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23 pages, 1149 KB  
Article
Demand Segmentation for Sustainable Adventure Destination Management: A Study of Santa Elena, Ecuador
by Miguel Orden-Mejía, Mauricio Carvache-Franco, Paola Palomino-Flores, Orly Carvache-Franco, Mónica Torres-Naranjo, Wilmer Carvache-Franco and María Alejandro-Lindao
Sustainability 2025, 17(20), 9039; https://doi.org/10.3390/su17209039 (registering DOI) - 13 Oct 2025
Abstract
Adventure tourism has established itself as a growing sector that integrates physical activity, interaction with nature, and cultural exchange. Understanding the heterogeneity of demand is crucial for designing effective and sustainable destination management strategies. Despite the global growth of adventure tourism, there is [...] Read more.
Adventure tourism has established itself as a growing sector that integrates physical activity, interaction with nature, and cultural exchange. Understanding the heterogeneity of demand is crucial for designing effective and sustainable destination management strategies. Despite the global growth of adventure tourism, there is a scarcity of empirical studies analyzing the motivations, segmentation, and loyalty of tourists in emerging coastal destinations. This study contributes to filling this gap by providing evidence from the case of Santa Elena, Ecuador. This study examines the motivations, market segmentation, and loyalty of adventure tourists in Santa Elena, an emerging coastal destination in Ecuador. Based on a survey of 318 visitors and using exploratory factor analysis (EFA) and k-means cluster segmentation, five motivational dimensions were identified: learning, social, biosecurity, relaxation, and competence-mastery. The results revealed two distinct segments: (i) Relaxation seekers, primarily motivated by rest and stress reduction, and (ii) multi-motivation tourists, with high levels of motivation across all dimensions. This latter group showed greater loyalty, evidenced by the intention to return, recommend, and spread a positive image of the destination. The study contributes to academic knowledge by proposing a motivation-based segmentation model that integrates emerging dimensions such as biosecurity and offers practical implications for the sustainable management of adventure destinations. It recommends designing differentiated tourism products that cater to dominant motivations, thereby strengthening competitiveness and contributing to the sustainability of tourism in emerging contexts. Full article
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13 pages, 814 KB  
Article
The Influence of Rehabilitation Programs on the Mental State and Quality of Life in Patients with Fibromyalgia: A Comparative Cohort Study from Romania
by Theodora Florica Borze (Ursu), Annamaria Pallag, Doriana Ioana Ciobanu, Klara Kalman, Anca Paula Ciurba, Ramona Nicoleta Suciu, Mariana Mureșan and Carmen Delia Nistor-Cseppento
Int. J. Environ. Res. Public Health 2025, 22(10), 1553; https://doi.org/10.3390/ijerph22101553 (registering DOI) - 12 Oct 2025
Abstract
Fibromyalgia (FM) affects millions of people around the world, causing widespread physical pain, exhaustion, and psychological disorders. Through this study, we aim to observe the effectiveness of two different rehabilitation programs in reducing the impact of FM on daily functioning and psychological factors. [...] Read more.
Fibromyalgia (FM) affects millions of people around the world, causing widespread physical pain, exhaustion, and psychological disorders. Through this study, we aim to observe the effectiveness of two different rehabilitation programs in reducing the impact of FM on daily functioning and psychological factors. Specifically, we compare a complex conservative program that combines physical therapy and hydrokinetotherapy in a hospital setting with a therapy focused on intrinsic relaxation. Methods: This comparative study involved 63 patients aged between 19 and 69 years diagnosed with FM, divided into two groups: the study group (SG, 32 participants) and the control group (CG, 31 participants). Over 90% of participants are female, 30 in the study group and 28 in the control group. SG followed a conservative physiotherapy combined with thermal water therapy, and CG followed a recovery program through intrinsic relaxation. Participants were evaluated on the first and last day of the rehabilitation program using the Revised Fibromyalgia Impact Questionnaire (FIQR) and the Hamilton Anxiety Rating Scale (Ham—A). The rehabilitation program consisted of 10 sessions conducted over a period of two weeks. Results: After the two-week recovery period, the results showed a significant improvement in both FIQR and Ham—A scores in the study group (p < 0.001). In the control group, there were no significant changes in FIQR variables (p > 0.05), while a significant improvement was observed on the anxiety scale (p < 0.001). Conclusions: The combination of hydrokineto-therapy and physical therapy is more effective in improving the overall condition of patients with FM compared to relaxation. Full article
(This article belongs to the Special Issue The Impact of Physical Activity on Mental Health and Well-Being)
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12 pages, 1430 KB  
Article
Influence of LPCVD-Si3N4 Thickness on Polarization Coulomb Field Scattering in AlGaN/GaN Metal–Insulator–Semiconductor High-Electron-Mobility Transistors
by Guangyuan Jiang, Weikang Li, Xin Luo, Yang Liu, Chen Fu, Qingying Zhang, Guangyuan Zhang, Zhaojun Lin and Peng Cui
Micromachines 2025, 16(10), 1147; https://doi.org/10.3390/mi16101147 - 10 Oct 2025
Viewed by 33
Abstract
The thickness of the LPCVD-Si3N4 gate dielectric layer significantly influences the electron transport properties of AlGaN/GaN metal–insulator–semiconductor high-electron-mobility transistors (MIS-HEMTs), but the mechanism by which it affects polarization Coulomb field (PCF) scattering remains largely unexplored. In this study, AlGaN/GaN MIS-HEMTs [...] Read more.
The thickness of the LPCVD-Si3N4 gate dielectric layer significantly influences the electron transport properties of AlGaN/GaN metal–insulator–semiconductor high-electron-mobility transistors (MIS-HEMTs), but the mechanism by which it affects polarization Coulomb field (PCF) scattering remains largely unexplored. In this study, AlGaN/GaN MIS-HEMTs with LPCVD-Si3N4 gate dielectric thicknesses of 0 nm, 5 nm, and 20 nm were fabricated, and the influence of LPCVD-Si3N4 thickness on PCF scattering was systematically investigated. Through electrical measurements and theoretical calculations, the relationship between LPCVD-Si3N4 gate dielectric layer thickness, additional polarization charge (∆ρ), two-dimensional electron gas (2DEG) density, and 2DEG mobility was analyzed. The results show that increasing the LPCVD-Si3N4 thickness reduces the vertical electric field in the AlGaN barrier, weakening the inverse piezoelectric effect (IPE) and reducing ∆ρ. Further analysis reveals that the ∆ρ exhibits a non-monotonic dependence on negative gate voltage, initially increasing and subsequently decreasing, due to the competition between strain accumulation and stress relaxation. Meanwhile, the 2DEG mobility limited by PCF (μPCF) decreases monotonically with increasing negative gate voltage, mainly due to the progressive weakening of the 2DEG screening effect. The research results reveal the physical mechanism by which LPCVD-Si3N4 thickness regulates PCF scattering, providing theoretical guidance for optimizing gate dielectric parameters and enhancing the performance of AlGaN/GaN MIS-HEMTs. Full article
(This article belongs to the Section D1: Semiconductor Devices)
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24 pages, 774 KB  
Article
Electrical Analogy Approach to Fractional Heat Conduction Models
by Slobodanka Galovic, Marica N. Popovic and Dalibor Chevizovich
Fractal Fract. 2025, 9(10), 653; https://doi.org/10.3390/fractalfract9100653 - 9 Oct 2025
Viewed by 101
Abstract
Fractional heat conduction models extend classical formulations by incorporating fractional differential operators that capture multiscale relaxation effects. In this work, we introduce an electrical analogy that represents the action of these operators via generalized longitudinal impedance and admittance elements, thereby clarifying their physical [...] Read more.
Fractional heat conduction models extend classical formulations by incorporating fractional differential operators that capture multiscale relaxation effects. In this work, we introduce an electrical analogy that represents the action of these operators via generalized longitudinal impedance and admittance elements, thereby clarifying their physical role in energy transfer: fractional derivatives account for the redistribution of heat accumulation and dissipation within micro-scale heterogeneous structures. This analogy unifies different classes of fractional models—diffusive, wave-like, and mixed—as well as distinct fractional operator types, including the Caputo and Atangana–Baleanu forms. It also provides a general computational methodology for solving heat conduction problems through the concept of thermal impedance, defined as the ratio of surface temperature variations (relative to ambient equilibrium) to the applied heat flux. The approach is illustrated for a semi-infinite sample, where different models and operators are shown to generate characteristic spectral patterns in thermal impedance. By linking these spectral signatures of microstructural relaxation to experimentally measurable quantities, the framework not only establishes a unified theoretical foundation but also offers a practical computational tool for identifying relaxation mechanisms through impedance analysis in microscale thermal transport. Full article
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32 pages, 1492 KB  
Review
Quantitative MRI in Neuroimaging: A Review of Techniques, Biomarkers, and Emerging Clinical Applications
by Gaspare Saltarelli, Giovanni Di Cerbo, Antonio Innocenzi, Claudia De Felici, Alessandra Splendiani and Ernesto Di Cesare
Brain Sci. 2025, 15(10), 1088; https://doi.org/10.3390/brainsci15101088 - 8 Oct 2025
Viewed by 422
Abstract
Quantitative magnetic resonance imaging (qMRI) denotes MRI methods that estimate physical tissue parameters in units, rather than relative signal. Typical readouts include T1/T2 relaxation (ms; or R1/R2 in s−1), proton density (%), diffusion metrics (e.g., ADC in mm2/s, FA), [...] Read more.
Quantitative magnetic resonance imaging (qMRI) denotes MRI methods that estimate physical tissue parameters in units, rather than relative signal. Typical readouts include T1/T2 relaxation (ms; or R1/R2 in s−1), proton density (%), diffusion metrics (e.g., ADC in mm2/s, FA), magnetic susceptibility (χ, ppm), perfusion (e.g., CBF in mL/100 g/min; rCBV; Ktrans), and regional brain volumes (cm3; cortical thickness). This review synthesizes brain qMRI across T1/T2 relaxometry, myelin/MT (MWF, MTR/MTsat/qMT), diffusion (DWI/DTI/DKI/IVIM), susceptibility imaging (SWI/QSM), perfusion (DSC/DCE/ASL), and volumetry using a unified framework: physics and signal model, acquisition and key parameters, outputs and units, validation/repeatability, clinical applications, limitations, and future directions. Our scope is the adult brain in neurodegenerative, neuro-inflammatory, neuro-oncologic, and cerebrovascular disease. Representative utilities include tracking demyelination and repair (T1, MWF/MTsat), grading and therapy monitoring in gliomas (rCBV, Ktrans), penumbra and tissue-at-risk assessment (DWI/DKI/ASL), iron-related pathology (QSM), and early dementia diagnosis with normative volumetry. Persistent barriers to routine adoption are protocol standardization, vendor-neutral post-processing/QA, phantom-based and multicenter repeatability, and clinically validated cut-offs. We highlight consensus efforts and AI-assisted pipelines, and outline opportunities for multiparametric integration of complementary qMRI biomarkers. As methodological convergence and clinical validation mature, qMRI is poised to complement conventional MRI as a cornerstone of precision neuroimaging. Full article
(This article belongs to the Special Issue Application of MRI in Brain Diseases)
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15 pages, 1007 KB  
Article
Optimization of Convex Transmissive Volume Bragg Grating for Hyperspectral Imaging Applications
by Yueying Li, Jiazhu Duan, Xiangjie Zhao, Yingnan Peng, Yongquan Luo, Dayong Zhang and Yibo Chen
Optics 2025, 6(4), 49; https://doi.org/10.3390/opt6040049 - 7 Oct 2025
Viewed by 150
Abstract
The Volume Bragg Grating (VBG) imaging technique provides a novel approach to gaze-type hyperspectral imaging. However, collimation constraints of the incident beam during narrow-band filtering and high-spatial-resolution imaging introduce system complexity, hindering miniaturization and modularization of the optical system. To address these limitations, [...] Read more.
The Volume Bragg Grating (VBG) imaging technique provides a novel approach to gaze-type hyperspectral imaging. However, collimation constraints of the incident beam during narrow-band filtering and high-spatial-resolution imaging introduce system complexity, hindering miniaturization and modularization of the optical system. To address these limitations, this paper proposes a convex transmissive VBG structure with tunable design parameters to enhance the field of view (FOV), relax collimation requirements, improve imaging quality, narrow filter spectral bandwidth, and simplify the optical system design. For the precise analysis and optimization of convex VBG performance, we established a physical model for filtered imaging using a convex transmissive VBG with polychromatic extended sources. An evaluation metric termed the “Maximal Splitting Angle (MSA)” was introduced to quantify the dispersion extent of image spots. This approach was employed to investigate the intrinsic correlations between structural parameters (such as the radius of curvature, vector tilt angle, grating period, and thickness) and key system performance indicators (spatial resolution and spectral resolution). The necessity of optimizing these parameters was rigorously demonstrated. Theoretical analysis confirms that convex transmissive VBG achieves superior spatial and spectral resolution over planar VBG under reduced collimation constraints. The experimental results show a 58.5% enhancement in spatial resolution and a 63.6% improvement in spectral bandwidth for the convex transmissive VBG system. Crucially, while planar transmissive VBG suffers from stray fringe interference during wavelength tuning, its convex counterpart remains unaffected. This study proposes a novel device structure, offering new perspectives for optimizing VBG-filtered spectral imaging systems. Full article
(This article belongs to the Topic Color Image Processing: Models and Methods (CIP: MM))
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31 pages, 5792 KB  
Article
Development, Characterization, and Biological Evaluation of a Self-Healing Hydrogel Patch Loaded with Ciprofloxacin for Wound Dressings
by Wasan Al-Farhan, Osama H. Abusara, Mohammad Abu-Sini, Suhair Hikmat, Ola Tarawneh, Sameer Al-Kouz and Rania Hamed
Polymers 2025, 17(19), 2686; https://doi.org/10.3390/polym17192686 - 4 Oct 2025
Viewed by 507
Abstract
Hydrogels are crosslinked polymer chains that form a three-dimensional network, widely used for wound dressing due to their ability to absorb significant amounts of fluid. This study aimed to develop a hydrogel patch for wound dressing with self-healing properties, particularly for joints and [...] Read more.
Hydrogels are crosslinked polymer chains that form a three-dimensional network, widely used for wound dressing due to their ability to absorb significant amounts of fluid. This study aimed to develop a hydrogel patch for wound dressing with self-healing properties, particularly for joints and stretchable body parts, providing a physical barrier while maintaining an optimal environment for wound healing. Polyvinyl alcohol (PVA) and sodium carboxymethyl cellulose (Na CMC) were crosslinked with borax, which reacts with the active hydroxyl groups in both polymers to form a hydrogel. The patches were loaded with ciprofloxacin HCl (CIP), a broad-spectrum antibiotic used to prevent and treat various types of wound infections. Hydrogels were subjected to rheological, morphological, antimicrobial, self-healing, ex vivo release, swelling, cytotoxicity, wound healing, and stability studies. The hydrogels exhibited shear-thinning, thixotropic, and viscoelastic properties. Microscopic images of the CIP hydrogel patch showed a porous, crosslinked matrix. The antimicrobial activity of the patch revealed antibacterial effectiveness against five types of Gram-positive and Gram-negative bacteria, demonstrating a minimum inhibitory concentration of 0.05 μg/mL against E. coli. The swelling percentage was found to be 337.4 ± 12.7%. The cumulative CIP release percentage reached 103.7 ± 3.7% after 3 h, followed by zero-order release kinetics. The stability studies revealed that the crossover point shifted toward higher frequencies after 3 months of storage at room temperature, suggesting a relaxation in the hydrogel bonds. The cytotoxicity study revealed that the CIP hydrogel patch is non-cytotoxic. Additionally, the in vivo study demonstrated that the CIP hydrogel patch possesses wound-healing ability. Therefore, the CIP PVA/Na CMC/Borax patch could be used in wound dressing. Full article
(This article belongs to the Special Issue Biopolymers for Wound Management: Translation for Clinical Practice)
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86 pages, 1368 KB  
Article
Nonlinear Quasi-Classical Model of Isothermal Relaxation Polarization Currents in Functional Elements of Microelectronics, Optoelectronics, and Fiber Optics Based on Crystals with Ionic-Molecular Chemical Bonds with Complex Crystalline Structure
by Valeriy Kalytka, Ali Mekhtiyev, Yelena Neshina, Aleksey Yurchenko, Aliya Аlkina, Felix Bulatbayev, Valeriy Issayev, Kanat Makhanov, Dmitriy Lukin, Damir Kayumov and Alexandr Zaplakhov
Crystals 2025, 15(10), 863; https://doi.org/10.3390/cryst15100863 - 30 Sep 2025
Viewed by 183
Abstract
In this article, the mechanism of relaxation polarization currents occurring at a constant temperature (isothermal process) in crystals with ionic-molecular chemical bonds (CIMBs) in an alternating electric field was investigated. Methods of the quasi-classical kinetic theory of dielectric relaxation, based on solutions of [...] Read more.
In this article, the mechanism of relaxation polarization currents occurring at a constant temperature (isothermal process) in crystals with ionic-molecular chemical bonds (CIMBs) in an alternating electric field was investigated. Methods of the quasi-classical kinetic theory of dielectric relaxation, based on solutions of the nonlinear system of Fokker–Planck and Poisson equations (for the blocking electrode model) and perturbation theory (by expanding into an infinite series in powers of a dimensionless small parameter) were used. Generalized nonlinear mathematical expressions for calculating the complex amplitudes of relaxation modes of the volume-charge distribution of the main charge carriers (ions, protons, water molecules, etc.) were obtained. On this basis, formulas for the current density of relaxation polarization (for transient processes in a dielectric) in the k-th approximation of perturbation theory were constructed. The isothermal polarization currents are investigated in detail in the first four approximations (k = 1, 2, 3, 4) of perturbation theory. These expressions will be applied in the future to compare the results of theory and experiment, in analytical studies of the kinetics of isothermal ion-relaxation (in crystals with hydrogen bonds (HBC), proton-relaxation) polarization and in calculating the parameters of relaxers (molecular characteristics of charge carriers and crystal lattice parameters) in a wide range of field parameters (0.1–1000 MV/m) and temperatures (1–1550 K). Asymptotic (far from transient processes) recurrent formulas are constructed for complex amplitudes of relaxation modes and for the polarization current density in an arbitrary approximation k of perturbation theory with a multiplicity r by the polarizing field (a multiple of the fundamental frequency of the field). The high degree of reliability of the theoretical results obtained is justified by the complete agreement of the equations of the mathematical model for transient and stationary processes in the system with a harmonic external disturbance. This work is of a theoretical nature and is focused on the construction and analysis of nonlinear properties of a physical and mathematical model of isothermal ion-relaxation polarization in CIMB crystals under various parameters of electrical and temperature effects. The theoretical foundations for research (construction of equations and working formulas, algorithms, and computer programs for numerical calculations) of nonlinear kinetic phenomena during thermally stimulated relaxation polarization have been laid. This allows, with a higher degree of resolution of measuring instruments, to reveal the physical mechanisms of dielectric relaxation and conductivity and to calculate the parameters of a wide class of relaxators in dielectrics in a wide experimental temperature range (25–550 K). Full article
(This article belongs to the Section Inorganic Crystalline Materials)
13 pages, 3426 KB  
Article
Loss Separation Modeling and Optimization of Permalloy Sheets for Low-Noise Magnetic Shielding Devices
by Yuzheng Ma, Minxia Shi, Yachao Zhang, Teng Li, Yusen Li, Leran Zhang and Shuai Yuan
Materials 2025, 18(19), 4527; https://doi.org/10.3390/ma18194527 - 29 Sep 2025
Viewed by 298
Abstract
With the breakthroughs in quantum theory and the rapid advancement of quantum precision measurement sensor technologies, atomic magnetometers based on the spin-exchange relaxation-free (SERF) mechanism have played an increasingly important role in ultra-weak biomagnetic field detection, inertial navigation, and fundamental physics research. To [...] Read more.
With the breakthroughs in quantum theory and the rapid advancement of quantum precision measurement sensor technologies, atomic magnetometers based on the spin-exchange relaxation-free (SERF) mechanism have played an increasingly important role in ultra-weak biomagnetic field detection, inertial navigation, and fundamental physics research. To achieve high-precision measurements, SERF magnetometers must operate in an extremely weak magnetic field environment, while the detection of ultra-weak magnetic signals relies on a low-noise background. Therefore, accurate measurement, modeling, and analysis of magnetic noise in shielding materials are of critical importance. In this study, the magnetic noise of permalloy sheets was modeled, separated, and analyzed based on their measured magnetic properties, providing essential theoretical and experimental support for magnetic noise evaluation in shielding devices. First, a single-sheet tester (SST) was modeled via finite element analysis to investigate magnetization uniformity, and its structure was optimized by adding a supporting connection plate. Second, an experimental platform was established to verify magnetization uniformity and to perform accurate low-frequency measurements of hysteresis loops under different frequencies and field amplitudes while ensuring measurement precision. Finally, the Bertotti loss separation method combined with a PSO optimization algorithm was employed to accurately fit and analyze the three types of losses, thereby enabling precise separation and calculation of hysteresis loss. This provides essential theoretical foundations and primary data for magnetic noise evaluation in shielding devices. Full article
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20 pages, 2190 KB  
Article
Anatomy-Based Assessment of Spinal Posture Using IMU Sensors and Machine Learning
by Rabia Koca and Yavuz Bahadır Koca
Sensors 2025, 25(19), 5963; https://doi.org/10.3390/s25195963 - 25 Sep 2025
Viewed by 696
Abstract
Background: This study used inertial measurement unit (IMU)-based posture angle estimates to define proxy risk labels and investigated whether these labels can be predicted from demographic, anthropometric, and lifestyle variables through machine learning analysis. Methods: Thirty healthy individuals aged 18–25 years were included. [...] Read more.
Background: This study used inertial measurement unit (IMU)-based posture angle estimates to define proxy risk labels and investigated whether these labels can be predicted from demographic, anthropometric, and lifestyle variables through machine learning analysis. Methods: Thirty healthy individuals aged 18–25 years were included. Demographic and anthropometric data and information on daily living activities were collected. The IMU sensors were placed at vertebral levels C1, C7, T5, T12, and L5. Participants were instructed to stand in an upright posture, followed by a relaxed daily posture. Anatomic postural changes between these positions were analyzed. Cervical lordosis, thoracic kyphosis, lumbar lordosis, and scoliosis risks were predicted using machine learning algorithms, including Random Forest (RF) and Artificial Neural Networks (ANN). Results: Incorrect postures during desk work and phone use were associated with an increased likelihood of posture-related deviations, such as cervical lordosis, thoracic kyphosis, and lumbar lordosis. Conversely, daily physical activity reduced these deviations. Using LOSO and stratified cross-validation with imbalance handling, balanced accuracies ranged between 0.55 and 0.82 across targets, with majority-class baselines between 0.53 and 0.87. For cervical lordosis risk, RF achieved a 0.82 balanced accuracy (95% CI: 0.74–0.97), while other categories showed a moderate but consistent performance. AUPRC values exceeded baseline levels across all models. Conclusions: IMU-based posture angle estimates can be used to identify posture-related risk categories. In this study, ML models have demonstrated predictive relationships with demographic, anthropometric, and lifestyle variables. These findings provide exploratory evidence based on IMU-derived proxy labels in a small cohort of healthy young adults. They represent exploratory indicators of postural deviation rather than clinical outcomes and may motivate future studies on preventive strategies. Importantly, the results remain underpowered relative to the a priori power targets and should be interpreted qualitatively. Full article
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22 pages, 5813 KB  
Article
A Method for Optimizing the Precision of a Five-Axis Machine Tool Based on Tolerance
by Hongxia Yan and Jinwei Fan
Machines 2025, 13(9), 870; https://doi.org/10.3390/machines13090870 - 18 Sep 2025
Viewed by 454
Abstract
The tolerance of critical components in five-axis machine tools directly impacts the overall machining accuracy of the entire system. This paper presents a tolerance optimization method for machine tools that is grounded in sensitivity theory and the NSGA-II algorithm. First, a mapping model [...] Read more.
The tolerance of critical components in five-axis machine tools directly impacts the overall machining accuracy of the entire system. This paper presents a tolerance optimization method for machine tools that is grounded in sensitivity theory and the NSGA-II algorithm. First, a mapping model is established to relate tolerance parameters to geometric and spatial motion errors. Second, a gradient-based sensitivity index, which has a clear physical interpretation and high computational efficiency, is defined to quantify the influence of individual tolerances on the spatial motion errors. Recognizing the limitations of existing tolerance allocation methods, this study introduces the innovative concept of tolerance control cost (the sum of the products of tolerance sensitivity and tolerance value for each parameter), and an optimization model is formulated to minimize this while ensuring the spatial motion error meets the requirement. The NSGA-II algorithm is employed to solve this model. Simulation results demonstrate that the tolerances of components can be significantly relaxed (thereby indirectly reducing manufacturing costs) while still ensuring the desired spatial motion error of the entire machine, validating the feasibility and effectiveness of the proposed method. Full article
(This article belongs to the Section Advanced Manufacturing)
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25 pages, 832 KB  
Review
The Role of Essential Oils in Sports Recovery and Performance
by Stanislava Ivanova, Zoya Dzhakova, Yana Gvozdeva, Gergana Petkova, Albena Ivanova and Elizabet Dzhambazova
Molecules 2025, 30(18), 3771; https://doi.org/10.3390/molecules30183771 - 17 Sep 2025
Viewed by 1136
Abstract
Recent clinical studies and scientific literature increasingly support the use of essential oils (EOs) as adjuncts in enhancing sports performance and recovery. They have demonstrated potential in modulating mood, alleviating fatigue, facilitating muscle recovery, and contributing to the overall physiological and psychological well-being [...] Read more.
Recent clinical studies and scientific literature increasingly support the use of essential oils (EOs) as adjuncts in enhancing sports performance and recovery. They have demonstrated potential in modulating mood, alleviating fatigue, facilitating muscle recovery, and contributing to the overall physiological and psychological well-being of athletes. Specifically, EOs such as peppermint and eucalyptus exhibit analgesic and anti-inflammatory properties, making them beneficial for managing exercise-induced muscle soreness and discomfort. Conversely, oils like lavender are recognized for their anxiolytic and sedative effects, which may improve sleep quality and promote relaxation. But both are essential for effective post-exercise recovery. As such, their strategic application may represent a valuable, complementary approach within the broader context of sports medicine and athletic training. Although EOs have been used for centuries in traditional medicine of various cultures to support physical performance, scientific research in the field of sports medicine remains still limited. Preliminary findings suggest promising effects on fatigue reduction, sleep, sympathetic activity, and endurance improvement. However, results are inconsistent, with some studies even showing no significant differences compared to placebo. Further rigorous research is needed to establish the efficacy and mechanisms of EOs in athletic settings. Full article
(This article belongs to the Special Issue Phytochemistry, Human Health and Molecular Mechanisms)
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14 pages, 2551 KB  
Article
Tissue-like Fracture Toughness and Stress–Relaxation Ability in PVA-Agar-Based Hydrogels for Biomedical Applications
by Ismael Lamas, Bhuvana L. Chandrashekar, Claudia C. Biguetti and Mohammad R. Islam
Gels 2025, 11(9), 747; https://doi.org/10.3390/gels11090747 - 17 Sep 2025
Viewed by 485
Abstract
Soft tissues exhibit remarkable stretchability, fracture toughness, and stress–relaxation ability. They possess a large water content to support cellular processes. Mimicking such a combination of mechanical and physical properties in hydrogels is important for tissue engineering applications but remains challenging. This work aims [...] Read more.
Soft tissues exhibit remarkable stretchability, fracture toughness, and stress–relaxation ability. They possess a large water content to support cellular processes. Mimicking such a combination of mechanical and physical properties in hydrogels is important for tissue engineering applications but remains challenging. This work aims to develop a hydrogel that can combine excellent mechanical properties with cellular viability. The research focused on polyvinyl alcohol (PVA)/agar double-network (DN) hydrogels, fabricated by thermal gelation and freeze–thawing methods. Their mechanical properties were characterized through tension, compression, fracture, and stress–relaxation tests, and their cellular viability was measured through cytotoxicity tests. The results show that the PVA/agar DN gels are highly stretchable (>200%) and compressible (>30%) while containing high water content. The incorporation of agar by 6 wt% improved the fracture toughness of hydrogels from 1 to 1.76 kJ/m2. The degree of stress–relaxation, a key indicator of gel viscoelastic properties, improved by roughly 170% with an increase in agar content from 0 to 6 wt%. Cytotoxicity analysis showed that the gels, being physically cross-linked, were able to promote cellular proliferation. This work shows that tough and viscoelastic PVA/agar DN gels are suitable for soft tissue engineering applications, especially cartilage repair. Full article
(This article belongs to the Section Gel Analysis and Characterization)
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22 pages, 19211 KB  
Article
The Impact of Earth-Based Building in Residential Environments on Human Emotional Relief Using EEG + VR + LEC Method
by Junjie Li, Ziyi Liu, Xuewen Zhang, Yujie Chen and Shuai Lu
Buildings 2025, 15(18), 3280; https://doi.org/10.3390/buildings15183280 - 11 Sep 2025
Viewed by 436
Abstract
Urbanization exacerbates mental health challenges, prompting the exploration of biophilic design solutions. This study examined the therapeutic potential of raw earth through its thermal interactions in architecture. First, energy consumption simulations established distinct indoor temperature ranges for raw earth, concrete, and steel under [...] Read more.
Urbanization exacerbates mental health challenges, prompting the exploration of biophilic design solutions. This study examined the therapeutic potential of raw earth through its thermal interactions in architecture. First, energy consumption simulations established distinct indoor temperature ranges for raw earth, concrete, and steel under identical energy constraints: low (22.8 ± 0.32 °C), medium (26.5 ± 0.39 °C), and high (30.1 ± 0.84 °C). The study then quantified the differences in physical and psychological perceptions across material-dominated spaces under controlled temperatures above. Nine scenes were constructed for emotional healing evaluation, incorporating the olfactory dimension into the Electroencephalogram (EEG) + Virtual reality (VR) + Laboratory environmental control (LEC) approach. The results indicated that raw earth materials were most effective in promoting emotional recovery under thermal stress conditions (low/high temperatures), as evidenced by a significant enhancement of α EEG rhythms. However, under moderate conditions, concrete environments produced the greatest relaxation effects, while steel environments were most conducive to enhancing focus. The core conclusion of this study is that the therapeutic effects of building materials are not static but are intricately linked to the surrounding thermal environment. This provides a new perspective for evidence-based healthy building design and underscores the importance of optimizing material selection based on specific environmental conditions and needs. Full article
(This article belongs to the Section Building Energy, Physics, Environment, and Systems)
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12 pages, 1983 KB  
Article
Non-Destructive Evaluation of HTV’s Thermal-Oxidative Aging Using Terahertz Dielectric Spectroscopy
by Tengyi Zhang, Li Cheng, Shuo Zhang, Bo Tao and Yipu Tang
Materials 2025, 18(17), 4176; https://doi.org/10.3390/ma18174176 - 5 Sep 2025
Viewed by 748
Abstract
Thermal oxidative aging failure of high-temperature vulcanized silicone rubber (HTV) in high-voltage insulators is the core hidden danger of power grid security. In this study, terahertz time domain spectroscopy (THz-TDS) and attenuated total reflection infrared spectroscopy (ATR-FTIR) were combined to reveal the quantitative [...] Read more.
Thermal oxidative aging failure of high-temperature vulcanized silicone rubber (HTV) in high-voltage insulators is the core hidden danger of power grid security. In this study, terahertz time domain spectroscopy (THz-TDS) and attenuated total reflection infrared spectroscopy (ATR-FTIR) were combined to reveal the quantitative structure–activity relationship between dielectric response and chemical group evolution of HTV during accelerated aging at 200 °C for 80 days. In this study, HTV flat samples were made in the laboratory, and the dielectric spectrum of HTV in the range of 0.1 THz to 0.4 THz was extracted by a terahertz time–domain spectrum platform. ATR-FTIR was used to analyze the functional group change trend of HTV during aging, and the three-stage evolution of the dielectric real part (0.16 THz), the dynamics of the carbonyl group, the monotonic rise of the dielectric imaginary part (0.17 THz), and the linear response of silicon-oxygen bond breaking were obtained by combining the double Debye relaxation theory. Finally, three aging stages of HTV were characterized by dielectric loss angle data. The model can warn about the critical point of early oxidation and main chain fracture and identify the risk of insulation failure in advance compared with traditional methods. This study provides a multi-scale physical basis for nondestructive life assessment in a silicon rubber insulator. Full article
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