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Keywords = rupture discs

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37 pages, 60981 KB  
Article
Numerical Simulation and Analysis of the Manufacturing Process of Pre-Bulged Rupture Discs
by Benjamin Treude, Denis Anders and Kerstin Weinberg
Appl. Sci. 2024, 14(21), 9731; https://doi.org/10.3390/app14219731 - 24 Oct 2024
Cited by 3 | Viewed by 1655
Abstract
Rupture discs, also known as bursting discs, are indispensable components in fluid-operated systems providing effective protection against hazardous over-pressure or partial vacuum. They belong to a special class of safety devices and are found in a variety of technical applications including pressure vessels, [...] Read more.
Rupture discs, also known as bursting discs, are indispensable components in fluid-operated systems providing effective protection against hazardous over-pressure or partial vacuum. They belong to a special class of safety devices and are found in a variety of technical applications including pressure vessels, piping systems, reactors and boilers. In all application scenarios, rupture discs act as sacrificial parts that have to fail precisely at a predetermined differential pressure, opening a relief flow path for the working fluid. The membrane employed within rupture discs is usually made out of specific metal alloys or different material layers depending on the particular application. However, for many manufacturers of rupture discs, the production process is characterized by a lack of systematic procedures, relying instead on trial and error as well as empirical values. By means of thorough finite-element-based modeling and simulation of the bulge-forming process of rupture discs, including an elastic–plastic material law, large deformation, as well as contact mechanics, it is possible to accurately predict the resulting stress–strain behavior. All simulation results are rigorously validated through corresponding experiments conducted during the bulge-forming process. Therefore, this contribution provides a reliable basis for the parameter set-up during the manufacturing process of rupture discs. Full article
(This article belongs to the Section Mechanical Engineering)
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29 pages, 10907 KB  
Review
The Progress of Autoignition of High-Pressure Hydrogen Gas Leakage: A Comprehensive Review
by Gan Cui, Yixuan Li, Di Wu, Hongwei Li, Huan Liu, Xiao Xing and Jianguo Liu
Fire 2024, 7(8), 268; https://doi.org/10.3390/fire7080268 - 2 Aug 2024
Cited by 6 | Viewed by 4949
Abstract
As a paradigm of clean energy, hydrogen is gradually attracting global attention. However, its unique characteristics of leakage and autoignition pose significant challenges to the development of high-pressure hydrogen storage technologies. In recent years, numerous scholars have made significant progress in the field [...] Read more.
As a paradigm of clean energy, hydrogen is gradually attracting global attention. However, its unique characteristics of leakage and autoignition pose significant challenges to the development of high-pressure hydrogen storage technologies. In recent years, numerous scholars have made significant progress in the field of high-pressure hydrogen leakage autoignition. This paper, based on diffusion ignition theory, thoroughly explores the mechanism of high-pressure hydrogen leakage autoignition. It reviews the effects of various factors such as gas properties, burst disc rupture conditions, tube geometric structure, obstacles, etc., on shock wave growth patterns and autoignition characteristics. Additionally, the development of internal flames and propagation characteristics of external flames after ignition kernels generation are summarized. Finally, to promote future development in the field of high-pressure hydrogen energy storage and transportation, this paper identifies deficiencies in the current research and proposes key directions for future research. Full article
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16 pages, 2368 KB  
Article
An Assessment of Some Mechanical Properties of Harvested Potato Tubers cv. Spunta
by Saad S. Almady, Saad A. Al-Hamed, Samy A. Marey, Saleh M. Al-Sager and Abdulwahed M. Aboukarima
Agronomy 2024, 14(6), 1116; https://doi.org/10.3390/agronomy14061116 - 23 May 2024
Cited by 5 | Viewed by 2264
Abstract
Mechanical properties of vegetables or crop materials play a noteworthy part in designing new related implements. These properties can be extracted from force–deformation curves. Several factors, such as soil preparation, irrigation, and pre- and post-harvest treatments influence them. The core objective of this [...] Read more.
Mechanical properties of vegetables or crop materials play a noteworthy part in designing new related implements. These properties can be extracted from force–deformation curves. Several factors, such as soil preparation, irrigation, and pre- and post-harvest treatments influence them. The core objective of this investigation work was to analyze force–deformation curves obtained from compression, penetration, and shear tests of potatoes (Spunta cv.) produced with three tillage implements. The potatoes cv. Spunta were cultivated in loamy sand soil under the center-pivot irrigation system. The tillage implements used were a disc harrow plow, chisel plow, and moldboard plow. The trials were performed at a constant planting depth (15 cm) below the soil and a single plowing speed of 5.4 km/h. All data were expressed as an average of five replicates ± standard deviation. The force–deformation curves analysis showed that the modulus of elasticity for potatoes cv. Spunta ranged from 4.32 to 5.8 N/mm, the bioyield force ranged from 84.25 to 114.12 N, and rupture forces ranged from 100.90 to 139.78 N. Furthermore, the results showed that the average values of the elastic and plastic ranges were 3.0 and 2.1 mm, respectively. The mean value of hardness was 1671.53 N·mm. No significant differences were observed with respect to the two planting seasons, but tillage implements had a significant impact on the characteristics extracted from the compression tests. The mean of the maximum forces required to penetrate the potato during the penetration stage were 41.24 N, 44.86 N, and 47.16 N for potatoes produced with the disc harrow plow, chisel plow, and moldboard plow, respectively. Similarly, the means of the maximum forces required to cut the potato in the shear stage were 724.38 N, 761 N, and 773.43 N for the disc harrow plow, chisel plow, and moldboard plow, respectively. The force–deformation curves showed that additional information might be required to obtain a complete description of the potato quality necessary to harvest potatoes cv. Spunta using harvesting and handling equipment with reduced economic loss. An extensive study of the soil characteristics and the above-mentioned properties is also recommended. The results obtained about the mechanical characteristics of potatoes cv. Spunta can be useful in providing information that aids in designing potato harvesting machines and in potato products factories. Full article
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26 pages, 4899 KB  
Article
Innovative Early Detection of High-Temperature Abuse of Prismatic Cells and Post-Abuse Degradation Analysis Using Pressure and External Fiber Bragg Grating Sensors
by André Hebenbrock, Nury Orazov, Ralf Benger, Wolfgang Schade, Ines Hauer and Thomas Turek
Batteries 2024, 10(3), 92; https://doi.org/10.3390/batteries10030092 - 4 Mar 2024
Cited by 9 | Viewed by 3576
Abstract
The increasing adoption of lithium-ion battery cells in contemporary energy storage applications has raised concerns regarding their potential hazards. Ensuring the safety of compact and modern energy storage systems over their operational lifespans necessitates precise and dependable monitoring techniques. This research introduces a [...] Read more.
The increasing adoption of lithium-ion battery cells in contemporary energy storage applications has raised concerns regarding their potential hazards. Ensuring the safety of compact and modern energy storage systems over their operational lifespans necessitates precise and dependable monitoring techniques. This research introduces a novel method for the cell-specific surveillance of prismatic lithium-ion cells, with a focus on detecting pressure increases through the surface application of a fiber Bragg grating (FBG) sensor on a rupture disc. Commercially available prismatic cells, commonly used in the automotive sector, are employed as test specimens and equipped with proven pressure and innovative FBG sensors. Encompassing the analysis capacity, internal resistance, and pressure (under elevated ambient temperatures of up to 120 °C), this investigation explores the thermal degradation effects. The applied FBG sensor on the rupture disc exhibits reversible and irreversible state changes in the cells, offering a highly sensitive and reliable monitoring solution for the early detection of abuse and post-abuse cell condition analysis. This innovative approach represents a practical implementation of fiber optic sensor technology that is designed for strain-based monitoring of prismatic lithium-ion cells, thereby enabling customized solutions through which to address safety challenges in prismatic cell applications. In alignment with the ongoing exploration of lithium-ion batteries, this research offers a customizable addition to battery monitoring and fault detection. Full article
(This article belongs to the Special Issue Thermal Safety of Lithium Ion Batteries)
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4 pages, 1659 KB  
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Traumatic Anterior Cervical Disc Herniation Presenting as Severe Dysphagia
by Jonghun Seo, Jeonghyun Oh, Pius Kim, Chang Il Ju and Seok Won Kim
Diagnostics 2023, 13(24), 3644; https://doi.org/10.3390/diagnostics13243644 - 12 Dec 2023
Cited by 1 | Viewed by 2079
Abstract
Due to the anatomical characteristics of the cervical spine, few cases of traumatic anterior cervical disc herniation have been reported in the literature. Here, we present a rare case of a traumatic anterior cervical disc herniation presenting as severe dysphagia. A 75-year-old male [...] Read more.
Due to the anatomical characteristics of the cervical spine, few cases of traumatic anterior cervical disc herniation have been reported in the literature. Here, we present a rare case of a traumatic anterior cervical disc herniation presenting as severe dysphagia. A 75-year-old male patient presented with severe dysphagia following an accident three days prior when he fell from a height of stairs. Cervical magnetic resonance (MR) imaging revealed a 1.3 × 1.0 cm extruded disc in the anterior aspect of the C4 level with the base at the C3–4 disc, which displaced the esophagus anteriorly. Esophagography revealed an extrinsic esophageal lesion that was considered to be responsible for the obstruction of the airway at the same level. He underwent a ruptured disc removal via the anterior approach. Preoperative dysphagia was resolved gradually after surgery, and he remained asymptomatic six months after surgery. Full article
(This article belongs to the Section Medical Imaging and Theranostics)
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19 pages, 16099 KB  
Article
The Effect of Forging and Heat Treatment Variables on Microstructure and Mechanical Properties of a Re-Bearing Powder-Metallurgy Nickel Base Superalloy
by Shamil Mukhtarov, Dmitry Karyagin, Artem Ganeev, Rishat Zainullin, Ruslan Shakhov and Valery Imayev
Metals 2023, 13(6), 1110; https://doi.org/10.3390/met13061110 - 13 Jun 2023
Cited by 4 | Viewed by 2463
Abstract
In our previous works, the effects of forging and heat treatment variables on microstructure evolution and mechanical properties have been studied for an ingot-metallurgy Re-bearing nickel base superalloy. To overcome the issues associated with the production of large-scale ingots and fine-grained workpieces, in [...] Read more.
In our previous works, the effects of forging and heat treatment variables on microstructure evolution and mechanical properties have been studied for an ingot-metallurgy Re-bearing nickel base superalloy. To overcome the issues associated with the production of large-scale ingots and fine-grained workpieces, in the present work, the effect of hot forging and heat treatment variables was studied in a Re-bearing nickel base superalloy prepared via powder metallurgy. The purpose of the study was to reach the properly balanced mechanical properties for the potential use of the superalloy as a disc material. The initial as-HIPed workpieces were subjected to different hot forging and post-forging heat treatment or only to heat treatment (no forging). For the processed workpieces, the recrystallization behavior, size, morphology and volume fraction of γ′ precipitates were evaluated by scanning electron microscopy followed by a study of mechanical properties. The most properly balanced mechanical properties (strength, ductility, creep resistance and creep rupture lifetime) were reached for the γ grain size of dγ ≈ 13.6 µm. A finer and coarser γ grain size (down to dγ ≈ 2.6 and up to dγ ≈ 37.5 µm) even when superimposed with a higher volume fraction of dispersed secondary γ′ precipitates (in the case of dγ = 27–37.5 µm) was associated with worse mechanical properties. Full article
(This article belongs to the Special Issue Characterization and Processing Technology of Superalloys)
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17 pages, 1196 KB  
Review
Role of Pyroptosis in Intervertebral Disc Degeneration and Its Therapeutic Implications
by Jieya Luo, Yuxuan Yang, Xuan Wang, Xingyu Chang and Songbo Fu
Biomolecules 2022, 12(12), 1804; https://doi.org/10.3390/biom12121804 - 2 Dec 2022
Cited by 39 | Viewed by 3299
Abstract
Intervertebral disc degeneration (IDD), a progressive and multifactorial pathological process, is predominantly associated with low back pain and permanent disability. Pyroptosis is a type of lytic programmed cell death triggered by the activation of inflammasomes and caspases. Unlike apoptosis, pyroptosis is characterized by [...] Read more.
Intervertebral disc degeneration (IDD), a progressive and multifactorial pathological process, is predominantly associated with low back pain and permanent disability. Pyroptosis is a type of lytic programmed cell death triggered by the activation of inflammasomes and caspases. Unlike apoptosis, pyroptosis is characterized by the rupture of the plasma membrane and the release of inflammatory mediators, accelerating the destruction of the extracellular matrix (ECM). Recent studies have shown that pyrin domain-containing 3 (NLRP3) inflammasome-mediated pyroptosis in nucleus pulposus (NP) cells is activated in the progression of IDD. Furthermore, targeting pyroptosis in IDD demonstrates the excellent capacity of ECM remodeling and its anti-inflammatory properties, suggesting that pyroptosis is involved in the IDD process. In this review, we briefly summarize the molecular mechanism of pyroptosis and the pathogenesis of IDD. We also focus on the role of pyroptosis in the pathological progress of IDD and its targeted therapeutic application. Full article
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18 pages, 53297 KB  
Article
Research of Dynamic Tensile Properties of Five Rocks under Three Loading Modes Based on SHPB Device
by Diyuan Li, Jinyin Ma, Quanqi Zhu and Bang Li
Materials 2022, 15(23), 8473; https://doi.org/10.3390/ma15238473 - 28 Nov 2022
Cited by 8 | Viewed by 2400
Abstract
The validity of calculating the dynamic tensile strength of rock materials based on dynamic Brazilian tests is problematic. In order to gain a deeper understanding of the effects of three typical loading methods on the damage mechanism of rock specimens in the dynamic [...] Read more.
The validity of calculating the dynamic tensile strength of rock materials based on dynamic Brazilian tests is problematic. In order to gain a deeper understanding of the effects of three typical loading methods on the damage mechanism of rock specimens in the dynamic Brazilian tests, five different rocks were selected for the study. In the constant incident energy dynamic Brazilian test, the loading modes had a significant effect on the loading rate and dynamic tensile strength of the specimen, with the highest loading rate and tensile strength of the specimens under mode-III loading, followed by mode-I loading and mode-II loading. A high-speed camera and the digital image correlation (DIC) technique were used to successfully capture the rupture process of the Brazilian disc during impact loading. The evolution of the displacement and strain fields of the specimen was obtained by DIC technique, and four typical failure patterns and two rupture characteristics in the dynamic Brazilian test were summarized. The loading mode determined the crack initiation position of the specimen in the dynamic Brazilian test. The results showed that the mode-III loading is the most consistent with the Brazilian test theory, while the mode-II loading violates the test principle. Full article
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15 pages, 25095 KB  
Article
Determination of the Plastic Stress–Strain Relationship of a Rupture Disc Material with Quasi-Static and Dynamic Pneumatic Bulge Processes
by Xiaozhe Yu, Xingqing Yan, Yue Li, Fangchi Zeng, Shouli Kang and Jianliang Yu
Processes 2022, 10(8), 1463; https://doi.org/10.3390/pr10081463 - 26 Jul 2022
Cited by 5 | Viewed by 2625
Abstract
Rupture discs, manufactured using a hydraulic or pneumatic bulge process, are widely used to protect vessels from over-pressuring. The stress–strain relationship of the material in the bulge process plays a major role in understanding the performance of rupture discs. Moreover, both the theoretical [...] Read more.
Rupture discs, manufactured using a hydraulic or pneumatic bulge process, are widely used to protect vessels from over-pressuring. The stress–strain relationship of the material in the bulge process plays a major role in understanding the performance of rupture discs. Moreover, both the theoretical analyses and numerical simulations of rupture discs demand a reliable stress–strain relationship of the material in a real bulge process. In this paper, an approach for determining the plastic stress–strain relationship of a rupture disc material in the bulge process is proposed based on plastic membrane theory and force equilibrium equations. Pressures of compressed air and methane/air mixture explosions were used for the bulge pressure to accomplish the quasi-static and dynamic bulge processes of tested discs. Experimental apparatus for the quasi-static bulge test and the dynamic bulge test were built. The stress–strain relations of 316L material during bulge tests were obtained, compared, and discussed. The results indicated that the bulge height at the top of the domed disc increased linearly with an increase in bulge pressure in the quasi-static and dynamic bulge processes, and the effective strain increased exponentially. The rate of pressure rise during the bulge process has a significant effect on the deformation behavior of disc material and hence the stress–strain relationship. At the same bulge pressure, a disc tested with a larger pressure rise rate had smaller bulge height and effective strain. At the same effective stress at the top of the domed disc, discs subjected to a higher pressure rise rate had smaller effective strain, and hence they are more difficult to rupture. Hollomon’s equation is used to represent the relationship between the effective stress and strain during bulge process. For pressure rise rates in the following range of 0 (equivalent to quasi-static condition), 2–10 MPa/s, 10–50 MPa/s, and 50–100 MPa/s, the relation of stress and strain is σe = 1259.4·εe0.4487, σe = 1192.4·εe0.3261, σe = 1381.2·εe0.2910, and σe = 1368.4·εe0.1701, respectively. Full article
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16 pages, 268 KB  
Article
A Cross-Sectional Descriptive Study of Musculoskeletal Disorders (MSDs) of Male Shipbuilding Workers and Factors Associated the Neck, Shoulder, Elbow, Low Back, or Knee MSDs
by Woo-Jin Kim, Hyun-Jin Park and Byung-Yong Jeong
Appl. Sci. 2022, 12(7), 3346; https://doi.org/10.3390/app12073346 - 25 Mar 2022
Cited by 7 | Viewed by 2803
Abstract
This study investigates the cross-sectional descriptive characteristics of male shipbuilding workers’ musculoskeletal disorders (MSDs) and factors associated with MSDs in the neck, shoulders, elbows, low back, or knees. From the national compensation data confirmed as MSDs during three years between 2015 and 2017, [...] Read more.
This study investigates the cross-sectional descriptive characteristics of male shipbuilding workers’ musculoskeletal disorders (MSDs) and factors associated with MSDs in the neck, shoulders, elbows, low back, or knees. From the national compensation data confirmed as MSDs during three years between 2015 and 2017, 985 male workers were analyzed in terms of age, work experience, occupations, company size, and MSD type according to each body region. In the analysis of frequency and severity according to ‘occupation–body region–MSD type’, ‘Electrician/plumber–low back–herniated disc’ (6.9%) was the form of MSDs with the highest frequency among total MSDs, and ‘Crane–neck–herniated disc’ (500.5 days) was the highest mean of sick leave days. The low back MSDs (28.9%) were the highest frequency, followed by shoulders (27.7%) and knees (16.2%). The herniated disc was frequent in the neck and lumbar region, and the mean of sick leave days of the neck herniated disc (402.2 days) was greater than that of the low back herniated disc (321.1 days). While a rupture was frequent in the shoulder or knee region, the mean of sick leave days for shoulder rupture (335.1 days) was greater than that of the knee rupture (318.8 days). In the binary logistic regression analysis, age was positively associated with MSDs in the neck, shoulder, or elbow regions, while the low back MSDs category was not positively associated with age. Large companies with >1000 employees were highly associated with neck MSDs, while small companies with <30 employees were related to the low back MSDs. This study derives the characteristics for frequency and sick leave days of MSDs in the neck, shoulders, elbows, low back, or knees to prioritize MSD prevention information. The results of this study can be used as primary data for establishing MSD prevention policy. Full article
(This article belongs to the Special Issue State-of-the-Art in Human Factors and Interaction Design)
14 pages, 3946 KB  
Article
Creep Behavior of Compact γ′-γ″ Coprecipitation Strengthened IN718-Variant Superalloy
by Semanti Mukhopadhyay, Hariharan Sriram, Christopher H. Zenk, Richard DiDomizio, Andrew J. Detor, Robert W. Hayes, Gopal B. Viswanathan, Yunzhi Wang and Michael J. Mills
Metals 2021, 11(12), 1897; https://doi.org/10.3390/met11121897 - 25 Nov 2021
Cited by 5 | Viewed by 4050
Abstract
The development of high-temperature heavy-duty turbine disk materials is critical for improving the overall efficiency of combined cycle power plants. An alloy development strategy to this end involves superalloys strengthened by ‘compact’ γ′-γ″ coprecipitates. Compact morphology of coprecipitates consists of [...] Read more.
The development of high-temperature heavy-duty turbine disk materials is critical for improving the overall efficiency of combined cycle power plants. An alloy development strategy to this end involves superalloys strengthened by ‘compact’ γ′-γ″ coprecipitates. Compact morphology of coprecipitates consists of a cuboidal γ′ precipitate such that γ″ discs coat its six {001} faces. The present work is an attempt to investigate the microstructure and creep behavior of a fully aged alloy exhibiting compact coprecipitates. We conducted heat treatments, detailed microstructural characterization, and creep testing at 1200 °F (649 °C) on an IN718-variant alloy. Our results indicate that aged IN718-27 samples exhibit a relatively uniform distribution of compact coprecipitates, irrespective of the cooling rate. However, the alloy ruptured at low strains during creep tests at 1200 °F (649 °C). At 100 ksi (689 MPa) load, the alloy fails around 0.1% strain, and 75 ksi (517 MPa) loading causes rupture at 0.3% strain. We also report extensive intergranular failure in all the tested samples, which is attributed to cracking along grain boundary precipitates. The results suggest that while the compact coprecipitates are indeed thermally stable during thermomechanical processing, the microstructure of the alloy needs to be optimized for better creep strength and rupture life. Full article
(This article belongs to the Special Issue Creep Behavior of Metals and Alloys)
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18 pages, 74058 KB  
Article
Influence of Moulding Pressure on the Burst Pressure of Reverse-Acting Rupture Discs
by Lili Liu, Chenxing Yuan, Wei Li, Beibei Li and Xiumei Liu
Processes 2021, 9(10), 1775; https://doi.org/10.3390/pr9101775 - 4 Oct 2021
Cited by 5 | Viewed by 4728
Abstract
Rupture discs, also called bursting discs, are widely used in pressure vessels, pressure equipment, and pressure piping in process industries, such as nuclear power, fire protection, and petrochemical industries. To explore the relationship between the burst pressure of reverse-acting rupture discs and their [...] Read more.
Rupture discs, also called bursting discs, are widely used in pressure vessels, pressure equipment, and pressure piping in process industries, such as nuclear power, fire protection, and petrochemical industries. To explore the relationship between the burst pressure of reverse-acting rupture discs and their production, two common manufacturing methods, air pressure moulding and hydraulic moulding, were compared in this study. Reverse-acting rupture discs that complied with the form recommended by API 520-2014 were prepared with four release diameters, and burst pressure tests were carried out. These results showed an obvious negative correlation between the forming pressure of rupture discs and their actual burst pressure for all experimental samples. Further study showed that the main reason for this correlation was a reduction in thickness at the top of the rupture disc caused by large plastic deformation during compression moulding. To explore the relationship between the thickness reduction effect and moulding method, this study defined the “relative ratio of thickness reduction” and concluded that the effect of decreasing the thickness of the rupture disc was more obvious for rupture disc substrates with less flexural rigidity. The above conclusions have important significance for guiding the control of the burst pressure of rupture discs. Full article
(This article belongs to the Topic Modern Technologies and Manufacturing Systems)
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12 pages, 3943 KB  
Article
Prediction of Neural Space Narrowing and Soft Tissue Injury of the Cervical Spine Concerning Head Restraint Arrangements in Traffic Collisions
by Othman Laban, Elsadig Mahdi and John-John Cabibihan
Appl. Sci. 2021, 11(1), 145; https://doi.org/10.3390/app11010145 - 25 Dec 2020
Viewed by 2449
Abstract
Common quantitative assessments of neck injury criteria do not predict anatomical neck injuries and lack direct relations to design parameters of whiplash-protection systems. This study aims to provide insights into potential soft tissue-level injury sites based on the interactions developed in-between different anatomical [...] Read more.
Common quantitative assessments of neck injury criteria do not predict anatomical neck injuries and lack direct relations to design parameters of whiplash-protection systems. This study aims to provide insights into potential soft tissue-level injury sites based on the interactions developed in-between different anatomical structures in case of a rear-end collision. A detailed finite element human model has exhibited an excellent biofidelity when validated against volunteer impacts. Three head restraint arrangements were simulated, predicting both the kinematic response and the anatomical pain source at each arrangement. Head restraint’s contribution has reduced neck shear and head kinematics by at least 70 percent, minimized pressure gradients acting on ganglia and nerve roots less than half. Posterior column ligaments were the most load-bearing components, followed by the lower intervertebral discs and upper capsular ligaments. Sprain of the interspinous ligamentum flavum at early stages has caused instability in the craniovertebral structure causing its discs and facet joints to be elevated compressive loads. Excessive hyperextension motion, which occurred in the absence of the head restraint, has promoted a stable avulsion teardrop fracture of the fourth vertebral body’s anteroinferior aspect and rupture the anterior longitudinal ligament. The observed neck injuries can be mathematically related to head–torso relative kinematics. These relations will lead to the development of a comprehensive neck injury criterion that can predict the injury level. This, in turn, will impose a significant impact on the design processes of vehicle anti-whiplash safety equipment. Full article
(This article belongs to the Section Applied Biosciences and Bioengineering)
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14 pages, 906 KB  
Article
Is ECLIA Serum Cortisol Concentration Measurement, an Accurate Indicator of Pain Severity in Dogs with Locomotor Pain?
by Adela Katalin Markovszky, Corinna Weber, Otília Biksi, Mihai Danes, Eugenia Dumitrescu, Florin Muselin, Vincenzo Tufarelli, Nikola Puvača and Romeo Teodor Cristina
Animals 2020, 10(11), 2036; https://doi.org/10.3390/ani10112036 - 4 Nov 2020
Cited by 11 | Viewed by 4608
Abstract
The purpose of determining serum cortisol level is to reflect the activity of stress axis, ethological alterations, acute and chronic pain, life quality, or psychogenic stress. Although it is stated that stress can produce a measurable influence on the cortisol level, a certified [...] Read more.
The purpose of determining serum cortisol level is to reflect the activity of stress axis, ethological alterations, acute and chronic pain, life quality, or psychogenic stress. Although it is stated that stress can produce a measurable influence on the cortisol level, a certified value of this pain biomarker in dogs was not generally accepted yet. This study aimed to investigate if serum cortisol measured follows allopathic treatments only, or it is associated with physiotherapy, point out pain level in dogs with orthopedic disease, which could reveal the healing progress. The diagnostic identified: hip dysplasia, cranial cruciate ligament rupture, or intervertebral disc disease. Ortolani and Barden tests, together with clinical examination, drawer sign, and tibia compression test, were done in dogs exhibiting postures, and motion alteration, and X-Ray confirmed. A total of 30 dogs were grouped in healthy (n = 10) and pain groups (n = 20), the blood sampling is done at the beginning of the investigation, and after ten days of the study. Dogs were handled in two ways: G1—treated with Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) only and respectively, G2—by therapy and physiotherapy. The analysis was performed on a Roche Cobas Analyzer (Roche, USA), serum cortisol being determined by Electrochemiluminescence immunoassay (ECLIA), and statistics using ANOVA, following Tukey’s Multiple Comparison Test. The results revealed that, out of ten specimens in the Control group, nine were within the normal limits: 5–65 ng × mL−1 (24.76 ± 19.48678), and one sample under the set limit. In G1, it was observed that the plasmatic P1 values were below the levels of P2, in six situations. In G2, although the status of all subjects improved radically with the removal or evident reduction of pain, confirmed clinically and imagistically, the P2 values in five dogs were higher than the initial P1 values, and in contradiction with the observed clinical reality. Comparing results, the mean difference in G1 was 0.41, and in G2 = 2.54, with an SD for G1 = 13.38, and G2 = 16.66, registering moderate development. Standard deviation illustrated that the values of treated groups were highly spread throughout the interval, and the serum cortisol assay did not generate significant statistical differences between groups in our case. This inferred the doubt whether the used detection method or values registered correctly indicates the pain levels in dog species. Full article
(This article belongs to the Section Veterinary Clinical Studies)
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9 pages, 5776 KB  
Article
Fully Endoscopic Transforaminal Lumbar Discectomy for Upward Migration of Upper Lumbar Disc Herniation: Clinical and Radiological Outcomes and Technical Considerations
by Dong Hwa Heo, Dong Keun Lee, Dong Chan Lee, Hyeun Sung Kim and Choon Keun Park
Brain Sci. 2020, 10(6), 363; https://doi.org/10.3390/brainsci10060363 - 10 Jun 2020
Cited by 13 | Viewed by 4452
Abstract
Microdiscectomy for the upward migration of upper lumbar herniated discs has a high risk of isthmus and facet injury. Fully endoscopic transforaminal discectomy can preserve normal bony structures during discectomy. The purpose of this study was to assess the clinical and radiological outcomes [...] Read more.
Microdiscectomy for the upward migration of upper lumbar herniated discs has a high risk of isthmus and facet injury. Fully endoscopic transforaminal discectomy can preserve normal bony structures during discectomy. The purpose of this study was to assess the clinical and radiological outcomes of fully endoscopic transforaminal discectomy for upward migrated upper lumbar herniated discs. All patients had upward migrated disc herniation from L1–L2 to L3–L4 levels and were treated using fully endoscopic transforaminal discectomy under local anesthesia. All enrolled patients were monitored for more than 12 months. Clinical outcomes were assessed using the Oswestry Disability Index (ODI) and visual analog scale (VAS) of pain. Surgery-related complications were analyzed. In addition, radiological outcomes were investigated using postoperative magnetic resonance imaging (MRI) and lumbar dynamic X-ray. Twenty-eight patients were enrolled in this study. ODI and VAS significantly decreased after endoscopic transforaminal discectomy. Migrated ruptured disc particles were completely removed and confirmed on postoperative MRI in 26 of the 28 patients. Even though small remnant disc particles were detected in two patients, symptoms improved after endoscopic transforaminal discectomy. Early recurrence of herniated disc occurred at the operated segment in one patient. There were no significant complications associated with fully endoscopic transforaminal discectomy. Three patients experienced a postoperative transient tingling sensation and numbness of the leg. Fully endoscopic transforaminal lumbar discectomy may be an effective and alternative treatment option for upward migrated disc herniation in the upper lumbar area. In addition, fully endoscopic transforaminal lumbar discectomy may prevent complications associated with general endotracheal anesthesia and injuries of the isthmus and the facet joint. Full article
(This article belongs to the Special Issue Degenerative Spinal Disease)
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