Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
4.5
2.7
Journals
Applied Sciences
Special Issues
Orofacial Pain: Diagnosis and Treatment
share announcement

Orofacial Pain: Diagnosis and Treatment

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".

Deadline for manuscript submissions: closed (20 April 2024) | Viewed by 5241

Special Issue Editor

Dr. Yaron Haviv

E-Mail Website
Guest Editor
Department of Oral Medicine, Sedation and Maxillofacial Imaging, Hadassah School of Dental Medicine, Hebrew University, Jerusalem 91905, Israel
Interests: orofacial pain; dental sleep medicine
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Over 39 million American adults suffer from chronic orofacial pain (OFP). OFP involves the head, face, and oral cavity and is associated with significant morbidity and high levels of healthcare utilization. OFP can be divided into three major categories:

(i) temporomandibular disorder (TMD) originating from the temporomandibular joint and/or from the masticatory muscles;

(ii) neuropathic pain that can originate from the central nervous system, such as trigeminal neuralgia, or the peripheral nervous system pain, mainly painful posttraumatic trigeminal neuropathies and other types such as post-herpetic neuralgia and burning mouth syndrome (BMS);

(iii) neurovascular orofacial pain, such as migraines and trigeminal autonomic cephalalgias (cluster headache, paroxysmal and continual hemicrania, SUNA, etc.).

OFP and headache can arise from multiple structures in the head and face areas. The variety of structures in the specific area, their proximity to each other, and the way they can cause various types of pain represent a diagnostic and therapeutic challenge.

Dr. Yaron Haviv
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • orofacial pain
  • temporomandibular disorder
  • neuropathic pain
  • trigeminal neuralgia
  • migraine
  • headache

Published Papers (4 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Editorial

Jump to: Research

3 pages, 166 KiB  
Editorial
Orofacial Pain, Diagnosis and Treatment
by Yaron Haviv
Appl. Sci. 2022, 12(21), 11026; https://doi.org/10.3390/app122111026 - 31 Oct 2022
Viewed by 1411
Abstract
I am pleased to introduce this Special Issue on “Orofacial pain, diagnosis and treatment” [...] Full article
(This article belongs to the Special Issue Orofacial Pain: Diagnosis and Treatment)

Research

Jump to: Editorial

11 pages, 668 KiB  
Article
Muscle Pain Sensitivity and Prevalence of Temporomandibular Disorders in Patients with Narcolepsy with Cataplexy: A Controlled Cohort Study
by Maria Lavinia Bartolucci, Serena Incerti Parenti, Fabio Pizza, Alessandro Maglioni, Stefano Vandi, Francesco Bortolotti, Giuseppe Plazzi and Giulio Alessandri-Bonetti
Appl. Sci. 2023, 13(12), 6917; https://doi.org/10.3390/app13126917 - 07 Jun 2023
Viewed by 973
Abstract
Disturbed nocturnal sleep contributes to the central sensitization of pain, thus predisposing to orofacial pain. Central disorders of hypersomnolence are characterized by excessive daytime sleepiness (EDS) not linked to impairment of nocturnal sleep or misaligned circadian rhythms. The main disorder of this group [...] Read more.
Disturbed nocturnal sleep contributes to the central sensitization of pain, thus predisposing to orofacial pain. Central disorders of hypersomnolence are characterized by excessive daytime sleepiness (EDS) not linked to impairment of nocturnal sleep or misaligned circadian rhythms. The main disorder of this group is narcolepsy type 1 (NT1), which seems to be related to alterations in pain perception mediation, supposedly caused by low orexin levels. The aim of this study was to evaluate the pain sensitivity and the prevalence of temporomandibular disorders (TMDs) in patients with NT1. After a 3-day hospital evaluation with laboratory polysomnography, 39 consecutive adult patients diagnosed with NT1 and 39 matched heathy controls were evaluated by means of Axis I and Axis II of the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) protocol. Furthermore, pain sensitivity was investigated by measuring the pressure pain thresholds (PPTs) on the head–neck muscles by means of a Fischer algometer. No significant differences were found between the PPTs of the two groups for all the muscles evaluated, nor in the prevalence of TMD diagnoses, but the NT1 group reported significantly higher values in the Patient Health Questionnaire (PHQ-9), corresponding to a depressive state. The present study presents an important investigation into NT1 patients, showing no alterations in pain perception and no differences in the prevalence of TMD diagnosis compared to the controls. Full article
(This article belongs to the Special Issue Orofacial Pain: Diagnosis and Treatment)
►▼ Show Figures

Figure 1

6 pages, 533 KiB  
Communication
Incidence of Chronic Pain following Oral Soft Tissue Biopsies: A Retrospective Study
by Adir Cohen, Rame Daod, Rakefet Czerninski, Naama Keshet, Robert Yanko, Andra Rettman, Yair Sharav, Doron J. Aframian and Yaron Haviv
Appl. Sci. 2023, 13(11), 6719; https://doi.org/10.3390/app13116719 - 31 May 2023
Viewed by 1055
Abstract
Soft tissue oral biopsies (STOB) are commonly performed in the medical field to obtain tissue samples for diagnostic purposes. However, like all invasive procedures, these biopsies may carry risks, such as the development of chronic long-lasting neuropathic pain. This study aims to examine [...] Read more.
Soft tissue oral biopsies (STOB) are commonly performed in the medical field to obtain tissue samples for diagnostic purposes. However, like all invasive procedures, these biopsies may carry risks, such as the development of chronic long-lasting neuropathic pain. This study aims to examine the occurrence of chronic pain following STOBs. A retrospective study was conducted on the medical records of 695 patients who underwent STOBs at the Maxillofacial Surgery Department of Hadassah Medical Center between the years 2013 and 2022. Demographic information, details of the procedure, histopathological diagnosis, and data related to post-procedure pain in the biopsy area were collected and analyzed. Out of the 695 patients, only 4 reports of chronic pain with mild intensity lasting more than three months following oral biopsy were documented, with incidence rate of 0.57%; all were females with a median age of 59 ± 2.0 years. The biopsies were taken from various sites and the common diagnoses were lichen planus, venous malformation, and fibromas. In conclusion, chronic pain after oral soft-tissue biopsies is rare, generally mild, and typically does not require extra therapy. These insights can aid clinicians and patients in making informed decisions about these procedures. Full article
(This article belongs to the Special Issue Orofacial Pain: Diagnosis and Treatment)
►▼ Show Figures

Figure 1

13 pages, 1256 KiB  
Article
Placebo or Nocebo Interventions as Affected by Hypnotic Susceptibility
by Yair Sharav, Yaron Haviv and Michael Tal
Appl. Sci. 2023, 13(2), 931; https://doi.org/10.3390/app13020931 - 10 Jan 2023
Viewed by 1287
Abstract
The purpose of the present study was to examine placebo and nocebo effects under hypnotic analgesia in lowly hypnotizable (LH) and highly hypnotizable (HH) subjects. A placebo and nocebo, obtained in a two-step intervention (verbal expectation and conditioning), were studied in 12 LH [...] Read more.
The purpose of the present study was to examine placebo and nocebo effects under hypnotic analgesia in lowly hypnotizable (LH) and highly hypnotizable (HH) subjects. A placebo and nocebo, obtained in a two-step intervention (verbal expectation and conditioning), were studied in 12 LH and 12 HH subjects under hypnosis. Visual analog scales (VASs) of pain intensity were recorded in response to short, painful electrical stimuli. VAS scores of placebo-produced analgesia differed significantly from nocebo-produced hyperalgesia in the LH subjects. Placebo intervention combined with hypnotic analgesia in LH subjects led to an analgesic degree similar to that achieved in the HH subjects. Yet, no difference was detected between the placebo and the nocebo effects on the HH subjects. Expectations for placebo and nocebo were significantly higher in the LH subjects than in the HH subjects. It seems that the HH subjects were more “tuned” to an inner trait that made them less susceptible to contextual cues, and therefore, more resistant to placebo/nocebo interventions. The ability to achieve hypnotic analgesia in LH subjects to the degree reached in the HH subjects under combined placebo intervention and hypnosis induction is of clinical significance. Combining placebo intervention with the induction of hypnotic analgesia could markedly improve analgesia, regardless of the patients’ hypnotic susceptibility. Full article
(This article belongs to the Special Issue Orofacial Pain: Diagnosis and Treatment)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-4
Back to TopTop