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14 pages, 2327 KB  
Article
Safety and Efficacy Evaluation of Ultrasound Aspirators in Intramedullary Spinal Cord Tumors Surgery: An Experimental Study on a Swine Model
by Mauro Palmieri, Alessandro Pesce, Mattia Capobianco, Massimo Corsini, Giorgia Iovannitti, Fulvio Aloj, Giuseppa Zancana, Vincenzo Esposito, Maurizio Salvati, Antonio Santoro, Gianpaolo Cantore and Alessandro Frati
Brain Sci. 2025, 15(7), 670; https://doi.org/10.3390/brainsci15070670 - 21 Jun 2025
Viewed by 618
Abstract
Introduction: Intradural extramedullary and intramedullary spinal tumors are rare, complex to treat, and require advanced surgical techniques. Ultrasonic aspirators, commonly used for tumor removal, can cause sensory and motor deficits, including loss of motor evoked potentials (MEPs). This study aims to evaluate [...] Read more.
Introduction: Intradural extramedullary and intramedullary spinal tumors are rare, complex to treat, and require advanced surgical techniques. Ultrasonic aspirators, commonly used for tumor removal, can cause sensory and motor deficits, including loss of motor evoked potentials (MEPs). This study aims to evaluate the safety and efficacy of ultrasonic aspirators in intramedullary tumor surgery using a swine model, comparing different systems and techniques. Methods: Ten pigs underwent D1-D3 laminectomy and myelotomy, with adipose tissue simulating a tumor. The ultrasonic aspirators were tested under varying conditions (fragmentation power, suction, application time, and vibration mode). The primary endpoint is to evaluate the impact of the chosen variables on motor function damage. The secondary endpoints are histological evaluation of the type of damage caused by ultrasound aspirators and the effect of steroid drugs on MEPs’ impairment recovery. Results: Ultrasound aspirators can cause a significant MEP signal reduction when used in continuous mode, with fragmentation power >30 for more than 2 min (p < 0.001). Suction does not affect MEPs. When used in alternating/pulsatile mode, fragmentation power and application time do not affect MEPs. The two-way ANOVA analysis on the interaction between fragmentation power and application time in continuous mode did not demonstrate a significant interaction (p = 0.155). Time alone does not affect motor damage (p = 0.873). Betamethasone can restore MEPs’ signal after damage if administered immediately. Conclusions: Using ultrasonic aspirators in an animal model of intramedullary tumor surgery is safe. The main factor that resulted in the responsibility of motor function impairment is the fragmentation power. Full article
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12 pages, 560 KB  
Article
Cerebral Near-Infrared Spectroscopy and Electrical Cardiometry During Endotracheal Suction in Ventilated Infants Following Surgery: A Feasibility Study
by Matthias Nissen and Ralf-Bodo Tröbs
Life 2025, 15(6), 901; https://doi.org/10.3390/life15060901 - 31 May 2025
Cited by 1 | Viewed by 809
Abstract
Background: Near-Infrared Spectroscopy (NIRS) and Electrical Cardiometry (EC) are promising non-invasive techniques for monitoring tissue oxygenation and hemodynamics, particularly in surgically ill infants who struggle to maintain cerebral oxygenation and systemic perfusion. There is limited data regarding the combined use of these techniques [...] Read more.
Background: Near-Infrared Spectroscopy (NIRS) and Electrical Cardiometry (EC) are promising non-invasive techniques for monitoring tissue oxygenation and hemodynamics, particularly in surgically ill infants who struggle to maintain cerebral oxygenation and systemic perfusion. There is limited data regarding the combined use of these techniques during respiratory procedures such as endotracheal suction in intubated infants. Methods: The effects of 38 endotracheal suction maneuvers on cerebral oxygenation and cardiovascular hemodynamics were investigated in seven intubated infants following non-cardiac surgery. Parameters such as cerebral oxygenation and EC-derived metrics including heart rate, stroke volume, and cardiac output were assessed. Results: Gestational and postnatal age were 31 weeks and 16 days. During endotracheal suction, the heart rate decreased but returned to baseline afterward. After the procedure, the cerebral oxygenation, stroke volume, and cardiac output increased. Conclusions: Cerebral and systemic hemodynamics were altered during endotracheal suction maneuvers in ventilated infants. Combining NIRS and EC for monitoring cardiovascular and cerebrovascular physiology may enable more individualized therapy, helping to minimize cerebral injury in this vulnerable population. Full article
(This article belongs to the Section Medical Research)
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14 pages, 425 KB  
Article
Diagnostic Efficiency of Endometrial Sampling Methods and Risk Factors for Endometrial Carcinoma and Precursor Lesions in Premenopausal Women
by Firdevs Öztürk, Saliha Sağnıç, Serap Fırtına Tuncer and Hasan Aykut Tuncer
J. Clin. Med. 2025, 14(11), 3658; https://doi.org/10.3390/jcm14113658 - 23 May 2025
Viewed by 1645
Abstract
Objective: Accurate preoperative differentiation between benign endometrial conditions and malignancies is essential for guiding therapeutic interventions. However, high-quality evidence regarding the diagnostic accuracy of endometrial sampling techniques remains insufficient. This study aimed to evaluate the diagnostic efficiency of hysteroscopically directed biopsy, Pipelle suction [...] Read more.
Objective: Accurate preoperative differentiation between benign endometrial conditions and malignancies is essential for guiding therapeutic interventions. However, high-quality evidence regarding the diagnostic accuracy of endometrial sampling techniques remains insufficient. This study aimed to evaluate the diagnostic efficiency of hysteroscopically directed biopsy, Pipelle suction curettage, and dilatation and curettage (D&C) for detecting endometrial hyperplasia or carcinoma in premenopausal women and to identify associated risk factors. Methods: A retrospective single-center cohort analysis was conducted on 2054 premenopausal women. Demographic, clinical, and obstetric data, along with biopsy techniques and histopathological findings, were recorded. Diagnostic accuracy of biopsy methods was compared against definitive surgical pathology. Results: The prevalence of endometrial hyperplasia and carcinoma was 5.6% and 1.0%, respectively. Hysteroscopically directed biopsy demonstrated superior diagnostic accuracy (AUC 0.957) compared to D&C (AUC 0.909) and Pipelle suction curettage (AUC 0.858). Sensitivity was highest for hysteroscopically directed biopsy (91.3%), followed by D&C (82.0%) and Pipelle suction curettage (71.7%), while specificity remained excellent across all methods (p < 0.001). Elevated BMI increased the risk of hyperplasia or carcinoma by 1.05 times per unit increase (OR = 1.054, p = 0.005), while hypertension nearly doubled the risk (OR = 1.99, p = 0.009). Multiparity showed protective effects, reducing risk with each additional delivery (OR = 0.877, p = 0.029). Conclusions: Hysteroscopically directed biopsy provides superior diagnostic accuracy for detecting endometrial hyperplasia and carcinoma in premenopausal women. Hypertension and elevated BMI increase risk, while multiparity offers protective benefits. Full article
(This article belongs to the Section Obstetrics & Gynecology)
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26 pages, 2630 KB  
Review
Endermologie as a Complementary Therapy in Medicine and Surgery and an Effective Aesthetic Procedure: A Literature Review
by Anna Kołodziejczak, Julia Adamiak and Helena Rotsztejn
Appl. Sci. 2025, 15(8), 4313; https://doi.org/10.3390/app15084313 - 14 Apr 2025
Viewed by 7189
Abstract
Endermologie is a non-invasive mechanical massage technique that combines suction, mechanized rollers and/or flaps, and mechanotransduction principles to stimulate the skin and subcutaneous tissues. This review assessed endermologie’s therapeutic indications and physiological effects. A comprehensive literature search was conducted using EDS DB (Med [...] Read more.
Endermologie is a non-invasive mechanical massage technique that combines suction, mechanized rollers and/or flaps, and mechanotransduction principles to stimulate the skin and subcutaneous tissues. This review assessed endermologie’s therapeutic indications and physiological effects. A comprehensive literature search was conducted using EDS DB (Med Univ) and PubMed to identify relevant studies published between 2000 and February 2025. Two authors independently screened studies, resulting in 24 articles included in the qualitative synthesis. Key applications identified included for burns, scars, muscle regeneration, lymphedema, cellulite, panniculitis/lipoatrophy, skin elasticity improvement, fat reduction, morphea, fibromyalgia, pre- and post-liposuction care, peri-oncology rehabilitation, orthopedics, and postoperative recovery. Research highlights the importance of treatment frequency, duration, and mechanostimulation parameters in determining therapeutic outcomes. Studies indicate that endermologie induces extracellular matrix remodeling, fibroblast activation, adipocyte fat release sensitivity, and enhanced venolymphatic circulation. Documented effects include improved microcirculation, anti-fibrotic properties, enhanced skin elasticity, fluid drainage, and pain relief, contributing to scar management, tissue softening, and post-surgical rehabilitation. Despite its potential, methodological heterogeneity across studies limits direct comparability, emphasizing the need for future research on standardization and long-term efficacy validation. Full article
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9 pages, 741 KB  
Brief Report
Effectiveness of Subcutaneous Negative-Suction Drain on Surgical Site Infection After Ileostomy Reversal: A Propensity Score Matching Analysis
by Ju Myung Song, Ji Hoon Kim, Moon Jin Kim, Chae Dong Lim and Yoon Suk Lee
J. Clin. Med. 2025, 14(1), 236; https://doi.org/10.3390/jcm14010236 - 3 Jan 2025
Viewed by 1003
Abstract
Background/Objective: Surgical site infection (SSI) is a leading common condition after ileostomy reversal (IR). However, evidence is unclear that subcutaneous negative-suction drainage (SND) reduces the incidence of SSI. This study aimed to investigate whether SND effectively reduced the incidence of SSI. Methods: We [...] Read more.
Background/Objective: Surgical site infection (SSI) is a leading common condition after ileostomy reversal (IR). However, evidence is unclear that subcutaneous negative-suction drainage (SND) reduces the incidence of SSI. This study aimed to investigate whether SND effectively reduced the incidence of SSI. Methods: We retrospectively analyzed the records of 531 patients who underwent IR at Incheon St. Mary’s Hospital between June 2005 and December 2020. SND was classified into two groups based on its presence or absence. The estimated risk of SSI was calculated using the surgical risk calculator of the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP). After 1:1 propensity score matching (PSM) using the estimated risk of SSI, we analyzed the two group’s postoperative outcomes, including SSI rates. Results: After PSM, there was no difference in demographics between the two groups; however, the reversal interval was longer in the SND group than in the no SND group (193.3 ± 151.6 vs. 151.5 ± 141.0 days, p = 0.005). The incidence of SSI was lower in the SND group than in the no SND group (5.2% vs. 13.0%, p = 0.013). Conclusions: SND insertion can reduce the incidence of SSI during IR. Therefore, SND insertion should be considered as a basic technique for reducing SSI after IR. Full article
(This article belongs to the Special Issue Advances in the Colorectal Cancer)
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17 pages, 1531 KB  
Review
Sternal Wound Reconstruction Following Deep Sternal Wound Infection: Past, Present and Future: A Literature Review
by Arwa Khashkhusha, Sundas Butt, Mariam Abdelghaffar, William Wang, Asveny Rajananthanan, Sakshi Roy, Bakht Noor Khurshid, Mohamed Zeinah and Amer Harky
J. Cardiovasc. Dev. Dis. 2024, 11(11), 361; https://doi.org/10.3390/jcdd11110361 - 7 Nov 2024
Cited by 2 | Viewed by 2598
Abstract
This literature review critically examines the historical, current, and prospective dimensions of sternal wound reconstruction in the specific context of deep sternal wound infection (DSWI), aiming to enhance patient outcomes and optimise surgical techniques. Preventive measures, including prophylactic antibiotic administration and surgical site [...] Read more.
This literature review critically examines the historical, current, and prospective dimensions of sternal wound reconstruction in the specific context of deep sternal wound infection (DSWI), aiming to enhance patient outcomes and optimise surgical techniques. Preventive measures, including prophylactic antibiotic administration and surgical site preparation, are crucial in reducing the incidence of DSWI. Effective management necessitates a multidisciplinary approach encompassing surgical debridement, drainage, and sternum repair utilising diverse procedures in conjunction with antibiotic therapy. Traditional approaches to managing DSWI involved closed irrigation and drainage techniques. While these methods exhibited certain advantages, they also exhibited limitations and varying degrees of success. The current care paradigms emphasise prophylactic antibiotic administration and surgical interventions like closed suction and irrigation, vacuum-assisted closure, and flap reconstruction. Future advancements in surgical techniques and technology hold promise for further enhancing sternal wound reconstruction. This review separates and emphasises the distinct roles of prophylaxis, antibiotic treatment, and reconstructive techniques, each relevant specifically to DSWI management. Collaborative efforts between cardiac and plastic surgeons, supported by ongoing research and innovation, are indispensable to advance sternal wound restoration and achieve superior outcomes in terms of patient welfare, morbidity and mortality reduction, and surgical efficacy. Full article
(This article belongs to the Special Issue Risk Factors and Outcomes in Cardiac Surgery)
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16 pages, 2850 KB  
Review
The Current State of Lymphedema Surgery
by Erin N. McGinity, William F. Bray and Jay W. Granzow
Lymphatics 2024, 2(4), 212-227; https://doi.org/10.3390/lymphatics2040017 - 21 Oct 2024
Cited by 2 | Viewed by 7125
Abstract
Lymphedema surgeries have been proven effective in treating lymphedema and are not considered experimental or unproven. The medical literature consistently supports the safe and successful use of physiologic drainage lymphedema surgeries such as lymphaticovenous anastomosis (LVA), vascularized lymph node transfer (VLNT), and reductive [...] Read more.
Lymphedema surgeries have been proven effective in treating lymphedema and are not considered experimental or unproven. The medical literature consistently supports the safe and successful use of physiologic drainage lymphedema surgeries such as lymphaticovenous anastomosis (LVA), vascularized lymph node transfer (VLNT), and reductive surgeries such as suction-assisted protein lipectomy (SAPL) when performed by an experienced lymphedema surgery team to treat properly selected patients. Proper integration of lymphedema therapy is critical to achieving successful outcomes. We review effective lymphedema surgeries, their indications, patient selection, and the proper application of surgical treatments to achieve optimal results. Full article
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12 pages, 8185 KB  
Case Report
Surgical Drainage and Simultaneous Sinus Floor Augmentation in Patients with Chronic Maxillary Sinusitis
by Won-Bae Park, Hye-Kyoung Seol, Seungil Shin and Ji-Youn Hong
Medicina 2024, 60(8), 1256; https://doi.org/10.3390/medicina60081256 - 2 Aug 2024
Cited by 1 | Viewed by 2750
Abstract
Chronic maxillary sinusitis accompanied by severe thickening of the sinus mucosa, blockage of the ostium, and patient-reported symptoms requires preoperative assessment and treatment by an otolaryngologist before maxillary sinus floor augmentation (MSFA). Prescription of antibiotics and nasal saline irrigation are the first choice [...] Read more.
Chronic maxillary sinusitis accompanied by severe thickening of the sinus mucosa, blockage of the ostium, and patient-reported symptoms requires preoperative assessment and treatment by an otolaryngologist before maxillary sinus floor augmentation (MSFA). Prescription of antibiotics and nasal saline irrigation are the first choice of treatment; however, endoscopic sinus surgery is considered when the treatment’s effect is limited and drug resistance is observed. Nevertheless, MSFA performed in the presence of sinus pathologies have been reported to have favorable results when the lesions are managed properly. This report presents cases of two patients who required MSFA but were diagnosed with chronic maxillary sinusitis (case 1 with nasal sinusitis and case 2 with dental sinusitis). After 2 weeks of antibiotic therapy, endoscopic surgery was recommended due to minimal changes in the size of the sinus lesion; however, the patients refused because of improved self-reported symptoms. Therefore, intraoral surgical drainage was planned as an alternative treatment. A large bony window was prepared at the lateral wall of the maxillary sinus, and a long intentional incision was made to improve access for the suction tip in various directions and depths into the sinus cavity. Thorough suction of the purulent exudate and saline irrigation were performed through this access. The size of the perforated area was reduced along with the elevation of the Schneiderian membrane from the sinus floor, and simultaneous bone grafting with implant placement was performed. Prosthesis was delivered after 6–8 months. At 1-year follow-up after loading, favorable outcomes of implant survival and maintenance of augmented bone height were observed, with no recurrence of postoperative sinusitis. Within the limitations of the present case report, thorough sinus drainage and saline irrigation during maxillary sinus floor augmentation resolved sinus infection in patients with chronic maxillary sinusitis with short-term clinical outcomes. Full article
(This article belongs to the Special Issue Recent Advances in Periodontics and Dental Implantology: Part II)
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18 pages, 3763 KB  
Systematic Review
Similar Short-Term Outcomes of Adolescent Idiopathic Scoliosis Surgery with or without Drainage: A Systematic Review of the Literature and Meta-Analysis
by Alberto Ruffilli, Matteo Traversari, Giovanni Viroli, Marco Manzetti, Marco Ialuna, Manuele Morandi Guaitoli, Antonio Mazzotti, Elena Artioli, Simone Ottavio Zielli, Alberto Arceri and Cesare Faldini
J. Pers. Med. 2024, 14(4), 339; https://doi.org/10.3390/jpm14040339 - 24 Mar 2024
Viewed by 1893
Abstract
The use of closed suction drains post posterior spinal fusion for adolescent idiopathic scoliosis (AIS) is common practice, although evidence on its impact is limited compared to that for knee and hip arthroplasty. This study aimed to assess the effect of closed suction [...] Read more.
The use of closed suction drains post posterior spinal fusion for adolescent idiopathic scoliosis (AIS) is common practice, although evidence on its impact is limited compared to that for knee and hip arthroplasty. This study aimed to assess the effect of closed suction drainage on short-term post-operative outcomes in AIS surgery. A systematic review following PRISMA guidelines was conducted, including studies comparing outcomes with and without drainage. Data on blood loss, transfusions, hospital stay, and complications were collected and subjected to meta-analysis. Five studies involving 772 patients were analyzed. The meta-analysis found no significant difference in blood transfusion rates (p = 0.107) or hospital stay (p = 0.457) between groups. Complications, including surgical site infections, were more common without drainage, though not statistically significant (p = 0.356). Reintervention rates were higher in the no-drainage group, but not significantly (p = 0.260). Overall, this review found no significant short-term outcome differences, suggesting clinical judgment should guide drainage decisions. Further research, particularly with enhanced recovery protocols, is warranted to clarify drainage’s role in AIS surgery. Full article
(This article belongs to the Special Issue New Concepts in Musculoskeletal Medicine)
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9 pages, 1055 KB  
Article
Efficacy of Filter Trocar for Clear Visualization during Laparoscopic Cholecystectomy: A Prospective Randomized Controlled Trial
by Ho-Chang Chae, Beom-Jin Kim, Yoo Shin Choi, Suk-Won Suh and Seung Eun Lee
J. Pers. Med. 2024, 14(2), 204; https://doi.org/10.3390/jpm14020204 - 13 Feb 2024
Cited by 1 | Viewed by 1926
Abstract
Filter trocar designed to eliminate harmful smoke is also regarded as effective for improving surgical visualization. The aim of this study is to evaluate the efficacy of filter trocar in maintaining clear operative view. From 2019 to 2020, 100 patients underwent laparoscopic cholecystectomy [...] Read more.
Filter trocar designed to eliminate harmful smoke is also regarded as effective for improving surgical visualization. The aim of this study is to evaluate the efficacy of filter trocar in maintaining clear operative view. From 2019 to 2020, 100 patients underwent laparoscopic cholecystectomy and they were randomized to either the control or filter group. The primary end point was a laparoscopic operative view score (1, clear; 2, slightly blurry; 3, completely blurry) during gallbladder dissection from the liver bed when dissection was started (LV1), when dissection was half completed (LV2) and when dissection was completed (LV3). Between the control and filter groups, there were no significant differences in mean LV1 (1.44 vs. 1.40, p = 0.234) and LV3 (1.86 vs. 2.01, p = 0.880). There was no significant difference in the mean duration of suction after dissection (3.82 s vs. 3.67 s, p = 0.097) and the mean number of laparoscope removals from inside to outside the body to clean during gallbladder dissection from the liver bed (0.55 vs. 0.22, p = 0.963) or the mean amount of time required to dissect the gallbladder from the liver bed (221.58 s vs. 177.09 s, p = 0.253). The study demonstrated that filter trocar is not as effective as expected in the maintenance of clear operative view. Further study is needed to develop devices to improve clear surgical visualization. Full article
(This article belongs to the Section Methodology, Drug and Device Discovery)
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10 pages, 225 KB  
Review
Intraoperative Extracorporeal Support during Lung Transplantation: Not Just for the High-Risk Patient
by Daniel Laskey, Brian Housman, Gbalekan Dawodu and Scott Scheinin
J. Clin. Med. 2024, 13(1), 192; https://doi.org/10.3390/jcm13010192 - 29 Dec 2023
Cited by 9 | Viewed by 2007
Abstract
The use of intraoperative mechanical support during lung transplantation has traditionally been a controversial topic. Trends for intraoperative mechanical support strategies swing like a pendulum. Historically, cardiopulmonary bypass (CPB) was the modality of choice during transplantation. It provides full hemodynamic support including oxygenation [...] Read more.
The use of intraoperative mechanical support during lung transplantation has traditionally been a controversial topic. Trends for intraoperative mechanical support strategies swing like a pendulum. Historically, cardiopulmonary bypass (CPB) was the modality of choice during transplantation. It provides full hemodynamic support including oxygenation and decarboxylation. Surgical exposure is improved by permitting the drainage of the heart and provides more permissive retraction. CPBs contain drainage reservoirs with hand-held pump suction catheters promoting blood conservation through collection and re-circulation. But CPB has its disadvantages. It is known to cause systemic inflammation and coagulopathy. CPB requires high doses of heparinization, which increases bleeding risks. As transplantation progressed, off-pump transplantation began to trend as a preferable option. ECMO, however, has many of the benefits of CPB with less of the risk. Outcomes were improved with ECMO compared to CPB. CPB has a higher blood transfusion requirement, a higher need for post-operative ECMO support, a higher re-intubation rate, high rates of kidney injury and need for hemodialysis, longer ICU stays, higher incidences of PGD grade 3, as well as overall in-hospital mortality when compared with ECMO use. The focus now shifts to using intraoperative mechanical support to protect the graft, helping to reduce ischemia-reperfusion injury and allowing for lung protective ventilator settings. Studies show that the routine use of ECMO during transplantation decreases the rate of primary graft dysfunction and many adverse outcomes including ventilator time, need for tracheostomy, renal failure, post-operative ECMO requirements, and others. As intraoperative planned ECMO is considered a safe and effective approach, with improved survival and better overall outcomes compared to both unplanned ECMO implementation and off-pump transplantation, its routine use should be taken into consideration as standard protocol. Full article
(This article belongs to the Section Respiratory Medicine)
21 pages, 31606 KB  
Article
Surgical Site-Released Tissue Is Potent to Generate Bone onto TCP and PCL-TCP Scaffolds In Vitro
by Emely Rehage, Andrea Sowislok, André Busch, Eleftherios Papaeleftheriou, Melissa Jansen and Marcus Jäger
Int. J. Mol. Sci. 2023, 24(21), 15877; https://doi.org/10.3390/ijms242115877 - 1 Nov 2023
Cited by 3 | Viewed by 2147
Abstract
There is evidence that surgical site tissue (SSRT) released during orthopedic surgery has a strong mesenchymal regenerative potential. Some data also suggest that this tissue may activate synthetic or natural bone substitute materials and can thus upgrade its osteopromoting properties. In this comparative [...] Read more.
There is evidence that surgical site tissue (SSRT) released during orthopedic surgery has a strong mesenchymal regenerative potential. Some data also suggest that this tissue may activate synthetic or natural bone substitute materials and can thus upgrade its osteopromoting properties. In this comparative in vitro study, we investigate the composition of SSRT during total hip replacement (n = 20) harvested using a surgical suction handle. In addition, the osteopromoting effect of the cells isolated from SSRT is elucidated when incubated with porous beta-tricalcium phosphate (β-TCP) or 80% medical-grade poly-ε-caprolactone (PCL)/20% TCP composite material. We identified multiple growth factors and cytokines with significantly higher levels of PDGF and VEGF in SSRT compared to peripheral blood. The overall number of MSC was 0.09 ± 0.12‰ per gram of SSRT. A three-lineage specific differentiation was possible in all cases. PCL-TCP cultures showed a higher cell density and cell viability compared to TCP after 6 weeks in vitro. Moreover, PCL-TCP cultures showed a higher osteocalcin expression but no significant differences in osteopontin and collagen I synthesis. We could demonstrate the high regenerative potential from SSRT harvested under vacuum in a PMMA filter device. The in vitro data suggest advantages in cytocompatibility for the PCL-TCP composite compared to TCP alone. Full article
(This article belongs to the Special Issue Advances in Biomaterials for Hard and Soft Tissue Engineering)
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13 pages, 1046 KB  
Article
Minimalized Erlangen Correction Method by Hümmer (MEK) Compared with Conventional and Minimally Invasive Correction Methods for Pectus Excavatum Single Center Experience
by Markus Denzinger, Patricia Reis Wolfertstetter, Daniel Sossau, Hans Peter Hümmer and Christian Knorr
Appl. Sci. 2023, 13(18), 10009; https://doi.org/10.3390/app131810009 - 5 Sep 2023
Cited by 1 | Viewed by 2480
Abstract
Pectus excavatum (funnel chest) is the most common chest wall deformity in childhood and adolescence with a prevalence in the literature ranging from 1 in 3400 to 1 in 1000. In addition to conservative therapy with a suction cup and physiotherapy to improve [...] Read more.
Pectus excavatum (funnel chest) is the most common chest wall deformity in childhood and adolescence with a prevalence in the literature ranging from 1 in 3400 to 1 in 1000. In addition to conservative therapy with a suction cup and physiotherapy to improve posture, fitness, and muscle strength, there are several different surgical techniques, many of which have been improved over time. In evaluating the Minimalized Erlangen Correction Method (MEK), the main purpose of this retrospective analysis is to present the results and to compare them with reports on the Minimally Invasive Repair of Pectus Excavatum (MIRPE) technique, especially regarding long-term patient satisfaction, and with other open surgical methods in terms of operative trauma, as well as flexibility in its application, risk of complications, and patient safety. Full article
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10 pages, 2375 KB  
Article
Rectal Biopsy for Hirschsprung’s Disease: A Multicentre Study Involving Biopsy Technique, Pathology and Complications
by Gil Vervloet, Antoine De Backer, Stijn Heyman, Paul Leyman, Sebastiaan Van Cauwenberge, Kim Vanderlinden, Charlotte Vercauteren, Dirk Vervloessem and Marc Miserez
Children 2023, 10(9), 1488; https://doi.org/10.3390/children10091488 - 31 Aug 2023
Cited by 7 | Viewed by 4239
Abstract
Background: The heterogeneity of rectal biopsy techniques has encouraged us to search for a surgical and pathological standardisation of this diagnostic technique to exclude Hirschsprung’s disease. The different amounts of information on the anatomopathology report prompted us to compile a template for the [...] Read more.
Background: The heterogeneity of rectal biopsy techniques has encouraged us to search for a surgical and pathological standardisation of this diagnostic technique to exclude Hirschsprung’s disease. The different amounts of information on the anatomopathology report prompted us to compile a template for the anatomopathology report for diagnostic rectal biopsies for surgical colleagues and pathologists working on Hirschsprung’s disease. Methods: We gathered the anonymous biopsy information and its pathology information from five hospitals for all patients in which rectal biopsies were taken to diagnose Hirschsprung’s disease over two years (2020–2021). Results: Of the 82 biopsies, 20 suction (24.4%), 31 punch (37.8%) and 31 open biopsies (37.8%) were taken. Of all biopsies, 69 were conclusive (84.2%), 13 were not (15.8%). In the suction biopsy group, 60% were conclusive and 40% were not; for punch biopsy, the values were 87% and 13%, respectively and for open biopsy, 97% and 3%. Inconclusive results were due to insufficient submucosa in 6/8 suction biopsies, 4/4 punch biopsies and 0/1 open biopsies. An insufficient amount of submucosa was the reason for an inconclusive result in 6/20 cases (30%) after suction biopsy, 4/31 (12.9%) cases after punch biopsy and 0 cases (0%) after open biopsy. We had one case with major postoperative bleeding post suction biopsy; there were no further adverse effects after biopsy. Conclusions: Diagnostic rectal biopsies in children are safe. Non-surgical biopsies are more likely to give inconclusive results due to smaller amounts of submucosa present in the specimen. Open biopsies are especially useful when previous non-surgical biopsies are inconclusive. An experienced pathologist is a key factor for the result. The anatomopathology report should specify the different layers present in the specimen, the presence of ganglion cells and hypertrophic nerve fibres, their description and a conclusion. Full article
(This article belongs to the Special Issue Advances in Gastrointestinal Surgery in Children)
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11 pages, 1265 KB  
Article
Efficacy of Continuous Suctioning in Adenoidectomy Haemostasis—Clinical Study
by Veronica Epure, Razvan Hainarosie and Dan Cristian Gheorghe
Medicina 2023, 59(9), 1534; https://doi.org/10.3390/medicina59091534 - 24 Aug 2023
Viewed by 1573
Abstract
Introduction: Adenoidectomy is often the first major surgical challenge for the child’s haemostatic system, and controlling intraoperative bleeding can be a challenge for the surgeon. Different methods have been used intraoperatively by surgeons in order to enhance haemostasis. The cold air effect [...] Read more.
Introduction: Adenoidectomy is often the first major surgical challenge for the child’s haemostatic system, and controlling intraoperative bleeding can be a challenge for the surgeon. Different methods have been used intraoperatively by surgeons in order to enhance haemostasis. The cold air effect (continuous suctioning) has been used by some surgeons during adenoidectomy; however, no documentation of its haemostatic effect has been made. Objectives: Our prospective randomised controlled study enrolled a sample of 140 children undergoing adenoidectomy, and we studied the effect of continuous suctioning on the duration of haemostasis in paediatric adenoidectomy. Materials and Methods: We evaluated the effect of using continuous suctioning during haemostasis at the end of adenoidectomy procedures, comparing variables such as total surgery time, total haemostasis time, and intraoperative blood loss, between two groups: 70 adenoidectomy procedures where no continuous suctioning was used to enhance haemostasis versus the other 70 patients where continuous suctioning was the haemostatic method employed. RESULTS: After statistical analysis of the recorded data, we found that the total duration of adenoidectomy, the duration of haemostasis in adenoidectomy, and the intraoperative blood loss were significantly lower in patients in whom cold air was used for haemostasis. Intraoperative haemostasis failure (and consequent use of electrocautery for haemostasis) was more frequent in patients in whom no suctioning was used; as for the rates of postoperative primary bleeding after adenoidectomy, they were similar in both groups of patients, regardless of the technique used for haemostasis. Conclusions: The use of continuous suctioning during adenoidectomy haemostasis significantly shortens total surgical and haemostasis time, reduces intraoperative blood loss, and reduces the incidence of haemostasis failure (with the consequent need for bipolar electrocautery haemostasis). Full article
(This article belongs to the Special Issue Current Trends in Otorhinolaryngology and Head and Neck Pathology)
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