The Models for Antimicrobial Compounds Testing
A special issue of Antibiotics (ISSN 2079-6382).
Deadline for manuscript submissions: closed (30 April 2024) | Viewed by 5966
Special Issue Editors
Interests: galleria mellonella model of infection; diabetic foot ulcers; staphylococcus aureus epidemiology; pseudomonas aeruginosa epidemiology; new antimicrobials; drug screening; antimicrobial resistance
Interests: antimicrobial resistance; bacterial virulence; biofilms; genomics; infections pathogenesis; food safety
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
More than 35000 people die from antimicrobial-resistant infections in the EU/EEA each year. The multidrug resistance hurdle combined with the fact that only two new classes of antibiotics were developed in the last 40 years, points out for the urgency to find alternatives to antibiotics. Novel compounds are generally screened in vitro to assess their effectiveness and potential toxicity, and then successful candidates proceed to pre-clinical trials using animal models, including insects like Galleria mellonella, and Drosophila melanogaster, nematodes like Caenorhabditis elegans, and mammals, before clinical trials in humans. To tackle the worldwide problem of antibiotic resistance, the establishment of infection models to study microbial infections and assess the efficacy of novel and conventional antimicrobials is crucial. This Special Edition focuses on “The Models for Antimicrobial Compounds Testing” and may include original research, review articles, and short communications. We are interested in qualitative and quantitative research on the use of different animal models for drug screening of new and conventional antimicrobials, and their use in resistance-related microbial infection research. Research on alternative in vitro models for drug screening is also welcome.
Dr. Isa D. Serrano
Dr. Manuela Oliveira
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- alternative in vitro models
- animal models
- antimicrobial resistance
- bacteria
- caenorhabditis elegans
- drosophila melanogaster
- drug screening
- fungi
- galleria mellonella
- microbial infection
- new antimicrobials
