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Brain Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Focus on Mental Health and Mental Illness in Adolescents

edited by

Dariusz Krok

submission deadline 30 Sep 2025 | 9 articles | Viewed by 49654 | Submission Open

Keywords: mental health; mental illness; adolescents; coping with stress; psychotherapy; medical treatment; well-being

(This special issue belongs to the Section Neuropsychiatry)

New Insights into Movement Generation: Sensorimotor Processes

edited by

Koichi Hiraoka

submission deadline 30 Sep 2025 | 9 articles | Viewed by 20241 | Submission Open

Keywords: motor plan; somatosensation; sensory– motor integration; feedback; vision; motor execution; movement; motor control; stimulus– response mapping

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Editorial Board Collection Series: Insight into Neurosurgery

edited by

Massimiliano Visocchi

and

Francesco Signorelli

submission deadline 30 Sep 2025 | 5 articles | Viewed by 10620 | Submission Open

Keywords: brain; skull base; craniocervical junction; spine and spinal cord; demolition reconstruction

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

The Perils of Social Media Addiction

edited by Mike Zhengyu Yao

submission deadline 30 Sep 2025 | 2 articles | Viewed by 4620 | Submission Open

Keywords: social media addiction; digital dependency; internet addiction; device dependency; mental health and technology; mental health interventions; digital well-being

(This special issue belongs to the Section Neuropsychiatry)

Contemporary Spinal Surgery: Surgical Optimization and Technological Innovation

edited by

Nicola Montemurro

and Francesco Acerbi

submission deadline 30 Sep 2025 | 3 articles | Viewed by 3651 | Submission Open

Keywords: minimally invasive techniques; telehealth; spinal vascular malformation; spinal tumor; 3D printing; surgical planning; artificial intelligence; endoscopy in spine surgery

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Language Dysfunction in Posterior Cortical Atrophy

edited by

Deepti Putcha

submission deadline 30 Sep 2025 | 2 articles | Viewed by 2860 | Submission Open

Keywords: Alzheimer’ s disease; atypical AD; visual variant; posterior cortical atrophy; reading; spelling; writing; visual; visuospatial

(This special issue belongs to the Section Neurodegenerative Diseases)

From Neurodevelopment to Mental Health: New Insight on Psychiatric Disorders Among Children, Adolescents and Young Adults

edited by

Maria Giuseppina Petruzzelli

Emilia Matera

and Alessandra Gabellone

submission deadline 30 Sep 2025 | 1 articles | Viewed by 821 | Submission Open

Keywords: childhood; adolescence; neurodevelopment; psychopathological onset; mental health; developmental trajectory; neurobiology; early interventions; clinical overlap; environmental risk factors; diagnostic process

(This special issue belongs to the Section Neuropsychiatry)

Nanomedicine in Neurological Disorders

edited by

Mariana Matias

and

Márcio Rodrigues

submission deadline 30 Sep 2025 | Viewed by 252 | Submission Open

Keywords: neurological disorders; neuropharmacology; preclinical studies; efficacy and safety assessment; nanomedicines; nanotechnology; brain

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

The Development of Prosociality: From Philosophy to Neuroscience

edited by Bahia Guellaï and

Mayilin Moreno

submission deadline 30 Sep 2025 | Viewed by 228 | Submission Open

Keywords: prosociality; development; interdisciplinarity; social neurosciences

(This special issue belongs to the Section Developmental Neuroscience)

From Satiety to Psychiatry: Exploring the Role of GLP-1 Receptor Agonists in Mental Health, Substance Use and Neuropsychiatric Disorders

edited by

Davide Arillotta

Giuseppe Floresta

and

Fabrizio Schifano

submission deadline 3 Oct 2025 | 1 articles | Viewed by 4783 | Submission Open

Keywords: GLP-1 receptor agonists (GLP-1 RAs); dual GIP/GLP-1 agonists; reward; craving; behavioral addictions; mental health; psychiatry; substance use disorders; semaglutide; tirzepatide

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

The Retina, Visual Function and Circadian Involvement in Parkinson’s Disease

edited by Gregory L. Willis

submission deadline 10 Oct 2025 | 1 articles | Viewed by 337 | Submission Open

Keywords: Parkinson’ s disease; retina; circadian; dopamine; melatonin; prodromal; vision

(This special issue belongs to the Section Neurodegenerative Diseases)

Research on Cannabis and Other Substance Abuse: Neurological Insights

edited by Patricia Di Ciano

submission deadline 10 Oct 2025 | Viewed by 247 | Submission Open

Keywords: cannabis; cocaine; opioids; amphetamine; tobacco; brain imaging; driving; cognition; diagnosis; treatment; harm reduction; legalization

(This special issue belongs to the Section Behavioral Neuroscience)

Noninvasive Neuromodulation Applications in Research and Clinics

edited by

Mehran Emadi Andani

and Fatemeh B. Yavari

submission deadline 15 Oct 2025 | 4 articles | Viewed by 10137 | Submission Open

Keywords: transcranial brain stimulation (TBS); transcranial magnetic stimulation (TMS; rTMS; iTBS; and cTBS); transcranial electrical stimulation (tDCS; tACS; and tRNS); transcranial focused ultrasound stimulation (tFUS); transcranial vagus nerve stimulation (tVNS); virtual reality effect on the brain states; TBS applications in neuromotor disease (Parkinson’ s disease and Huntington’ s disease); TBS applications in mental disease (Alzheimer disease and Dementia); TBS application on functional brain mapping (TMS brain mapping); clinical application of brain stimulation in motor symptoms in PD patients (tremor; gait; bradykinesia; postural instability; rigidity; handwriting; etc.); clinical application of brain stimulation in non-motor symptoms (cognitive; psychosis; neuropsychiatric; etc.); safety of brain stimulation

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Diagnosis, Treatment, and Prognosis of Neuromuscular Disorders

edited by

Vincenzo Di Stefano

and

Claudia Vinciguerra

submission deadline 15 Oct 2025 | 5 articles | Viewed by 9194 | Submission Open

Keywords: neuromuscular disorders; neurogenetics; neuroimmunology; polyneuropathy; myopathy; neuromuscular junction disease; diagnosis; prognosis; treatment; rehabilitation

(This special issue belongs to the Section Sensory and Motor Neuroscience)

New Horizons in Dystonia Research

edited by Nicoletta Manzo

submission deadline 15 Oct 2025 | Viewed by 186 | Submission Open

Keywords: dystonia; neurophysiology; movement disorders; brain stimulation; botulinum toxin injection

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Innovations in Pediatric Functional Neurosurgery

edited by Samuel Tomlinson and Benjamin C. Kennedy

submission deadline 15 Oct 2025 | Viewed by 147 | Submission Open

Keywords: pediatric neurosurgery; functional neurosurgery; epilepsy; movement disorders; spasticity; dystonia; surgical innovation; minimally invasive surgery

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Advances in Educational Neuroscience: Current Status and Future Directions

edited by

Antonio Luque De La Rosa

, Alejandro Vargas Serrano and Celia Gallardo Herrerías

submission deadline 17 Oct 2025 | 6 articles | Viewed by 23959 | Submission Open

Keywords: educational neuroscience; cognitive development; pedagogical strategies; student diversity; inclusive learning; neuroscientific applications; educational research; neuroscience-based interventions; innovative educational practices; theoretical and empirical approaches

(This special issue belongs to the Section Developmental Neuroscience)

Clinical Management of Cognitive Disorders in Neurodegenerative Patients

edited by

Viviana Lo Buono

submission deadline 17 Oct 2025 | 1 articles | Viewed by 3232 | Submission Open

Keywords: neurodegenerative disorders; cognitive impairment; cognitive rehabilitation; dementia; multiple sclerosis; Parkinson’ s disease; Huntington corea; TMS

(This special issue belongs to the Section Neurorehabilitation)

New Insights Into the Treatment of Subjective Tinnitus

edited by Mark N. Wallace

submission deadline 20 Oct 2025 | Viewed by 351 | Submission Open

Keywords: tinnitus neurobiology; tinnitus pathophysiology; non-invasive electrical stimulation; bimodal therapy; pharmacotherapy; tinnitus management; neurorehabilitation

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Artificial Intelligence (AI) in Sleep Medicine

edited by

Shahab Haghayegh

submission deadline 20 Oct 2025 | Viewed by 319 | Submission Open

Keywords: artificial intelligence; sleep medicine; machine learning; health prediction; sleep monitoring

(This special issue belongs to the Section Sleep and Circadian Neuroscience)

Computational Intelligence and Brain Plasticity

edited by

Gianluca Borghini

, Riccardo Barbieri, Viviana Mucci, Hong Zeng and

Alessandra Anzolin

submission deadline 24 Oct 2025 | 5 articles | Viewed by 13481 | Submission Open

Keywords: brain plasticity; learning process; cognitive training; mental state assessment; cognitive rehabilitation; high-resolution eeg; brain connectivity; cognitive control behaviour; artificial intelligence; hypers-canning; multivariate autoregressive models

(This special issue belongs to the Section Computational Neuroscience, Neuroinformatics, and Neurocomputing)

Mechanisms Underlying the Neuropathic/Chronic Pain Development and Maintenance: Focus on Pharmacological Targets and Therapeutic Approaches

edited by

Giada Amodeo

submission deadline 25 Oct 2025 | 2 articles | Viewed by 4534 | Submission Open

Keywords: neuropathic pain; chronic pain; mood alteration; neurons; glia cells; cytokines; neuroinflammation

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Contributions of Multisensory Processing and Integration in Successful Ageing

edited by Argiro Vatakis

submission deadline 25 Oct 2025 | Viewed by 289 | Submission Open

Keywords: multisensory; sensory; ageing; multisensory integration; multisensory processing; healthy ageing

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Stroke: Epidemiology, Diagnosis, Etiology, Treatment, and Prevention

edited by Rubens José Gagliardi

submission deadline 30 Oct 2025 | Viewed by 302 | Submission Open

Keywords: stroke; cerebrovascular disease; epidemiology; thrombolysis; thrombectomy; risk factors; ischemia

(This special issue belongs to the Section Neurodegenerative Diseases)

Editorial Board Collection Series: Advances in Neuro-Oncology

edited by

Terry Lichtor

submission deadline 31 Oct 2025 | 9 articles | Viewed by 11562 | Submission Open

Keywords: brain tumors; gliomas; cytokine gene vaccine therapy; immunotherapy; angiogenesis; checkpoint inhibitors; dendritic cell therapy

(This special issue belongs to the Section Neuro-oncology)

How to Rewire the Brain—Neuroplasticity

edited by

Jianyang Du

and Hui Lu

submission deadline 31 Oct 2025 | 4 articles | Viewed by 10687 | Submission Open

Keywords: brain circuits; neural networks; synaptic plasticity; neural development; network dynamics; neural coding; information processing; neuron– glia interaction; behavioral output; neurological disorders

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Advances in Non-Invasive Brain Stimulation

edited by

Mariagiovanna Cantone

and

Giuseppe Lanza

submission deadline 31 Oct 2025 | 2 articles | Viewed by 9863 | Submission Open

Keywords: translational neuroscience; clinical neurophysiology; neurodegeneration; neural plasticity; neurosonology; sleep disorders; cognitive decline; non-invasive brain stimulation; nutraceuticals; neurogenetics; transcranial magnetic stimulation; dementia; vascular cognitive impairment; stroke; depression; metaplasticity; motor cortex; motor learning; neurotrophins; transcranial-focused ultrasound

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Molecular and Neuroimaging Biomarkers in Alzheimer’s Disease and Frontotemporal Lobar Degeneration

edited by

Rodolfo Gabriel Gatto

submission deadline 31 Oct 2025 | 2 articles | Viewed by 4572 | Submission Open

Keywords: neuroimaging; biomarkers; genetic and molecular biology; connectomics; neuropathology; neuropsychological measures; dementia; preclinical models; alzheimer’ s disease; frontotemporal dementia

(This special issue belongs to the Section Neurodegenerative Diseases)

Modulating Brain Network Dynamics Through Training: Impacts on Perception, Cognition, and Action in Health and Disorder

edited by

Mukesh Dhamala

submission deadline 31 Oct 2025 | 1 articles | Viewed by 4180 | Submission Open

Keywords: perception; cognition; motor actions; behavioral training; music; video game playing; neuroimaging; computational models; physical exercise

(This special issue belongs to the Section Behavioral Neuroscience)

Neuroimaging and Biomarker-Guided Neuromodulation: Advances in Personalized Brain and Autonomic Stimulation

edited by Mohsen Mosayebi-Samani and

Desmond Agboada

submission deadline 31 Oct 2025 | 2 articles | Viewed by 2223 | Submission Open

Keywords: neuromodulation; brain stimulation; autonomic regulation; neuroimaging; biomarkers; AI-driven Closed-loop Systems; transcranial magnetic stimulation (TMS); transcranial direct current stimulation (tDCS); transcranial alternating current stimulation (tACS); deep brain stimulation (DBS); transcranial ultrasound stimulation (TUS); vagus nerve stimulation (tVNS); heart rate variability (HRV); biofeedback; magnetic resonance imaging (MRI); electroencephalography (EEG); functional near-infrared spectroscopy (fNIRS); epilepsy; depression; stroke; Alzheimer; PTSD; anxiety

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Understanding Human Social Cognition: Integration of Neural, Cognitive, Behavioral, Affective, and Social Determinants

edited by

Eduar Herrera

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1328 | Submission Open

Keywords: social cognition; neural; cognitive; affective; social determinants

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Exploring the Neurobiology of the Sensory-Motor System

edited by

Daya Shankar Gupta

and Hubert Löffler

submission deadline 31 Oct 2025 | 1 articles | Viewed by 774 | Submission Open

Keywords: sensory; perception; motor; execution; cognitive functions; space of the brain; temporal-spatial; time dimension

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Emotional Recognition and Behavioral Regulation: An Integral Perspective

edited by

Ángel Romero Martínez

submission deadline 31 Oct 2025 | 1 articles | Viewed by 728 | Submission Open

Keywords: behavioral regulation; emotion decoding; emotion recognition; mental disorders; personality disorders; violence

(This special issue belongs to the Section Neuropsychology)

Advancements and Future Directions in Real-Time fMRI Neurofeedback Research

edited by Meghan Martz, Scott Peltier and Stefanie Russman Block

submission deadline 31 Oct 2025 | Viewed by 437 | Submission Open

Keywords: neurofeedback; real-time fMRI; neuromodulation; imaging methods; self-regulation

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

The Impact of Self and Reward on Cognitive Processes

edited by Ada Kritikos

submission deadline 31 Oct 2025 | Viewed by 356 | Submission Open

Keywords: self-prioritisation; memory self-reference effects; source and recognition memory; decision making; value modulated attentional capture; reward bias; ownership; self-evaluation

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

From Diagnosis to Care: Cognitive Challenges and Innovations in Multiple Sclerosis

edited by

Adriana Aguayo-Arelis

and Brenda Viridiana Rabago-Barajas

submission deadline 31 Oct 2025 | Viewed by 166 | Submission Open

Keywords: multiple sclerosis; neuropsychological diagnosis; diagnostic biomarkers; cognition and care; research on neurodegenerative diseases

(This special issue belongs to the Section Systems Neuroscience)

Ferroptosis in Epilepsy: From Molecular Mechanisms to Possible Therapeutic Alternatives

edited by

Alberto Lazarowski

and Jerónimo Andrés Auzmendi

submission deadline 31 Oct 2025 | Viewed by 130 | Submission Open

Keywords: epilepsy; ferroptosis; hypoxia; brain parenchyma; peripheral organs; iron metabolism; transferrin; hemosiderin

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Artificial Intelligence in Neuropsychology: Advancing Diagnosis, Personalized Treatment, and Predictive Modeling

edited by

Sara Palermo

submission deadline 1 Nov 2025 | Viewed by 320 | Submission Open

Keywords: AI-driven diagnostic tools; personalized treatment; machine learning predictive modeling; data analysis; mental health and rehabilitation; decision support systems

(This special issue belongs to the Section Neuropsychology)

The Neural Processes Underlying Parkinson’s Disease and Related Synucleinopathies

edited by Danielle E. Mor

submission deadline 5 Nov 2025 | Viewed by 253 | Submission Open

Keywords: α -synuclein; synucleinopathies; Parkinson’ s disease; dementia with Lewy bodies; multiple system atrophy; neurodegeneration; protein aggregation

(This special issue belongs to the Section Neurodegenerative Diseases)

Application of MRI in Brain Diseases

edited by

Carlo A. Mallio

Gianfranco Di Gennaro

and Andrea Elefante

submission deadline 6 Nov 2025 | 6 articles | Viewed by 5818 | Submission Open

Keywords: magnetic resonance imaging (MRI); medical imaging; neurological disorders; mental disorders; brain diseases; diagnosis; treatment

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Clinical Studies in Alcohol Use Disorders

edited by Łukasz Mokros and

Katarzyna Nowakowska-Domagała

submission deadline 10 Nov 2025 | Viewed by 607 | Submission Open

Keywords: AUD; suicide; suicidality; sleep; circadian rhythm; addiction therapy; cognitive functions; psychotherapy; trauma

(This special issue belongs to the Section Behavioral Neuroscience)

Deep into the Brain: Artificial Intelligence in Brain Diseases—2nd Edition

edited by

Gianluca Borghini

Pietro Aricò

Gaia Romana Pellicano

and

Alessandra Anzolin

submission deadline 15 Nov 2025 | 4 articles | Viewed by 10102 | Submission Open

Keywords: artificial intelligence; brain diseases; neurological disorders; machine learning; deep learning; neuroimaging; neuroscience; neurophysiological measures; mental states; multimodal approach

(This special issue belongs to the Section Computational Neuroscience, Neuroinformatics, and Neurocomputing)

New Advances in Surgical Treatment of Brain Injury

edited by

Andres M. Rubiano

and Luigi Valentino Berra

submission deadline 15 Nov 2025 | 1 articles | Viewed by 2964 | Submission Open

Keywords: traumatic brain injury; intracranial compartment syndrome; invasive monitoring; non-invasive neuroimaging; decompressive craniectomy; expansion craniotomy; hinge craniotomy; endoscopic neurosurgery; brain injury management

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Molecular Genetics of Neurodevelopment Disorders

edited by

Constance Smith-Hicks

and

Philip H. Iffland

submission deadline 15 Nov 2025 | 1 articles | Viewed by 1095 | Submission Open

Keywords: genotype– phenotype correlations; epigenetics; genome editing; translational research; neuroethics; deep sequencing; functional genomics

(This special issue belongs to the Section Developmental Neuroscience)

The Interplay Between the Brain, Behavior and Immunity

edited by

Fatme Seval Ismail

submission deadline 15 Nov 2025 | Viewed by 251 | Submission Open

Keywords: behavior; therapy; drugs; immunity; neuroinflammation; neurological/psychiatric disorders; clinical studies; in vivo/in vitro models

(This special issue belongs to the Section Behavioral Neuroscience)

Using Neuroimaging Techniques to Explore the Diagnosis and Treatment of Epilepsy

edited by Friedhelm C. Schmitt

submission deadline 15 Nov 2025 | Viewed by 72 | Submission Open

Keywords: neuroimaging; epilepsy; MRI; PET; MEG

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Computational Neuroscience and Artificial Intelligence: Cross-Talks and Interrelated Contributions

edited by

Ali Yadollahpour

submission deadline 17 Nov 2025 | 5 articles | Viewed by 9251 | Submission Open

Keywords: computational neuroscience; cognitive neuroscience; artificial intelligence; machine learning; precision medicine; early diagnosis; treatment

(This special issue belongs to the Section Computational Neuroscience, Neuroinformatics, and Neurocomputing)

Translational Omics in Neurodegenerative and Neurodevelopmental Disorders

edited by

Shiek S.S.J. Ahmed

and

Prabu Paramasivam

submission deadline 17 Nov 2025 | 3 articles | Viewed by 8574 | Submission Open

Keywords: Neurodegeneration; Neurodevelopment; Omics; Translation regulation; Diagnostic biomarkers; Therapeutic targets

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Retinal Neurochemistry and Development

edited by Roberto Paes-de-Carvalho and Sriparna Majumdar

submission deadline 20 Nov 2025 | 5 articles | Viewed by 5742 | Submission Open

Keywords: retina; neurochemistry; development; neurotransmitter; signaling pathways; cultures; neuron– glia interactions; synapses; neuronal differentiation; neuritogenesis

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Application of Transcranial Magnetic Stimulation (TMS) in Motor Control and Learning

edited by

Sean Meehan

submission deadline 20 Nov 2025 | 1 articles | Viewed by 1151 | Submission Open

Keywords: transcranial magnetic stimulation; non-invasive; motor; sensorimotor; intracortical; neuroplasticity; basic neuroscience; clinical neuroscience; dual-site TMS

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

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