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16 Results Found

  • Review
  • Open Access
5 Citations
4,370 Views
12 Pages

Parenchymal Sparing Resection: Options in Duodenal and Pancreatic Surgery

  • Ugo Marchese,
  • Stylianos Tzedakis,
  • Einas Abou Ali,
  • Olivier Turrini,
  • Jean-Robert Delpero,
  • Romain Coriat and
  • David Fuks

2 April 2021

Parenchymal sparing duodenal and pancreatic resection are safe procedures in selected patients with the aim to reduce endocrine and exocrine long-term dysfunction. When the tumor is benign or borderline malignant, this appears to be a good option for...

  • Article
  • Open Access
4 Citations
1,345 Views
12 Pages

14 October 2023

(1) Background: Patients with pancreatic Neuroendocrine Neoplasms (PanNENs) often have a long overall survival. We evaluated determinants of quality of life (QoL) after surgery for PanNENs. (2) Methods: Patients operated on for a PanNEN in our center...

  • Article
  • Open Access
14 Citations
4,217 Views
14 Pages

Long-Term Pancreatic Functional Impairment after Surgery for Neuroendocrine Neoplasms

  • Valentina Andreasi,
  • Stefano Partelli,
  • Gabriele Capurso,
  • Francesca Muffatti,
  • Gianpaolo Balzano,
  • Stefano Crippa and
  • Massimo Falconi

3 October 2019

Radical surgery represents the only curative treatment for pancreatic neuroendocrine neoplasms (PanNEN). The aim of this study was to evaluate the postoperative onset of diabetes mellitus (DM) and/or pancreatic exocrine insufficiency (PEI) in surgica...

  • Review
  • Open Access
23 Citations
5,102 Views
17 Pages

Surgical Management of Neuroendocrine Tumours of the Pancreas

  • Regis Souche,
  • Christian Hobeika,
  • Elisabeth Hain and
  • Sebastien Gaujoux

16 September 2020

Neuroendocrine tumours of the pancreas (pNET) are rare, accounting for 1–2% of all pancreatic neoplasms. They develop from pancreatic islet cells and cover a wide range of heterogeneous neoplasms. While most pNETs are sporadic, some are associa...

  • Review
  • Open Access
12 Citations
7,210 Views
16 Pages

Multimodal Management of Grade 1 and 2 Pancreatic Neuroendocrine Tumors

  • Ugo Marchese,
  • Martin Gaillard,
  • Anna Pellat,
  • Stylianos Tzedakis,
  • Einas Abou Ali,
  • Anthony Dohan,
  • Maxime Barat,
  • Philippe Soyer,
  • David Fuks and
  • Romain Coriat

15 January 2022

Pancreatic neuroendocrine tumors (p-NETs) are rare tumors with a recent growing incidence. In the 2017 WHO classification, p-NETs are classified into well-differentiated (i.e., p-NETs grade 1 to 3) and poorly differentiated neuroendocrine carcinomas...

  • Review
  • Open Access
2 Citations
1,733 Views
14 Pages

Complete surgical resection in the context of a multimodal approach has been associated with excellent long-term survival in children diagnosed with pancreatoblastoma (PB). Traditionally, curative intent surgery for PB implies standard pancreatic res...

  • Article
  • Open Access
8 Citations
1,981 Views
8 Pages

1 August 2014

Pancreatic cancer is the 4th leading cause of cancerrelated death. Complete surgical resection (CR0) is considered the only curative treatment. Most patients present with unresectable or borderline resectable disease. Many small phase i/ii trials hav...

  • Review
  • Open Access
47 Citations
6,062 Views
18 Pages

Diagnostic and Interventional Role of Endoscopic Ultrasonography for the Management of Pancreatic Neuroendocrine Neoplasms

  • Giuseppinella Melita,
  • Socrate Pallio,
  • Andrea Tortora,
  • Stefano Francesco Crinò,
  • Antonio Macrì and
  • Gianlorenzo Dionigi

15 June 2021

Pancreatic neuroendocrine neoplasms (PanNENs) are relatively rare, but their incidence has increased significantly in the last decades. Precise diagnosis and prognostic stratification are crucial for proper patient management. Endoscopic ultrasound (...

  • Review
  • Open Access
12 Citations
4,639 Views
20 Pages

27 November 2021

Pancreatic neuroendocrine tumours (pNETs) represent 1 to 2% of all pancreatic neoplasm with an increasing incidence. They have a varied clinical, biological and radiological presentation, depending on whether they are sporadic or genetic in origin, w...

  • Systematic Review
  • Open Access
5 Citations
3,412 Views
13 Pages

Pancreatic Neuroendocrine Tumors: What Is the Best Surgical Option?

  • Renato Patrone,
  • Federico Maria Mongardini,
  • Alessandra Conzo,
  • Chiara Cacciatore,
  • Giovanni Cozzolino,
  • Antonio Catauro,
  • Eduardo Lanza,
  • Francesco Izzo,
  • Andrea Belli and
  • Raffaele Palaia
  • + 4 authors

20 May 2024

Background: Pancreatic neuroendocrine tumors (pNETs) represent a rare subset of pancreatic cancer. Functional tumors cause hormonal changes and clinical syndromes, while non-functional ones are often diagnosed late. Surgical management needs multidis...

  • Article
  • Open Access
719 Views
18 Pages

10 September 2025

Background/Objectives: Traditional thermal ablation for pancreatic cancer is limited by collateral injury, often leading to complications such as pancreatitis. Irreversible electroporation (IRE) is a non-thermal alternative. We investigated tissue re...

  • Article
  • Open Access
1 Citations
1,917 Views
12 Pages

When Should Lymphadenectomy Be Performed in Non-Metastatic Pancreatic Neuroendocrine Tumors? A Population-Based Analysis of the German Clinical Cancer Registry Group

  • Thaer S. A. Abdalla,
  • Louisa Bolm,
  • Monika Klinkhammer-Schalke,
  • Sylke Ruth Zeissig,
  • Kees Kleihues van Tol,
  • Peter Bronsert,
  • Stanislav Litkevych,
  • Kim C. Honselmann,
  • Rüdiger Braun and
  • Judith Gebauer
  • + 4 authors

19 January 2024

Background: Patient selection for lymphadenectomy remains a controversial aspect in the treatment of pancreatic neuroendocrine tumors (pNETs), given the growing importance of parenchyma-sparing resections and minimally invasive procedures. Methods: T...

  • Article
  • Open Access
548 Views
15 Pages

Quality of Life After Pancreatic Surgery for Neuroendocrine Tumors of the Pancreas: Observational Study of Long-Term Outcomes

  • Anna Caterina Milanetto,
  • Claudia Armellin,
  • Daniele Gasparini,
  • Giulia Lorenzoni and
  • Claudio Pasquali

1 October 2025

Background/Objectives: Patients with pancreatic neuroendocrine tumors (PanNETs) often have a good prognosis with long overall survival. We evaluated quality of life (QoL) after surgery for PanNETs, using the new EORTC-specific questionnaires. Methods...

  • Article
  • Open Access
6 Citations
3,082 Views
10 Pages

Clinical Course, Genetic, and Immunohistochemical Characterization of Solid Pseudopapillary Tumor of the Pancreas (Frantz Tumors) in a Brazilian Cohort

  • Francinne T. Tostes,
  • Parisina Fraga Dutra Cabral de Carvalho,
  • Raphael L. C. Araújo,
  • Rodrigo Chaves Ribeiro,
  • Franz Robert Apodaca-Torrez,
  • Edson José Lobo,
  • Diogo Bugano Diniz Gomes,
  • Donato Callegaro-Filho,
  • Gustavo Schvartsman and
  • Fernando Moura
  • + 5 authors

6 October 2022

Frantz tumors or solid pseudopapillary pancreatic neoplasm (SPN) are rare exocrine neoplasms that carry a favorable prognosis; they represent up to 3% of all tumors located in the region of the pancreas and have specific age and gender predisposition...

  • Article
  • Open Access

Minimally Invasive Resection of Occult Insulinomas—Experience from an ENETS Centre of Excellence and Review of the Literature

  • Alina S. Ritter,
  • Feline Ockenga,
  • Kira C. Steinkraus,
  • Jelte Poppinga,
  • Philipp H. von Kroge,
  • Tania Amin,
  • Fabrice Viol,
  • Thorben W. Fründt,
  • Felix Nickel and
  • Thilo Hackert
  • + 1 author
Cancers2025, 17(23), 3857;https://doi.org/10.3390/cancers17233857 
(registering DOI)

30 November 2025

Background/Objectives: Insulinomas are rare insulin-secreting pancreatic neuroendocrine tumours (pNETs). Preoperative tumour localisation can usually be achieved by computed tomography (CT), magnetic resonance imaging, or positron emission tomography...

  • Article
  • Open Access
3 Citations
2,682 Views
11 Pages

Isolated Gastric Metastases of Pancreatic Ductal Adenocarcinoma following Radical Resection—Impact of Endosonography-Guided Fine Needle Aspiration Tract Seeding

  • Martin Loveček,
  • Pavel Skalický,
  • Ondřej Urban,
  • Jana Tesaříková,
  • Martin Kliment,
  • Róbert Psár,
  • Hana Švébišová,
  • Kateřina Urban,
  • Beatrice Mohelníková-Duchoňová and
  • Dušan Klos
  • + 1 author

Background: Endosonography-guided fine needle aspiration biopsy (EUS-FNA)-associated metachronous gastric seeding metastases (GSM) of pancreatic ductal adenocarcinoma (PDAC) represent a serious condition with insufficient evidence. Methods: Retrospec...