Search Results (1,124)

Objective: The prevalence and severity of obstructive sleep apnea (OSA) increase with age, suggesting that age-related factors are etiological factors for OSA in older adults. In addition to anatomic contractions of the upper respiratory tract, such as those caused by obesity and retrognathia, sleep is impaired in older OSA patients due to aging. Although aging has long been associated with structural changes in the upper airway potential, specific age-related anatomical differences in patients with OSA are not established. This study aimed to examine age-related morphological differences in OSA patients, particularly in older adults. Methods: This study was designed as a retrospective cross-sectional study conducted at the Center for Dental Sleep Medicine, Osaka Dental University, between May 2017 and September 2022. From an initial cohort of 1032 patients, 183 male participants were included after applying strict inclusion and exclusion criteria. Patients were classified into two age groups: middle age (40–60 years) and older age (≥65 years). Polysomnographic parameters; body mass index (BMI); airway space (AS) obtained from cephalometric radiographs; length of the soft palate (PNS-P); SNB angle, as an indicator of mandibular position; and the position of the hyoid bone (MP-H) were compared between the groups. Statistical analysis included Levene’s test for homogeneity of variances, independent sample t-tests for group comparisons, and multiple regression analyses to identify independent predictors of AHI. This study was conducted with the approval of the Ethics Committee of Osaka Dental University (No. 111047). Results: Older patients showed significantly lower REM sleep percentage (13.5 ± 1.31% vs. 16.4 ± 0.59%, p = 0.047), significantly lower BMI (23.6 ± 0.45 kg/m² vs. 24.6 ± 0.29 kg/m², p = 0.049), and significantly larger AS (15.8 ± 0.52 mm vs. 12.0 ± 0.27 mm, p = 0.000) compared to middle-aged patients. Furthermore, in the middle-aged group, BMI (β = 0.40, 95% CI: 1.46 to 3.41, p < 0.001), SNB (β = −0.18, 95% CI: −1.75 to −0.09, p = 0.030), and MP-H (β = 0.19, 95% CI: 0.10 to 1.01, p = 0.018) were significant independent predictors of AHI. In the older group, no parameters were significant predictors of AHI. Conclusions: We found that older adult patients had a larger airway diameter and lower REM sleep percentage and BMI than middle-aged patients. Furthermore, regarding factors associated with AHI, which is an indicator of sleep apnea severity, in the middle-aged group, anatomical factors such as BMI, SNA, and MPH contributed significantly, but in the older adult group, anatomical factors were not relevant. The results suggested that anatomical factors alone may not fully explain the pathogenesis of OSA in older patients, highlighting the need for further studies focusing on other age-related factors. Full article

The real nature of little red dots (LRDs), a class of very compact galaxies in the early Universe recently discovered by the James Webb Space Telescope, is still poorly understood. The most popular theories competing to interpret the phenomena include active galactic nuclei and enhanced star formation in dusty galaxies. To date, however, neither model gives a completely satisfactory explanation to the population as a whole; thus, alternative theories have arisen, including tidal disruption events (TDEs). By considering observational constraints on the radio emission of LRDs, we discuss whether TDEs are adequate alternatives solving these high-redshift enigmas. We utilise radio flux density upper limits from LRD stacking analyses, TDE peak radio luminosities, and volumetric density estimates. We find that the characteristic values of flux densities and luminosities allow radio-quiet TDEs as the underlying process of LRDs in any case, while the less common radio-loud TDEs are compatible with the model under special constraints only. Considering other factors, such as volumetric density estimates, delayed and long-term radio flares of TDEs, and cosmological time dilation, TDEs appear to be a plausible explanation for LRDs from the radio point of view. Full article

The coupling of quantum computing with multi-agent reinforcement learning (MARL) provides an exciting direction to tackle intricate decision-making tasks in high-dimensional spaces. This work introduces a new quantum-inspired multi-agent reinforcement learning (QiMARL) model, utilizing quantum parallelism to achieve learning efficiency and scalability improvement. The QiMARL model is tested on an energy distribution task, which optimizes power distribution between generating and demanding nodal power stations. We compare the convergence time, reward performance, and scalability of QiMARL with traditional Multi-Armed Bandit (MAB) and Multi-Agent Reinforcement Learning methods, such as Greedy, Upper Confidence Bound (UCB), Thompson Sampling, MADDPG, QMIX, and PPO methods with a comprehensive ablation study. Our findings show that QiMARL yields better performance in high-dimensional systems, decreasing the number of training epochs needed for convergence while enhancing overall reward maximization. We also compare the algorithm’s computational complexity, indicating that QiMARL is more scalable to high-dimensional quantum environments. This research opens the door to future studies of quantum-enhanced reinforcement learning (RL) with potential applications to energy optimization, traffic management, and other multi-agent coordination problems. Full article

This study explores the critical role of the flow deflector in suppressing boundary layer separation and enhancing aerodynamic efficiency through systematic geometric parameterization and computational analysis. By defining eight key design variables, this research identifies optimal configurations that significantly delay flow separation at high angles of attack. Computational Fluid Dynamics (CFD) simulations reveal that optimized deflector geometries enhance suction peaks near the airfoil leading edge, redirect separated flow toward the upper surface, and inject momentum into the boundary layer to generate a more positive lift coefficient. The numerical results demonstrate that the optimized design achieves a 58.4% increase in lift coefficient and an 83.3% improvement in the lift–drag ratio by effectively mitigating large-scale vortical structures inherent in baseline configurations. Sensitivity analyses further highlight threshold-dependent “sudden-jump” behaviors in lift coefficients for parameters such as element spacing and deflection angles, while thickness exhibits minimal influence. Additionally, pre-stall optimizations show that strategically aligned deflectors preserve baseline performance with a 0.4% lift gain, whereas misaligned configurations degrade aerodynamic efficiency by up to 9.1%. These findings establish a direct correlation between deflector-induced flow redirection and separation suppression, offering actionable insights for passive flow control in stalled regimes. This research advances fundamental understanding of flow deflector-based separation management and provides practical guidelines for enhancing aerodynamic performance in aerospace applications. Full article

Interferometric signals in space-borne Gravitational Wave Detectors are measured by digital phasemeters. The phasemeter processes signals generated by multiple interferometers, with its primary function being micro-radian level phase measurements. The Science Interferometer is responsible for inter-spacecraft measurements, including relative ranging, absolute ranging, laser communication, and clock noise transfer. Since the scientific interferometer incorporates multiple functions and various signals are simultaneously coupled into the heterodyne signal, establishing a suitable evaluation environment is a crucial foundation for achieving micro-radian level phase measurement during ground testing and verification. This paper evaluates the phase measurement noise of the science interferometer by simulating the heterodyne signal and establishing a test environment. The experimental results show that when the simulated heterodyne signal contains the main beat-note, upper and lower sideband beat-notes, and PRN modulation simultaneously, the phase measurement noise of the main beat-note, upper and lower sideband beat-notes all reach 2π μrad/Hz^1/2@(0.1 mHz–1 Hz), meeting the requirements of the space gravitational wave detection mission. An experimental verification platform and performance reference benchmark have been established for subsequent research on the impact of specific noise on phase measurement performance and noise suppression methods. Full article

To address the issue of cracking damage under extreme high-temperature rutting, which is not sufficiently considered in the selection of preventive maintenance programs, the objective of this study was to investigate the preventive maintenance-oriented minor internal damage changes in asphalt concrete with a normal maximum aggregate size of 16 mm (AC-16) under extreme high temperature (70 °C) and load (1.4 MPa) conditions. The changes in void structure within the 0–10 mm rutting depth were tracked through the rutting test and Computer Tomography (CT) image analysis. It was observed that there were notable discrepancies in the three-dimensional (3D) space distribution of void, void volume development, and void morphology between the rut impact zones and the rutted part. The impact zone exhibited a greater prevalence of voids and an earlier onset of cracking. At a rutting depth of only 5 mm, multiple top-down developed cracks (TDCs) of over 6 mm length were observed in the impact zone. At a rutting depth of 10 mm, the TDCs in the impact zone were more numerous, larger, and wider, indicating the necessity for a tailored repair program that includes milling. TDC damage caused by high-temperature rutting is predominantly observed in the upper and middle positions of the height direction, with the bottom position data exhibiting greater inconsistency due to the influence of molding. Furthermore, the combination of void morphology indicators with void volume can effectively track the occurrence and development of microcracks. However, the fine-scale assessment of compaction degree and deformation process using the equivalent void diameter indicator is not sufficiently differentiated. Full article

We propose a novel method for controlling the frequency of semiconductor lasers. This technique facilitates the production of devices with fast frequency tuning and intrinsic linearization of laser frequency sweeps. The electrical contact layer positioned between the lower undoped cladding and the waveguide, along with the upper laser contact, is used for the optical gain pumping. Since the laser pumping current does not pass through the lower cladding, changes in carrier concentration within the cladding affect the laser frequency while minimally impacting the device’s output power. Control of the free carrier concentration in the lower cladding is achieved using the space-charge-limited current (SCLC) technique. This novel approach establishes a linear relationship between the laser frequency shift (∆f) and voltage (V) applied to the cladding—an essential feature for light detection and ranging (LIDAR) system development. The proposed technique is applicable to all semiconductor lasers. As an example, we present the calculated characteristics of a quantum cascade laser (QCL) operating at a 10 µm wavelength. Full article

A novel dual-band dual-mode wearable button antenna for wireless body area network (WBAN) applications is proposed in this paper. The antenna ingeniously integrates a monopole structure and an optimized planar inverted-F antenna (PIFA) configuration in a shared radiator, enabling dual-mode operation with a compact size. In the low-frequency band, the monopole structure generates an omnidirectional radiation pattern, facilitating efficient on-body communication. Meanwhile, the PIFA structure in the high-frequency band exhibits directed radiation, optimizing off-body communication. To enhance bandwidth, a parasitic structure is incorporated into the design. Both numerical simulations and experimental measurements are conducted to evaluate the antenna’s bandwidth and radiation performance in free space and on-body environments, with results showing excellent agreement. The measured bandwidth of the antenna on the human tissue is 300 MHz (2.3–2.6 GHz) in the low-frequency band and 4.5 GHz (5.5–10 GHz) in the high-frequency band. The maximum radiation efficiency reaches 76% in the low band (2.4–2.4835 GHz) and 93% in the upper band (5.725–5.875 GHz). Additionally, the peak gain on the human body can achieve 2.5 dB and 6.9 dB for the low and upper bands, respectively. The results confirm that the antenna meets the design requirements for Industrial, Scientific, and Medical (ISM) band applications, making it a promising candidate for WBAN systems. Full article

The often used analytical representation of the Maxwell–Boltzmann classical speed distribution function (F) for elastic, indivisible particles assumes an infinite limit for the speed. Consequently, volume and the number of particles (n) extend to infinity: Both infinities contradict assumptions underlying this non-relativistic formulation. Finite average kinetic energy and temperature (T) result from normalization of F removing n: However, total energy (i.e., heat of the collection) remains infinite because n is infinite. This problem persists in recent adaptations. To better address real (finite) systems, wherein T depends on heat, we generalize this one-parameter distribution (F, cast in energy) by proposing a two-parameter gamma distribution function (F*) in energy which reduces to F at large n. Its expectation value of kT (k = Boltzmann’s constant) replicates F, whereas the shape factor depends on n and affects the averages, as expected for finite systems. We validate F* via a first-principle, molecular dynamics numerical model of energy and momentum conserving collisions for 26, 182, and 728 particles in three-dimensional physical space. Dimensionless calculations provide generally applicable results; a total of 10⁷ collisions suffice to represent an equilibrated collection. Our numerical results show that individual momentum conserving collisions in three-dimensions provide symmetrical speed distributions in all Cartesian directions. Thus, momentum and energy conserving collisions are the physical cause for equipartitioning of energy: Validity of this theorem for other systems depends on their specific motions. Our numerical results set upper limits on kinetic energy of individual particles; restrict the n particles to some finite volume; and lead to a formula in terms of n for conserving total energy when utilizing F* for convenience. Implications of our findings on matter under extreme conditions are briefly discussed. Full article

Accurate path-loss characterization in the upper mid-band is critical for 5G/6G outdoor planning, yet classical deterministic expressions lose fidelity at 18 GHz, and purely data-driven regressors offer limited physical insight. We present a physics-guided residual learner that couples a calibrated two-ray model with an XGBoost regressor trained on the deterministic residuals. To enlarge the feature space without promoting overfitting, synthetic samples obtained by perturbing antenna height and ground permittivity within realistic bounds are introduced with a weight of $w=0.3$. The methodology is validated with narrowband measurements collected along two straight 25 m corridors. Under cross-corridor transfer, the hybrid predictor attains $0.59$–$0.62$ dB RMSE and $R^2\ge 0.996$, reducing the error of a pure-ML baseline by half and surpassing deterministic formulas by a factor of four. Small-scale analysis yields decorrelation lengths of 0.23 m and 0.41 m; a cross-correlation peak of unity at $\Delta =0.10$ m confirms the physical coherence of both corridors. We achieve <1 dB error using a small set of field measurements plus simple synthetic data. The method keeps a clear mathematical core and can be extended to other priors, NLOS cases, and semi-open hotspots. Full article

Background: The present study investigated the relation between dental inclination, colorimetric variation, and aesthetic perception according to the modification of incisor inclination. Smile aesthetics, shaped by morphological factors and patient perception, are vital for social attractiveness and treatment success. This study aimed to assess the effect of varying head tilt on the perceived colour of upper central incisors by simulating changes in torque of the tooth, as well as evaluate factors influencing the perception of an aesthetic smile, including morphological characteristics and gingival aesthetic parameters. Methods: The study was comprised of three stages: colour analysis, evaluation of micro- and mini-aesthetic smile features, and an image-based assessment to determine evaluator perceptions and overall smile attractiveness. A sample of 50 students with complete, lesion-free anterior dentition was analysed. To simulate the effect of orthodontic torque changes during colour analysis, subjects tilted their heads downward and upward, representing palatal and buccal crown torque, respectively. Standardized macro-intraoral photographs were captured under controlled lighting conditions using a DSLR camera stabilized on a tripod in the different positions: the neutral head position (p0), 15° upward (p + 15), and 15° downward (p − 15). Digital colour analysis was conducted in the CIELAB colour space (L*, a*, b*). In the next stage, focusing on micro- and mini-aesthetic evaluation, an additional 50 smiles were generated using artificial intelligence via the SmileCloud program—one digitally enhanced smile per subject—complementing the initial set of 50 spontaneous smiles. These 100 smile images were evaluated by 50 laypersons and 50 dentists using a visual analogue scale via an online questionnaire, in order to assess perceptions, determine smile attractiveness, and quantify gingival aesthetic parameters. Results: The statistically significant regression results are as follows: those for the L* values in all three head inclinations: downward (−15 degrees), upward (+15 degrees), and total tilting (−15 to +15 degrees), as well as for the a* values for downward tilting and the b* values for total tilting. When the head is tilted downwards, the central incisors are positioned retrusively, and the L* b* values reveal a darker and more yellowish appearance, whereas, with the head tilted upwards, the central incisors protrude, and L* a* values indicate a brighter and more greenish appear. In the evaluation stage of the smile aesthetics study, no significant differences were observed in the judgments between laypersons and dentists or between males and females. Smiles with a high or average anterior line, parallel arc, upward lip curvature, visible first/second premolars, a smile index of 5.08–5.87, and symmetry score of 1.04 were rated as more attractive. Significant asymmetries were observed between upper dental hemi-quadrants in gingival contour and interdental papilla height, highlighting subtle morphological variations relevant to smile aesthetics. Conclusions: Aesthetic assessment revealed that the findings suggest a measurable impact of head position on dental colour perception and aesthetic evaluation. Evaluator variables including profession and gender exerted negligible effects on aesthetic perception, whereas smile attractiveness features and gingival aesthetic parameters demonstrate significant clinical applicability in patient management. Full article

Structural safety of transmission towers is directly influenced by the behavior of bolted connections at discontinuity joints in the main steel angles. Thus, it is essential to investigate the axial compression behavior of double-shear splice connections of main steel angles. In this study, a total of 10 groups of discontinuous steel angle specimens with double-shear splice connections, comprising eight groups of specimens with the same upper and lower angles and two groups of specimens with different upper and lower angles, were designed and tested in compression. The axial deformation, out-of-plane deflection, and strain at the mid-height of steel angles were measured to analyze the influence of double-shear splice connections on the compression behavior of steel angles. Moreover, comparisons were made among discontinuous steel angles in terms of the ultimate load and the associated deformation to investigate the effects of splice steel ratio, slenderness, bolt spacing, and bolt torque, respectively. Based on the experimental results of steel angles in compression, comparisons with the values calculated using Chinese design codes suggest that present design methods show limited accuracy in calculating the axial compressive load capacity of steel angles with double-shear spliced connections, indicating the necessity for revising the design methods in relevant codes. Full article

Background: This review aimed to assess the association between upper molar distalization using clear aligners (CAs) and structural changes in the temporomandibular joint (TMJ). Methods: On February 20, 2025, the following databases were searched: PubMed, Embase, BASE, Web of Science, and Scopus. Studies were included if they reported on orthodontic treatment with CAs involving upper molar distalization and presented TMJ parameter measurements before and after treatment. The JBI Critical Appraisal Checklist for Quasi-Experimental Studies was used to assess the risk of bias. The collected data were analyzed using the paired t-test, mean difference assessment, and Spearman correlation matrix. Results: A total of 4 articles out of 238 records retrieved were included in the review. The mean age of patients was 23.18–29.80 years, and the treatment duration was 1.90–2.21 years. The most important changes were in the posterior and superior joint spaces (PJS and SJS) (p < 0.05), with SJS increasing in two studies (0.56 and 0.7 mm) and PJS increasing in one and decreasing in another (−0.94 and 0.36 mm). Conclusions: Limited evidence suggests that molar distalization with CAs may influence TMJ dimensions to a small extent. However, the results are inconsistent and require further validation with high-quality studies to draw firm conclusions. Registration: The review was pre-registered using the OpenScience Framework (OSF) on 17 April 2025—osf.io/9xyr8. No funding or conflicts of interest were reported. Full article

We consider mixed Hamming packings, addressing the maximal cardinality of codes with a minimum codeword Hamming distance. We do not rely on any algebraic structure of the alphabets. We extend known-integer linear programming models of the problem to be efficiently tractable using standard ILP solvers. This is achieved by adopting the concept of contact graphs from classical continuous sphere packing problems to the present discrete context, resulting in a reduction technique for the models which enables their efficient solution as well as their decomposition to smaller subproblems. Based on our calculations, we provide a systematic summary of all lower and upper bounds for packings in the smallest Hamming spaces. The known results are reproduced, with some bounds found to be sharp, and the upper bounds improved in some cases. Full article

A major challenge for Li-O₂ batteries is the slow kinetics of oxygen reduction (ORR) and evolution (OER) reactions. This work presents a high-performance Pt₃Rh/C composite cathode where Pt-Rh nanoalloys are uniformly dispersed on 3D nanoporous carbon. The bimetallic architecture demonstrates significantly enhanced ORR/OER activity compared to conventional catalysts. Super P, with a large specific surface area and omnipresent pores with diverse size distribution, provided sufficient storage space for Li₂O₂ and facilitated transport channels for Li⁺ and O₂, while the highly conductive Pt₃Rh NPs optimized catalytic efficiency. XPS reveals a prominent electron transfer process between Pt and Rh; the Rh sites in Pt₃Rh/C alloy can effectively act as electron donors to improve the oxygen/lithium peroxide (O₂/Li₂O₂) redox chemistry in LOB. Therefore, the Pt₃Rh/C electrode shows the minimum overpotential (0.60 V) for efficient oxygen reduction and evolution under an upper-limit capacity of 2000 mAh g⁻¹. This work introduces a Pt₃Rh/C nanoalloy synthesis method that boosts Li-O₂ battery efficiency by accelerating oxygen reaction kinetics. Full article