Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
3.7
4.7
Journals
Biomedicines
Special Issues
Cardiovascular Health in COVID-19: Pathophysiology and Therapeutic Perspective
share announcement

Cardiovascular Health in COVID-19: Pathophysiology and Therapeutic Perspective

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".

Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 8560

Special Issue Editor

Dr. Cristina Tudoran

E-Mail Website
Guest Editor
1. Department VII, Internal Medicine II, Discipline of Cardiology, University of Medicine and Pharmacy “Victor Babes” Timisoara, Timișoara, Romania
2. Department of Cardiology, County Emergency Hospital “Pius Brinzeu” Timisoara, Timișoara, Romania
Interests: heart failure; systemic hypertension; acute and chronic coronary syndrome; arrhythmias; management of patients with cardiovascular diseases; cardiovascular risk factors
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

As the COVID-19 pandemic lasts for almost 3 years, millions of people worldwide have been affected. The infection with the SARS-COV-2 virus rises serious healthcare problems aggravated by the not so uncommon long COVID-19 syndrome. Although many experts have tried to determine the mechanism responsible for the associated cardio-vascular alterations, there remain a lot of unknowns. The treatment of cardio-vascular pathologies caused by the SARS-COV-2 infection continues to be very challenging for healthcare professionals around the globe.

The scope of this special issue is to publish ground breaking researches on the pathophysiology and new therapeutic approaches in patients with and recovering from COVID-19.

Dr. Cristina Tudoran
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • COVID-19
  • long COVID-19 syndrome
  • cardio-vascular and pulmonary recovery
  • effort capacity
  • treatment
  • miocarditis
  • pericarditis
  • heart failure
  • pulmonary hypertension
  • arterial hypertension

Published Papers (4 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

Jump to: Review, Other

14 pages, 1194 KiB  
Article
COVID-19 Vaccines and Atrial Fibrillation: Analysis of the Post-Marketing Pharmacovigilance European Database
by Rosanna Ruggiero, Maria Donniacuo, Annamaria Mascolo, Mario Gaio, Donato Cappetta, Concetta Rafaniello, Giovanni Docimo, Consiglia Riccardi, Imma Izzo, Donatella Ruggiero, Giuseppe Paolisso, Francesco Rossi, Antonella De Angelis and Annalisa Capuano
Biomedicines 2023, 11(6), 1584; https://doi.org/10.3390/biomedicines11061584 - 30 May 2023
Viewed by 2694
Abstract
Atrial fibrillation (AF) has been described in COVID-19 patients. Recently, some case reports and US pharmacovigilance analyses described AF onset as a rare adverse event following COVID-19 vaccination. The possible correlation is unclear. We systematically analyzed the reports of AF related to COVID-19 [...] Read more.
Atrial fibrillation (AF) has been described in COVID-19 patients. Recently, some case reports and US pharmacovigilance analyses described AF onset as a rare adverse event following COVID-19 vaccination. The possible correlation is unclear. We systematically analyzed the reports of AF related to COVID-19 vaccines collected in the European pharmacovigilance database, EudraVigilance (EV), from 2020 to November 2022. We carried out descriptive and disproportionality analyses. Moreover, we performed a sensitivity analysis, excluding the reports describing other possible alternative AF causes (pericarditis, myocarditis, COVID-19, or other drugs that may cause/exacerbate AF). Overall, we retrieved 6226 reports, which represented only 0.3% of all those related to COVID-19 vaccines collected in EV during our study period. AF reports mainly referred to adults (in particular, >65 years old), with an equal distribution in sex. Reports were mainly related to tozinameran (54.04%), elasomeran (28.3%), and ChAdOx1-S (14.32%). The reported AF required patient hospitalization in 35% of cases and resulted in a life-threatening condition in 10% of cases. The AF duration (when reported) was highly variable, but the majority of the events had a short duration (moda = 24 h). Although an increased frequency of AF reporting with mRNA vaccines emerges from our study, other investigations are required to investigate the possible correlation between COVID-19 vaccination and the rare AF occurrence. Full article
(This article belongs to the Special Issue Cardiovascular Health in COVID-19: Pathophysiology and Therapeutic Perspective)
►▼ Show Figures

Figure 1

15 pages, 1011 KiB  
Article
Correspondence between Aortic and Arterial Stiffness, and Diastolic Dysfunction in Apparently Healthy Female Patients with Post-Acute COVID-19 Syndrome
by Cristina Tudoran, Felix Bende, Renata Bende, Catalina Giurgi-Oncu, Raluca Dumache and Mariana Tudoran
Biomedicines 2023, 11(2), 492; https://doi.org/10.3390/biomedicines11020492 - 8 Feb 2023
Cited by 4 | Viewed by 1588
Abstract
(1) Background: Abnormally increased arterial and aortic stiffness (AS and AoS), which are often associated with diastolic dysfunction (DD), represent common alterations in COVID-19. In this study, we aimed to assess, by transthoracic echocardiography (TTE) and pulse-wave velocity (PWV), the frequency of these [...] Read more.
(1) Background: Abnormally increased arterial and aortic stiffness (AS and AoS), which are often associated with diastolic dysfunction (DD), represent common alterations in COVID-19. In this study, we aimed to assess, by transthoracic echocardiography (TTE) and pulse-wave velocity (PWV), the frequency of these dysfunctions in patients with post-acute COVID-19 syndrome and to highlight potential correlations between their severity and multiple clinical and laboratory parameters. (2) Methods: In total, 121 women were included in our study, all of whom were younger than 55 and had been diagnosed with post-COVID-19 syndrome. Of those women, 67 also had metabolic syndrome (MS) (group A), whereas the other 54 did not (group B); 40 age-matched healthy subjects were used as controls (group C). (3) Results: Patients in group A had worse values of indexes characterizing AS and AoS and had more frequent DD compared to those from group B and group C (p < 0.0001). The statistical analysis evidenced significant associations between these indexes and the time that had elapsed since COVID-19 diagnosis, the factors that characterize the severity of the acute disease and those that specify MS. Multivariate regression analysis identified the following as the main independent predictors for DD: values of the AoS index, the C-reactive protein, and the triglyceride–glucose index. (4) Conclusions: Altered AS, AoS, and DD are common in patients with post-COVID-19 syndrome, especially with concurrent MS, and these parameters are apparently associated not only with the severity and time elapsed since COVID-19 diagnosis but also with MS. Full article
(This article belongs to the Special Issue Cardiovascular Health in COVID-19: Pathophysiology and Therapeutic Perspective)
►▼ Show Figures

Figure 1

Review

Jump to: Research, Other

15 pages, 3960 KiB  
Review
The Role of Hand-Held Cardiac Ultrasound in Patients with COVID-19
by Ziv Dadon, Shemy Carasso and Shmuel Gottlieb
Biomedicines 2023, 11(2), 239; https://doi.org/10.3390/biomedicines11020239 - 17 Jan 2023
Cited by 4 | Viewed by 1476
Abstract
The role of point-of-care ultrasound (POCUS) in patient management has been established in recent years as an important tool. It is increasingly used by multiple medical disciplines in numerous clinical settings, for different applications and diagnostic purposes and in the guidance of procedures. [...] Read more.
The role of point-of-care ultrasound (POCUS) in patient management has been established in recent years as an important tool. It is increasingly used by multiple medical disciplines in numerous clinical settings, for different applications and diagnostic purposes and in the guidance of procedures. The introduction of small-sized and inexpensive hand-held ultrasound devices (HUDs) has addressed some of the POCUS-related challenges and has thus extended POCUS’ applicability. HUD utilization is even more relevant in the COVID-19 setting given the operators’ infection risk, excessive workload concerns and general equipment contamination. This review focuses on the available technology, usefulness, feasibility and clinical applications of HUD for echocardiogram assessment in patients with COVID-19. Full article
(This article belongs to the Special Issue Cardiovascular Health in COVID-19: Pathophysiology and Therapeutic Perspective)
►▼ Show Figures

Figure 1

Other

Jump to: Research, Review

14 pages, 3904 KiB  
Case Report
Rhythm Disturbances in Post-Acute COVID-19 Syndrome in Young Men without Pre-Existing Known Cardiovascular Disease—A Case Series
by Ciprian Ilie Rosca, Horia Silviu Branea, Abhinav Sharma, Violeta Ariana Nicoras, Claudia Borza, Daniel Florin Lighezan, Stelian I. Morariu and Nilima Rajpal Kundnani
Biomedicines 2023, 11(4), 1146; https://doi.org/10.3390/biomedicines11041146 - 11 Apr 2023
Cited by 3 | Viewed by 2229
Abstract
Current data indicate the existence of post-acute COVID-19 syndrome frequently expressing as cardiovascular and respiratory health issues. The long-term evolution of these complications is not yet fully known or predictable. Among the most common clinical manifestations of post-acute COVID-19 syndrome are dyspnea, palpitations, [...] Read more.
Current data indicate the existence of post-acute COVID-19 syndrome frequently expressing as cardiovascular and respiratory health issues. The long-term evolution of these complications is not yet fully known or predictable. Among the most common clinical manifestations of post-acute COVID-19 syndrome are dyspnea, palpitations, and fatigue, in most cases being transient and without underlying any morphological or functional changes. A single-center retrospective observational study was performed on cases that had presented with new-onset cardiac symptoms post-COVID-19 infection. Records of three male patients without pre-existing chronic cardiovascular pathology who had presented for dyspnea, fatigue, and palpitations around four weeks post-COVID-19 acute phase were studied in detail. The three post-COVID-19 cases exhibited arrhythmic complications after completely healing from the acute phase of the infection. Palpitations, along with chest pain, and possible aggravation or appearance of dyspnea, with syncopal episodes, were found to be present. All the three cases were non-vaccinated against COVID-19 infection. Isolated case reports showing arrhythmic complications such as atrial fibrillation and ventricular tachycardia on a small number of patients with these complications indicate the need for arrhythmic evaluation of large groups of patients in the post-acute stage of the COVID-19 syndrome for a better understanding of the phenomenon and implicitly better care of these patients. It would also be useful to evaluate large groups of patients divided into vaccinated/non-vaccinated against COVID-19 categories to determine whether vaccination per se can provide protection in the occurrence of these types of complications. Full article
(This article belongs to the Special Issue Cardiovascular Health in COVID-19: Pathophysiology and Therapeutic Perspective)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-4
Back to TopTop