Microsatellites with Macro-Influence in Ewing Sarcoma
Abstract
:1. Introduction
2. ETS Family of Transcription Factors
3. EWS/FLI in Ewing Sarcoma
4. EWS/FLI Fusions Mediate Gene Dysregulation via a GGAA Microsatellite Response Element
5. Microsatellite Constitution Influences EWS/FLI Binding and Gene Activation
6. GGAA Microsatellites Identify Other Potential EWS/FLI Targets and Epigenetically Regulated Enhancer Loci
7. The NR0B1 Microsatellite: A Functional Assessment Tool in Ewing Sarcoma Research
8. Microsatellite DNA in Cancer Pathogenesis
9. Polymorphic EWS/FLI GGAA Microsatellites: A Novel Approach to Ethnic Patterns of Ewing Sarcoma Susceptibility and Prognosis
10. Conclusions
Conflict of Interest
Acknowledgments
References
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Monument, M.J.; Johnson, K.M.; Grossmann, A.H.; Schiffman, J.D.; Randall, R.L.; Lessnick, S.L. Microsatellites with Macro-Influence in Ewing Sarcoma. Genes 2012, 3, 444-460. https://doi.org/10.3390/genes3030444
Monument MJ, Johnson KM, Grossmann AH, Schiffman JD, Randall RL, Lessnick SL. Microsatellites with Macro-Influence in Ewing Sarcoma. Genes. 2012; 3(3):444-460. https://doi.org/10.3390/genes3030444
Chicago/Turabian StyleMonument, Michael J., Kirsten M. Johnson, Allie H. Grossmann, Joshua D. Schiffman, R. Lor Randall, and Stephen L. Lessnick. 2012. "Microsatellites with Macro-Influence in Ewing Sarcoma" Genes 3, no. 3: 444-460. https://doi.org/10.3390/genes3030444