Human Hemorrhagic Fever Causing Arenaviruses: Molecular Mechanisms Contributing to Virus Virulence and Disease Pathogenesis
Abstract
:1. Introduction
4. Molecular Mechanisms Contributing to Virus Virulence and HF Disease Pathogenesis
4.1. Roles of the Glycoprotein (GP) and of the Host Cell Receptors in HF Disease Susceptibility and Pathogenesis
4.2. Role of the Polymerase (L) Protein in Viral Virulence
4.3. Role of the Nucleoprotein (NP) in Innate Immune Suppression
4.4. Roles of the Z Protein in Innate Immune Suppression and Viral Pathogenicity
6. Conclusions
Acknowledgements
Author Contributions
Conflicts of Interest
References
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Shao, J.; Liang, Y.; Ly, H. Human Hemorrhagic Fever Causing Arenaviruses: Molecular Mechanisms Contributing to Virus Virulence and Disease Pathogenesis. Pathogens 2015, 4, 283-306. https://doi.org/10.3390/pathogens4020283
Shao J, Liang Y, Ly H. Human Hemorrhagic Fever Causing Arenaviruses: Molecular Mechanisms Contributing to Virus Virulence and Disease Pathogenesis. Pathogens. 2015; 4(2):283-306. https://doi.org/10.3390/pathogens4020283
Chicago/Turabian StyleShao, Junjie, Yuying Liang, and Hinh Ly. 2015. "Human Hemorrhagic Fever Causing Arenaviruses: Molecular Mechanisms Contributing to Virus Virulence and Disease Pathogenesis" Pathogens 4, no. 2: 283-306. https://doi.org/10.3390/pathogens4020283