Neuroinflammation and Oxidative Stress Regulation in Neurovascular Diseases: Current and Future Perspective

A special issue of Antioxidants (ISSN 2076-3921).

Deadline for manuscript submissions: closed (15 June 2022) | Viewed by 603

Special Issue Editors


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Guest Editor
1. Klinik für Neurologie, Universitätsklinikum Essen, Essen, Germany
2. Department of Pharmacology and Personalised Medicine, School for Mental Health and Neurosciences (MeHNs), Maastricht University, Maastricht, The Netherlands
Interests: neurovascular diseases; brain ischemia; reactive oxygen species; network pharmacology; neuroinflammation; oxidative stress

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Guest Editor
Molecular Neuroinflammation and Neuronal Plasticity Research Laboratory, Research Unit, Hospital Universitario Santa Cristina, Instituto de Investigación Sanitaria-Hospital Universitario de la Princesa, 28009 Madrid, Spain
Interests: neurovascular diseases; brain ischemia; tramatic brain injury; neuroinflammation; oxidative stress

Special Issue Information

Dear Colleagues,

Oxidative stress and neuroinflammation are common features of neurovascular and neurodegenerative diseases including stroke, vascular dementia, and Alzheimer’s disease, among others. In fact, increased oxidative stress levels due to the massive production of reactive oxygen/nitrogen species (ROS/RNS) directly lead to dysregulation of ROS/RNS-related signaling pathways, significantly contributing to the onset and progression of several neurovascular disorders. Moreover, oxidative stress-dependent tissue injury subsequently promotes the progression of a neuroinflammatory state characterized by the release of different pro-inflammatory mediators. In fact, both pathomechanisms are interconnected since specific inflammatory mediators use ROS production as signaling effectors. Thus, while dysregulated, these processes can contribute to neuronal cell loss and severe tissue damage in neurovascular diseases.

We invite you to submit your latest research findings either as an original or review article to our proposed Special Issue, “Neuroinflammation and Oxidative Stress regulation in Neurovascular diseases: Current and Future Perspectives”. We aim to gather the most recent research innovation regarding the role of oxidative stress and neuroinflammation in neurovascular disease. We encourage submissions including (i) different research models, i.e., in vitro, iPSC-derived cells, organoids, animal models, (ii) focusing on all nervous tissues and cell types, i.e., retina, brain, spinal cord, neurons, microglia, astrocytes, and (iii) using all types of molecular and cellular approaches, contributing to unravel pathophysiology and molecular mechanisms related to neurovascular disorders.

We look forward to your contribution.

Dr. Ana Casas Guijarro
Dr. Javier Egea
Guest Editors

Manuscript Submission Information

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Keywords

  • Neuroinflammation
  • Oxidative stress
  • Neurovascular diseases
  • Stroke
  • Vascular dementia

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Published Papers

There is no accepted submissions to this special issue at this moment.
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