Blood–Brain Barrier: Latest Research
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Systems Neuroscience".
Deadline for manuscript submissions: 25 November 2025 | Viewed by 26
Special Issue Editors
Interests: BBB (blood–brain barrier); brain; amino acid transport
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The blood–brain barrier (BBB) is part of the brain's protective mechanisms; it is a specialized microvasculature that protects neural tissue by preventing the extravasation of blood products while actively exporting undesirable metabolites from the brain to blood. It allows essential nutrients and minerals to enter and ensures nutrient homeostasis. The endothelial cell’s distinct luminal and abluminal membranes function as part of the neurovascular unit (NVU), which comprises energic vascular endothelial cells, glial cells, pericytes, and microglia as well as closely associated astrocytic processes. In this Special Issue on the BBB, we welcome articles pertaining to recent progress in BBB research from basic structural biology to new emerging therapeutic modalities, including translational predictions between in vivo and in vitro systems, and recent clinical advances across modalities.
Prof. Dr. Richard A. Hawkins
Dr. Jacinthe Gingras
Guest Editors
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Keywords
- central nervous system
- blood–brain barrier transport
- receptor
- transcytosis
- therapeutic
- neurovascular unit
- translation
- development
- disease
- membranes
- astrocytes
- nutrient
- homeostasis
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