. Full article

Large-area nanostructuring of glasses using intense laser beams is a challenging task due to the material’s extreme non-linear absorption of laser energy. Precise optimization of the process parameters is essential for fabricating nanostructures with large-area coverage. In this study, we report the findings on creating high-spatial-frequency LIPSS (HSFL) on borosilicate glass through direct laser writing, using a femtosecond laser with a wavelength λ = 800 nm, pulse duration τ = 35 fs, and repetition frequency f_rep = 1 kHz. We measured the single-pulse ablation threshold and incubation factor of Borosilicate glasses to achieve high-precision control of the large-area surface structuring. Single-spot experiments indicated that, when there was higher fluence and a larger number of irradiated laser pulses, a melt formation inside the irradiated area limited the uniformity of LIPSS formation. Additionally, the orientation of the scan axis with the laser beam polarization was found to significantly influence the uniformity of LIPSS generated along the scan line, with more redeposition and melt formation when the scan axis was perpendicular to the laser beam polarization. For large-area processing, the borosilicate glass surface was scanned line-by-line by the laser beam, with a scan orientation parallel to the polarization of the laser. The optical characterization revealed that the transmittance and reflectance of the borosilicate glass decreased significantly after processing. Additionally, the surface’s wettability changed from hydrophilic to super-hydrophilic after processing. These chemical contamination-free and uniformly distributed structures have potential applications in optics, microfluidics, photovoltaics, and biomaterials. Full article

Novel biocompatible and efficient photothermal (PT) therapeutic materials for cancer treatment have recently garnered significant attention, owing to their effective ablation of cancer cells, minimal invasiveness, quick recovery, and minimal damage to healthy cells. In this study, we designed and developed calcium ion-doped magnesium ferrite nanoparticles (Ca²⁺-doped MgFe₂O₄ NPs) as novel and effective PT therapeutic materials for cancer treatment, owing to their good biocompatibility, biosafety, high near-infrared (NIR) absorption, easy localization, short treatment period, remote controllability, high efficiency, and high specificity. The studied Ca²⁺-doped MgFe₂O₄ NPs exhibited a uniform spherical morphology with particle sizes of 14.24 ± 1.32 nm and a strong PT conversion efficiency (30.12%), making them promising for cancer photothermal therapy (PTT). In vitro experiments showed that Ca²⁺-doped MgFe₂O₄ NPs had no significant cytotoxic effects on non-laser-irradiated MDA-MB-231 cells, confirming that Ca²⁺-doped MgFe₂O₄ NPs exhibited high biocompatibility. More interestingly, Ca²⁺-doped MgFe₂O₄ NPs exhibited superior cytotoxicity to laser-irradiated MDA-MB-231 cells, inducing significant cell death. Our study proposes novel, safe, high-efficiency, and biocompatible PT therapeutics for treating cancers, opening new vistas for the future development of cancer PTT. Full article

Femtosecond laser-modified amorphous silicon (a-Si) films with optical and electrical anisotropy have perspective polarization-sensitive applications in optics, photovoltaics, and sensors. We demonstrate the formation of one-dimensional femtosecond laser-induced periodic surface structures (LIPSS) on the surface of phosphorus- (n-a-Si) and boron-doped (p-a-Si) amorphous silicon films. The LIPSS are orthogonal to the laser polarization, and their period decreases from 1.1 ± 0.1 µm to 0.84 ± 0.07 µm for p-a-Si and from 1.06 ± 0.03 to 0.98 ± 0.01 for n-a-Si when the number of laser pulses per unit area increases from 30 to 120. Raman spectra analysis indicates nonuniform nanocrystallization of the irradiated films, with the nanocrystalline Si phase volume fraction decreasing with depth from ~80 to ~40% for p-a-Si and from ~20 to ~10% for n-a-Si. LIPSS’ depolarizing effect, excessive ablation of the film between LIPSS ridges, as well as anisotropic crystalline phase distribution within the film lead to the emergence of conductivity anisotropy of up to 1 order for irradiated films. Current–voltage characteristic nonlinearity observed for modified p-a-Si samples may be associated with the presence of both the crystalline and amorphous phases, resulting in the formation of potential barriers for the in-plane carrier transport and Schottky barriers at the electric contacts. Full article

A photovoltaic panels is a device used for converting solar and other energy into electrical energy. In laser wireless power transmission, there is a problem that the conversion efficiency of the photovoltaic panel is not as high as that of a single photovoltaic cell, and the output power is not as large as expected. This is not conducive to the popularization and use of wireless power transmission via laser. It is important to find out why the output power of the photovoltaic panel irradiated by lasers is not high. According to the laser intensity distribution equation, it is deduced that the laser in a very small area has an equivalent uniformity intensity distribution through the comparative calculation of the light intensity of two adjacent points. Then, the input non-uniform laser can be broken down into many equivalent uniform small lasers with different light intensity values. Based on this theory, the photovoltaic array model under laser was established, and it was simulated by MATLAB/Simulink. The simulation results reveal that the greater the difference between the light intensity values of these small spots, that is to say, the more non-uniform the laser, the lower the output power of the photovoltaic module illuminated by it. A multi-wavelength experimental platform was built, and comparative experiments of laser wireless power transmission were carried out using three kinds of lasers: 808, 532, and 1030 nm. The experimental result was in good agreement with the simulation result. The above results show that the deduced theory and the model based on it are correct. Full article

Laser wireless power transmission (LWPT) has various applications for mobile devices and specific equipment under extreme conditions. The light spot received by laser photovoltaics is usually non-uniform, resulting in system efficiency reduction. The output characteristics of 1 × 1 cm² GaAs laser photovoltaics were measured under various illuminated areas. The experimental results showed that the efficiency decreased from 40.8% at the full irradiated area to 26.7% at 1/10 irradiated area. Furthermore, the drop in short-circuit current was the main factor for decreasing the efficiency. A three-dimensional (3D) finite element model was used to investigate this factor. The simulation results indicated that non-uniform irradiation could increase the total non-radiative recombination rate. The recombination rate of the absorption region increased from 6.0 × 10²⁰ cm⁻³/s to 2.5 × 10²¹ cm⁻³/s, reducing the short-circuit current. Full article

Ultrafast, high-sensitivity deep-ultraviolet (UV) photodetectors are crucial for practical applications, including optical communication, ozone layer monitoring, flame detection, etc. However, fast-response UV photodetectors based on traditional materials suffer from issues of expensive production processes. Here, we focused on pyrite with simultaneously cheap production processes and ultrafast response speed. Nanoseconds photovoltaic response was observed under UV pulsed laser irradiation without an applied bias at room temperature. In addition, the response time of the laser-induced voltage (LIV) signals was ~20 ns, which was the same as the UV laser pulse width. The maximum value of the responsivity is 0.52 V/mJ and the minimum value of detectivity was about to ~1.4 × 10¹³ Jones. When there exists nonuniform illumination, a process of diffusion occurs by which the carriers migrate from the region of high concentration toward the region of low concentration. The response speed is limited by a factor of the diffusion of the carriers. With an increment in laser energy, the response speed of LIV is greatly improved. The high response speed combined with low-cost fabrication makes these UV photodetectors highly attractive for applications in ultrafast detection. Full article