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Brain Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Studies on Stroke Care and Rehabilitation

edited by Rosa Grazia Bellomo and Raoul Saggini

submission deadline 25 Apr 2025 | 1 articles | Viewed by 1754 | Submission Open

Keywords: stroke; rehabilitation; neuro-motor rehabilitation; restoring the motor skills of the lower limb; biofeedback; brain injuries; neuroplasticity; neurology

(This special issue belongs to the Section Neurorehabilitation)

Exercise, Nutrition and the Brain

edited by

Marco La Marra

submission deadline 25 Apr 2025 | Viewed by 193 | Submission Open

Keywords: brain health; neuroplasticity; neurodegenerative diseases; physical activity; dietary interventions; nutrients and cognition; mental health; preventive strategies; cognitive performance

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Brain Network Connectivity Analysis in Neuroscience

edited by

Mukesh Dhamala

and Sahil Bajaj

submission deadline 30 Apr 2025 | 9 articles | Viewed by 15857 | Submission Open

Keywords: brain connectivity; brain networks; brain dynamics; brain network interactions; brain organization; fMRI; DTI; EEG; MEG; iEEG; fNIRS; cognitive functions; brain dysfunctions; brain disorders; whole-brain connectivity

(This special issue belongs to the Section Computational Neuroscience and Neuroinformatics)

Plasticity and Regeneration in the Olfactory System

edited by

Claire E. Cheetham

submission deadline 30 Apr 2025 | 2 articles | Viewed by 3978 | Submission Open

Keywords: olfactory; plasticity; regeneration; neurogenesis

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Brain Structural and Functional Correlates of Addiction

edited by

Chella Kamarajan

submission deadline 30 Apr 2025 | 2 articles | Viewed by 3719 | Submission Open

Keywords: addiction; substance use disorders (SUDs); behavioral addiction; EEG; brain oscillations; MRI; brain imaging; brain stimulation; cognitive function; brain networks

(This special issue belongs to the Section Behavioral Neuroscience)

Brain Metastases: Updates and Future Directions

edited by Aristotelis Kalyvas and Enrique Gutierrez-Valencia

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1668 | Submission Open

Keywords: brain metastases; targeted therapy; immunotherapy; artificial intelligence; neurosurgery; radiosurgery; biomarkers

(This special issue belongs to the Section Neuro-oncology)

Olfactory System and Brain Diseases: Investigating the Related Structures, Neurocircuits, and Functional Mechanisms

edited by David M. Coppola

submission deadline 30 Apr 2025 | 2 articles | Viewed by 1625 | Submission Open

Keywords: Alzheimer’ s; Parkinson’ s; Huntington’ s; MS; depression; anxiety; disorder; olfactory bulbectomy; anosmia; smell

(This special issue belongs to the Section Systems Neuroscience)

CNS Developmental Issues (DOHAD Concept) Associated with Exposure to Pollutants during Gestation, Lactation/Infancy or Adolescence

edited by Alex Manhães

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1351 | Submission Open

Keywords: nervous system; development; pollution; microplastics and nanoplastics; bisphenol; pesticides; PFAS/PFOS; petrochemicals

(This special issue belongs to the Section Environmental Neuroscience)

The Effects of Adverse Childhood Experiences on Emotional and Mental Health

edited by Carmen Alvarez

submission deadline 30 Apr 2025 | Viewed by 643 | Submission Open

Keywords: adverse childhood experiences; emotional health; mental health; stress regulation; brain health

(This special issue belongs to the Section Neuropsychiatry)

Substance Abuse in the Psychiatric Population

edited by

Michael Fritz

and

Marc Fakhoury

submission deadline 30 Apr 2025 | Viewed by 211 | Submission Open

Keywords: substance abuse disorder; genetics (expression; SNPs); epigenetics; schizophrenia; forensic psychiatry; depression; bipolar disorder; translational research; personality disorders; imaging (PET; SPECT; MRI); general psychiatry

(This special issue belongs to the Section Neuropsychiatry)

Molecular Mechanisms and Biomarkers of Substance Use Disorders

edited by Ming-Fen Ho

submission deadline 30 Apr 2025 | Viewed by 190 | Submission Open

Keywords: substance use disorders; biomarkers; multi-omics; molecular mechanisms; precision medicine

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

A Window to the Brain: Research in Neuro-Ophthalmology—Focus on The Retina

edited by

Arieh S Solomon

submission deadline 30 Apr 2025 | Viewed by 104 | Submission Open

Keywords: morphology; electrophysiology; biochemistry; metabolic; autoimmune; vascular; degenerative; glaucoma; genetic; myopia; strabismus; intraocular implants; sub retinal implants; external optical devices; imaging; medications

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Mind in Motion: Exploring Neuropsychophysiological Aspects of Sports Performance, Health and Physical Activity

edited by

Ricardo De La Vega Marcos

submission deadline 1 May 2025 | 6 articles | Viewed by 10444 | Submission Open

Keywords: neuropsychophysiology; sports performance; physical activity; brain– body interaction; psychophysiological responses; health and well-being

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Advances in Non-Invasive Brain Stimulation

edited by Mariagiovanna Cantone and

Giuseppe Lanza

submission deadline 1 May 2025 | 1 articles | Viewed by 3995 | Submission Open

Keywords: translational neuroscience; clinical neurophysiology; neurodegeneration; neural plasticity; neurosonology; sleep disorders; cognitive decline; non-invasive brain stimulation; nutraceuticals; neurogenetics; transcranial magnetic stimulation; dementia; vascular cognitive impairment; stroke; depression; metaplasticity; motor cortex; motor learning; neurotrophins; transcranial-focused ultrasound

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Advanced Clinical Diagnosis, Evaluation, and Treatment of Psychosis

edited by Giulia Menculini and

Gaia Sampogna

submission deadline 5 May 2025 | 4 articles | Viewed by 6204 | Submission Open

Keywords: psychotic disorders; affective psychoses; schizophrenia; antipsychotic drugs; psychosocial treatments; at-risk mental states; biomarkers; early intervention; prevention; social psychiatry

(This special issue belongs to the Section Neuropsychiatry)

Sensory Function and Perception in Dementia

edited by

Andrea Tales

submission deadline 5 May 2025 | 1 articles | Viewed by 1550 | Submission Open

Keywords: ageing ; cognitive decline ; objectively measured effects of sensory dysfunction in people with cognitive decline ; subjective reports of sensory dysfunction in people with cognitive decline

(This special issue belongs to the Section Neurodegenerative Diseases)

The Latest Research on Drug Treatment of Epilepsy

edited by Alberto E. Musto and Luis Pacheco

submission deadline 5 May 2025 | Viewed by 175 | Submission Open

Keywords: epilepsy; neuroinflammation; seizures; cannabinoid

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Stress, Resilience and Susceptibility

edited by Elaine Gavioli

submission deadline 15 May 2025 | 3 articles | Viewed by 3090 | Submission Open

Keywords: stress; resilience; vulnerability; psychiatric disorders; biomarkers

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Non-Invasive Brain Stimulation in Neurological Diseases and Neurorehabilitation

edited by

Maryam Zoghi

submission deadline 15 May 2025 | Viewed by 377 | Submission Open

Keywords: non-invasive brain stimulation; transcranial direct-current stimulation; transcranial magnetic stimulation; neurorehabilitation; neurological diseases; stroke; Parkinson's disease; multiple sclerosis; chronic pain

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Molecular and Cellular Biology of Brain Tumors and Neuro-Oncology

edited by Rafael Roesler

submission deadline 16 May 2025 | 1 articles | Viewed by 1657 | Submission Open

Keywords: glioma; medulloblastoma; ependymoma; brain cancer; central nervous system tumor; neuro-oncology

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Current Perspectives on the Management of Acute-Phase Ischemic Stroke

edited by Stefano Caproni, Ettore Nicolini and Soffien Ajmi

submission deadline 16 May 2025 | 1 articles | Viewed by 646 | Submission Open

Keywords: acute ischemic stroke; endovascular thrombectomy; thrombolysis; clinical treatment

(This special issue belongs to the Section Neurorehabilitation)

The Application of EEG in Neurorehabilitation

edited by

Ryouhei Ishii

submission deadline 19 May 2025 | 7 articles | Viewed by 7026 | Submission Open

Keywords: electroencephalography (EEG); neurorehabilitation; neural plasticity; personalized treat-ment strategies; brain– computer interfaces

(This special issue belongs to the Section Computational Neuroscience and Neuroinformatics)

So, What? What Does Contemporary ADHD Research Tell Us about Lived Experiences?

edited by

Conor Mc Guckin

, Kate Carr-Fanning and Aoife Lynam

submission deadline 19 May 2025 | 1 articles | Viewed by 1314 | Submission Open

Keywords: ADHD; social model; participant voice; educational inclusion; social inclusion; transition planning; family experience; early intervention; policy; advocacy

(This special issue belongs to the Section Developmental Neuroscience)

Advances in the Pharmacologic Treatment of Depression, Anxiety, and Other Psychiatric Disorders

edited by Danielle S. Cha

submission deadline 20 May 2025 | Viewed by 186 | Submission Open

Keywords: mental health; mental illness; treatment; hypothesis driven; burden of disease

(This special issue belongs to the Section Neuropsychiatry)

Mechanisms That Support Music Learning and Development

edited by Jennifer A. Bugos

submission deadline 20 May 2025 | Viewed by 125 | Submission Open

Keywords: music; music therapy; neurophysiological research; cognitive development; music cognition; performance; auditory processing

(This special issue belongs to the Section Behavioral Neuroscience)

Neuromodulation and Neurostimulation in Psychiatric Disorders

edited by

Takuma Inagawa

submission deadline 25 May 2025 | 2 articles | Viewed by 2600 | Submission Open

Keywords: brain stimulation; rTMS; ECT; depression; OCD

(This special issue belongs to the Section Neuropsychiatry)

Anosognosia and the Determinants of Self-Awareness

edited by

Guido Gainotti

submission deadline 25 May 2025 | 1 articles | Viewed by 631 | Submission Open

Keywords: anosognosia; disease unawareness; stroke patients; Alzheimer’ s disease; self-awareness; hemiplegia; unilateral neglect; Anton syndrome; insight

(This special issue belongs to the Section Neuropsychology)

Genetics of Neurodegenerative Diseases: Retrospect and Prospect

edited by

Kallirhoe Kalinderi

and

Vasileios T. Papaliagkas

submission deadline 30 May 2025 | 2 articles | Viewed by 4012 | Submission Open

Keywords: Alzheimer's disease (AD); Parkinson's disease (PD); amyotrophic lateral sclerosis (ALS); multiple sclerosis; neurodegeneration; protein aggregation; therapy; pharmacogenetics; gene; nutrigenomics

(This special issue belongs to the Section Neurodegenerative Diseases)

Diagnosis, Treatment, and Prognosis of Neuromuscular Disorders

edited by

Vincenzo Di Stefano

and

Claudia Vinciguerra

submission deadline 30 May 2025 | 2 articles | Viewed by 3659 | Submission Open

Keywords: neuromuscular disorders; neurogenetics; neuroimmunology; polyneuropathy; myopathy; neuromuscular junction disease; diagnosis; prognosis; treatment; rehabilitation

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Novel Neuroimaging of Neurological and Psychiatric Disorders

edited by

Darrin J. Lee

submission deadline 30 May 2025 | Viewed by 203 | Submission Open

Keywords: neuroimaging; diagnosis; treatment; psychiatric diseases; brain structure

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Headache: Advances in Pathophysiology, Clinical Presentations and Therapeutic Options

edited by

Alessandro Viganò

submission deadline 30 May 2025 | Viewed by 164 | Submission Open

Keywords: migraine; comorbidities; pathophysiology; pharmacological interventions; non-pharmacological interventions; mechanisms

(This special issue belongs to the Section Systems Neuroscience)

Diagnosis, Therapy and Rehabilitation in Neuromuscular Diseases

edited by

Vincenzo Donadio

submission deadline 31 May 2025 | 7 articles | Viewed by 14860 | Submission Open

Keywords: neuromuscular diseases; autonomic dysfunctions; pain; small fiber neuropathies; Fabry disease; hereditary transthyretin amyloidosis; myasthenic disorders; myopathies; diagnosis and treatment

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Aging-Related Changes in Memory and Cognition

edited by Anna Christakou

submission deadline 31 May 2025 | 5 articles | Viewed by 5038 | Submission Open

Keywords: aging; quality of life; cognitive/physical health; neurodegenerative diseases; geriatric physiotherapy; memory; cognition; attention; prevention; therapeutic treatments

(This special issue belongs to the Section Neurodegenerative Diseases)

Brain Tumors: From Molecular Basis to Therapy

edited by Paolo Tini and Giuseppe Minniti

submission deadline 31 May 2025 | 4 articles | Viewed by 4133 | Submission Open

Keywords: brain tumors; molecular pathways; targeted therapy; diagnostic biomarkers; predictive biomarkers; therapeutic resistance

(This special issue belongs to the Section Neuro-oncology)

Relationships Between Disordered Sleep and Mental Health

edited by Anne M. Fink

submission deadline 31 May 2025 | 2 articles | Viewed by 3305 | Submission Open

Keywords: circadian rhythms; depression; genetics and genomics; rapid eye movement sleep behavior disorder; schizophrenia; sleep deprivation; shift– work sleep disorder; substance use disorder; suicide

(This special issue belongs to the Section Neuropsychiatry)

Brain Stimulation Treatments for Memory Disorders

edited by

Windy McNerney

and

John Philip Coetzee

submission deadline 31 May 2025 | 1 articles | Viewed by 1202 | Submission Open

Keywords: DBS; tACS; tDCS; TUS; memory loss; plasticity; cognition; biochemistry

(This special issue belongs to the Section Systems Neuroscience)

The Gut–Brain Axis: Exploring the Interactions Between the Microbiota and the Nervous System

edited by Kyle Gobrogge

submission deadline 1 Jun 2025 | 1 articles | Viewed by 977 | Submission Open

Keywords: gut– brain axis; microbiota– neuron interactions; neurological functions and disorders; animal models; behavior and cognition

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

State of the Art in Multisensory Integration: Predicting Age-Related Clinical Outcomes

edited by Jeannette R. Mahoney

submission deadline 1 Jun 2025 | 1 articles | Viewed by 921 | Submission Open

Keywords: multisensory integration; sensorimotor integration; aging; mobility; balance; falls; cognition; dementia

(This special issue belongs to the Section Sensory and Motor Neuroscience)

The Use of Chemogenetics and Optogenetics on Understanding the Neurobiology of Brain Disorders

edited by

Sandesh Panthi

and

Marc Ekker

submission deadline 6 Jun 2025 | Viewed by 651 | Submission Open

Keywords: chemogenetics; optogenetics; DREADDs; brain disorders; neurobiology of disease

From Bench to Bedside: Motor–Cognitive Interactions—2nd Edition

edited by

Daniele Corbo

submission deadline 10 Jun 2025 | 3 articles | Viewed by 4240 | Submission Open

Keywords: motor control and motor learning; movement; cognitive functions; falls; diagnosis; intervention; cognitive– motor training; cognition; fMRI

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Current Research in Neurosurgery

edited by

Roberto Altieri

, Manlio Barbarisi and Lucas Alverne Freitas De Albuquerque

submission deadline 10 Jun 2025 | 3 articles | Viewed by 2862 | Submission Open

Keywords: CSN tumor; glioblastoma; skull base; vertebral metastasis; spinal surgery; cerebral aneurysm; AVM; cavernoma; epilepsy

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Biomarkers in Neurodegenerative Diseases: Advancements and Future Directions

edited by Fausto Roveta

submission deadline 10 Jun 2025 | Viewed by 278 | Submission Open

Keywords: Alzheimer’ s disease; Parkinson’ s disease; neurodegenerative disorders; biomarkers; neuroimaging

(This special issue belongs to the Section Neurodegenerative Diseases)

Role of Inflammation, Oxidative Stress, and Metabolic Dysfunction in Neurodevelopmental and Neurodegenerative Diseases: Pharmacological Targets and Therapeutic Interventions

edited by

Ansab Akhtar

submission deadline 13 Jun 2025 | 5 articles | Viewed by 8653 | Submission Open

Keywords: neuroinflammation; oxidative stress; mitochondrial dysfunction; metabolism; metabolomics; neurodegenerative diseases; neurodevelopmental diseases; pharmacological targets; potential drugs

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Mental Health: From a Neurobiology Perspective

edited by

Zuleide Maria Ignácio

and

Margarete Dulce Bagatini

submission deadline 13 Jun 2025 | 2 articles | Viewed by 4116 | Submission Open

Keywords: neurobiology; mental health; psychiatric disorders; neurotransmission; signaling pathway; genetic and epigenetic factors; neurodevelopment; inflammation; therapeutic interventions; translational and clinical research

(This special issue belongs to the Section Neuropsychiatry)

Exploration of the Brain Structural Changes in Patients with Mental Illness

edited by

Fengyu Zhang

submission deadline 15 Jun 2025 | Viewed by 264 | Submission Open

Keywords: psychiatric diseases; human brain connectome; biomarkers; endophenotypes

(This special issue belongs to the Section Neuropsychiatry)

Heterogeneity in Cognitive Aging: From Healthy Aging to Neurodegenerative Disease

edited by Yuta Katsumi,

Deepti Putcha

and Bradford C. Dickerson

submission deadline 15 Jun 2025 | Viewed by 170 | Submission Open

Keywords: aging; cognition; cognitive impairment; subjective cognitive decline; neurodegeneration; Alzheimer’ s disease; prognostication; brain imaging; neuromodulation; interventions

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

New Challenges in the Study of Cognitive Impairment in Parkinson’s Disease

edited by

Sonia Di Tella

and Laura Colautti

submission deadline 16 Jun 2025 | 2 articles | Viewed by 3425 | Submission Open

Keywords: Parkinson’ s disease; cognitive impairment; assessment; intervention; executive functions; learning; decision making; creativity; cognitive reserve

(This special issue belongs to the Section Neurodegenerative Diseases)

Prediction and Prevention of Psychotic Disorders

edited by Francesco Monaco and Annarita Vignapiano

submission deadline 20 Jun 2025 | 1 articles | Viewed by 2339 | Submission Open

Keywords: psychotic disorders; early identification; prevention; biomarkers; genetics; psychosocial interventions

(This special issue belongs to the Section Neuropsychiatry)

Neuropsychological Impact and Quality of Life in Chronic Illness

edited by

Nicoletta Ciccarelli

submission deadline 20 Jun 2025 | 1 articles | Viewed by 538 | Submission Open

Keywords: chronic disease; HIV; cancer; cardiovascular disease; neurodegeneration; aging; cognitive impairment; cognitive evaluation; quality of life; patient reported outcome (PRO) measures

(This special issue belongs to the Section Neuropsychology)

Neurofunctional Basis of Language Processing—2nd Edition

edited by

Roozbeh Rezaie

and