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Antioxidants publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Redox Regulation of Immune and Inflammatory Responses

edited by

Yasuhiro Yoshida

submission deadline 10 Sep 2026 | 7 articles | Viewed by 15845 | Submission Open

Keywords: immune system; inflammatory responses; cytokines; immune cells; autoimmune disorders; chronic inflammation; and infections

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Plant Polyphenols in Human Health: Emerging Insights for Future Therapeutic Strategies

edited by

Vicente Micol

and

Francisco Javier Álvarez-Martínez

submission deadline 10 Sep 2026 | 5 articles | Viewed by 11089 | Submission Open

Keywords: polyphenols; antioxidant properties; anti-inflammatory effects; metabolic stress; chronic disease prevention; gut microbiota; polyphenols metabolites; bioavailability; skin health; novel therapies

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Advances in Oxidoreductases

edited by

Byung Cheon Lee

submission deadline 10 Sep 2026 | 3 articles | Viewed by 8798 | Submission Open

Keywords: oxidoreductase; redox enzyme; metabolic regulation; signaling; cancer; immune regulation

(This special issue belongs to the Section Antioxidant Enzyme Systems)

Modulation of Biochemical, Cellular and Physiological Mechanisms in Response to Oxidative Stress in Animals

edited by

Konstantinos Feidantsis

and

Vasiliki Sapanidou

submission deadline 15 Sep 2026 | 3 articles | Viewed by 7033 | Submission Open

Keywords: animals; cell signaling; metabolism; cell death responses; oxidative damage

From Field to Cell: Redox Mechanisms of Chemical Stressor Toxicity in Biological Systems

edited by

Marco G. Alves

and

Ariane Zamoner

submission deadline 20 Sep 2026 | 3 articles | Viewed by 8891 | Submission Open

Keywords: redox biology; environmental toxicology; chemical stressors; pesticides; redox signaling

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Metabolic Reprogramming and Epigenetic Crosstalk in the Tumor Microenvironment

edited by

Federico Pio Fabrizio

Lucia Anna Muscarella

Filippo Torrisi

and Sebastiano Giallongo

submission deadline 20 Sep 2026 | 1 articles | Viewed by 1250 | Submission Open

Keywords: metabolomics; tumor cell metabolism; tumor microenvironment; cell communication; cell signaling; epigenetics; post-translational modifications; cancer therapy

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Diabetic Kidney Disease

edited by John S. D. Chan

submission deadline 20 Sep 2026 | Viewed by 248 | Submission Open

Keywords: diabetic kidney disease; reactive oxygen species; mitochondrial oxidative stress; anti-oxidant molecules; molecular mechanisms

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Interplay of Microbiome and Oxidative Stress

edited by

Julio Plaza-Díaz

Lourdes Herrera-Quintana

and

Héctor Vázquez Lorente

submission deadline 30 Sep 2026 | 8 articles | Viewed by 26951 | Submission Open

Keywords: microbiome; oxidative stress; antioxidants; gut microbiota; free radicals; reactive oxygen species; gut–brain axis; dysbiosis; microbial metabolites; mitochondrial function; probiotics; microbe–host interactions

Effect of Oxidative Stress on Reproduction and Development—3rd Edition

edited by

Giulia Guerriero

and

Gerardino D’Errico

submission deadline 30 Sep 2026 | 8 articles | Viewed by 16751 | Submission Open

Keywords: free radicals and antioxidants; oxidative stress in male and female reproduction; mitochondria; gametogenesis; assisted reproduction; thermal fertility limit (TFL); climate change; one-health; biodiversity conservation and sustainability; reproduction; development and nutrigenomics; methods for reactive oxygen species detection and antioxidant property determination.

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Innovative Approaches to Neuroprotective Strategies: Targeting Oxidative Stress in Neurodegenerative Disorders

edited by

Tomasz Boczek

submission deadline 30 Sep 2026 | 5 articles | Viewed by 12946 | Submission Open

Keywords: oxidative stress; neurodegeneration; antioxidant therapy; mitochondrial dysfunction; redox signaling; reactive oxygen species (ROS); neuroprotection; Alzheimer’s disease; Parkinson’s disease; translational neuroscience

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Dietary Antioxidants, Oxidative Stress, and Women’s Reproductive Health

edited by

Miran Čoklo

submission deadline 30 Sep 2026 | 10 articles | Viewed by 12681 | Submission Open

Keywords: oxidative stress; women’s reproductive health; dietary antioxidants; female fertility; reproductive outcomes; polycystic ovary syndrome (PCOS); endometriosis; preeclampsia; nutritional interventions; bioactive compounds; lifestyle modifications

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Phenolic Antioxidants—2nd Edition

edited by

Adriano Costa de Camargo

and

Fereidoon Shahidi

submission deadline 30 Sep 2026 | 5 articles | Viewed by 10264 | Submission Open

Keywords: phenolics; phenolic compounds; antioxidants

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Phytochemical Profiling, Antioxidant Activity and Therapeutic Properties of Medicinal Plants

edited by

Lina Raudonė

submission deadline 30 Sep 2026 | 8 articles | Viewed by 9679 | Submission Open

Keywords: medicinal plants; phytochemicals; antioxidant activity; extraction optimization; functional foods and nutraceuticals; sustainability in phytotherapy

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Natural Antioxidants in Animal Nutrition

edited by

Lili Zhang

Xiang Zhong

, Chao Wang, Hao Zhang and Jingfei Zhang

submission deadline 30 Sep 2026 | 5 articles | Viewed by 9323 | Submission Open

Keywords: antioxidants; animal; growth; metabolism; nutrition; oxidative stress; plant extracts

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Diabetic Retinopathy and Oxidative Stress: Molecular Mechanisms, Diagnostic Strategies, and Advances in Antioxidant Therapies

edited by

Ángel Luis Ortega

and

Juan Gambini

submission deadline 30 Sep 2026 | 3 articles | Viewed by 9004 | Submission Open

Keywords: diabetic retinopathy; natural antioxidants; oxidative stress; epigenetic mechanisms; biomarkers; diagnostic methods

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Modulation of Gut Microbiota and Oxidative Stress to Counteract or Prevent Human Disease

edited by

Simone Carradori

Annalisa Chiavaroli

Alessandra Ammazzalorso

and

Marialucia Gallorini

submission deadline 30 Sep 2026 | 4 articles | Viewed by 8821 | Submission Open

Keywords: medicinal chemistry; enzyme modulators; neurodegenerative disorders; microbiota; gut–brain axis; inflammation; probiotic metabolomics; prebiotics; postbiotics; oxidative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Harnessing Antioxidants: Pioneering Approaches in Cardiovascular Disease Prevention and Therapy

edited by

Lanrong Bi

and

Guim Kwon

submission deadline 30 Sep 2026 | 2 articles | Viewed by 7468 | Submission Open

Keywords: oxidative stress; reactive oxygen species (ROS); antioxidants; cardiovascular diseases

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Innovations in Drug Delivery Systems for Antioxidant-Based Therapeutic Agents

edited by

Judit Váradi

submission deadline 30 Sep 2026 | 2 articles | Viewed by 6262 | Submission Open

Keywords: antioxidant; bioaccessibility/bioavailability; stability; controlled release; drug delivery system; nanoparticles; nano-carriers

Roles of Oxidative Stress in Human Pathophysiology

edited by

Alexandros Georgakilas

submission deadline 30 Sep 2026 | 4 articles | Viewed by 5423 | Submission Open

Keywords: oxidative stress; reactive oxygen species; redox signaling; antioxidants; inflammation; biomarkers; human diseases; therapy; pathology; pathophysiology

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Fertility and Infertility

edited by

Ying Cheong

submission deadline 30 Sep 2026 | 3 articles | Viewed by 5135 | Submission Open

Keywords: oxidative stress; reproduction; fertility; gametogenesis; embryo development; implantation; pregnancy; miscarriage; antioxidants; redox biology; reproductive ageing; placental function; developmental programming; pre-eclampsia

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress as a Therapeutic Target of Alzheimer’s Disease—2nd Edition

edited by

Leonardo Brunetti

and

Marcello Leopoldo

submission deadline 30 Sep 2026 | 3 articles | Viewed by 4564 | Submission Open

Keywords: Alzheimer's disease; oxidative stress; therapeutic target; antioxidant; neurodegeneration

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Natural Products to Mitigate Oxidative Stress and Inflammation in Non-Communicable Intestinal Diseases

edited by

Carlos Martins-Gomes

and

Amélia M. Silva

submission deadline 30 Sep 2026 | 2 articles | Viewed by 4364 | Submission Open

Keywords: natural bioactives; phytochemicals; oxidative stress; inflammation; non-communicable intestinal diseases; colorectal cancer; inflammatory bowel diseases; signalling pathways

Natural Antioxidants and Aquatic Animal Health—3rd Edition

edited by

Rui Jia

submission deadline 30 Sep 2026 | 7 articles | Viewed by 4059 | Submission Open

Keywords: natural antioxidants; oxidative stress; medicinal plants; aquatic animals; feed additives

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Advances in Anticancer Drugs Based on Phytocompounds with Antioxidant Properties—2nd Edition

edited by

Gabriela V. Vochita

and Lăcrămioara Opricǎ

submission deadline 30 Sep 2026 | 2 articles | Viewed by 3633 | Submission Open

Keywords: plant extracts; phytochemicals; anticancer; apoptosis; antioxidants; biocompatibility; nanoformulation; phytosomes

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Berry Antioxidants in Health and Disease—2nd Edition

edited by

Dorothy Klimis-Zacas

and

Sarah A. Johnson

submission deadline 30 Sep 2026 | 1 articles | Viewed by 3330 | Submission Open

Keywords: berries; antioxidants; polyphenols; berry metabolites; oxidative stress; chronic diseases; cardiovascular disease; metabolic syndrome; diabetes mellitus; cancer; neurodegenerative disease; gut microbiome

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Women’s Special Issue Series: Antioxidants in Human Health—2nd Edition

edited by

Simone Van Breda

and

Ruth Edge

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2978 | Submission Open

Keywords: oxidative stress; reactive oxygen species (ROS); antioxidants; vitamins; phytochemicals; molecular mechanisms; non-communicable diseases; human health; aging; clinical and public health applications

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox-Based Targeting of Signaling Pathways as a Therapeutic Approach

edited by

Seung-rock Lee

and Dhiraj Kumar Sah

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2857 | Submission Open

Keywords: cellular signaling; redox-based; therapeutic intervention; human disease; longevity

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Melatonin and Vitamin D: Dermal Messengers in Redox, Mitochondrial, and Regenerative Pathways

edited by

Konrad Kleszczyński

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2736 | Submission Open

Keywords: melatonin; metabolites of melatonin; vitamin D; wound healing; skin regeneration; skin aging; melanoma; skin diseases; mitochondria; oxidative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Antioxidants in Carcinogenesis: A Multifaceted Approach—2nd Edition

edited by

Fábio Rodrigues Ferreira Seiva

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2670 | Submission Open

Keywords: oxidative stress; carcinogenesis; reactive oxygen species (ROS); antioxidants; cancer therapeutics

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Bioactive Phytochemicals: Antioxidant Activities and Pharmacological Potential

edited by

Corneliu Tanase

and Mihai Babotă

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1828 | Submission Open

Keywords: bioactive phytochemicals; antioxidants; oxidative stress; anti-inflammatory activity; antimicrobial activity; pharmacological effects; redox signaling; bioavailability

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Redox Biomarkers in Inflammatory Diseases

edited by

María Candelaria Martín-González

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1638 | Submission Open

Keywords: redox biology; oxidative stress; inflammation; biomarkers; reactive oxygen species; antioxidant systems; immune dysregulation; cytokines; chronic inflammatory diseases; redox signaling; lipid peroxidation; mitochondrial dysfunction; clinical prognosis; precision medicine

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

The Antioxidants in Fermented Foods—2nd Edition

edited by

Yves Waché

Fares Boudjouan

and

Nadjet Benaida-Debbache

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1440 | Submission Open

Keywords: fermentation; microorganism metabolism; transformation of plant precursors; antioxidant activity

Studies on Antioxidants and Anti-Aging Substances Using Model Organisms and Cell Cultures

edited by

Yoshihiro H. Inoue

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1283 | Submission Open

Keywords: antioxidants; anti-aging substances and natural products; experimental animals; 3D cell culture models; organoids; acting mechanisms; antioxidant genes; autophagy; proteasome

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

The Role of Phytochemical Antioxidants in the Prevention and Management of Metabolic Disorders

edited by

Hae-Jeung Lee

and Miey Park

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1131 | Submission Open

Keywords: phytochemicals; metabolic disorders; antioxidants; inflammation; oxidative stress; bioactive compounds; natural products; molecular mechanisms; clinical interventions; metabolic health

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Biological Activities of Antioxidant Selenoproteins

edited by

Raquel Martin-Venegas

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1023 | Submission Open

Keywords: selenoproteins; selenium metabolism; microbial redox regulation; bacteria–host redox interactions; oxidative stress; antioxidant defence

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Something Is Rotten in the State of Redox—2nd Edition

edited by

and

submission deadline 30 Sep 2026 | Viewed by 896 | Submission Open

Keywords: antioxidants; antioxidant mechanisms; ageing and age-related diseases; oxidative stress; redox biology

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Potential of Phytotherapy in Cardiovascular Diseases

edited by

Valentina Oana Buda

submission deadline 30 Sep 2026 | Viewed by 555 | Submission Open

Keywords: phytotherapy; cardiovascular diseases; oxidative stress; antioxidants; medicinal plants; polyphenols; endothelial function; redox balance; natural compounds; plant-derived bioactives

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

ROS Levels and Thioredoxin Reductases

edited by

Jianqiang Xu

and Shui Guan

submission deadline 30 Sep 2026 | Viewed by 510 | Submission Open

Keywords: thioredoxin reductase; oxidative stress; antioxidants; bioactive materials; ferroptosis; disulfidptosis; necroptosis; apoptosis; autophagy; inflammation; diagnosis marker; oxidative stress; disulfide stress; redox regulation; nanomedicine

(This special issue belongs to the Section ROS, RNS and RSS)

NMR Spectroscopy for the Characterization of Foods: Applications in Antioxidant Research and Beyond

edited by

Giacomo Di Matteo

and

Federico Brigante

submission deadline 30 Sep 2026 | Viewed by 502 | Submission Open

Keywords: NMR spectroscopy; antioxidants; food science; bioactive compounds; oxidative stability; metabolomics; food processing; health promotion

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Dissecting Redox Duality: Insights into Antioxidant–Prooxidant Switching and Modulation Strategies for Better Health and Biotechnological Outcomes

edited by

Marília O. F. Goulart

submission deadline 30 Sep 2026 | Viewed by 433 | Submission Open

Keywords: redox duality; antioxidant paradox; oxidative stress modulation; therapeutic electrochemistry

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

New Paradigms in Oxidative Stress and Immune Responses in Infectious Diseases

edited by

Hao Wang

submission deadline 30 Sep 2026 | Viewed by 296 | Submission Open

Keywords: infection; oxidative stress; redox signaling; immune responses; immunopathology

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in the Molecular Pathogenesis of Neurodegenerative Disorders

edited by

Agueda A. Rostagno

and

Jorge Ghiso

submission deadline 30 Sep 2026 | Viewed by 288 | Submission Open

Keywords: Alzheimer’s disease; Parkinson’s disease; diabetic retinopathy; age-related macular degeneration; redox imbalance; Nrf2; vitamins and antioxidants dietary intake; homocysteine; glutathione

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Effects of Phytochemical Antioxidants in the Treatment of Chronic Inflammation and Metabolic Diseases

edited by

Ki Sung Kang

, Gabsik Yang and

Young-Joo Kim

submission deadline 30 Sep 2026 | Viewed by 169 | Submission Open

Keywords: phytochemicals; antioxidants; oxidative stress; molecular biology; systems biology

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Properties in Novel Feed Ingredients for Fish

edited by

Inês Guerreiro

submission deadline 10 Oct 2026 | 5 articles | Viewed by 17915 | Submission Open

Keywords: aquafeeds; fish; oxidative status; aquaculture; antioxidant; insect meal

Interplay Between Gut Microbiota and Oxidative Stress

edited by

Sunmin Park

submission deadline 10 Oct 2026 | 4 articles | Viewed by 6471 | Submission Open

Keywords: gut microbiota; redox; human health; gut homeostasis

Nutritional Antioxidants and Redox Regulation

edited by

Daniela-Saveta Popa

Ionel Fizesan

and

Roxana Banc

submission deadline 10 Oct 2026 | 1 articles | Viewed by 1362 | Submission Open

Keywords: oxidative stress; redox signaling; redox homeostasis; epigenetics; phytochemicals; bioaccessibility; bioavailability; plant extracts; dietary interventions; integrative medicine

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Activity of Medicinal Plants

edited by

Giovanna Baron

and

Larissa Della Vedova

submission deadline 15 Oct 2026 | 2 articles | Viewed by 2352 | Submission Open

Keywords: medicinal plants; natural antioxidants; phytochemicals

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Peptides

edited by

Daniel Carneiro Moreira

and

José Roberto de Souza de Almeida Leite

submission deadline 20 Oct 2026 | 9 articles | Viewed by 26447 | Submission Open

Keywords: structure–activity relationships; novel natural or synthetic sources; advanced delivery systems; roles in preventing or alleviating oxidative stress-related diseases.

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Role of Oxidative Stress in Eye Diseases

edited by

Tatsuya Mimura

submission deadline 20 Oct 2026 | 9 articles | Viewed by 13271 | Submission Open

Keywords: oxidative stress; reactive oxygen species; ocular disorders; age-related macular degeneration; retinopathy; glaucoma; cataracts; uveitis

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Activity of Natural Bioactive Compounds in Food and Agricultural Byproducts

edited by

Fabiana Pizzolongo

and

Filosa Stefania

submission deadline 20 Oct 2026 | 2 articles | Viewed by 2735 | Submission Open

Keywords: waste valorization; phytochemicals; functional ingredients; green extraction; nutritional enhancement; circular economy; health-promoting compounds; food fortification; shelf-life extension; oxidative stress

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

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