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Review

Left Ventricular Hypertrophy and Ventricular Tachyarrhythmia: The Role of Biomarkers

by
Ljuba Bacharova
1,*,
Marta Kollarova
2,
Branislav Bezak
2,3,4 and
Allan Bohm
2,3,4
1
International Laser Center CVTI, 841 04 Bratislava, Slovakia
2
Premedix Academy, 811 02 Bratislava, Slovakia
3
National Institute for Cardiovascular Diseases, 833 08 Bratislava, Slovakia
4
Faculty of Medicine, Comenius University in Bratislava, 831 01 Bratislava, Slovakia
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2023, 24(4), 3881; https://doi.org/10.3390/ijms24043881
Submission received: 27 December 2022 / Revised: 8 February 2023 / Accepted: 14 February 2023 / Published: 15 February 2023
(This article belongs to the Special Issue Hunting for Prospective Molecular Approaches to Prevent Cardiac Arrhythmias)
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Abstract

Left ventricular hypertrophy (LVH) refers to a complex rebuilding of the left ventricle that can gradually lead to serious complications—heart failure and life-threatening ventricular arrhythmias. LVH is defined as an increase in the size of the left ventricle (i.e., anatomically), therefore the basic diagnosis detecting the increase in the LV size is the domain of imaging methods such as echocardiography and cardiac magnetic resonance. However, to evaluate the functional status indicating the gradual deterioration of the left ventricular myocardium, additional methods are available approaching the complex process of hypertrophic remodeling. The novel molecular and genetic biomarkers provide insights on the underlying processes, representing a potential basis for targeted therapy. This review summarizes the spectrum of the main biomarkers employed in the LVH valuation.
Keywords: left ventricular hypertrophy; ventricular tachyarrhythmias; biomarkers left ventricular hypertrophy; ventricular tachyarrhythmias; biomarkers

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MDPI and ACS Style

Bacharova, L.; Kollarova, M.; Bezak, B.; Bohm, A. Left Ventricular Hypertrophy and Ventricular Tachyarrhythmia: The Role of Biomarkers. Int. J. Mol. Sci. 2023, 24, 3881. https://doi.org/10.3390/ijms24043881

AMA Style

Bacharova L, Kollarova M, Bezak B, Bohm A. Left Ventricular Hypertrophy and Ventricular Tachyarrhythmia: The Role of Biomarkers. International Journal of Molecular Sciences. 2023; 24(4):3881. https://doi.org/10.3390/ijms24043881

Chicago/Turabian Style

Bacharova, Ljuba, Marta Kollarova, Branislav Bezak, and Allan Bohm. 2023. "Left Ventricular Hypertrophy and Ventricular Tachyarrhythmia: The Role of Biomarkers" International Journal of Molecular Sciences 24, no. 4: 3881. https://doi.org/10.3390/ijms24043881

APA Style

Bacharova, L., Kollarova, M., Bezak, B., & Bohm, A. (2023). Left Ventricular Hypertrophy and Ventricular Tachyarrhythmia: The Role of Biomarkers. International Journal of Molecular Sciences, 24(4), 3881. https://doi.org/10.3390/ijms24043881

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