Bioengineering

Journal Browser

► Journal Browser

Electrochemical and Optical Sensors for Biological, Medical, and Environmental Research

Share This Special Issue

Special Issue Editors

Dr. Yueling Liu

E-Mail Website
Guest Editor

State Key Laboratory of Bioreactor Engineering, Biomedical Nanotechnology Center, School of Biotechnology, East China University of Science and Technology, Shanghai, China
Interests: electrochemical sensor; ion-selective electrodes; biosensor; fluorescent probe; nanosensor; cell imaging

Dr. Xiaotian Tan

E-Mail
Guest Editor

Beijing Institute of Collaborative Innovation (BICI), Beijing, China
Interests: biosensor; nanotechnology; biomedical imaging; biomedical optics; microfluidics; microfluidic immunoassay; bio-lasers

Special Issue Information

Dear Colleagues,

The field of electrochemical and optical sensors is experiencing explosive growth with a diverse range of host systems available for the selective complexation and detection of various guest species. It is encouraging to see research exploring new sensing principles and breaking the boundaries between multi-disciplines. Progress in nanobiotechnology and material science offers new functional materials which align the field to reliable, intelligent, and multifunctional sensors. The primary goal of this Special Issue is to develop a platform for researchers and readers to investigate all aspects of recent advancements in electrochemical and optical sensors for biological, medical, and environmental applications. Contributions focused on intercrossing and syncretizing multi-disciplines as well as smart devices are welcome. Both original articles and reviews are welcome.

I look forward to receiving your contributions.

Dr. Yueling Liu
Dr. Xiaotian Tan
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

electrochemical sensor
optical sensor
ion-selective electrode/optode
nanosensor
potentiometry
nanotechnology
spectroscopy
imaging
functional materials
nanomaterials

Published Papers (2 papers)

Download All Papers

Research

Jump to: Review

14 pages, 5618 KiB

Open AccessArticle

Immunosensing for Early Detection of Rheumatoid Arthritis Biomarkers: Anti-Cyclic Citrullinated Peptide Antibodies Based on Tilted-Fiber Bragg Grating Biosensor

by Hsin-Yi Wen, Chia-Chin Chiang, Rou-Yu Chen, Wei-Zhi Ni, Yu-Qiao Weng, Yao-Tsung Yeh and Hsiang-Cheng Hsu

Bioengineering 2023, 10(2), 261; https://doi.org/10.3390/bioengineering10020261 - 16 Feb 2023

Cited by 4 | Viewed by 2243

Abstract

Rheumatoid arthritis (RA) is regarded as a chronic, immune-mediated disease that leads to the damage of various types of immune cells and signal networks, followed by inappropriate tissue repair and organ damage. RA is primarily manifested in the joints, but also manifests in the lungs and the vascular system. This study developed a method for the in vitro detection of RA through cyclic citrullinated peptide (CCP) antibodies and antigens. The diameter of a tilted-fiber Bragg grating (TFBG) biosensor was etched to 50 μm and then bonded with CCP antigens and antibodies. The small variations in the external refractive index and the optical fiber cladding were measured. The results indicated that the self-assembled layer of the TFBG biosensor was capable of detecting pre- and post-immune CCP antigen and CCP peptide concentrations within four minutes. A minimum CCP concentration of 1 ng/mL was detected with this method. This method is characterized by the sensor’s specificity, ability to detect CCP reactions, user-friendliness, and lack of requirement for professional analytical skills, as the detections are carried out by simply loading and releasing the test samples onto the platform. This study provides a novel approach to medical immunosensing analysis and detection. Although the results for the detection of different concentrations of CCP antigen are not yet clear, it was possible to prove the concept that the biosensor is feasible even if the measurement is not easy and accurate at this stage. Further study and improvement are required. Full article

(This article belongs to the Special Issue Electrochemical and Optical Sensors for Biological, Medical, and Environmental Research)

► Show Figures

Figure 1

Review

Jump to: Research

27 pages, 13791 KiB

Open AccessReview

Recent Advances in Metal–Organic Frameworks (MOFs) and Their Composites for Non-Enzymatic Electrochemical Glucose Sensors

by Panpan Li, Yi Peng, Jinpeng Cai, Yang Bai, Qing Li and Huan Pang

Bioengineering 2023, 10(6), 733; https://doi.org/10.3390/bioengineering10060733 - 19 Jun 2023

Cited by 1 | Viewed by 1857

Abstract

In recent years, with pressing needs such as diabetes management, the detection of glucose in various substrates has attracted unprecedented interest from researchers in academia and industry. As a relatively new glucose sensor, non-enzymatic target detection has the characteristics of high sensitivity, good stability and simple manufacturing process. However, it is urgent to explore novel materials with low cost, high stability and excellent performance to modify electrodes. Metal–organic frameworks (MOFs) and their composites have the advantages of large surface area, high porosity and high catalytic efficiency, which can be utilized as excellent materials for electrode modification of non-enzymatic electrochemical glucose sensors. However, MOFs and their composites still face various challenges and difficulties that limit their further commercialization. This review introduces the applications and the challenges of MOFs and their composites in non-enzymatic electrochemical glucose sensors. Finally, an outlook on the development of MOFs and their composites is also presented. Full article

(This article belongs to the Special Issue Electrochemical and Optical Sensors for Biological, Medical, and Environmental Research)

► Show Figures