Next Article in Journal
DNA/MVA Vaccines for HIV/AIDS
Previous Article in Journal
Acceptability of Condoms, Circumcision and PrEP among Young Black Men Who Have Sex with Men: A Descriptive Study Based on Effectiveness and Cost
Previous Article in Special Issue
Advancing Toward HIV-1 Vaccine Efficacy through the Intersections of Immune Correlates
Vaccines 2014, 2(1), 138-159; doi:10.3390/vaccines2010138

DNA Immunization for HIV Vaccine Development

* ,
Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA
* Authors to whom correspondence should be addressed.
Received: 7 November 2013 / Revised: 8 February 2014 / Accepted: 10 February 2014 / Published: 25 February 2014
(This article belongs to the Special Issue HIV Vaccines)
View Full-Text   |   Download PDF [405 KB, uploaded 25 February 2014]


DNA vaccination has been studied in the last 20 years for HIV vaccine research. Significant experience has been accumulated in vector design, antigen optimization, delivery approaches and the use of DNA immunization as part of a prime-boost HIV vaccination strategy. Key historical data and future outlook are presented. With better understanding on the potential of DNA immunization and recent progress in HIV vaccine research, it is anticipated that DNA immunization will play a more significant role in the future of HIV vaccine development.
Keywords: HIV-1; AIDS; vaccine; DNA immunization HIV-1; AIDS; vaccine; DNA immunization
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote |
MDPI and ACS Style

Chen, Y.; Wang, S.; Lu, S. DNA Immunization for HIV Vaccine Development. Vaccines 2014, 2, 138-159.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here


[Return to top]
Vaccines EISSN 2076-393X Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert