Dear Colleagues,

One of the most active fields of multidisciplinary research involves the rational design of systems capable of qualitatively and quantitatively reporting on certain substances or events of interest. These sensing platforms are of particular interest when they tackle important societal challenges, such as biomedical or environmental applications. For this reason, varied and powerful imaging techniques are continuously being developed to provide spatial localization of the sensor. Biological and biomedical insights, obtained through bioimaging and specific sensors, are revolutionizing the understanding of physiological and pathological events at different organizational levels, from single cells to in vivo animal models and studies in human volunteers.

The field of sensors for bioimaging is scientifically exciting since it is inherently multidisciplinary. The combination of developments blurring the frontiers of physics, chemistry, biophysics, biochemistry, and biology makes the field a unique collaborative environment. Furthermore, novel imaging techniques are being developed, reaching beyond the conventional techniques. Sensors specifically designed for super-resolution fluorescence microscopy, Raman microscopy, or mass spectrometry imaging exhibit great potential for advancement in the field of bioimaging. Likewise, we would like to pay special attention to multimodal imaging approaches. Sensors capable of providing chemical specificity and high-resolution imaging by combining different techniques in a single platform are among the most powerful approaches to date.

This Special Issue aims to collect research on recent tools for sensing in bioimaging in an exciting and multidisciplinary combination that may inspire other scientists to expand and advance in the field.

Prof. Dr. Angel Orte
Prof. Dr. María J. Ruedas-Rama
Guest Editors

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• fluorescent biosensors
• FRET sensors
• aptamers
• nanosensors
• fluorescent protein sensors
• FLIM microscopy
• super-resolution microscopy
• Raman microscopy
• mass spectrometry imaging
• NIR imaging
• NMR imaging
• PET imaging